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CT/OS ENROLLMENT STATUS

Recruitment for the Women's Health Initiative (WHI) began in September 1993. The last participant in the CT enrolled in December 1998. The CaD trial enrolled women who were already in the HT and/or DM trials for up to 2 years and their randomizations continued until July 31, 2000. The OS completed enrollment on December 31, 1998.

recruitment numbers: H R T 27,347; D M  48,835; C a D 36,282;  Observational Study  93,676

Recruitment Issues

Each clinical center faced its individual challenge in recruiting participants especially for the HT component. In some areas of the country, hormones are routinely prescribed to alleviate menopausal symptoms and thus finding eligible women to participate in the HT was a challenging endeavor. In other areas, women are confused about the risks of taking hormones due to reports of a potential increase in breast cancer risk. The WHI was the first clinical trial to address and answer the benefits and the potential adverse effects of HT.


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