Healthcare providers, patients, and policy experts seeking information about appropriate COVID-19 treatment may consult treatment guidelines developed by a panel of U.S. physicians, statisticians, and other experts. These guidelines are based on published and preliminary data and the clinical expertise of the panelists, many of whom are frontline clinicians caring for COVID-19 patients. The guidelines are updated as new data are published in peer-reviewed scientific literature and as other authoritative information emerges.
The CDC has also published Interim Clinical Guidance for Management of Patients with Confirmed Coronavirus Disease (COVID-19) for clinicians caring for patients with confirmed infection with SARS-CoV-2, the virus that causes COVID-19. This guidance covers clinical presentation, testing, diagnosis, and clinical management and treatment, among other topics. CDC updates this interim guidance when more information becomes available.
Several COVID-19 research initiatives leverage NHLBI-supported clinical trial networks and research study cohorts that existed before the COVID-19 pandemic started.
The Collaborating Network of Networks for Evaluating COVID-19 and Therapeutic Strategies (CONNECTS) builds on our existing clinical research networks to better understand the risk of severe illness from COVID-19 and to identify therapies that will slow or halt the disease progression and speed recovery.
As a result of these efforts, a number of clinical trials and observational studies are underway, or have been completed, including: