Immunology/Molecular Biology Postdoctoral Position
Laboratory of Molecular Immunology and the Immunology Center
National Heart, Lung and Blood Institute
National Institutes of Health (NIH)
Department of Health and Human Services
Dr. Warren J. Leonard, Laboratory of Molecular Immunology and the Immunology Center, National Heart, Lung and Blood Institute (NHLBI), NIH, Bethesda, MD is recruiting a postdoctoral researcher to work in the area of molecular immunology. Having previously discovered that mutations in the common cytokine receptor γ chain, γc, result in X-linked severe combined immunodeficiency in humans and that γc is a shared component of multiple cytokine receptors, the lab focuses on the cytokines that share γc (IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21) and the IL-7-related cytokine, TSLP, with the goal of elucidating new activities, regulatory mechanisms, and connections to human disease.
The lab has generated valuable transgenic, knockout, and knockin mice and a wealth of other valuable reagents and also uses normal donor and patient cells and aims to elucidate physiological responses as well as normal and pathological mechanisms, including related to signal transduction, gene regulation, and epigenetics. State-of-the-art methodologies are used in human and murine systems, in vitro and in vivo, including CRISPR/Cas9 as well as a range of next generation sequencing approaches, including ChIP-Seq, RNA-Seq, ATAC-Seq, as well as whole exome and whole genome methodology.
The ideal candidate will have a reasonable level of independence, be innovative and interactive, and will have a strong background in immunology and/or molecular biology. The candidate must have received a Ph.D. and/or an M.D. degree. The candidate will be supported with the excellent intramural NIH fellowship in a stimulating and interactive research environment at NIH. Applicants must be within 5 years of their doctoral degree.
To apply, email your curriculum vitae and names with contact information of three references to: