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Neal Young, M.D., MACP

Neal Young photoChief of the Hematology Branch, NHLBI

E-mail: youngns@mail.nih.gov

Neal S. Young, M.D., MACP is the Chief of the Hematology Branch of the National Heart, Lung and Blood Institute. The Hematology Branch conducts clinical and basic research in the areas of hematopoiesis, bone marrow failure, hematopoietic stem cell transplantation, graft-versus-host disease, and gene therapy for blood diseases.

Dr. Young received his A.B. from Harvard and M.D. from the Johns Hopkins School of Medicine. Following internal medicine residency at Massachusetts General Hospital, Dr. Young came first to the National Institutes of Health to learn protein biochemistry in the laboratory of Nobel Prize winner Christian Anfinsen. After a fellowship in hematology at Barnes Hospital of Washington University in St. Louis, Dr. Young returned to NHLBI for a second post-doctoral fellowship in molecular biology under Dr. Arthur Nienhuis. He developed an interest in aplastic anemia during this time and established an independent section in the former Clinical Hematology Branch to study human bone marrow failure, both its treatment and pathogenesis. On Dr. Nienhuis? departure to become Director of St. Jude Children?s Research Hospital, the Hematology Branch was constituted and has now grown to four independent sections under world renowned principal investigators. The clinic of the Branch is perhaps the major referral center for bone marrow failure syndromes in the world.

Accomplishments from Dr. Young?s laboratory have included the successful development of immunosuppressive therapies for patients with aplastic anemia and related syndromes; the description of B19 parvovirus as an agent of human disease, including development of a vaccine now in clinical trials; the elucidation of both the immunology and genetics of acquired aplastic anemia, including the recent first demonstration of pathogenic mutations in TERT, the gene for the telomerase enzyme. Dr. Young has published almost 300 research articles and more than 100 reviews and book chapters; he has written or edited ten monographs, including a novel textbook of hematology. Dr. Young is a member of many honorary societies, including the American Society of Clinical Investigation and the American Association of Physicians, he is a Master of the American College of Physicians, and the recipient many named lectureships in hematology and medicine. He is co-discoverer on seven patents relating to parvoviruses and also the detection of mutations in human single hematopoietic cells. Finally, Dr. Young?s has mentored dozens of post-doctoral fellows who now occupy professorial chairs in the United States, Europe and Asia.

Last Updated July 2010

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