Expert Panel Report 4 (EPR-4) Working Group

National Asthma Education and Prevention Program Coordinating Committee

The National Asthma Education and Prevention Program Coordinating Committee (NAEPPCC) Expert Panel 4 (EPR-4) Working Group was established in 2018 to update the 2007 Guidelines for the Diagnosis and Management of Asthma, Expert Panel Report 3 (EPR-3). The EPR-4 Working Group members will use findings from five systematic reviews to update the guidelines. The topic areas include:

NHLBI engaged the Agency for Healthcare Research and Quality (AHRQ) and provided support for rigorous systematic evidence reviews through the AHRQ Evidence-based Practice Centers. The EPR-4 Working Group will follow the Institute of Medicine’s recommendations and standardsfor using systematic evidence reviews in the development of trustworthy guidelines.

Roster
- Expert Panel Report 4 (EPR-4) Working Group

NAEPPCC EPR-4 Working Group

Chair
- Expert Panel Report 4 (EPR-4) Working Group

Michelle M. Cloutier, M.D.

University of Connecticut School of Medicine

Hartford, CT

Members
- Expert Panel Report 4 (EPR-4) Working Group

Alan Baptist, M.D., M.P.H.

University of Michigan

Ann Arbor, MI

 

Kathryn Blake, Pharm.D., BCPS, FCCP, CIP

Nemours Children's Specialty Care

Jacksonville, FL

 

Edward G. Brooks, M.D.

University of Texas Health Science Center

San Antonio, TX

 

Emily DiMango, M.D.

Columbia University Medical Center

New York, NY

 

Ann Dixon, M.A., B.M., B.Ch.

University of Vermont

Burlington, VT

 

Kurtis S. Elward, M.D., M.P.H., FAAFP

Virginia Commonwealth University

Charlottesville, VA

 

Tina Hartert, M.D., M.P.H.

Vanderbilt School of Medicine

Nashville, TN

 

Jerry Krishnan, M.D., Ph.D.

University of Illinois Hospital & Health Sciences System

Chicago, IL

 

Robert Frederick Lemanske, M.D.

University of Wisconsin School of Medicine and Public Health

Madison, WI

 

Daniel R. Ouellette, M.D., FCCP

Henry Ford Health System

Detroit, MI

 

Wilson Pace, M.D., FAAFP

University of Colorado School of Medicine

Aurora, CO

 

Michael Schatz, M.D., M.S.

Kaiser Permanente

San Diego, CA

 

Neil Skolnik, MD

Abington Jefferson Health

Abington, PA

 

Tyra Bryant Stephens, M.D.

Children's Hospital of Philadelphia

Philadelphia PA

 

Jim Stout, M.D., M.P.H.

University of Washington

Seattle, WA

 

Stephen Teach, M.D., M.P.H.

George Washington University

Washington, DC

 

Craig Umscheid, M.D., M.S.C.E.

Penn Medicine

Philadelphia, PA

 

Colin G. Walsh, M.D., M.A.

Vanderbilt University Medical Center

Nashville, TN

Mensah GA, Kiley JP, Gibbon GH. Generating Evidence to Inform an Update of Asthma Clinical Practice Guidelines: Perspectives from the National Heart, Lung, and Blood Institute. J Allergy Clin Immunol 2018. Article in Press: 10.1016/j.jaci.2018.07.004

Ballas ZK. Asthma Clinical Practice Guidelines: Time for an update. J Allergy Clin Immunol 2018: Article in Press: 10.1016/j.jaci.2018.07.008

Rice JL, Diette GB, Suarez-Cuervo C, Brigham EP, Lin SY, Ramanathan M Jr, Robinson KA, Azar A. Allergen-Specific Immunotherapy in the Treatment of Pediatric Asthma: A Systematic Review. Pediatrics. 2018 May;141(5). pii:e20173833. doi: 10.1542/peds.2017-3833. Epub 2018 Mar 23. Review. PubMed PMID: 29572287.

Sobieraj DM, Baker WL, Nguyen E, et al. Association of inhaled corticosteroids and long-acting muscarinic antagonists with asthma control in patients with uncontrolled, persistent asthma: a systematic review and meta-analysisexternal link [published online March 19, 2018]. JAMA. doi:10.1001/jama.2018.2757.

Sobieraj DM, Weeda ER, Nguyen E, et al. Association of inhaled corticosteroids and long-acting β-agonists as controller and quick relief therapy with exacerbations and symptom control in persistent asthma: a systematic review and meta-analysisexternal link [published online March 19, 2018]. JAMA. doi: 10.1001/jama.2018.2769.

Leas BF, D’Anci KE, Apter AJ, et al. Effectiveness of indoor allergen reduction in the management of asthma: a systematic review.external link The Journal of Allergy and Clinical Immunology. 13 Feb 2018. [Epub ahead of print.] http://www.jacionline.org/article/S0091-6749(18)30223-9/abstract. DOI: https://doi.org/10.1016/j.jaci.2018.02.001.

Wang Z, Pianosi P, Keogh K, et al. The Diagnostic Accuracy of Fractional Exhaled Nitric Oxide Testing in Asthma: A Systematic Review and Meta-analysesexternal link. Mayo Clinic Proceedings. ePub ahead of print. DOI: http://dx.doi.org/10.1016/j.mayocp.2017.11.012.

Lin SY, Azar A, Suarez-Cuervo C, Diette GB, Brigham E, Rice J, Ramanathan M Jr, Robinson KA. Role of sublingual immunotherapy in the treatment of asthma: An updated systematic review. Int Forum Allergy Rhinol. 2018 Jun 9. doi: 10.1002/alr.22152. [Epub ahead of print] PubMed PMID: 29885036.

Resources
- Expert Panel Report 4 (EPR-4) Working Group