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Director Dr. Francis Collins sings about the future of personalized medicine to attendees of the NHLBI's 11th annual Public Interest Organization Meeting on May 24, 2010.
<body> <div xml:lang="en" style="b1"> <p begin="00:00:14" end="00:00:28">Susan is to blame for this because she suggested that you all were of the sort that might actually adjust to a little bit of foolish singing at the end and that's the only kind of singing I do. So, good thing for you.</p>
<p begin="00:00:28" end="00:00:39">This is a song about the future for personalized medicine. Remember I said that thousand dollar genome is coming pretty soon?</p>
<p begin="00:00:39" end="00:00:58">That means each of you will have the chance, maybe in the next five or six years, to have your entire genome read out, all six billion of those letters of your DNA code, and then you'll have to figure it out what it means,</p>
<p begin="00:00:58" end="00:01:05">...and that's a bit of a challenge. A few people have already gone through this experience and they've been a little flummoxed trying to make sense of the data. Well we will all be.</p>
<p begin="00:01:05" end="00:01:20">So this is a song that if you can imagine yourself having just received your genome. Basically you're sitting in front of your computer, you're sort of scrolling through the pages and what do you see?</p>
<p begin="00:01:20" end="00:01:30">A lot of A, C, G, and T, in various orders and trying to figure out exactly 'What does this mean?' So this is your song.</p>
<p begin="00:01:30" end="00:01:40">And I need a little bit of help on one part of this song because it goes up to a high C sharp and that's a little outside my normal range.</p>
<p begin="00:01:40" end="00:01:53">You will feel it coming and you will help me, I sure hope anyway. You'll know what you have to do. So here's the song of looking at your genome.</p>
<p begin="00:01:53" end="00:02:21">As I walk along the pages, In all six billion places, Upon my computer screen. Am I built for strong endurance? Or loss of life insurance? Am I a mere machine? </p>
<p begin="00:02:21" end="00:02:55">I'm a walking through the genes, Don't know what all this means, Oh what can the meaning be behind that G and T? And I wonder, I wa wa wa wa wonder, why why why why why why, you've got an A and I've got a C there,</p>
<p begin="00:02:55" end="00:03:18">What does that say? Amazing DNA a D-D-D-D DNA </p>
<p begin="00:03:18" end="00:03:35">So I'm glad to know I've got some, Of what Crick and Watson, Found and brought them fame. Use your own imagination, Despite variation, We're really much the same </p>
<p begin="00:03:35" end="00:03:58">I'm a walking through the genes, don't know what all this means, Oh what can the meaning be behind that G and T? And I wonder, (help me) I wa wa wa wa wonder, why why why why why why, </p>
<p begin="00:03:58" end="00:04:20">you've got an G and I've got a C there. What does that say? Amazing DNA a D-D-D-D DNA, A D-D-D-D DNA, A D-D-D-D DNA</p>