NEWS & EVENTS

Yet to Be Charted: Mapping the Lymphatic System Across Body Scales and Expertise Domains

Webinar

Description

This workshop will bring together clinicians and basic science researchers to explore the challenges and opportunities toward developing an open-access knowledge base and map of the human lymphatic system. We will emphasize the relevance of the fundamental understanding of lymphatic system structure and function, and its coordination and interactions with other body tissues and organs, for improving the clinical management of lymphatic dysfunction and diseases.

International experts will review the state of current fundamental and clinical understanding and the remaining challenges, including presenting the latest advances in lymphatic imaging at the clinical level, and the use of novel single cell technologies to map the lymphatic organs, discoveries of lymphatic system biomarkers, and will engage the audience in a collective effort to leverage modern data management and computational approaches.

For additional information, please visit:
https://bostonlymphaticsymposium.org/pre-symposium/
https://bostonlymphaticsymposium.org/pre-symposium/agenda/

Agenda

9:30 am
-
Welcome Remarks
Dhruv Singhal, MD, Elliot Chaikof MD, PhD, Zorina Galis, PhD

9:45 am
-
SESSION 1: WHERE ARE WE NOW?
Overview of challenges and opportunities - Zorina Galis, PhD

10:15 am
-
Anatomical Structures, Cell Types + Biomarkers (ASCT+B) knowledge bases for various human organs
Katy Börner, PhD

10:45 am
-
BREAK

11:00 am
-
Case Study: Mapping the Vasculature for the NIH Human Biomolecular Atlas (NIH HuBMAP)
Griffin Weber MD, PhD

11:30 am
-
Case Study: Spatial Mapping and ASCT+B for the Lymph Node (NIH HuBMAP)
Andrea Radtke, PhD

12:30 pm
-
LUNCH SESSION: An updated overview of the lymphatic vasculature functions in health and disease
Guillermo Oliver, PhD

1:00 pm
-
SESSION 2: WHERE DO WE WANT TO GO AND WHY?
Introduction to Session: Selen Catania, PhD, Timothy Padera, PhD

1:10 pm
-
Gross Lymphatic Anatomy
Moderators: Hiroo Suami, MD, Dhruv Singhal, MD, Maxim Itkin, MD

1:10 pm
-
Peripheral Lymphatics
Dhruv Singhal, MD

1:20 pm
-
Central Lymphatics
Maxim Itkin, MD

1:30 pm
-
RALLY: A call to identify and fill-in knowledge gaps in the field
Moderated by Griffin M. Weber, MD, PhD, Dhruv Singhal, MD, Maxim Itkin, MD

2:00 pm
-
BREAK

2:15 pm
-
Single Cell Analysis of Lymphatic Vasculature
Moderators: Michael Detmar, MD, Ellen Quardokus, MS

2:15 pm
-
Lymphatic endothelial identity, heterogeneity and role in regulation of inflammation and cancer
Michael Detmar, MD

2:25 pm
-
Single cell resolution of endothelium of dermal lymphatic vasculature and malformations
Taija Makinen, PhD

2:35 pm
-
Biochemical characterization of lymphedema and lipedema
Maija Hollmen, PhD

2:45 pm
-
RALLY: A call to identify and fill-in knowledge gaps in the field
Moderated by Ellen Quardokus, MS, Michael Detmar MD, Tajia Makinen, PhD, Majia Hollmen, PhD

3:20 pm
-
KEYNOTE: Brain’s solution for lymphatics, and brain wellness
Jeff Iliff, PhD

4:00 pm
-
Closing Remarks: Dhruv Singhal, MD, Zorina Galis, PhD