NEWS & EVENTS
Cardiovascular Regenerative Medicine Symposium
September 27 - 28, 2017
NIH Main Campus
Description

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Thank you for your interest in the Seventh NHLBI Cardiovascular Regenerative Medicine Symposium taking place at the NIH main campus in Bethesda, Maryland on September 27−28, 2017. Register Online!

The event will bring together experts in the field to examine the challenging and critical questions that require answers as the field moves forward to clinical applications. The Symposium’s goals are to help the science and field move forward, to find consensus regarding the translation of stem cell biology and research into a clinical setting, and to inspire participants in their own work.

Topic Areas

  • Stem Cell Biology
  • Cardiovascular Development
  • Translational Cardiovascular Stem Cell Biology
  • Endogenous Heart Regeneration
  • New Technologies and Models
Agenda

7:00 a.m.
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Registration

8:00 a.m.
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Welcome and Opening Remarks

Manfred BoehmM.D.

National Heart, Lung, and Blood Institute

8:05 a.m.
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Remarks from the NHLBI Director

Gary HGibbonsM.D.

National Heart, Lung, and Blood Institute

8:15 a.m.
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Keynote Address
Cellular Reprogramming Approaches for Cardiovascular Disease

Deepak SrivastavaM.D.

Gladstone Institute of Cardiovascular Disease

University of California, San Francisco

9:00 a.m.
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Session I: Stem Cell Biology

Moderators: Charles E. Murry, M.D., Ph.D., and Victor J. Dzau, M.D.

9:05 a.m.
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Epigenetic Regulation, Stem Cells, and Disease Relevance

Rudolf JaenischM.D.

Whitehead Institute for Biomedical Research

Massachusetts Institute of Technology

9:25 a.m.
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Leveraging the Translation of iPS Cells

Ilyas SingeçM.D., Ph.D.

National Center for Advancing Translational Sciences

9:45 a.m.
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Therapeutic Targeting of Mesenchymal Stem/Stromal Cells in the Adult Mammalian Heart

Richard P. HarveyPh.D.

Victor Chang Cardiac Research Institute

University of New South Wales

10:05 a.m.
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Chromatin Remodeling and Vascular Fate

Courtney GriffinPh.D.

Oklahoma Medical Research Foundation

10:25 a.m.
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Panel Discussion

10:45 a.m.
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Break

11:00 a.m.
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Session II: Cardiovascular Development

Moderators: Beth Kozel, M.D., Ph.D., and Laura Niklason, M.D., Ph.D.

11:05 a.m.
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Regulation of Cardiopharyngeal Fate Specification in a Simple Chordate

Lionel ChristiaenPh.D.

New York University

11:25 a.m.
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Development of the Cardiopharyngeal Lineage in Zebrafish

Caroline E. BurnsPh.D.

Harvard Medical School

Massachusetts General Hospital

11:45 a.m.
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Generation of Atrial and Ventricular Cardiomyocytes From Human Pluripotent Stem Cells

Gordon M. KellerPh.D.

University Health Network, Toronto

12:05 p.m.
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Mechanisms of Endothelial Cell Regeneration

Luisa Iruela-ArispePh.D.

University of California, Los Angeles

12:25 p.m.
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Panel Discussion

12:45 p.m.
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Lunch (on your own)

1:30 p.m.
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Session III: Translational Cardiovascular Stem Cell Biology I

Moderators: Manfred Boehm, M.D., and Denis Buxton, Ph.D.

1:35 p.m.
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Allogeneic Transplantation Study of iPS Cell-Derived Cardiomyocytes Regenerates Primate Heart

Yuji ShibaM.D., Ph.D.

Institute for Biomedical Sciences

Shinshu University

1:55 p.m.
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Vascular Progenitor Cells in Engineered Tissues

Laura NiklasonM.D., Ph.D.

Yale School of Medicine

2:15 p.m.
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Maturation of Stem Cell-Derived Cardiomyocytes

Charles E. MurryM.D., Ph.D.

University of Washington

2:35 p.m.
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The Emerging Application of Stem Cells in Congenital Heart Disease Patients

Sunjay KaushalM.D., Ph.D.

University of Maryland Medical Center

2:55 p.m.
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Panel Discussion

3:15 p.m.
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Break

3:30 p.m.
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Poster Session

5:30 p.m.
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Adjourn

7:00 a.m.
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Registration

8:00 a.m.
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Session IV: Translational Cardiovascular Stem Cell Biology II

Moderators: Jason Kovacic, M.D., Ph.D., and Caroline E. Burns, Ph.D.

8:05 a.m.
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Regeneration of the Infarcted Pig Heart With Human Pluripotent Stem Cell-Derived Cardiomyocytes

Michael LaflammeM.D., Ph.D.

University Health Network, Toronto

University of Toronto

8:25 a.m.
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Stem Cells and Genomics for Precision Medicine

Joseph C. WuM.D., Ph.D.

Stanford University School of Medicine

8:45 a.m.
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Large-Scale GMP-Compatible Production of Stem Cell-Derived Cardiomyocytes

Joseph GoldPh.D.

Beckman Research Institute

9:05 a.m.
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Generation and Functional Characterization of Sodium Iodide Symporter Transgenic Rhesus-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Cynthia E. DunbarM.D.

National Heart, Lung, and Blood Institute

9:25 a.m.
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Panel Discussion

9:45 a.m.
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Break

10:00 a.m.
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Session V: Endogenous Heart Regeneration

Moderators: Manfred Boehm, M.D., and Joshua Hare, M.D.

10:05 a.m.
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Redox Regulation of Cardiomyocyte Renewal

Hesham SadekM.D., Ph.D.

The University of Texas Southwestern Medical Center

10:25 a.m.
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An Evolutionarily Conserved Pathway of Heart Regeneration

Richard T. LeeM.D.

Harvard University

10:45 a.m.
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Innate Heart Regeneration

Kenneth D. PossPh.D.

Duke University Medical Center

11:05 a.m.
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Hippo Signaling in Heart Regeneration

James FMartinM.D., Ph.D.

Baylor College of Medicine

Texas Heart Institute

11:25 a.m.
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Panel Discussion

11:45 a.m.
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Lunch (on your own)

12:30 p.m.
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Session VI: New Technologies and Models

Moderators: Joseph Gold, Ph.D., and Ilyas Singeç, M.D., Ph.D.

12:35 p.m.
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New Strategies for Accelerating Cardiac Regeneration

Nadia RosenthalPh.D., FMedSci., FAAHMS

The Jackson Laboratory (Bar Harbor, Maine)

12:55 p.m.
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DNA Sequence Variations in iPSCs

Paul LiuM.D., Ph.D.

National Human Genome Research Institute

1:15 p.m.
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Human Pluripotent Stem Cells in Understanding Genetic Cardiovascular Disease and Effects of Drugs

Christine MummeryPh.D.

Leiden University Medical Center

1:35 p.m.
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Genome Engineering in Human iPS Cells to Model and Treat Disease

Bruce R. ConklinM.D.

Gladstone Institute of Cardiovascular Disease

University of California

1:55 p.m.
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Panel Discussion

2:15 p.m.
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Session VII: Clinical Translation Roundtable Discussion

Moderators: Joseph C. Wu, M.D., Ph.D., and Cynthia E. Dunbar, M.D.

2:20 p.m.
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Lessons from Current Trials That Can Guide the Design of Pivotal Trials

Joshua HareM.D.

University of Miami Miller School of Medicine

2:40 p.m.
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The Regulatory Approach for Cardiopoietic Stem Cell Therapy

Atta Behfar, M.D., Ph.D.

Mayo Clinic Graduate School of Biomedical Sciences

3:00 p.m.
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Future Directions in Cell Therapy

Denis BuxtonPh.D.

National Heart, Lung, and Blood Institute

3:20 p.m.
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Regenerative Medicine Provisions of the 21st Century Cures Act: Catalyst for Partnerships and Innovation

Amy P. Patterson, M.D.

National Heart, Lung, and Blood Institute

3:40 p.m.
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Jason Kovacic, M.D., Ph.D.

Ichan School of Medicine

Mount Sinai Medical Center

4:00 p.m.
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Closing Remarks

4:05 p.m.
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Adjourn