Autonomic Neural Mechanisms of Cardiopulmonary Regulation

The National Heart, Lung and Blood Institute (NHLBI), in partnership with the Office of Strategic Coordination (OSC), Office of the NIH Director (OD), convened a workshop on “Autonomic Neural Mechanisms of Cardiopulmonary Regulation”. The workshop brought together both national and international multi-disciplinary experts in basic, translational and clinical research in neuroscience and cardiopulmonary disorders, and representatives of academic institutions, federal and non-federal agencies. The workshop provided a forum discussing the latest advances, cutting-edge approaches and methodologies to identify the highest priority research gaps and opportunities to advance the field. The workshop objectives were to:

1. Critically evaluate the current state of knowledge of the roles that the Autonomic Neural System (ANS) plays in regulation of cardiopulmonary function in health and in pathophysiology of arrhythmias, heart failure and breathing disorders.
2. Identify approaches to further develop predictive markers of ANS dysfunction and to precisely target these mechanisms with neural-based antiarrhythmic, heart failure, pulmonary and sleep disorders therapies, including novel approaches to both subclinical and clinical heart failure and arrhythmia prevention.
3. Identify opportunities related to non-pharmacological neuromodulation and device-based therapies.
4. Provide a concise list of research opportunities based on identified gaps in the field and public health impact.

View the Workshop Agenda

Watch recordings of each session below on the "Recap" tab