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John F. Tisdale, M.D.


Principal Investigator thumbnail image

John F. Tisdale
Senior Investigator

P: +1 301 402 6497
F: +1 301 496 8396

Full Publications Listing

Successful Fertility Restoration After Allogeneic Hematopoietic Stem Cell Transplantation.
Gharwan H, Neary NM, Link M, Hsieh MM, Fitzhugh CD, Sherins RJ, Tisdale JF.
Endocr Pract. 2014 Jun 16:1-15.
[Text Abstract on PubMed]

Neurogenesis in the striatum of the adult human brain.
Ernst A, Alkass K, Bernard S, Salehpour M, Perl S, Tisdale J, Possnert G, Druid H, Frisén J.
Cell. 2014 Feb 27;156(5):1072-83.
[Text Abstract on PubMed]

Acquired haemophilia A after stem cell transplant for sickle cell disease: treatment with recombinant porcine factor VIII (OBI-1) and tolerance induction with rituximab/prednisone.
Lozier JN, Nghiem K, Lee M, Hodsdon B, Joe G, P Weitzel R, Tisdale JF, Hsieh M.
Haemophilia. 2014 Mar ;20(2):e185-8.
[Text Abstract on PubMed]

Evaluation of engraftment and immunological tolerance after reduced intensity conditioning in a rhesus hematopoietic stem cell gene therapy model.
Uchida N, Weitzel RP, Evans ME, Green R, Bonifacino AC, Krouse AE, Metzger ME, Hsieh MM, Donahue RE, Tisdale JF.
Gene Ther. 2014 Feb ;21(2):148-57.
[Text Abstract on PubMed]

TRIM5α variations influence transduction efficiency with lentiviral vectors in both human and rhesus CD34(+) cells in vitro and in vivo.
Evans ME, Kumkhaek C, Hsieh MM, Donahue RE, Tisdale JF, Uchida N.
Mol Ther. 2014 Feb ;22(2):348-58.
[Text Abstract on PubMed]

No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model.
Sellers SE, Dumitriu B, Morgan MJ, Hughes WM, Wu CO, Raghavarchari N, Yang Y, Uchida N, Tisdale JF, An DS, Chen IS, Hematti P, Donahue RE, Larochelle A, Young NS, Calado RT, Dunbar CE.
Mol Ther. 2014 Jan ;22(1):52-8.
[Text Abstract on PubMed]

Sirolimus and post transplant Cy synergistically maintain mixed chimerism in a mismatched murine model.
Fitzhugh CD, Weitzel RP, Hsieh MM, Phang OA, Madison C, Luznik L, Powell JD, Tisdale JF.
Bone Marrow Transplant..
[Text Abstract on PubMed]

MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway.
Kumkhaek C, Aerbajinai W, Liu W, Zhu J, Uchida N, Kurlander R, Hsieh MM, Tisdale JF, Rodgers GP.
Blood. 2013 Apr 18;121(16):3216-27.
[Text Abstract on PubMed]

Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34(+) Cells Correlates With In Vivo Vector Copy Number.
Uchida N, Evans ME, Hsieh MM, Bonifacino AC, Krouse AE, Metzger ME, Sellers SE, Dunbar CE, Donahue RE, Tisdale JF.
Mol Ther Nucleic Acids. 2013 01 ;2:e122.
[Text Abstract on PubMed]

Efficient transduction of human hematopoietic repopulating cells with a chimeric HIV1-based vector including SIV capsid.
Uchida N, Hsieh MM, Washington KN, Tisdale JF.
Exp Hematol. 2013 Sep ;41(9):779-788.e1.
[Text Abstract on PubMed]

Modeling tumor-host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy.
Herman SE, Sun X, McAuley EM, Hsieh MM, Pittaluga S, Raffeld M, Liu D, Keyvanfar K, Chapman CM, Chen J, Buggy JJ, Aue G, Tisdale JF, Pérez-Galán P, Wiestner A.
Leukemia. 2013 Dec ;27(12):2311-21.
[Text Abstract on PubMed]

HCT for nonmalignant disorders.
Tisdale JF, Eapen M, Saccardi R.
Biol Blood Marrow Transplant. 2013 Jan ;19(1 Suppl):S6-9.
[Text Abstract on PubMed]

Peripheral blood stem cell transplants do not result in endometrial stromal engraftment.
Wolff EF, Uchida N, Donahue RE, Metzger ME, Hsieh MM, Libfraind LL, Hill MJ, Tisdale JF.
Fertil. Steril. 2012 Oct 25.
[Text Abstract on PubMed]

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.
Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C, Schurman SH, Garabedian E, Kesserwan C, Jagadeesh GJ, Fu PY, Gschweng E, Cooper A, Tisdale JF, Weinberg KI, Crooks GM, Kapoor N, Shah A, Abdel-Azim H, Yu XJ, Smogorzewska M, Wayne AS, Rosenblatt HM, Davis CM, Hanson C, Rishi RG, Wang X, Gjertson D, Yang OO, Balamurugan A, Bauer G, Ireland JA, Engel BC, Podsakoff GM, Hershfield MS, Blaese RM, Parkman R, Kohn DB.
Blood. 2012 Nov 1;120(18):3635-46.
[Text Abstract on PubMed]

Infusion of hemolyzed red blood cells within peripheral blood stem cell grafts in patients with and without sickle cell disease.
Fitzhugh CD, Unno H, Hathaway V, Coles WA, Link ME, Weitzel RP, Zhao X, Wright EC, Stroncek DF, Kato GJ, Hsieh MM, Tisdale JF.
Blood. 2012 Jun 14;119(24):5671-3.
[Text Abstract on PubMed]

High-efficiency transduction of rhesus hematopoietic repopulating cells by a modified HIV1-based lentiviral vector.
Uchida N, Hargrove PW, Lap CJ, Evans ME, Phang O, Bonifacino AC, Krouse AE, Metzger ME, Nguyen AD, Hsieh MM, Wolfsberg TG, Donahue RE, Persons DA, Tisdale JF.
Mol Ther. 2012 Oct ;20(10):1882-92.
[Text Abstract on PubMed]

Human parvovirus B19 DNA replication induces a DNA damage response that is dispensable for cell cycle arrest at phase G2/M.
Lou S, Luo Y, Cheng F, Huang Q, Shen W, Kleiboeker S, Tisdale JF, Liu Z, Qiu J.
J Virol. 2012 Oct ;86(19):10748-58.
[Text Abstract on PubMed]

Allogeneic hematopoietic stem cell transplantation for sickle cell disease: the time is now.
Hsieh MM, Fitzhugh CD, Tisdale JF.
Blood. 2011 Aug 4;118(5):1197-207.
[Text Abstract on PubMed]

Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.
Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, Donahue RE, North TE.
Cell Stem Cell. 2011 Apr 8;8(4):445-58.
[Text Abstract on PubMed]

Accelerated lymphocyte reconstitution and long-term recovery after transplantation of lentiviral-transduced rhesus CD34+ cells mobilized by G-CSF and plerixafor.
Uchida N, Bonifacino A, Krouse AE, Metzger ME, Csako G, Lee-Stroka A, Fasano RM, Leitman SF, Mattapallil JJ, Hsieh MM, Tisdale JF, Donahue RE.
Exp Hematol. 2011 Jul ;39(7):795-805.
[Text Abstract on PubMed]

Optimal conditions for lentiviral transduction of engrafting human CD34+ cells.
Uchida N, Hsieh MM, Hayakawa J, Madison C, Washington KN, Tisdale JF.
Gene Ther. 2011 Nov ;18(11):1078-86.
[Text Abstract on PubMed]

In mixed hematopoietic chimerism, the donor red cells win.
Hsieh MM, Wu CJ, Tisdale JF.
Haematologica. 2011 Jan ;96(1):13-5.
[Text Abstract on PubMed]

Chicken HS4 insulators have minimal barrier function among progeny of human hematopoietic cells transduced with an HIV1-based lentiviral vector.
Uchida N, Washington KN, Lap CJ, Hsieh MM, Tisdale JF.
Mol Ther. 2011 Jan ;19(1):133-9.
[Text Abstract on PubMed]

Neutrophil count in African Americans: lowering the target cutoff to initiate or resume chemotherapy?
Hsieh MM, Tisdale JF, Rodgers GP, Young NS, Trimble EL, Little RF.
J. Clin. Oncol. 2010 Apr 1;28(10):1633-7.
[Text Abstract on PubMed]

The assessment of human erythroid output in NOD/SCID mice reconstituted with human hematopoietic stem cells.
Hayakawa J, Hsieh MM, Anderson DE, Phang O, Uchida N, Washington K, Tisdale JF.
Cell Transplant. 2010 01 ;19(11):1465-73.
[Text Abstract on PubMed]

Significant human beta-cell turnover is limited to the first three decades of life as determined by in vivo thymidine analog incorporation and radiocarbon dating.
Perl S, Kushner JA, Buchholz BA, Meeker AK, Stein GM, Hsieh M, Kirby M, Pechhold S, Liu EH, Harlan DM, Tisdale JF.
J Clin Endocrinol Metab. 2010 Oct ;95(10):E234-9.
[Text Abstract on PubMed]

5% dimethyl sulfoxide (DMSO) and pentastarch improves cryopreservation of cord blood cells over 10% DMSO.
Hayakawa J, Joyal EG, Gildner JF, Washington KN, Phang OA, Uchida N, Hsieh MM, Tisdale JF.
Transfusion. 2010 Oct ;50(10):2158-66.
[Text Abstract on PubMed]

Allogeneic hematopoietic stem-cell transplantation for sickle cell disease.
Hsieh MM, Kang EM, Fitzhugh CD, Link MB, Bolan CD, Kurlander R, Childs RW, Rodgers GP, Powell JD, Tisdale JF.
N. Engl. J. Med. 2009 Dec 10;361(24):2309-17.
[Text Abstract on PubMed]

Development of a human immunodeficiency virus type 1-based lentiviral vector that allows efficient transduction of both human and rhesus blood cells.
Uchida N, Washington KN, Hayakawa J, Hsieh MM, Bonifacino AC, Krouse AE, Metzger ME, Donahue RE, Tisdale JF.
J. Virol. 2009 Oct;83(19):9854-62.
[Text Abstract on PubMed]

Incidence of second cancers after allogeneic hematopoietic stem cell transplantation using reduced-dose radiation.
Hsieh MM, Fitzhugh CD, Tisdale JF.
Blood. 2009 Jul 2;114(1):225; author reply 225-6.
[Text Abstract on PubMed]

Transient in vivo beta-globin production after lentiviral gene transfer to hematopoietic stem cells in the nonhuman primate.
Hayakawa J, Ueda T, Lisowski L, Hsieh MM, Washington K, Phang O, Metzger M, Krouse A, Donahue RE, Sadelain M, Tisdale JF.
Hum. Gene Ther. 2009 Jun;20(6):563-72.
[Text Abstract on PubMed]

Granulocyte colony-stimulating factor (G-CSF) administration in individuals with sickle cell disease: time for a moratorium?
Fitzhugh CD, Hsieh MM, Bolan CD, Saenz C, Tisdale JF.
Cytotherapy. 2009;11(4):464-71.
[Text Abstract on PubMed]

Long-term vector integration site analysis following retroviral mediated gene transfer to hematopoietic stem cells for the treatment of HIV infection.
Hayakawa J, Washington K, Uchida N, Phang O, Kang EM, Hsieh MM, Tisdale JF.
PLoS One. 2009 01 ;4(1):e4211.
[Text Abstract on PubMed]

Busulfan produces efficient human cell engraftment in NOD/LtSz-Scid IL2Rgamma(null) mice.
Hayakawa J, Hsieh MM, Uchida N, Phang O, Tisdale JF.
Stem Cells. 2009 Jan ;27(1):175-82.
[Text Abstract on PubMed]

Donor demographic and laboratory predictors of allogeneic peripheral blood stem cell mobilization in an ethnically diverse population.
Vasu S, Leitman SF, Tisdale JF, Hsieh MM, Childs RW, Barrett AJ, Fowler DH, Bishop MR, Kang EM, Malech HL, Dunbar CE, Khuu HM, Wesley R, Yau YY, Bolan CD.
Blood. 2008 Sep 1;112(5):2092-100.
[Text Abstract on PubMed]

STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells.
Cohen PA, Koski GK, Czerniecki BJ, Bunting KD, Fu XY, Wang Z, Zhang WJ, Carter CS, Awad M, Distel CA, Nagem H, Paustian CC, Johnson TD, Tisdale JF, Shu S.
Blood. 2008 Sep 1;112(5):1832-43.
[Text Abstract on PubMed]

Transfusion-associated babesiosis with an atypical time course after nonmyeloablative transplantation for sickle cell disease.
Cirino CM, Leitman SF, Williams E, Fedorko D, Palmore TN, Klion A, Ockenhouse C, Fitzhugh C, Tisdale JF, Hsieh MM.
Ann. Intern. Med. 2008 May 20;148(10):794-5.
[Text Abstract on PubMed]

Sirolimus associated pneumonitis after nonmyeloablative peripheral blood stem cell transplant for sickle cell disease.
Hsieh MM, Link MB, Tisdale JF.
Biol. Blood Marrow Transplant. 2008 Feb;14(2):256-7.
[Text Abstract on PubMed]

HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques.
Hsieh MM, Linde NS, Wynter A, Metzger M, Wong C, Langsetmo I, Lin A, Smith R, Rodgers GP, Donahue RE, Klaus SJ, Tisdale JF.
Blood. 2007 Sep 15;110(6):2140-7.
[Text Abstract on PubMed]

Prevalence of neutropenia in the U.S. population: age, sex, smoking status, and ethnic differences.
Hsieh MM, Everhart JE, Byrd-Holt DD, Tisdale JF, Rodgers GP.
Ann Intern Med. 2007 Apr 3;146(7):486-92.
[Text Abstract on PubMed]

Low-dose parenteral busulfan provides an extended window for the infusion of hematopoietic stem cells in murine hosts.
Hsieh MM, Langemeijer S, Wynter A, Phang OA, Kang EM, Tisdale JF.
Exp Hematol. 2007 Sep ;35(9):1415-20.
[Text Abstract on PubMed]

Long-term effects of combination treatment with fludarabine and low-dose pulse cyclophosphamide in patients with lupus nephritis.
Illei GG, Yarboro CH, Kuroiwa T, Schlimgen R, Austin HA, Tisdale JF, Chitkara P, Fleisher T, Klippel JH, Balow JE, Boumpas DT.
Rheumatology (Oxford). 2007 Jun ;46(6):952-6.
[Text Abstract on PubMed]

How much insulin is enough? A quantitative assessment of the transdifferentiaton potential of liver.
Perl S, Hirshberg B, Harlan DM, Tisdale JF.
Diabetologia. 2007 Mar ;50(3):690-2.
[Text Abstract on PubMed]

Busulfan pharmacokinetics, toxicity, and low-dose conditioning for autologous transplantation of genetically modified hematopoietic stem cells in the rhesus macaque model.
Kang EM, Hsieh MM, Metzger M, Krouse A, Donahue RE, Sadelain M, Tisdale JF.
Exp Hematol. 2006 Feb ;34(2):132-9.
[Text Abstract on PubMed]

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference.
Samakoglu S, Lisowski L, Budak-Alpdogan T, Usachenko Y, Acuto S, Di Marzo R, Maggio A, Zhu P, Tisdale JF, Rivière I, Sadelain M.
Nat Biotechnol. 2006 Jan ;24(1):89-94.
[Text Abstract on PubMed]

Low-dose radiation plus rapamycin promotes long-term bone marrow chimerism.
Powell JD, Fitzhugh C, Kang EM, Hsieh M, Schwartz RH, Tisdale JF.
Transplantation. 2005 Dec 15;80(11):1541-5.
[Text Abstract on PubMed]

Side population cells derived from adult human liver generate hepatocyte-like cells in vitro.
Hussain SZ, Strom SC, Kirby MR, Burns S, Langemeijer S, Ueda T, Hsieh M, Tisdale JF.
Dig Dis Sci. 2005 Oct ;50(10):1755-63.
[Text Abstract on PubMed]

Hematopoietic stem cell transplantation prevents diabetes in NOD mice but does not contribute to significant islet cell regeneration once disease is established.
Kang EM, Zickler PP, Burns S, Langemeijer SM, Brenner S, Phang OA, Patterson N, Harlan D, Tisdale JF.
Exp Hematol. 2005 Jun ;33(6):699-705.
[Text Abstract on PubMed]

Cloning and functional analysis of the rhesus macaque ABCG2 gene. Forced expression confers an SP phenotype among hematopoietic stem cell progeny in vivo.
Ueda T, Brenner S, Malech HL, Langemeijer SM, Perl S, Kirby M, Phang OA, Krouse AE, Donahue RE, Kang EM, Tisdale JF.
J Biol Chem. 2005 Jan 14;280(2):991-8.
[Text Abstract on PubMed]

Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia.
Kiem HP, Sellers S, Thomasson B, Morris JC, Tisdale JF, Horn PA, Hematti P, Adler R, Kuramoto K, Calmels B, Bonifacino A, Hu J, von Kalle C, Schmidt M, Sorrentino B, Nienhuis A, Blau CA, Andrews RG, Donahue RE, Dunbar CE.
Mol. Ther. 2004 Mar;9(3):389-95.
[Text Abstract on PubMed]

The presence of the carboxy-terminal fragment of fibronectin allows maintenance of non-human primate long-term hematopoietic repopulating cells during extended ex vivo culture and transduction.
Sellers SE, Tisdale JF, Agricola BA, Donahue RE, Dunbar CE.
Exp. Hematol. 2004 Feb;32(2):163-70.
[Text Abstract on PubMed]

Comparison of retroviral transduction efficiency in CD34+ cells derived from bone marrow versus G-CSF-mobilized or G-CSF plus stem cell factor-mobilized peripheral blood in nonhuman primates.
Hematti P, Tuchman S, Larochelle A, Metzger ME, Donahue RE, Tisdale JF.
Stem Cells. 2004;22(6):1062-9.
[Text Abstract on PubMed]

Gene therapy for the hemoglobin disorders.
Persons DA, Tisdale JF.
Semin Hematol. 2004 Oct ;41(4):279-86.
[Text Abstract on PubMed]

The leukemogenic risk of integrating retroviral vectors in hematopoietic stem cell gene therapy applications.
Kang EM, Tisdale JF.
Curr Hematol Rep. 2004 Jul ;3(4):274-81.
[Text Abstract on PubMed]

Efficient characterization of retro-, lenti-, and foamyvector-transduced cell populations by high-accuracy insertion site sequencing.
Schmidt M, Glimm H, Wissler M, Hoffmann G, Olsson K, Sellers S, Carbonaro D, Tisdale JF, Leurs C, Hanenberg H, Dunbar CE, Kiem HP, Karlsson S, Kohn DB, Williams D, Von Kalle C.
Ann. N. Y. Acad. Sci. 2003 May;996:112-21.
[Text Abstract on PubMed]

Retrovirally transduced muscle-derived cells contribute to hematopoiesis at very low levels in the nonhuman primate model.
Gao C, Kang EM, Kuramoto K, Agricola BA, Metzger M, von Kalle C, Donahue RE, Tisdale JF.
Mol Ther. 2003 Dec ;8(6):974-80.
[Text Abstract on PubMed]

Transfusion-associated GVHD after fludarabine therapy in a patient with systemic lupus erythematosus.
Leitman SF, Tisdale JF, Bolan CD, Popovsky MA, Klippel JH, Balow JE, Boumpas DT, Illei GG.
Transfusion. 2003 Dec ;43(12):1667-71.
[Text Abstract on PubMed]

Clinical applications of gene therapy.
Tisdale JF, Wilson DR.
Curr Opin Mol Ther. 2003 Oct ;5(5):456-7.
[Text Abstract on PubMed]

Late complications following treatment for severe aplastic anemia (SAA) with high-dose cyclophosphamide (Cy): follow-up of a randomized trial.
Tisdale JF, Maciejewski JP, Nuñez O, Rosenfeld SJ, Young NS.
Blood. 2002 Dec 15;100(13):4668-70.
[Text Abstract on PubMed]

Polyclonal long-term repopulating stem cell clones in a primate model.
Schmidt M, Zickler P, Hoffmann G, Haas S, Wissler M, Muessig A, Tisdale JF, Kuramoto K, Andrews RG, Wu T, Kiem HP, Dunbar CE, von Kalle C.
Blood. 2002 Oct 15;100(8):2737-43.
[Text Abstract on PubMed]

High-dose cyclophosphamide for treatment of aplastic anemia.
Young NS, Tisdale JF.
Ann. Intern. Med. 2002 Sep 17;137(6):549-50; author reply 549-50.
[Text Abstract on PubMed]

Plasticity and hematopoiesis: Circe's transforming potion?
Tisdale JF, Dunbar CE.
Curr. Opin. Hematol. 2002 Jul;9(4):268-73.
[Text Abstract on PubMed]

Mobilization, collection, and processing of peripheral blood stem cells in individuals with sickle cell trait.
Kang EM, Areman EM, David-Ocampo V, Fitzhugh C, Link ME, Read EJ, Leitman SF, Rodgers GP, Tisdale JF.
Blood. 2002 Feb 1;99(3):850-5.
[Text Abstract on PubMed]

Clinical aspects of gene therapy.
Tisdale JF, Wilson DR.
Curr Opin Mol Ther. 2002 Oct ;4(5):417-8.
[Text Abstract on PubMed]

Gene therapy-based treatment for HIV-positive patients with malignancies.
Kang EM, De Witte M, Malech H, Morgan RA, Carter C, Leitman SF, Childs R, Barrett AJ, Little R, Tisdale JF.
J Hematother Stem Cell Res. 2002 Oct ;11(5):809-16.
[Text Abstract on PubMed]

Nonmyeloablative conditioning followed by transplantation of genetically modified HLA-matched peripheral blood progenitor cells for hematologic malignancies in patients with acquired immunodeficiency syndrome.
Kang EM, de Witte M, Malech H, Morgan RA, Phang S, Carter C, Leitman SF, Childs R, Barrett AJ, Little R, Tisdale JF.
Blood. 2002 Jan 15;99(2):698-701.
[Text Abstract on PubMed]

The effect of multidrug-resistance 1 gene versus neo transduction on ex vivo and in vivo expansion of rhesus macaque hematopoietic repopulating cells.
Sellers SE, Tisdale JF, Agricola BA, Metzger ME, Donahue RE, Dunbar CE, Sorrentino BP.
Blood. 2001 Mar 15;97(6):1888-91.
[Text Abstract on PubMed]

Persistent low-level engraftment of rhesus peripheral blood progenitor cells transduced with the fanconi anemia C gene after conditioning with low-dose irradiation.
Kang EM, Hanazano Y, Frare P, Vanin EF, De Witte M, Metzger M, Liu JM, Tisdale JF.
Mol Ther. 2001 Jun ;3(6):911-9.
[Text Abstract on PubMed]

The effects of SCF/G-CSF prestimulation on radiation sensitivity and engraftment in nonmyeloablated murine hosts.
Giri N, Kaushiva A, Wu T, Sellers SE, Tisdale JF.
Exp Hematol. 2001 Jun ;29(6):779-85.
[Text Abstract on PubMed]

Sino-orbital-cerebral aspergillosis in immunocompromised pediatric patients.
Robinson MR, Fine HF, Ross ML, Mont EK, Bryant-Greenwood PK, Hertle RW, Tisdale JF, Young NS, Zeichner SL, Van Waes C, Whitcup SM, Walsh TJ.
Pediatr. Infect. Dis. J. 2000 Dec;19(12):1197-203.
[Text Abstract on PubMed]

High-dose cyclophosphamide in severe aplastic anaemia: a randomised trial.
Tisdale JF, Dunn DE, Geller N, Plante M, Nunez O, Dunbar CE, Barrett AJ, Walsh TJ, Rosenfeld SJ, Young NS.
Lancet. 2000 Nov 4;356(9241):1554-9.
[Text Abstract on PubMed]

Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates.
Kim HJ, Tisdale JF, Wu T, Takatoku M, Sellers SE, Zickler P, Metzger ME, Agricola BA, Malley JD, Kato I, Donahue RE, Brown KE, Dunbar CE.
Blood. 2000 Jul 1;96(1):1-8.
[Text Abstract on PubMed]

Introduction of a xenogeneic gene via hematopoietic stem cells leads to specific tolerance in a rhesus monkey model.
Heim DA, Hanazono Y, Giri N, Wu T, Childs R, Sellers SE, Muul L, Agricola BA, Metzger ME, Donahue RE, Tisdale JF, Dunbar CE.
Mol. Ther. 2000 Jun;1(6):533-44.
[Text Abstract on PubMed]

Prolonged high-level detection of retrovirally marked hematopoietic cells in nonhuman primates after transduction of CD34+ progenitors using clinically feasible methods.
Wu T, Kim HJ, Sellers SE, Meade KE, Agricola BA, Metzger ME, Kato I, Donahue RE, Dunbar CE, Tisdale JF.
Mol. Ther. 2000 Mar;1(3):285-93.
[Text Abstract on PubMed]

Clinical and laboratory evidence for a trilineage haematopoietic defect in patients with refractory Diamond-Blackfan anaemia.
Giri N, Kang E, Tisdale JF, Follman D, Rivera M, Schwartz GN, Kim S, Young NS, Rick ME, Dunbar CE.
Br. J. Haematol. 2000 Jan;108(1):167-75.
[Text Abstract on PubMed]

Cyclophosphamide and other new agents for the treatment of severe aplastic anemia.
Tisdale JF, Dunn DE, Maciejewski J.
Semin Hematol. 2000 Jan ;37(1):102-9.
[Text Abstract on PubMed]

Retroviral marking and transplantation of rhesus hematopoietic cells by nonmyeloablative conditioning.
Huhn RD, Tisdale JF, Agricola B, Metzger ME, Donahue RE, Dunbar CE.
Hum. Gene Ther. 1999 Jul 20;10(11):1783-90.
[Text Abstract on PubMed]

No discrepancy between in vivo gene marking efficiency assessed in peripheral blood populations compared with bone marrow progenitors or CD34+ cells.
Sellers SE, Tisdale JF, Bodine DM, Williams DA, Karlsson S, Meztger M, Donahue RE, Dunbar CE.
Hum. Gene Ther. 1999 Mar 1;10(4):633-40.
[Text Abstract on PubMed]

Molecular and serological examination of the relationship of human herpesvirus 8 to multiple myeloma: orf 26 sequences in bone marrow stroma are not restricted to myeloma patients and other regions of the genome are not detected.
Tisdale JF, Stewart AK, Dickstein B, Little RF, Dubé I, Cappe D, Dunbar CE, Brown KE.
Blood. 1998 Oct 15;92(8):2681-7.
[Text Abstract on PubMed]

Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability.
Tisdale JF, Hanazono Y, Sellers SE, Agricola BA, Metzger ME, Donahue RE, Dunbar CE.
Blood. 1998 Aug 15;92(4):1131-41.
[Text Abstract on PubMed]

Murine bone marrow expressing the neomycin resistance gene has no competitive disadvantage assessed in vivo.
Wu T, Bloom ML, Yu JM, Tisdale JF, Dunbar CE.
Hum. Gene Ther. 1998 May 20;9(8):1157-64.
[Text Abstract on PubMed]

Severe thrombocytopenia in patients treated with suramin: evidence for an immune mechanism in one.
Tisdale JF, Figg WD, Reed E, McCall NA, Alkins BR, Horne MK 3rd.
Am J Hematol. 1996 Feb ;51(2):152-7.
[Text Abstract on PubMed]

Case report: poorly differentiated carcinoma of unknown primary presenting as Trousseau's syndrome.
Tisdale JF, Snowden TR, Johnson DR.
Am J Med Sci. 1995 Mar ;309(3):183-7.
[Text Abstract on PubMed]

Tisdale JF, Veldkamp P.
J Tenn Med Assoc. 1994 Nov ;87(11):480-1.
[Text Abstract on PubMed]

Agranulocytosis in a hyperthyroid patient.
Tisdale JF, Kemp WE.
J Tenn Med Assoc. 1994 Oct ;87(10):433-4.
[Text Abstract on PubMed]

Whipple's disease presenting with near fatal gastrointestinal bleeding.
Tisdale JF, Boland D.
J Tenn Med Assoc. 1994 Oct ;87(10):432-3.
[Text Abstract on PubMed]

Right leg swelling and weight loss in an elderly man.
Tisdale JF.
J Tenn Med Assoc. 1994 May ;87(5):196, 198.
[Text Abstract on PubMed]

Arthritis and chest pain in a young black woman.
Jirjis JN, Tisdale JF.
J Tenn Med Assoc. 1994 Apr ;87(4):153-4.
[Text Abstract on PubMed]

A subtle radiographic finding with fatal implications.
Tisdale JF, Veldkamp P.
J Tenn Med Assoc. 1994 Mar ;87(3):102-3.
[Text Abstract on PubMed]