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The U.S. Food and Drug Administration approved two new gene therapies to treat sickle cell disease — one a gene-editing and the other a gene-addition approach. Nearly 100,000 people in the United States — and millions worldwide — have been diagnosed with this painful, life-threatening genetic blood disease. To help explain the historic importance...

Today, the U.S. Food and Drug Administration (FDA) approved two gene therapies for the treatment of sickle cell disease in patients 12 years and older. About 100,000 Americans and millions of people around the world have sickle cell disease , a hereditary disease common among those whose ancestors come from sub-Saharan Africa, Mediterranean...

NIH-supported study shows better sleep, blood pressure after adenotonsillectomy Surgical removal of the tonsils and adenoids in children with snoring and mild breathing problems during sleep appears to improve their sleep, quality of life, and blood pressure a year after surgery, a clinical trial supported by the National Institutes of Health has...

Findings highlight importance of early monitoring and management of hypertension during and after pregnancy Hispanic/Latina women with a history of hypertensive disorders of pregnancy (HDP) – conditions marked by high blood pressure during pregnancy – are more likely to have abnormalities in their heart structure and function decades later when...

Findings highlight insufficient sleep as a modifiable risk factor for type 2 diabetes Chronic insufficient sleep can increase insulin resistance in otherwise healthy women, with more marked effects in postmenopausal women, according to a study funded by the National Institutes of Health. The findings, published in Diabetes Care, highlight the...

NIH-supported findings suggest improved techniques for rescue breathing could save more lives The ventilation technique, also known as rescue breathing, commonly used during cardiopulmonary resuscitation (CPR) for people with cardiac arrest is often performed poorly by professional emergency responders, and this ineffective strategy is linked to...

Findings suggest potential benefit of giving more blood to patients A National Institutes of Health supported study found that the type of transfusion approach used to support adults who developed anemia after a heart attack did not make a significant difference in their likelihood of having another heart attack or dying within 30 days...

NIH-funded study predicts older and Black adults will suffer most Cardiovascular-related deaths due to extreme heat are expected to increase between 2036 and 2065 in the United States, according to a study supported by the National Institutes of Health. The researchers, whose work is published in Circulation , predict that adults ages 65 and older...

Novel conditioning agent shows promise in animal models of sickle cell disease What: Researchers at the National Institutes of Health have created a novel gene therapy procedure that could preserve fertility in people with sickle cell disease and other genetic blood conditions. Infertility is a high-risk and long-term side effect associated with...

NIH-supported research provides broader understanding of how cardiovascular disease risk manifests following pregnancy Having obesity before and during early pregnancy appears to be a strong indicator of risk for developing future cardiovascular disease and was significantly linked with adverse outcomes during pregnancy such as high blood pressure...