CONTENTS

INTRODUCTION

OVERVIEW OF EXTRAMURAL AIDS RESEARCH SUPPORTED BY NHLBI

Safety of the Nation's Blood Supply and Transplantable Tissue
Use of Blood Products to Treat HIV Infected Persons
HIV-1-Associated Lung Disease
HIV-1-Associated Blood Disease
HIV-1-Associated Cardiac Disease
Unraveling the Mechanisms of Infection

MINORITIES AND AIDS-RELATED RESEARCH

Tuberculosis and Minorities
Regulation of Granuloma in Tuberculosis
Pediatric Lung and Heart Complications of HIV Infection
Hyperimmune Globulin (HIVIG) in HIV-Infected Pregnant Women
Training and Career Enhancement Opportunities
Collaborative Projects on Minority Health: TB Program
Promoting Adherence to TB Regimens in Latino Adolescents

WOMEN AND AIDS-RELATED RESEARCH

Pulmonary and Cardiac Complications of Human Immunodeficiency Virus Infection
HIV-1 Hyperimmune Globulin (HIVIG) in HIV-1-Infected Pregnant Women

Transfusion Safety Study

CHILDREN AND AIDS-RELATED RESEARCH

Pediatric Pulmonary and Cardiovascular Complications of Human Immunodeficiency Virus Infection
HIV-1 Hyperimmune Globulin (HIVIG) in HIV-1-Infected Pregnant Women
HIV-1 Hyperimmune Globulin (HIVIG) in HIV-1-Infected Infants
Transfusion Safety Study
Cellular Infiltrative Disease of the Lung and HIV
Pediatric AIDS Foundation Study

NHLBI-INITIATED PROGRAMS RELATED TO AIDS

Fiscal Year 1998
Endothelial Dysfunction in HIV Infection

Fiscal Year 1997
Etiology of Cardiovascular Complications in HIV Infection (HL-96-017)

Fiscal Year 1996
Mechanisms of Activation of Human Immunodeficiency Virus (HIV) in the Lung
Viral Nucleic Acid Testing for HIV and Hepatitis C (HCV) in DonatedBlood
Viral Nucleic Acid Testing for HIV and Hepatitis C (HCV) in Organs for Transplantation

Fiscal Year 1995
Trial to Determine If Viral Activation Is Associated with Transfusion
          in Individuals Infected with HIV-1
HIV and Thrombotic Thrombocytopenic Purpura
Effects of Cytokines in AIDS Animal Models
Lung-Specific Drug Delivery Systems for Enhanced TB Treatment
Cell/Life Cycle Regulation in Microbial Pathogens of the Lung
Behavioral Interventions for Control of Tuberculosis

Fiscal Year 1994
Hematologic Consequences of HIV Infection of Marrow Cell
In vitro Inactivation of Viruses in Blood Components
Gene Therapy for Hemophiliacs A & B
HIV and Cellular Infiltrative Disease in the Lung
Hemoglobin-Based Oxygen Carriers: Mechanisms of Toxicity

Fiscal Year 1993
Expression of Tuberculosis in the Lung
Hyper-Immune Globulin (HIVIG) in HIV-1-Infected Pregnant Women
Tuberculosis Academic Award

Fiscal Year 1992
Kaposi's Sarcoma: Cell Cycle Studies of Vascular Cells
Development of Assay Systems for Screening Organ and Tissue Donors

Fiscal Year 1991
Pathobiology of P. carinii
Thrombocytopenic Purpura in HIV Infection
Retrovirus-induced Immune Platelet Abnormalities

Fiscal Year 1989
Epidemiologic Studies of Human Retroviruses in Volunteer Blood Donors:
         The NHLBI Retrovirus Epidemiology Blood Donor Study (REDS)
A Study of Pediatric Pulmonary and Cardiac Complications (P2C2) of
          Human Immunodeficiency Virus Infection

Fiscal Year 1988
Alveolar Macrophages and Defense of the Lung in AIDS

Fiscal Year 1987
Inactivation of Human Immuno-deficiency Virus (HIV-1) and Other
         Transfusion-Transmitted Viruses in Blood and Blood Components
Pathobiology of Bone Marrow Suppression in AIDS
Pulmonary Complications of HIV-1 Infection
AIDS-Associated Heart Disease

Fiscal Year 1986
Development and Evaluation of New Screening Tests for HIV-1 Antigens,
          Antibodies, or Nucleic Acids
Effectiveness of HIV-1 Antibody Screening
Maintenance of Chimpanzees for Hepatitis or AIDS Research
Maintenance of a Blood Specimen Repository

Fiscal Year 1985
AIDS Immune Globulin: A Pilot Study

Fiscal Year 1984
Specialized Centers of Research in Transfusion Medicine

Fiscal Year 1983
Transfusion Safety Study (formerly the Association of Blood Product Use
          with Immune Functions Study)

INVESTIGATOR-INITIATED RESEARCH RELATED TO AIDS

Blood Safety -- Grants Supported in Fiscal Year 1997 or Beyond
         SIV Infection Effect on Hematopoietic Stem Cells
          Novel Assays for Retroviruses in Blood and Donated Organs
Blood Safety -- Grants That Have Ended
          HIV Diversity/Pathogenesis in Donor-Recipient Clusters
          AIDS and Blood Donor Recruitment
          Preventing Transmission of Diseases--AIDS via Blood
          Novel Autologous Predeposit Blood Donation Program
          Aqueous Blood Substitute for Profound Hypothermia
          Blood Donations in the Elderly
          Mechanisms of Clotting Factor VIII Immunogenicity
          Immunoregulatory Defects in Hemophilia

Hematologic Complications -- Grants Supported in Fiscal Year 1997 or Beyond
          Studies of a Novel Tyrosine Kinase in Megakaryocyte
          Mechanisms of Hematopoiesis in AIDS
          Studies of a Related Adhesion Kinase in Megakaryocytes

Hematologic Complications -- Grants That Have Ended
          Effect of HIV on Hematopoietic and Stromal Marrow Cells
          Toxicity of Anti-AIDS on the Bone Marrow
          Hematopoietic Cell Function in AIDS
          Biochemistry, Physiology, and Immunology of Platelets
          Study of HIV Infection in Bone Marrow Stem Cells
          Mechanism of Hematopoietic Suppression in HIV-1 Infection

Pulmonary Complications -- Grants Supported in Fiscal Year 1997 or Beyond
          Surfactant Protein-D In Pneumocystis
          CC Chemokines and Human Cytomegalovirus Pneumonitis
          Macrophage Recruitment/Activation in Lung Defense
          Smoking and Respiratory Complications of HIV in Women
          Host Defense Against Intracellular Infection of the Lung

          Mechanisms of P. carinii Binding to Alveolar Epithelium
          Pulmonary Lymphocyte Apoptosis and Cell Cycle Arrest
          TNFA Receptor CD120A Induced Signaling in Macrophages
          Rapid Test System for Mycobacterial Susceptibility
          Oxidant Induced Beta Chemokines in Granuloma Formation

          Molecular Biology of P. carinii GP120
          Lung Macrophage Motility: Role of Fibronectin Receptors
          Regulation of Macrophage Interleukin-1 Beta Production
          HIV-Alveolar Macrophage Interaction
          Mechanism of INH and Rifampicin Resistance in TB

          Cytokines/Adhesion Molecules in TB Pathogenesis
          Genetics of Drug Resistance in Mycobaacterium tuberculosis
          Tuberculosis in a Multi-Ethnic Inner City Population
          Immunologic Analysis of Lymphocytic Alveolitis in AIDS
          HIV Infection and Expression in Alveolar Macrophages

          Mechanism of Action of Inhaled Pentamidine in AIDS
          Antimicrobial Function HIV-Infected Alveolar Macrophages
          Mechanisms of Pneumocystis carinii Pneumonia
          HIV-Induced Emphysema: A Challenge to Conventional Ideas

Pulmonary Complications -- Grants That Have Ended
          Mechanisms of Defective Natural Killer Cytotoxicity
          HIV Lung Disease and Macrophages -- Molecular Cell Biology
          Prospective Study of the Pulmonary Complications of HIV Infection (PACS)
          Pulmonary-Parasite Interactions--Pneumocystis

Cardiac Complications -- Grants Supported in Fiscal Year 1997 or Beyond
          Cardiotoxicity of Streptococcal Pyrogenic Exotoxins
Cardiac Complications -- Grants That Have Ended
          Cardiac Autonomic Control in Children of HIV-Positive Mothers

Transfusion-Transmitted AIDS -- Grants Supported in Fiscal Year 1997 or Beyond
          Immunoregulatory Defects in Hemophilia
          Transfusion-Transmitted AIDS -- Grants that Have Ended
          Hematology Analyzer System

INTRAMURAL AIDS RESEARCH SUPPORTED BY THE NHLBI

BIBLIOGRAPHY









Home





NHLBI/OD/arp98js/9-98





Please send us your feedback, comments, and questions
by using the appropriate link on the page, Contact the NHLBI.

Note to users of screen readers and other assistive technologies: please report your problems here.