NIH DIrector's Pioneer Award Program
To stimulate high-risk, high-impact medical research, the National Institutes of Health (NIH) is inviting nominations for the NIH Director's Pioneer Award Program, part of a series of far-reaching initiatives known collectively as the NIH Roadmap for Medical Research.
Six new data sets have been added to the current Limited Access Data Web site:
Artery Surgery Study (CASS)
This project included two components, a registry of patients undergoing angiography at participating sites and a randomized trial component. The primary objective of the registry was to provide information regarding the effects of coronary artery surgery on patients with ischemic heart disease within the clinical course of treatment.
Arrhythmia Suppression Trial (CAST)
This trial sought to evaluate the efficacy and safety of arrhythmia suppression therapy in patients with asymptomatic or mildly symptomatic ventricular arrhythmia after myocardial infarction.
Frequency Ventilation in Premature Infants (HIFI)
This project evaluates the hypothesis that high frequency oscillatory ventilation in preterm infants would reduce the incidence of mortality and pulmonary complications compared to conventional mechanical ventilation.
Risk Factor Intervention Trial (MRFIT)
This trial sought to evaluate the effect of multiple risk factor intervention on mortality from coronary heart disease in high risk men.
Respiratory Distress Syndrome Clinical Network (ARDSNet)
The ARDS Network is a consortium of clinical centers and a coordinating center to design and test novel therapies for the treatment of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS).
Approaches to Stop Hypertension - Sodium (DASH-Sodium) Trial
The primary objective of the DASH-Sodium Trial was to test the effects of two dietary patterns and three sodium intake levels on blood pressure in adult men and women with blood pressure higher than optimal or at stage 1 hypertension (systolic 120-159 mm Hg and diastolic 80-95 mm Hg).