DIR Core Facilities

Core Facilities provide scientific resources, cutting-edge technologies and novel approaches to support DIR scientists. Availability of specialized expertise creates a robust environment for conducting a wide range of studies and accelerates the pace at which scientific discovery can take place.

Our Programs

Animal MRI Core

The Animal Magnetic Resonance Imaging (MRI) Core specializes in cardiovascular imaging of mice and rats. It performs all aspects of imaging studies, from planning to data analysis and interpretation. The Core works with investigators to tailor imaging studies to individual study needs. It also performs a wide variety of studies, including cardiac function and anatomy, stress testing and vascular imaging.


Animal Surgery and Resources Core

The Animal Surgery and Resource Core services for NHLBI research animals include animal model development, surgery, surgical support, imaging support, and post-operative care, as well as technical services such as radiography, blood & tissue collection. These services include both rodents and large animals.


Biochemistry Core

The mission of the Biochemistry Core is to provide expert services and consultation in biochemical enzyme assays and protein purification. All users are provided with on-site instrumentation training and if necessary, assistance with data processing and analyses.


Bioinformatics and Computational Biology

The Bioinformatics and Computational Biology Core facility at the NHLBI facilitates, amplifies, and accelerates biological and medical research and discovery through the application of the latest bioinformatics methods and technologies. This mission is achieved by delivering high quality and comprehensive support for experimental design, analysis and visualization in a timely fashion. The Core is responsive to research scientists’ needs and effectively evolve with advances in the field.


Biophysics Core

The Biophysics Core’s mission is to provide support in the study of macromolecular interactions, dynamics, and stability by offering consultations, training, professional collaborations, and instrument access. This Core assists NHLBI researchers with comprehensive biophysical characterization of biomolecules, including proteins, polynucleotides, nanoparticles, and their ligands.