Accessible Search Form           Advanced Search

James R. Sellers, Ph.D.

Publications


Principal Investigator thumbnail image

James R. Sellers
Senior Investigator

P: +1 301 496 6887
F: +1 301 402 1519
sellersj@nhlbi.nih.gov


Full Publications Listing

Enthalpies and entropies of adsorption on well-defined oxide surfaces: experimental measurements.
Campbell CT, Sellers JR.
Chem Rev. 2013 Jun 12;113(6):4106-35.
[Text Abstract on PubMed]

Loss of actomyosin regulation in distal arthrogryposis myopathy due to mutant myosin binding protein-C slow.
Ackermann MA, Patel PD, Valenti J, Takagi Y, Homsher E, Sellers JR, Kontrogianni-Konstantopoulos A.
FASEB J. 2013 May 21.
[Text Abstract on PubMed]

Myosin Regulatory Light Chain (RLC) Phosphorylation Change as a Modulator of Cardiac Muscle Contraction in Disease.
Toepfer C, Caorsi V, Kampourakis T, Sikkel MB, West TG, Leung MC, Al-Saud SA, Macleod KT, Lyon AR, Marston SB, Sellers JR, Ferenczi MA.
J Biol Chem. 2013 May 10;288(19):13446-54.
[Text Abstract on PubMed]

Mammalian myosin-18A, a highly divergent myosin.
Guzik-Lendrum S, Heissler SM, Billington N, Takagi Y, Yang Y, Knight PJ, Homsher E, Sellers JR.
J Biol Chem. 2013 Mar 29;288(13):9532-48.
[Text Abstract on PubMed]

A subdomain interaction at the base of the lever allosterically tunes the mechanochemical mechanism of myosin 5a.
Nagy NT, Chakraborty S, Harami GM, Sellers JR, Sakamoto T, Kovács M.
PLoS One. 2013 01 ;8(5):e62640.
[Text Abstract on PubMed]

Kinetic characterization of nonmuscle myosin IIb at the single molecule level.
Nagy A, Takagi Y, Billington N, Sun SA, Hong DK, Homsher E, Wang A, Sellers JR.
J Biol Chem. 2013 Jan 4;288(1):709-22.
[Text Abstract on PubMed]

Temperature dependent measurements reveal similarities between muscle and non-muscle myosin motility.
Yengo CM, Takagi Y, Sellers JR.
J. Muscle Res. Cell. Motil. 2012 Dec;33(6):385-94.
[Text Abstract on PubMed]

Dynamic Exchange of Myosin VI on Endocytic Structures.
Bond LM, Arden SD, Kendrick-Jones J, Buss F, Sellers JR.
J. Biol. Chem. 2012 Nov 9;287(46):38637-46.
[Text Abstract on PubMed]

The entropies of adsorbed molecules.
Campbell CT, Sellers JR.
J Am Chem Soc. 2012 Oct 31;134(43):18109-15.
[Text Abstract on PubMed]

Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis.
Ma X, Kovács M, Conti MA, Wang A, Zhang Y, Sellers JR, Adelstein RS.
Proc. Natl. Acad. Sci. U.S.A. 2012 Mar 20;109(12):4509-14.
[Text Abstract on PubMed]

Walking to work: roles for class V myosins as cargo transporters.
Hammer, Sellers JR.
Nat. Rev. Mol. Cell Biol. 2012 Jan;13(1):13-26.
[Text Abstract on PubMed]

Myosin motor proteins are involved in the final stages of the secretory pathways.
Bond LM, Brandstaetter H, Sellers JR, Kendrick-Jones J, Buss F.
Biochem. Soc. Trans. 2011 Oct;39(5):1115-9.
[Text Abstract on PubMed]

Regulation of myosin 5a and myosin 7a.
Siththanandan VB, Sellers JR.
Biochem. Soc. Trans. 2011 Oct;39(5):1136-41.
[Text Abstract on PubMed]

Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination.
Pécsi I, Szabó JE, Adams SD, Simon I, Sellers JR, Vértessy BG, Tóth J.
Proc. Natl. Acad. Sci. U.S.A. 2011 Aug 30;108(35):14437-42.
[Text Abstract on PubMed]

Drosophila melanogaster myosin-18 represents a highly divergent motor with actin tethering properties.
Guzik-Lendrum S, Nagy A, Takagi Y, Houdusse A, Sellers JR.
J. Biol. Chem. 2011 Jun 17;286(24):21755-66.
[Text Abstract on PubMed]

Light-triggered myosin activation for probing dynamic cellular processes.
Goguen BN, Hoffman BD, Sellers JR, Schwartz MA, Imperiali B.
Angew. Chem. Int. Ed. Engl. 2011 Jun 14;50(25):5667-70.
[Text Abstract on PubMed]

Dynein struts its stuff.
Billington N, Sellers JR.
Nat. Struct. Mol. Biol. 2011 Jun;18(6):635-6.
[Text Abstract on PubMed]

The kinetic mechanism of mouse myosin VIIA.
Haithcock J, Billington N, Choi K, Fordham J, Sellers JR, Stafford WF, White H, Forgacs E.
J. Biol. Chem. 2011 Mar 18;286(11):8819-28.
[Text Abstract on PubMed]

Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.
Bond LM, Peden AA, Kendrick-Jones J, Sellers JR, Buss F.
Mol. Biol. Cell. 2011 Jan 1;22(1):54-65.
[Text Abstract on PubMed]

Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5.
Nagy NT, Sakamoto T, Takács B, Gyimesi M, Hazai E, Bikádi Z, Sellers JR, Kovács M.
FASEB J. 2010 Nov;24(11):4480-90.
[Text Abstract on PubMed]

Nonmuscle myosin IIA with a GFP fused to the N-terminus of the regulatory light chain is regulated normally.
Kengyel A, Wolf WA, Chisholm RL, Sellers JR.
J. Muscle Res. Cell. Motil. 2010 Sep;31(3):163-70.
[Text Abstract on PubMed]

Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing.
Kitajiri S, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I, Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J, Bartles JR, Hammer, Richardson GP, Griffith AJ, Frolenkov GI, Friedman TB.
Cell. 2010 May 28;141(5):786-98.
[Text Abstract on PubMed]

Direct observation of the myosin-Va power stroke and its reversal.
Sellers JR, Veigel C.
Nat. Struct. Mol. Biol. 2010 May;17(5):590-5.
[Text Abstract on PubMed]

Influence of lever structure on myosin 5a walking.
Oke OA, Burgess SA, Forgacs E, Knight PJ, Sakamoto T, Sellers JR, White H, Trinick J.
Proc. Natl. Acad. Sci. U.S.A. 2010 Feb 9;107(6):2509-14.
[Text Abstract on PubMed]

The SAH domain extends the functional length of the myosin lever.
Baboolal TG, Sakamoto T, Forgacs E, White HD, Jackson SM, Takagi Y, Farrow RE, Molloy JE, Knight PJ, Sellers JR, Peckham M.
Proc. Natl. Acad. Sci. U.S.A. 2009 Dec 29;106(52):22193-8.
[Text Abstract on PubMed]

Extensibility of the extended tail domain of processive and nonprocessive myosin V molecules.
Nagy A, Piszczek G, Sellers JR.
Biophys. J. 2009 Dec 16;97(12):3123-31.
[Text Abstract on PubMed]

An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation.
Jana SS, Kim KY, Mao J, Kawamoto S, Sellers JR, Adelstein RS.
J. Biol. Chem. 2009 Apr 24;284(17):11563-71.
[Text Abstract on PubMed]

A FERM domain autoregulates Drosophila myosin 7a activity.
Yang Y, Baboolal TG, Siththanandan V, Chen M, Walker ML, Knight PJ, Peckham M, Sellers JR.
Proc. Natl. Acad. Sci. U.S.A. 2009 Mar 17;106(11):4189-94.
[Text Abstract on PubMed]

Direct observation of the mechanochemical coupling in myosin Va during processive movement.
Sakamoto T, Webb MR, Forgacs E, White HD, Sellers JR.
Nature. 2008 Sep 4;455(7209):128-32.
[Text Abstract on PubMed]

Load-dependent mechanism of nonmuscle myosin 2.
Kovács M, Thirumurugan K, Knight PJ, Sellers JR.
Proc. Natl. Acad. Sci. U.S.A. 2007 Jun 12;104(24):9994-9.
[Text Abstract on PubMed]

Diversity of structural behavior in vertebrate conventional myosins complexed with actin.
Iwamoto H, Oiwa K, Kovács M, Sellers JR, Suzuki T, Wakayama J, Tamura T, Yagi N, Fujisawa T.
J. Mol. Biol. 2007 May 25;369(1):249-64.
[Text Abstract on PubMed]

Loop 2 of limulus myosin III is phosphorylated by protein kinase A and autophosphorylation.
Kempler K, Tóth J, Yamashita R, Mapel G, Robinson K, Cardasis H, Stevens S, Sellers JR, Battelle BA.
Biochemistry. 2007 Apr 10;46(14):4280-93.
[Text Abstract on PubMed]

Kinetic mechanism of myosinV-S1 using a new fluorescent ATP analogue.
Forgacs E, Cartwright S, Kovács M, Sakamoto T, Sellers JR, Corrie JE, Webb MR, White HD.
Biochemistry. 2006 Oct 31;45(43):13035-45.
[Text Abstract on PubMed]

In vitro reconstitution of a transport complex containing Rab27a, melanophilin and myosin Va.
Wu X, Sakamoto T, Zhang F, Sellers JR, Hammer.
FEBS Lett. 2006 Oct 30;580(25):5863-8.
[Text Abstract on PubMed]

The cargo-binding domain regulates structure and activity of myosin 5.
Thirumurugan K, Sakamoto T, Hammer, Sellers JR, Knight PJ.
Nature. 2006 Jul 13;442(7099):212-5.
[Text Abstract on PubMed]

Dimerized Drosophila myosin VIIa: a processive motor.
Yang Y, Kovács M, Sakamoto T, Zhang F, Kiehart DP, Sellers JR.
Proc. Natl. Acad. Sci. U.S.A. 2006 Apr 11;103(15):5746-51.
[Text Abstract on PubMed]

Walking with myosin V.
Sellers JR, Veigel C.
Curr. Opin. Cell Biol. 2006 Feb;18(1):68-73.
[Text Abstract on PubMed]

Step-size is determined by neck length in myosin V.
Sakamoto T, Yildez A, Selvin PR, Sellers JR.
Biochemistry. 2005 Dec 13;44(49):16203-10.
[Text Abstract on PubMed]

The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head.
Knight PJ, Thirumurugan K, Xu Y, Wang F, Kalverda AP, Stafford, Sellers JR, Peckham M.
J. Biol. Chem. 2005 Oct 14;280(41):34702-8.
[Text Abstract on PubMed]

Drosophila myosin V is required for larval development and spermatid individualization.
Mermall V, Bonafé N, Jones L, Sellers JR, Cooley L, Mooseker MS.
Dev. Biol. 2005 Oct 1;286(1):238-55.
[Text Abstract on PubMed]

Myosin VIIB from Drosophila is a high duty ratio motor.
Yang Y, Kovács M, Xu Q, Anderson JB, Sellers JR.
J. Biol. Chem. 2005 Sep 16;280(37):32061-8.
[Text Abstract on PubMed]

Load-dependent kinetics of myosin-V can explain its high processivity.
Veigel C, Schmitz S, Wang F, Sellers JR.
Nat. Cell Biol. 2005 Sep;7(9):861-9.
[Text Abstract on PubMed]

Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family.
Tóth J, Kovács M, Wang F, Nyitray L, Sellers JR.
J. Biol. Chem. 2005 Aug 26;280(34):30594-603.
[Text Abstract on PubMed]

Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C.
Kim KY, Kovács M, Kawamoto S, Sellers JR, Adelstein RS.
J. Biol. Chem. 2005 Jun 17;280(24):22769-75.
[Text Abstract on PubMed]

Mechanism of action of myosin X, a membrane-associated molecular motor.
Kovács M, Wang F, Sellers JR.
J. Biol. Chem. 2005 Apr 15;280(15):15071-83.
[Text Abstract on PubMed]

Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia.
Belyantseva IA, Boger ET, Naz S, Frolenkov GI, Sellers JR, Ahmed ZM, Griffith AJ, Friedman TB.
Nat. Cell Biol. 2005 Feb;7(2):148-56.
[Text Abstract on PubMed]

Blebbistatin, a myosin II inhibitor, is photoinactivated by blue light.
Sakamoto T, Limouze J, Combs CA, Straight AF, Sellers JR.
Biochemistry. 2005 Jan 18;44(2):584-8.
[Text Abstract on PubMed]

Nanometer localization of single green fluorescent proteins: evidence that myosin V walks hand-over-hand via telemark configuration.
Snyder GE, Sakamoto T, Hammer, Sellers JR, Selvin PR.
Biophys. J. 2004 Sep;87(3):1776-83.
[Text Abstract on PubMed]

Mechanism of blebbistatin inhibition of myosin II.
Kovács M, Tóth J, Hetényi C, Málnási-Csizmadia A, Sellers JR.
J. Biol. Chem. 2004 Aug 20;279(34):35557-63.
[Text Abstract on PubMed]

Actin-dependent motility of melanosomes from fish retinal pigment epithelial (RPE) cells investigated using in vitro motility assays.
McNeil EL, Tacelosky D, Basciano P, Biallas B, Williams R, Damiani P, Deacon S, Fox C, Stewart B, Petruzzi N, Osborn C, Klinger K, Sellers JR, Smith CK.
Cell Motil. Cytoskeleton. 2004 Jun;58(2):71-82.
[Text Abstract on PubMed]

Two-headed binding of the unphosphorylated nonmuscle heavy meromyosin.ADP complex to actin.
Kovács M, Tóth J, Nyitray L, Sellers JR.
Biochemistry. 2004 Apr 13;43(14):4219-26.
[Text Abstract on PubMed]

Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family.
Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS.
J. Biol. Chem. 2004 Jan 23;279(4):2800-8.
[Text Abstract on PubMed]

Regulated conformation of myosin V.
Wang F, Thirumurugan K, Stafford WF, Hammer, Knight PJ, Sellers JR.
J. Biol. Chem. 2004 Jan 23;279(4):2333-6.
[Text Abstract on PubMed]

Specificity of blebbistatin, an inhibitor of myosin II.
Limouze J, Straight AF, Mitchison T, Sellers JR.
J. Muscle Res. Cell. Motil. 2004;25(4-5):337-41.
[Text Abstract on PubMed]

Fifty years of contractility research post sliding filament hypothesis.
Sellers JR.
J. Muscle Res. Cell. Motil. 2004;25(6):475-82.
[Text Abstract on PubMed]

Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform.
Kovács M, Wang F, Hu A, Zhang Y, Sellers JR.
J. Biol. Chem. 2003 Oct 3;278(40):38132-40.
[Text Abstract on PubMed]

Neck length and processivity of myosin V.
Sakamoto T, Wang F, Schmitz S, Xu Y, Xu Q, Molloy JE, Veigel C, Sellers JR.
J. Biol. Chem. 2003 Aug 1;278(31):29201-7.
[Text Abstract on PubMed]

Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance.
Wang F, Kovacs M, Hu A, Limouze J, Harvey EV, Sellers JR.
J. Biol. Chem. 2003 Jul 25;278(30):27439-48.
[Text Abstract on PubMed]

Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor.
Straight AF, Cheung A, Limouze J, Chen I, Westwood NJ, Sellers JR, Mitchison TJ.
Science. 2003 Mar 14;299(5613):1743-7.
[Text Abstract on PubMed]

Utility of genetic screening in hypertrophic cardiomyopathy: prevalence and significance of novel and double (homozygous and heterozygous) beta-myosin mutations.
Mohiddin SA, Begley DA, McLam E, Cardoso JP, Winkler JB, Sellers JR, Fananapazir L.
Genet. Test. 2003 Spring;7(1):21-7.
[Text Abstract on PubMed]

Trifluoperazine inhibits the MgATPase activity and in vitro motility of conventional and unconventional myosins.
Sellers JR, Wang F, Chantler PD.
J. Muscle Res. Cell. Motil. 2003;24(8):579-85.
[Text Abstract on PubMed]

The prepower stroke conformation of myosin V.
Burgess S, Walker M, Wang F, Sellers JR, White HD, Knight PJ, Trinick J.
J. Cell Biol. 2002 Dec 23;159(6):983-91.
[Text Abstract on PubMed]

Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function.
Hu A, Wang F, Sellers JR.
J. Biol. Chem. 2002 Nov 29;277(48):46512-7.
[Text Abstract on PubMed]

Rab27a is an essential component of melanosome receptor for myosin Va.
Wu X, Wang F, Rao K, Sellers JR, Hammer.
Mol. Biol. Cell. 2002 May;13(5):1735-49.
[Text Abstract on PubMed]

Identification of an organelle receptor for myosin-Va.
Wu XS, Rao K, Zhang H, Wang F, Sellers JR, Matesic LE, Copeland NG, Jenkins NA, Hammer.
Nat. Cell Biol. 2002 Apr;4(4):271-8.
[Text Abstract on PubMed]

The gated gait of the processive molecular motor, myosin V.
Veigel C, Wang F, Bartoo ML, Sellers JR, Molloy JE.
Nat. Cell Biol. 2002 Jan;4(1):59-65.
[Text Abstract on PubMed]

Smooth muscle myosin filament assembly under control of a kinase-related protein (KRP) and caldesmon.
Kudryashov DS, Vorotnikov AV, Dudnakova TV, Stepanova OV, Lukas TJ, Sellers JR, Watterson DM, Shirinsky VP.
J. Muscle Res. Cell. Motil. 2002;23(4):341-51.
[Text Abstract on PubMed]

Myosin-I nomenclature.
Gillespie PG, Albanesi JP, Bahler M, Bement WM, Berg JS, Burgess DR, Burnside B, Cheney RE, Corey DP, Coudrier E, de Lanerolle P, Hammer JA, Hasson T, Holt JR, Hudspeth AJ, Ikebe M, Kendrick-Jones J, Korn ED, Li R, Mercer JA, Milligan RA, Mooseker MS, Ostap EM, Petit C, Pollard TD, Sellers JR, Soldati T, Titus MA.
J. Cell Biol. 2001 Nov 26;155(5):703-4.
[Text Abstract on PubMed]

Phosphorylation-dependent regulation is absent in a nonmuscle heavy meromyosin construct with one complete head and one head lacking the motor domain.
Cremo CR, Wang F, Facemyer K, Sellers JR.
J. Biol. Chem. 2001 Nov 2;276(44):41465-72.
[Text Abstract on PubMed]

Human myosin XVBP is a transcribed pseudogene.
Boger ET, Sellers JR, Friedman TB.
J. Muscle Res. Cell. Motil. 2001;22(5):477-83.
[Text Abstract on PubMed]

Two-headed binding of a processive myosin to F-actin.
Walker ML, Burgess SA, Sellers JR, Wang F, Hammer, Trinick J, Knight PJ.
Nature. 2000 Jun 15;405(6788):804-7.
[Text Abstract on PubMed]

Kinetics of smooth muscle heavy meromyosin with one thiophosphorylated head.
Ellison PA, Sellers JR, Cremo CR.
J. Biol. Chem. 2000 May 19;275(20):15142-51.
[Text Abstract on PubMed]

A conserved negatively charged amino acid modulates function in human nonmuscle myosin IIA.
Wang F, Harvey EV, Conti MA, Wei D, Sellers JR.
Biochemistry. 2000 May 9;39(18):5555-60.
[Text Abstract on PubMed]

Myosins: a diverse superfamily.
Sellers JR.
Biochim. Biophys. Acta. 2000 Mar 17;1496(1):3-22.
[Text Abstract on PubMed]

Effect of ADP and ionic strength on the kinetic and motile properties of recombinant mouse myosin V.
Wang F, Chen L, Arcucci O, Harvey EV, Bowers B, Xu Y, Hammer, Sellers JR.
J. Biol. Chem. 2000 Feb 11;275(6):4329-35.
[Text Abstract on PubMed]

Identification and analysis of the myosin superfamily in Drosophila: a database approach.
Yamashita RA, Sellers JR, Anderson JB.
J. Muscle Res. Cell. Motil. 2000;21(6):491-505.
[Text Abstract on PubMed]

Unique sequence of a high molecular weight myosin light chain kinase is involved in interaction with actin cytoskeleton.
Kudryashov DS, Chibalina MV, Birukov KG, Lukas TJ, Sellers JR, Van Eldik LJ, Watterson DM, Shirinsky VP.
FEBS Lett. 1999 Dec 10;463(1-2):67-71.
[Text Abstract on PubMed]

Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2.
Liang Y, Wang A, Belyantseva IA, Anderson DW, Probst FJ, Barber TD, Miller W, Touchman JW, Jin L, Sullivan SL, Sellers JR, Camper SA, Lloyd RV, Kachar B, Friedman TB, Fridell RA.
Genomics. 1999 Nov 1;61(3):243-58.
[Text Abstract on PubMed]

Unconventional myosins and the genetics of hearing loss.
Friedman TB, Sellers JR, Avraham KB.
Am. J. Med. Genet. 1999 Sep 24;89(3):147-57.
[Text Abstract on PubMed]

Unphosphorylated crossbridges and latch: smooth muscle regulation revisited.
Sellers JR.
J. Muscle Res. Cell. Motil. 1999 May;20(4):347-9.
[Text Abstract on PubMed]

Analysis of the regulatory phosphorylation site in Acanthamoeba myosin IC by using site-directed mutagenesis.
Wang ZY, Wang F, Sellers JR, Korn ED, Hammer.
Proc. Natl. Acad. Sci. U.S.A. 1998 Dec 22;95(26):15200-5.
[Text Abstract on PubMed]

A myosin III from Limulus eyes is a clock-regulated phosphoprotein.
Battelle BA, Andrews AW, Calman BG, Sellers JR, Greenberg RM, Smith WC.
J. Neurosci. 1998 Jun 15;18(12):4548-59.
[Text Abstract on PubMed]

Tyrosine phosphorylation of the beta3 cytoplasmic domain mediates integrin-cytoskeletal interactions.
Jenkins AL, Nannizzi-Alaimo L, Silver D, Sellers JR, Ginsberg MH, Law DA, Phillips DR.
J. Biol. Chem. 1998 May 29;273(22):13878-85.
[Text Abstract on PubMed]

Kinetic tuning of myosin via a flexible loop adjacent to the nucleotide binding pocket.
Sweeney HL, Rosenfeld SS, Brown F, Faust L, Smith J, Xing J, Stein LA, Sellers JR.
J. Biol. Chem. 1998 Mar 13;273(11):6262-70.
[Text Abstract on PubMed]

Molecular characterization of myosin V from Drosophila melanogaster.
Bonafé N, Sellers JR.
J. Muscle Res. Cell. Motil. 1998 Feb;19(2):129-41.
[Text Abstract on PubMed]

Motility assays on molluscan native thick filaments.
Han YJ, Sellers JR.
Meth. Enzymol. 1998;298:427-35.
[Text Abstract on PubMed]

Effect of Mts1 on the structure and activity of nonmuscle myosin II.
Ford HL, Silver DL, Kachar B, Sellers JR, Zain SB.
Biochemistry. 1997 Dec 23;36(51):16321-7.
[Text Abstract on PubMed]

Sites of interaction between kinase-related protein and smooth muscle myosin.
Silver DL, Vorotnikov AV, Watterson DM, Shirinsky VP, Sellers JR.
J. Biol. Chem. 1997 Oct 3;272(40):25353-9.
[Text Abstract on PubMed]

The in vitro motility activity of beta-cardiac myosin depends on the nature of the beta-myosin heavy chain gene mutation in hypertrophic cardiomyopathy.
Cuda G, Fananapazir L, Epstein ND, Sellers JR.
J. Muscle Res. Cell. Motil. 1997 Jun;18(3):275-83.
[Text Abstract on PubMed]

The amino acid sequence of the light chain of Acanthamoeba myosin IC.
Wang ZY, Sakai J, Matsudaira PT, Baines IC, Sellers JR, Hammer, Korn ED.
J. Muscle Res. Cell. Motil. 1997 Jun;18(3):395-8.
[Text Abstract on PubMed]

Inhibition of myocardial crossbridge cycling by hypoxic endothelial cells: a potential mechanism for matching oxygen supply and demand?
Shah AM, Mebazaa A, Yang ZK, Cuda G, Lankford EB, Pepper CB, Sollott SJ, Sellers JR, Robotham JL, Lakatta EG.
Circ. Res. 1997 May;80(5):688-98.
[Text Abstract on PubMed]

In vitro actin filament sliding velocities produced by mixtures of different types of myosin.
Cuda G, Pate E, Cooke R, Sellers JR.
Biophys. J. 1997 Apr;72(4):1767-79.
[Text Abstract on PubMed]

Phosphorylation of calponin in airway smooth muscle.
Pohl J, Winder SJ, Allen BG, Walsh MP, Sellers JR, Gerthoffer WT.
Am. J. Physiol. 1997 Jan;272(1 Pt 1):L115-23.
[Text Abstract on PubMed]

Activation of MAP kinases and phosphorylation of caldesmon in canine colonic smooth muscle.
Gerthoffer WT, Yamboliev IA, Shearer M, Pohl J, Haynes R, Dang S, Sato K, Sellers JR.
J. Physiol. (Lond.). 1996 Sep 15;495 ( Pt 3):597-609.
[Text Abstract on PubMed]

Structure and function of the 10 S conformation of smooth muscle myosin.
Olney JJ, Sellers JR, Cremo CR.
J. Biol. Chem. 1996 Aug 23;271(34):20375-84.
[Text Abstract on PubMed]

Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities.
Kelley CA, Sellers JR, Gard DL, Bui D, Adelstein RS, Baines IC.
J. Cell Biol. 1996 Aug;134(3):675-87.
[Text Abstract on PubMed]

Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle.
Poetter K, Jiang H, Hassanzadeh S, Master SR, Chang A, Dalakas MC, Rayment I, Sellers JR, Fananapazir L, Epstein ND.
Nat. Genet. 1996 May;13(1):63-9.
[Text Abstract on PubMed]

Kinesin and NCD, two structural cousins of myosin.
Sellers JR.
J. Muscle Res. Cell. Motil. 1996 Apr;17(2):173-5.
[Text Abstract on PubMed]

Baculovirus expression of chicken nonmuscle heavy meromyosin II-B. Characterization of alternatively spliced isoforms.
Pato MD, Sellers JR, Preston YA, Harvey EV, Adelstein RS.
J. Biol. Chem. 1996 Feb 2;271(5):2689-95.
[Text Abstract on PubMed]

A myosin family reunion.
Sellers JR, Goodson HV, Wang F.
J. Muscle Res. Cell. Motil. 1996 Feb;17(1):7-22.
[Text Abstract on PubMed]

Structural interpretation of the mutations in the beta-cardiac myosin that have been implicated in familial hypertrophic cardiomyopathy.
Rayment I, Holden HM, Sellers JR, Fananapazir L, Epstein ND.
Proc. Natl. Acad. Sci. U.S.A. 1995 Apr 25;92(9):3864-8.
[Text Abstract on PubMed]

Two heads are required for phosphorylation-dependent regulation of smooth muscle myosin.
Facemyer KC, Sellers JR, Cremo CR.
Biophys. J. 1995 Apr;68(4 Suppl):228S.
[Text Abstract on PubMed]

Two heads are required for phosphorylation-dependent regulation of smooth muscle myosin.
Cremo CR, Sellers JR, Facemyer KC.
J. Biol. Chem. 1995 Feb 3;270(5):2171-5.
[Text Abstract on PubMed]

Motor proteins 2: myosin.
Sellers JR, Goodson HV.
Protein Profile. 1995;2(12):1323-1423.
[Text Abstract on PubMed]

A kinase-related protein stabilizes unphosphorylated smooth muscle myosin minifilaments in the presence of ATP.
Shirinsky VP, Vorotnikov AV, Birukov KG, Nanaev AK, Collinge M, Lukas TJ, Sellers JR, Watterson DM.
J. Biol. Chem. 1993 Aug 5;268(22):16578-83.
[Text Abstract on PubMed]

Skeletal muscle expression and abnormal function of beta-myosin in hypertrophic cardiomyopathy.
Cuda G, Fananapazir L, Zhu WS, Sellers JR, Epstein ND.
J. Clin. Invest. 1993 Jun;91(6):2861-5.
[Text Abstract on PubMed]

Regulation of actomyosin interactions in Limulus muscle proteins.
Wang F, Martin BM, Sellers JR.
J. Biol. Chem. 1993 Feb 15;268(5):3776-80.
[Text Abstract on PubMed]

In vitro studies of determinants of smooth muscle mechanics.
Sellers JR, Umemoto S, Cuda G.
Adv. Exp. Med. Biol. 1993;332:267-76; discussion 276-7.
[Text Abstract on PubMed]

Myosin-specific adaptations of the motility assay.
Sellers JR, Cuda G, Wang F, Homsher E.
Methods Cell Biol. 1993;39:23-49.
[Text Abstract on PubMed]

In vitro functional characterization of bacterially expressed human fibroblast tropomyosin isoforms and their chimeric mutants.
Novy RE, Sellers JR, Liu LF, Lin JJ.
Cell Motil. Cytoskeleton. 1993;26(3):248-61.
[Text Abstract on PubMed]

Inhibition of the relative movement of actin and myosin by caldesmon and calponin.
Shirinsky VP, Biryukov KG, Hettasch JM, Sellers JR.
J. Biol. Chem. 1992 Aug 5;267(22):15886-92.
[Text Abstract on PubMed]

Factors affecting movement of F-actin filaments propelled by skeletal muscle heavy meromyosin.
Homsher E, Wang F, Sellers JR.
Am. J. Physiol. 1992 Mar;262(3 Pt 1):C714-23.
[Text Abstract on PubMed]

Smooth muscle myosin is composed of homodimeric heavy chains.
Kelley CA, Sellers JR, Goldsmith PK, Adelstein RS.
J. Biol. Chem. 1992 Feb 5;267(4):2127-30.
[Text Abstract on PubMed]

Purification and characterization of platelet myosin.
Daniel JL, Sellers JR.
Meth. Enzymol. 1992;215:78-88.
[Text Abstract on PubMed]

Actin-binding proteins regulate the work performed by myosin II motors on single actin filaments.
Janson LW, Sellers JR, Taylor DL.
Cell Motil. Cytoskeleton. 1992;22(4):274-80.
[Text Abstract on PubMed]

Catalytic fragment of protein kinase C exhibits altered substrate specificity toward smooth muscle myosin light chain.
Nakabayashi H, Sellers JR, Huang KP.
FEBS Lett. 1991 Dec 2;294(1-2):144-8.
[Text Abstract on PubMed]

A giant step for myosin.
Sellers JR, Homsher E.
Curr. Biol. 1991 Dec;1(6):347-9.
[Text Abstract on PubMed]

Caldesmon, a novel regulatory protein in smooth muscle and nonmuscle actomyosin systems.
Sobue K, Sellers JR.
J. Biol. Chem. 1991 Jul 5;266(19):12115-8.
[Text Abstract on PubMed]

Caldesmon phosphorylation in intact human platelets by cAMP-dependent protein kinase and protein kinase C.
Hettasch JM, Sellers JR.
J. Biol. Chem. 1991 Jun 25;266(18):11876-81.
[Text Abstract on PubMed]

Influence of the cardiac myosin hinge region on contractile activity.
Margossian SS, Krueger JW, Sellers JR, Cuda G, Caulfield JB, Norton P, Slayter HS.
Proc. Natl. Acad. Sci. U.S.A. 1991 Jun 1;88(11):4941-5.
[Text Abstract on PubMed]

Regulation of cytoplasmic and smooth muscle myosin.
Sellers JR.
Curr. Opin. Cell Biol. 1991 Feb;3(1):98-104.
[Text Abstract on PubMed]

Identification of the serine residue phosphorylated by protein kinase C in vertebrate nonmuscle myosin heavy chains.
Conti MA, Sellers JR, Adelstein RS, Elzinga M.
Biochemistry. 1991 Jan 29;30(4):966-70.
[Text Abstract on PubMed]

The use of native thick filaments in in vitro motility assays.
Sellers JR, Han YJ, Kachar B.
J. Cell Sci. Suppl. 1991;14:67-71.
[Text Abstract on PubMed]

Characterization of in vitro motility assays using smooth muscle and cytoplasmic myosins.
Umemoto S, Sellers JR.
J. Biol. Chem. 1990 Sep 5;265(25):14864-9.
[Text Abstract on PubMed]

Substance P contracts bovine tracheal smooth muscle via activation of myosin light chain kinase.
Corson MA, Sellers JR, Adelstein RS, Schoenberg M.
Am. J. Physiol. 1990 Aug;259(2 Pt 1):C258-65.
[Text Abstract on PubMed]

Polarity and velocity of sliding filaments: control of direction by actin and of speed by myosin.
Sellers JR, Kachar B.
Science. 1990 Jul 27;249(4967):406-8.
[Text Abstract on PubMed]

Calmodulin dissociation regulates brush border myosin I (110-kD-calmodulin) mechanochemical activity in vitro.
Collins K, Sellers JR, Matsudaira P.
J. Cell Biol. 1990 Apr;110(4):1137-47.
[Text Abstract on PubMed]

Formation of new quasi-crystalline ordered aggregates by gizzard myosin.
Margossian SS, Sellers JR, Watkins SC, Slayter HS.
J. Muscle Res. Cell. Motil. 1989 Dec;10(6):413-26.
[Text Abstract on PubMed]

In situ phosphorylation of human platelet myosin heavy and light chains by protein kinase C.
Kawamoto S, Bengur AR, Sellers JR, Adelstein RS.
J. Biol. Chem. 1989 Feb 5;264(4):2258-65.
[Text Abstract on PubMed]

Effect of multiple phosphorylations of smooth muscle and cytoplasmic myosins on movement in an in vitro motility assay.
Umemoto S, Bengur AR, Sellers JR.
J. Biol. Chem. 1989 Jan 25;264(3):1431-6.
[Text Abstract on PubMed]

Effect of multiple phosphorylations on movement of smooth muscle and cytoplasmic myosin.
Sellers JR, Umemoto S.
Adv. Exp. Med. Biol. 1989;255:299-304.
[Text Abstract on PubMed]

In situ phosphorylation of human platelet and rat basophilic leukemia cell (RBL-2H3) myosin heavy chain and light chain.
Adelstein RS, Beaven MA, Bengur AR, Kawamoto S, Ludowyke RI, Peleg I, Sellers JR.
Adv. Exp. Med. Biol. 1989;255:289-97.
[Text Abstract on PubMed]

Preparation and characterization of heavy meromyosin and subfragment 1 from vertebrate cytoplasmic myosins.
Sellers JR, Soboeiro MS, Faust K, Bengur AR, Harvey EV.
Biochemistry. 1988 Sep 6;27(18):6977-82.
[Text Abstract on PubMed]

Sequence of the sites phosphorylated by protein kinase C in the smooth muscle myosin light chain.
Bengur AR, Robinson EA, Appella E, Sellers JR.
J. Biol. Chem. 1987 Jun 5;262(16):7613-7.
[Text Abstract on PubMed]

Effect of phosphorylation on the binding of smooth muscle heavy meromyosin X ADP to actin.
Greene LE, Sellers JR.
J. Biol. Chem. 1987 Mar 25;262(9):4177-81.
[Text Abstract on PubMed]

Effects of calcium on vascular smooth muscle contraction.
Adelstein RS, Sellers JR.
Am. J. Cardiol. 1987 Jan 30;59(3):4B-10B.
[Text Abstract on PubMed]

The effects of caldesmon on smooth muscle heavy actomeromyosin ATPase activity and binding of heavy meromyosin to actin.
Lash JA, Sellers JR, Hathaway DR.
J. Biol. Chem. 1986 Dec 5;261(34):16155-60.
[Text Abstract on PubMed]

Mechanism of the phosphorylation-dependent regulation of smooth muscle heavy meromyosin.
Sellers JR.
J. Biol. Chem. 1985 Dec 15;260(29):15815-9.
[Text Abstract on PubMed]

Light chain phosphorylation regulates the movement of smooth muscle myosin on actin filaments.
Sellers JR, Spudich JA, Sheetz MP.
J. Cell Biol. 1985 Nov;101(5 Pt 1):1897-902.
[Text Abstract on PubMed]

Localization and topography of antigenic domains within the heavy chain of smooth muscle myosin.
Schneider MD, Sellers JR, Vahey M, Preston YA, Adelstein RS.
J. Cell Biol. 1985 Jul;101(1):66-72.
[Text Abstract on PubMed]

Localization of a light-chain binding site on smooth muscle myosin revealed by light-chain overlay of sodium dodecyl sulfate-polyacrylamide electrophoretic gels.
Sellers JR, Harvey EV.
J. Biol. Chem. 1984 Nov 25;259(22):14203-7.
[Text Abstract on PubMed]

Purification of myosin light chain kinase from Limulus muscle.
Sellers JR, Harvey EV.
Biochemistry. 1984 Nov 20;23(24):5821-6.
[Text Abstract on PubMed]

Proteolytic susceptibility of both isolated and bound light chains from various myosins to myopathic hamster protease.
Margossian SS, Chantler PD, Sellers JR, Malhotra A, Stafford WF, Slayter HS.
J. Biol. Chem. 1984 Nov 10;259(21):13534-40.
[Text Abstract on PubMed]

Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase.
Nishikawa M, Sellers JR, Adelstein RS, Hidaka H.
J. Biol. Chem. 1984 Jul 25;259(14):8808-14.
[Text Abstract on PubMed]

The binding of smooth muscle myosin light chain kinase and phosphatases to actin and myosin.
Sellers JR, Pato MD.
J. Biol. Chem. 1984 Jun 25;259(12):7740-6.
[Text Abstract on PubMed]

Actin of Naegleria gruberi. Absence of N tau-methylhistidine.
Sussman DJ, Sellers JR, Flicker P, Lai EY, Cannon LE, Szent-Györgyi AG, Fulton C.
J. Biol. Chem. 1984 Jun 10;259(11):7349-54.
[Text Abstract on PubMed]

Phosphorylation and activation of smooth muscle myosin by Acanthamoeba myosin I heavy chain kinase.
Hammer, Sellers JR, Korn ED.
J. Biol. Chem. 1984 Mar 10;259(5):3224-9.
[Text Abstract on PubMed]

The apparently negatively cooperative phosphorylation of smooth muscle myosin at low ionic strength is related to its filamentous state.
Sellers JR, Chock PB, Adelstein RS.
J. Biol. Chem. 1983 Dec 10;258(23):14181-8.
[Text Abstract on PubMed]

Binding of gizzard smooth muscle myosin subfragment 1 to actin in the presence and absence of adenosine 5'-triphosphate.
Greene LE, Sellers JR, Eisenberg E, Adelstein RS.
Biochemistry. 1983 Feb 1;22(3):530-5.
[Text Abstract on PubMed]

The binding of smooth muscle heavy meromyosin to actin in the presence of ATP. Effect of phosphorylation.
Sellers JR, Eisenberg E, Adelstein RS.
J. Biol. Chem. 1982 Dec 10;257(23):13880-3.
[Text Abstract on PubMed]

Regulation of smooth muscle contractile proteins by calmodulin and cyclic AMP.
Adelstein RS, Sellers JR, Conti MA, Pato MD, de Lanerolle P.
Fed. Proc. 1982 Oct;41(12):2873-8.
[Text Abstract on PubMed]

Regulation of actin-myosin interaction by reversible phosphorylation of myosin and myosin kinase.
Adelstein RS, Pato MD, Sellers JR, de Lanerolle P, Conti MA.
Cold Spring Harb. Symp. Quant. Biol. 1982;46 Pt 2:921-8.
[Text Abstract on PubMed]

Regulation of contractile proteins by reversible phosphorylation of myosin and myosin kinase.
Adelstein RS, Pato MD, Sellers JR, de Lanerolle P, Conti MA.
Soc. Gen. Physiol. Ser. 1982;37:273-81.
[Text Abstract on PubMed]

Reversible phosphorylation of smooth muscle myosin, heavy meromyosin, and platelet myosin.
Sellers JR, Pato MD, Adelstein RS.
J. Biol. Chem. 1981 Dec 25;256(24):13137-42.
[Text Abstract on PubMed]

Phosphorylation-dependent regulation of Limulus myosin.
Sellers JR.
J. Biol. Chem. 1981 Sep 10;256(17):9274-8.
[Text Abstract on PubMed]

Cooperativity in scallop myosin.
Chantler PD, Sellers JR, Szent-Györgyi AG.
Biochemistry. 1981 Jan 6;20(1):210-6.
[Text Abstract on PubMed]

Hybrid formation between scallop myofibrils and foreign regulatory light-chains.
Sellers JR, Chantler PD, Szent-Györgyi AG.
J. Mol. Biol. 1980 Dec 15;144(3):223-45.
[Text Abstract on PubMed]