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Alan T. Remaley, M.D., Ph.D.

Publications


Principal Investigator thumbnail image

Alan T. Remaley
Senior Investigator

P: +1 301 402 9796
F: +1 301 402 1885
aremaley1@mail.nih.gov


Full Publications Listing

Evaluation of four different equations for calculating LDL-C with eight different direct HDL-C assays.
Oliveira MJ, van Deventer HE, Bachmann LM, Warnick GR, Nakajima K, Nakamura M, Sakurabayashi I, Kimberly MM, Shamburek RD, Korzun WJ, Myers GL, Miller WG, Remaley AT.
Clin Chim Acta. 2013 Aug 23;423:135-40.
[Text Abstract on PubMed]

Insulin and extremity muscle mass in overweight and obese women.
Leon B, Jenkins S, Pepin K, Chaudhry H, Smith K, Zalos G, Miller BV 3rd, Chen KY, Remaley AT, Waclawiw MA, Sumner AE, Cannon RO 3rd.
Int J Obes (Lond). 2013 Mar 28.
[Text Abstract on PubMed]

Functional Diversity of HDL Cargo.
Vickers KC, Remaley AT.
J Lipid Res. 2013 Mar 26.
[Text Abstract on PubMed]

Gastrointestinal permeability in patients with irritable bowel syndrome assessed using a four probe permeability solution.
Del Valle-Pinero AY, Van Deventer HE, Fourie NH, Martino AC, Patel NS, Remaley AT, Henderson WA.
Clin Chim Acta. 2013 Mar 15;418:97-101.
[Text Abstract on PubMed]

Apolipoprotein A-II: still second fiddle in high-density lipoprotein metabolism?
Remaley AT.
Arterioscler Thromb Vasc Biol. 2013 Feb ;33(2):166-7.
[Text Abstract on PubMed]

Association of apolipoprotein B and nuclear magnetic resonance spectroscopy-derived LDL particle number with outcomes in 25 clinical studies: assessment by the AACC Lipoprotein and Vascular Diseases Division Working Group on Best Practices.
null null, Cole TG, Contois JH, Csako G, McConnell JP, Remaley AT, Devaraj S, Hoefner DM, Mallory T, Sethi AA, Warnick GR.
Clin Chem. 2013 May ;59(5):752-70.
[Text Abstract on PubMed]

Complexity of microRNA function and the role of isomiRs in lipid homeostasis.
Vickers KC, Sethupathy P, Baran-Gale J, Remaley AT.
J Lipid Res. 2013 May ;54(5):1182-91.
[Text Abstract on PubMed]

Oxidized high-density lipoprotein is associated with increased plasma glucose in non-diabetic dyslipidemic subjects.
Kotani K, Sakane N, Ueda M, Mashiba S, Hayase Y, Tsuzaki K, Yamada T, Remaley AT.
Clin. Chim. Acta. 2012 Dec 24;414:125-9.
[Text Abstract on PubMed]

d-Tocopherol Reduces Lipid Accumulation in Niemann-Pick Type C1 and Wolman Cholesterol Storage Disorders.
Xu M, Liu K, Swaroop M, Porter FD, Sidhu R, Finkes S, Ory DS, Marugan JJ, Xiao J, Southall N, Pavan WJ, Davidson C, Walkley SU, Remaley AT, Baxa U, Sun W, McKew JC, Austin CP, Zheng W.
J. Biol. Chem. 2012 Nov 16;287(47):39349-60.
[Text Abstract on PubMed]

Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity.
Madenspacher JH, Azzam KM, Gong W, Gowdy KM, Vitek MP, Laskowitz DT, Remaley AT, Wang JM, Fessler MB.
J. Biol. Chem. 2012 Nov 1.
[Text Abstract on PubMed]

Reference intervals for plasma free metanephrines with an age adjustment for normetanephrine for optimized laboratory testing of phaeochromocytoma.
Eisenhofer G, Lattke P, Herberg M, Siegert G, Qin N, Därr R, Hoyer J, Villringer A, Prejbisz A, Januszewicz A, Remaley A, Martucci V, Pacak K, Ross HA, Sweep FC, Lenders JW.
Ann. Clin. Biochem. 2012 Oct 12.
[Text Abstract on PubMed]

Identification and profiling of targeted oxidized linoleic acid metabolites in rat plasma by quadrupole time-of-flight mass spectrometry.
Yuan ZX, Rapoport SI, Soldin SJ, Remaley AT, Taha AY, Kellom M, Gu J, Sampson M, Ramsden CE.
Biomed. Chromatogr. 2012 Oct 5.
[Text Abstract on PubMed]

Hydrophobic Amino Acids in the Hinge Region of the 5A Apolipoprotein Mimetic Peptide are Essential for Promoting Cholesterol Efflux by the ABCA1 Transporter.
Sviridov DO, Andrianov AM, Anishchenko IV, Stonik JA, Amar MJ, Turner S, Remaley AT.
J. Pharmacol. Exp. Ther. 2012 Oct 5.
[Text Abstract on PubMed]

Diet-induced weight loss in overweight or obese women and changes in high-density lipoprotein levels and function.
Aicher BO, Haser EK, Freeman LA, Carnie AV, Stonik JA, Wang X, Remaley AT, Kato GJ, Cannon.
Obesity (Silver Spring). 2012 Oct;20(10):2057-62.
[Text Abstract on PubMed]

Apolipoprotein A-I attenuates ovalbumin-induced neutrophilic airway inflammation via a granulocyte colony-stimulating factor-dependent mechanism.
Dai C, Yao X, Keeran KJ, Zywicke GJ, Qu X, Yu ZX, Dagur PK, McCoy JP, Remaley AT, Levine SJ.
Am. J. Respir. Cell Mol. Biol. 2012 Aug;47(2):186-95.
[Text Abstract on PubMed]

A high-throughput sphingomyelinase assay using natural substrate.
Xu M, Liu K, Southall N, Marugan JJ, Remaley AT, Zheng W.
Anal Bioanal Chem. 2012 Aug;404(2):407-14.
[Text Abstract on PubMed]

MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia.
Vickers KC, Shoucri BM, Levin MG, Wu H, Pearson DS, Osei-Hwedieh D, Collins FS, Remaley AT, Sethupathy P.
Hepatology. 2012 Jul 6.
[Text Abstract on PubMed]

Unmedicated, remitted patients with major depression have decreased serum immunoglobulin A.
Gold PW, Pavlatou MG, Carlson PJ, Luckenbaugh DA, Costello R, Bonne O, Csako G, Drevets WC, Remaley AT, Charney DS, Neumeister A, Kling MA.
Neurosci. Lett. 2012 Jun 27;520(1):1-5.
[Text Abstract on PubMed]

Sleeping parathyroid tumor: rapid hyperfunction after removal of the dominant tumor.
Yavuz S, Simonds WF, Weinstein LS, Collins MT, Kebebew E, Nilubol N, Phan GQ, Libutti SK, Remaley AT, Van Deventer M, Marx SJ.
J. Clin. Endocrinol. Metab. 2012 Jun;97(6):1834-41.
[Text Abstract on PubMed]

ATP binding cassette transporter G1 deletion induces IL-17-dependent dysregulation of pulmonary adaptive immunity.
Draper DW, Gowdy KM, Madenspacher JH, Wilson RH, Whitehead GS, Nakano H, Pandiri AR, Foley JF, Remaley AT, Cook DN, Fessler MB.
J. Immunol. 2012 Jun 1;188(11):5327-36.
[Text Abstract on PubMed]

Cellular pregnenolone esterification by acyl-CoA:cholesterol acyltransferase.
Rogers MA, Liu J, Kushnir MM, Bryleva E, Rockwood AL, Meikle AW, Shapiro D, Vaisman BL, Remaley AT, Chang CC, Chang TY.
J. Biol. Chem. 2012 May 18;287(21):17483-92.
[Text Abstract on PubMed]

Commentary.
Remaley AT.
Clin. Chem. 2012 May;58(5):830.
[Text Abstract on PubMed]

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport.
Rosenson RS, Brewer, Davidson WS, Fayad ZA, Fuster V, Goldstein J, Hellerstein M, Jiang XC, Phillips MC, Rader DJ, Remaley AT, Rothblat GH, Tall AR, Yvan-Charvet L.
Circulation. 2012 Apr 17;125(15):1905-19.
[Text Abstract on PubMed]

Elevated vitamin B12 levels in autoimmune lymphoproliferative syndrome attributable to elevated haptocorrin in lymphocytes.
Bowen RA, Dowdell KC, Dale JK, Drake SK, Fleisher TA, Hortin GL, Remaley AT, Nexo E, Rao VK.
Clin. Biochem. 2012 Apr;45(6):490-2.
[Text Abstract on PubMed]

Lipid-based carriers of microRNAs and intercellular communication.
Vickers KC, Remaley AT.
Curr. Opin. Lipidol. 2012 Apr;23(2):91-7.
[Text Abstract on PubMed]

Class B scavenger receptor types I and II and CD36 targeting improves sepsis survival and acute outcomes in mice.
Leelahavanichkul A, Bocharov AV, Kurlander R, Baranova IN, Vishnyakova TG, Souza AC, Hu X, Doi K, Vaisman B, Amar M, Sviridov D, Chen Z, Remaley AT, Csako G, Patterson AP, Yuen PS, Star RA, Eggerman TL.
J. Immunol. 2012 Mar 15;188(6):2749-58.
[Text Abstract on PubMed]

Mechanism of cholesterol efflux in humans after infusion of reconstituted high-density lipoprotein.
Hoang A, Drew BG, Low H, Remaley AT, Nestel P, Kingwell BA, Sviridov D.
Eur. Heart J. 2012 Mar;33(5):657-65.
[Text Abstract on PubMed]

High-density lipoprotein cholesterol efflux, nitration of apolipoprotein A-I, and endothelial function in obese women.
Vazquez E, Sethi AA, Freeman L, Zalos G, Chaudhry H, Haser E, Aicher BO, Aponte A, Gucek M, Kato GJ, Waclawiw MA, Remaley AT, Cannon.
Am. J. Cardiol. 2012 Feb 15;109(4):527-32.
[Text Abstract on PubMed]

Pulmonary artery pressure and iron deficiency in patients with upregulation of hypoxia sensing due to homozygous VHL(R200W) mutation (Chuvash polycythemia).
Sable CA, Aliyu ZY, Dham N, Nouraie M, Sachdev V, Sidenko S, Miasnikova GY, Polyakova LA, Sergueeva AI, Okhotin DJ, Bushuev V, Remaley AT, Niu X, Castro OL, Gladwin MT, Kato GJ, Prchal JT, Gordeuk VR.
Haematologica. 2012 Feb;97(2):193-200.
[Text Abstract on PubMed]

Human apolipoprotein E genotypes differentially modify house dust mite-induced airway disease in mice.
Yao X, Dai C, Fredriksson K, Lam J, Gao M, Keeran KJ, Nugent GZ, Qu X, Yu ZX, Jeffries N, Lin J, Kaler M, Shamburek R, Costello R, Csako G, Dahl M, Nordestgaard BG, Remaley AT, Levine SJ.
Am. J. Physiol. Lung Cell Mol. Physiol. 2012 Jan 15;302(2):L206-15.
[Text Abstract on PubMed]

Endothelial expression of human ABCA1 in mice increases plasma HDL cholesterol and reduces diet-induced atherosclerosis.
Vaisman BL, Demosky SJ, Stonik JA, Ghias M, Knapper CL, Sampson ML, Dai C, Levine SJ, Remaley AT.
J. Lipid Res. 2012 Jan;53(1):158-67.
[Text Abstract on PubMed]

Apolipoprotein mimetic peptides: a new approach for the treatment of asthma.
Yao X, Vitek MP, Remaley AT, Levine SJ.
Front Pharmacol. 2012;3:37.
[Text Abstract on PubMed]

Metabolic function of a suboptimal transplanted islet mass in nonhuman primates on rapamycin monotherapy.
Soleimanpour SA, Hirshberg B, Bunnell DJ, Sumner AE, Ader M, Remaley AT, Rother KI, Rickels MR, Harlan DM.
Cell Transplant. 2012;21(6):1297-304.
[Text Abstract on PubMed]

Selective endothelial overexpression of arginase II induces endothelial dysfunction and hypertension and enhances atherosclerosis in mice.
Vaisman BL, Andrews KL, Khong SM, Wood KC, Moore XL, Fu Y, Kepka-Lenhart DM, Morris, Remaley AT, Chin-Dusting JP.
PLoS ONE. 2012;7(7):e39487.
[Text Abstract on PubMed]

Plasma uric acid levels correlate with inflammation and disease severity in Malian children with Plasmodium falciparum malaria.
Lopera-Mesa TM, Mita-Mendoza NK, van de Hoef DL, Doumbia S, Konaté D, Doumbouya M, Gu W, Traoré K, Diakité SA, Remaley AT, Anderson JM, Rodriguez A, Fay MP, Long CA, Diakité M, Fairhurst RM.
PLoS ONE. 2012;7(10):e46424.
[Text Abstract on PubMed]

Circulating thyroxine, thyroid-stimulating hormone, and hypothyroid status and the risk of prostate cancer.
Mondul AM, Weinstein SJ, Bosworth T, Remaley AT, Virtamo J, Albanes D.
PLoS ONE. 2012;7(10):e47730.
[Text Abstract on PubMed]

Anti-haemolytic effect of senicapoc and decrease in NT-proBNP in adults with sickle cell anaemia.
Minniti CP, Wilson J, Mendelsohn L, Rigdon GC, Stocker JW, Remaley AT, Kato GJ.
Br. J. Haematol. 2011 Dec;155(5):634-6.
[Text Abstract on PubMed]

Allostatic load and health status of African Americans and whites.
Deuster PA, Kim-Dorner SJ, Remaley AT, Poth M.
Am J Health Behav. 2011 Nov;35(6):641-53.
[Text Abstract on PubMed]

New kids on the block: the emerging role of apolipoproteins in the pathogenesis and treatment of asthma.
Yao X, Remaley AT, Levine SJ.
Chest. 2011 Oct;140(4):1048-54.
[Text Abstract on PubMed]

"Who's on first": determining the roster for the key players in the reverse cholesterol transport pathway.
Remaley AT.
Atherosclerosis. 2011 Oct;218(2):287-9.
[Text Abstract on PubMed]

Zinc finger protein tristetraprolin interacts with CCL3 mRNA and regulates tissue inflammation.
Kang JG, Amar MJ, Remaley AT, Kwon J, Blackshear PJ, Wang PY, Hwang PM.
J. Immunol. 2011 Sep 1;187(5):2696-701.
[Text Abstract on PubMed]

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells.
Kim KY, Stevens MV, Akter MH, Rusk SE, Huang RJ, Cohen A, Noguchi A, Springer D, Bocharov AV, Eggerman TL, Suen DF, Youle RJ, Amar M, Remaley AT, Sack MN.
J. Clin. Invest. 2011 Sep;121(9):3701-12.
[Text Abstract on PubMed]

Clinical utility of inflammatory markers and advanced lipoprotein testing: advice from an expert panel of lipid specialists.
Davidson MH, Ballantyne CM, Jacobson TA, Bittner VA, Braun LT, Brown AS, Brown WV, Cromwell WC, Goldberg RB, McKenney JM, Remaley AT, Sniderman AD, Toth PP, Tsimikas S, Ziajka PE, Maki KC, Dicklin MR.
J Clin Lipidol. 2011 Sep-Oct;5(5):338-67.
[Text Abstract on PubMed]

NT-pro brain natriuretic peptide levels and the risk of death in the cooperative study of sickle cell disease.
Machado RF, Hildesheim M, Mendelsohn L, Remaley AT, Kato GJ, Gladwin MT.
Br. J. Haematol. 2011 Aug;154(4):512-20.
[Text Abstract on PubMed]

Helix stabilization of amphipathic peptides by hydrocarbon stapling increases cholesterol efflux by the ABCA1 transporter.
Sviridov DO, Ikpot IZ, Stonik J, Drake SK, Amar M, Osei-Hwedieh DO, Piszczek G, Turner S, Remaley AT.
Biochem. Biophys. Res. Commun. 2011 Jul 8;410(3):446-51.
[Text Abstract on PubMed]

Lecithin cholesterol acyltransferase: an anti- or pro-atherogenic factor?
Rousset X, Shamburek R, Vaisman B, Amar M, Remaley AT.
Curr Atheroscler Rep. 2011 Jun;13(3):249-56.
[Text Abstract on PubMed]

HDL and sphingosine-1-phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion.
Sekine Y, Suzuki K, Remaley AT.
Prostate. 2011 May 15;71(7):690-9.
[Text Abstract on PubMed]

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins.
Vickers KC, Palmisano BT, Shoucri BM, Shamburek RD, Remaley AT.
Nat. Cell Biol. 2011 Apr;13(4):423-33.
[Text Abstract on PubMed]

Apolipoprotein mimetic peptides: Mechanisms of action as anti-atherogenic agents.
Osei-Hwedieh DO, Amar M, Sviridov D, Remaley AT.
Pharmacol. Ther. 2011 Apr;130(1):83-91.
[Text Abstract on PubMed]

High fat diet reduces the expression of glutathione peroxidase 3 in mouse prostate.
Sekine Y, Osei-Hwedieh D, Matsuda K, Raghavachari N, Liu D, Furuya Y, Koike H, Suzuki K, Remaley AT.
Prostate. 2011 Mar 3.
[Text Abstract on PubMed]

Non-HDL cholesterol shows improved accuracy for cardiovascular risk score classification compared to direct or calculated LDL cholesterol in a dyslipidemic population.
van Deventer HE, Miller WG, Myers GL, Sakurabayashi I, Bachmann LM, Caudill SP, Dziekonski A, Edwards S, Kimberly MM, Korzun WJ, Leary ET, Nakajima K, Nakamura M, Shamburek RD, Vetrovec GW, Warnick GR, Remaley AT.
Clin. Chem. 2011 Mar;57(3):490-501.
[Text Abstract on PubMed]

HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events.
Rosenson RS, Brewer, Chapman MJ, Fazio S, Hussain MM, Kontush A, Krauss RM, Otvos JD, Remaley AT, Schaefer EJ.
Clin. Chem. 2011 Mar;57(3):392-410.
[Text Abstract on PubMed]

5A, an apolipoprotein A-I mimetic peptide, attenuates the induction of house dust mite-induced asthma.
Yao X, Dai C, Fredriksson K, Dagur PK, McCoy JP, Qu X, Yu ZX, Keeran KJ, Zywicke GJ, Amar MJ, Remaley AT, Levine SJ.
J. Immunol. 2011 Jan 1;186(1):576-83.
[Text Abstract on PubMed]

Inverse log-linear relationship between thyroid-stimulating hormone and free thyroxine measured by direct analog immunoassay and tandem mass spectrometry.
van Deventer HE, Mendu DR, Remaley AT, Soldin SJ.
Clin. Chem. 2011 Jan;57(1):122-7.
[Text Abstract on PubMed]

S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease.
Argraves KM, Sethi AA, Gazzolo PJ, Wilkerson BA, Remaley AT, Tybjaerg-Hansen A, Nordestgaard BG, Yeatts SD, Nicholas KS, Barth JL, Argraves WS.
Lipids Health Dis. 2011;10:70.
[Text Abstract on PubMed]

Intranasal delivery of E-selectin reduces atherosclerosis in ApoE-/- mice.
Li X, Johnson KR, Bryant M, Elkahloun AG, Amar M, Remaley AT, De Silva R, Hallenbeck JM, Quandt JA.
PLoS ONE. 2011;6(6):e20620.
[Text Abstract on PubMed]

Minimal changes in environmental temperature result in a significant increase in energy expenditure and changes in the hormonal homeostasis in healthy adults.
Celi FS, Brychta RJ, Linderman JD, Butler PW, Alberobello AT, Smith S, Courville AB, Lai EW, Costello R, Skarulis MC, Csako G, Remaley A, Pacak K, Chen KY.
Eur. J. Endocrinol. 2010 Dec;163(6):863-72.
[Text Abstract on PubMed]

Studies on solvatochromic properties of aminophenylstyryl-quinolinum dye, LDS 798, and its application in studying submicron lipid based structure.
Sarkar P, Luchowski R, Raut S, Sabnis N, Remaley A, Lacko AG, Thamake S, Gryczynski Z, Gryczynski I.
Biophys. Chem. 2010 Dec;153(1):61-9.
[Text Abstract on PubMed]

Apolipoprotein E negatively regulates house dust mite-induced asthma via a low-density lipoprotein receptor-mediated pathway.
Yao X, Fredriksson K, Yu ZX, Xu X, Raghavachari N, Keeran KJ, Zywicke GJ, Kwak M, Amar MJ, Remaley AT, Levine SJ.
Am. J. Respir. Crit. Care Med. 2010 Nov 15;182(10):1228-38.
[Text Abstract on PubMed]

Effect of recombinant human lecithin cholesterol acyltransferase infusion on lipoprotein metabolism in mice.
Rousset X, Vaisman B, Auerbach B, Krause BR, Homan R, Stonik J, Csako G, Shamburek R, Remaley AT.
J. Pharmacol. Exp. Ther. 2010 Oct;335(1):140-8.
[Text Abstract on PubMed]

The role of noncoding "junk DNA" in cardiovascular disease.
Vickers KC, Palmisano BT, Remaley AT.
Clin. Chem. 2010 Oct;56(10):1518-20.
[Text Abstract on PubMed]

Serum estrogen and tumor-positive estrogen receptor-alpha are strong prognostic classifiers of non-small-cell lung cancer survival in both men and women.
Olivo-Marston SE, Mechanic LE, Mollerup S, Bowman ED, Remaley AT, Forman MR, Skaug V, Zheng YL, Haugen A, Harris CC.
Carcinogenesis. 2010 Oct;31(10):1778-86.
[Text Abstract on PubMed]

Apolipoprotein A-I and serum amyloid A plasma levels are biomarkers of acute painful episodes in patients with sickle cell disease.
Tumblin A, Tailor A, Hoehn GT, Mack AK, Mendelsohn L, Freeman L, Xu X, Remaley AT, Munson PJ, Suffredini AF, Kato GJ.
Haematologica. 2010 Sep;95(9):1467-72.
[Text Abstract on PubMed]

High-density lipoprotein induces proliferation and migration of human prostate androgen-independent cancer cells by an ABCA1-dependent mechanism.
Sekine Y, Demosky SJ, Stonik JA, Furuya Y, Koike H, Suzuki K, Remaley AT.
Mol. Cancer Res. 2010 Sep;8(9):1284-94.
[Text Abstract on PubMed]

5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice.
Amar MJ, D'Souza W, Turner S, Demosky S, Sviridov D, Stonik J, Luchoomun J, Voogt J, Hellerstein M, Sviridov D, Remaley AT.
J. Pharmacol. Exp. Ther. 2010 Aug;334(2):634-41.
[Text Abstract on PubMed]

ATP-binding cassette transporter G1 deficiency dysregulates host defense in the lung.
Draper DW, Madenspacher JH, Dixon D, King DH, Remaley AT, Fessler MB.
Am. J. Respir. Crit. Care Med. 2010 Aug 1;182(3):404-12.
[Text Abstract on PubMed]

Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1.
Morrow MP, Grant A, Mujawar Z, Dubrovsky L, Pushkarsky T, Kiselyeva Y, Jennelle L, Mukhamedova N, Remaley AT, Kashanchi F, Sviridov D, Bukrinsky M.
Mol. Pharmacol. 2010 Aug;78(2):215-25.
[Text Abstract on PubMed]

Structure/function relationships of apolipoprotein a-I mimetic peptides: implications for antiatherogenic activities of high-density lipoprotein.
D'Souza W, Stonik JA, Murphy A, Demosky SJ, Sethi AA, Moore XL, Chin-Dusting J, Remaley AT, Sviridov D.
Circ. Res. 2010 Jul 23;107(2):217-27.
[Text Abstract on PubMed]

High pre-beta1 HDL concentrations and low lecithin: cholesterol acyltransferase activities are strong positive risk markers for ischemic heart disease and independent of HDL-cholesterol.
Sethi AA, Sampson M, Warnick R, Muniz N, Vaisman B, Nordestgaard BG, Tybjaerg-Hansen A, Remaley AT.
Clin. Chem. 2010 Jul;56(7):1128-37.
[Text Abstract on PubMed]

Inhibition of mesothelin-CA-125 interaction in patients with mesothelioma by the anti-mesothelin monoclonal antibody MORAb-009: Implications for cancer therapy.
Hassan R, Schweizer C, Lu KF, Schuler B, Remaley AT, Weil SC, Pastan I.
Lung Cancer. 2010 Jun;68(3):455-9.
[Text Abstract on PubMed]

Seven direct methods for measuring HDL and LDL cholesterol compared with ultracentrifugation reference measurement procedures.
Miller WG, Myers GL, Sakurabayashi I, Bachmann LM, Caudill SP, Dziekonski A, Edwards S, Kimberly MM, Korzun WJ, Leary ET, Nakajima K, Nakamura M, Nilsson G, Shamburek RD, Vetrovec GW, Warnick GR, Remaley AT.
Clin. Chem. 2010 Jun;56(6):977-86.
[Text Abstract on PubMed]

Lipid levels in sickle-cell disease associated with haemolytic severity, vascular dysfunction and pulmonary hypertension.
Zorca S, Freeman L, Hildesheim M, Allen D, Remaley AT, Taylor, Kato GJ.
Br. J. Haematol. 2010 May;149(3):436-45.
[Text Abstract on PubMed]

Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver.
Bektas M, Allende ML, Lee BG, Chen W, Amar MJ, Remaley AT, Saba JD, Proia RL.
J. Biol. Chem. 2010 Apr 2;285(14):10880-9.
[Text Abstract on PubMed]

MicroRNAs in atherosclerosis and lipoprotein metabolism.
Vickers KC, Remaley AT.
Curr Opin Endocrinol Diabetes Obes. 2010 Apr;17(2):150-5.
[Text Abstract on PubMed]

Diagnostic criteria for metabolic syndrome: caucasians versus African-Americans.
Zeno SA, Deuster PA, Davis JL, Kim-Dorner SJ, Remaley AT, Poth M.
Metab Syndr Relat Disord. 2010 Apr;8(2):149-56.
[Text Abstract on PubMed]

Should triglycerides and the triglycerides to high-density lipoprotein cholesterol ratio be used as surrogates for insulin resistance?
Kim-Dorner SJ, Deuster PA, Zeno SA, Remaley AT, Poth M.
Metab. Clin. Exp. 2010 Feb;59(2):299-304.
[Text Abstract on PubMed]

The 5A apolipoprotein A-I mimetic peptide displays antiinflammatory and antioxidant properties in vivo and in vitro.
Tabet F, Remaley AT, Segaliny AI, Millet J, Yan L, Nakhla S, Barter PJ, Rye KA, Lambert G.
Arterioscler. Thromb. Vasc. Biol. 2010 Feb;30(2):246-52.
[Text Abstract on PubMed]

Impact of blood collection devices on clinical chemistry assays.
Bowen RA, Hortin GL, Csako G, Otañez OH, Remaley AT.
Clin. Biochem. 2010 Jan;43(1-2):4-25.
[Text Abstract on PubMed]

Cardiovascular fitness and risk factors of healthy African Americans and Caucasians.
Zeno SA, Kim-Dorner SJ, Deuster PA, Davis JL, Remaley AT, Poth M.
J Natl Med Assoc. 2010 Jan;102(1):28-35.
[Text Abstract on PubMed]

HDL therapy: two kinds of right?
Murphy AJ, Remaley AT, Sviridov D.
Curr. Pharm. Des. 2010;16(37):4134-47.
[Text Abstract on PubMed]

The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine.
Biesecker LG, Mullikin JC, Facio FM, Turner C, Cherukuri PF, Blakesley RW, Bouffard GG, Chines PS, Cruz P, Hansen NF, Teer JK, Maskeri B, Young AC, NISC Comparative Sequencing Program, Manolio TA, Wilson AF, Finkel T, Hwang P, Arai A, Remaley AT, Sachdev V, Shamburek R, Cannon RO, Green ED.
Genome Res. 2009 Sep;19(9):1665-74.
[Text Abstract on PubMed]

Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein.
Amar MJ, Shamburek RD, Vaisman B, Knapper CL, Foger B, Hoyt, Santamarina-Fojo S, Brewer, Remaley AT.
Metab. Clin. Exp. 2009 Apr;58(4):568-75.
[Text Abstract on PubMed]

Lecithin: cholesterol acyltransferase--from biochemistry to role in cardiovascular disease.
Rousset X, Vaisman B, Amar M, Sethi AA, Remaley AT.
Curr Opin Endocrinol Diabetes Obes. 2009 Apr;16(2):163-71.
[Text Abstract on PubMed]

Thyroid function, the risk of dementia and neuropathologic changes: the Honolulu-Asia aging study.
de Jong FJ, Masaki K, Chen H, Remaley AT, Breteler MM, Petrovitch H, White LR, Launer LJ.
Neurobiol. Aging. 2009 Apr;30(4):600-6.
[Text Abstract on PubMed]

Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr(-/-) murine model of autoimmune lymphoproliferative syndrome (ALPS).
Dowdell KC, Pesnicak L, Hoffmann V, Steadman K, Remaley AT, Cohen JI, Straus SE, Rao VK.
Exp. Hematol. 2009 Apr;37(4):487-94.
[Text Abstract on PubMed]

Trans-splicing into highly abundant albumin transcripts for production of therapeutic proteins in vivo.
Wang J, Mansfield SG, Cote CA, Jiang PD, Weng K, Amar MJ, Brewer, Remaley AT, McGarrity GJ, Garcia-Blanco MA, Puttaraju M.
Mol. Ther. 2009 Feb;17(2):343-51.
[Text Abstract on PubMed]

Proteomic identification of altered apolipoprotein patterns in pulmonary hypertension and vasculopathy of sickle cell disease.
Yuditskaya S, Tumblin A, Hoehn GT, Wang G, Drake SK, Xu X, Ying S, Chi AH, Remaley AT, Shen RF, Munson PJ, Suffredini AF, Kato GJ.
Blood. 2009 Jan 29;113(5):1122-8.
[Text Abstract on PubMed]

Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.
Lindegaard ML, Wassif CA, Vaisman B, Amar M, Wasmuth EV, Shamburek R, Nielsen LB, Remaley AT, Porter FD.
Hum. Mol. Genet. 2008 Dec 1;17(23):3806-13.
[Text Abstract on PubMed]

Asymmetry in the lipid affinity of bihelical amphipathic peptides. A structural determinant for the specificity of ABCA1-dependent cholesterol efflux by peptides.
Sethi AA, Stonik JA, Thomas F, Demosky SJ, Amar M, Neufeld E, Brewer HB, Davidson WS, D'Souza W, Sviridov D, Remaley AT.
J. Biol. Chem. 2008 Nov 21;283(47):32273-82.
[Text Abstract on PubMed]

Role of human CD36 in bacterial recognition, phagocytosis, and pathogen-induced JNK-mediated signaling.
Baranova IN, Kurlander R, Bocharov AV, Vishnyakova TG, Chen Z, Remaley AT, Csako G, Patterson AP, Eggerman TL.
J. Immunol. 2008 Nov 15;181(10):7147-56.
[Text Abstract on PubMed]

High-density lipoprotein reduces the human monocyte inflammatory response.
Murphy AJ, Woollard KJ, Hoang A, Mukhamedova N, Stirzaker RA, McCormick SP, Remaley AT, Sviridov D, Chin-Dusting J.
Arterioscler. Thromb. Vasc. Biol. 2008 Nov;28(11):2071-7.
[Text Abstract on PubMed]

HDL-replacement therapy: mechanism of action, types of agents and potential clinical indications.
Remaley AT, Amar M, Sviridov D.
Expert Rev Cardiovasc Ther. 2008 Oct;6(9):1203-15.
[Text Abstract on PubMed]

Dietary alpha-cyclodextrin lowers low-density lipoprotein cholesterol and alters plasma fatty acid profile in low-density lipoprotein receptor knockout mice on a high-fat diet.
Wagner EM, Jen KL, Artiss JD, Remaley AT.
Metab. Clin. Exp. 2008 Aug;57(8):1046-51.
[Text Abstract on PubMed]

Association of loss-of-function mutations in the ABCA1 gene with high-density lipoprotein cholesterol levels and risk of ischemic heart disease.
Frikke-Schmidt R, Nordestgaard BG, Stene MC, Sethi AA, Remaley AT, Schnohr P, Grande P, Tybjaerg-Hansen A.
JAMA. 2008 Jun 4;299(21):2524-32.
[Text Abstract on PubMed]

Contribution of macromolecular structure to the retention of low-density lipoprotein at arterial branch points.
Kwon GP, Schroeder JL, Amar MJ, Remaley AT, Balaban RS.
Circulation. 2008 Jun 3;117(22):2919-27.
[Text Abstract on PubMed]

In vitro characterization of a monoclonal IgG(kappa) from a patient with planar xanthomatosis.
Horne, Merryman P, Cullinane A, Remaley AT.
Eur. J. Haematol. 2008 Jun;80(6):495-502.
[Text Abstract on PubMed]

Antiatherogenic functionality of high density lipoprotein: how much versus how good.
Sviridov D, Mukhamedova N, Remaley AT, Chin-Dusting J, Nestel P.
J. Atheroscler. Thromb. 2008 Apr;15(2):52-62.
[Text Abstract on PubMed]

The effects of a high-fruit and -vegetable, high-fiber, low-fat dietary intervention on serum concentrations of insulin, glucose, IGF-I and IGFBP-3.
Flood A, Mai V, Pfeiffer R, Kahle L, Remaley AT, Rosen CJ, Lanza E, Schatzkin A.
Eur J Clin Nutr. 2008 Feb;62(2):186-96.
[Text Abstract on PubMed]

Anti-inflammatory and cardioprotective activities of synthetic high-density lipoprotein containing apolipoprotein A-I mimetic peptides.
Gomaraschi M, Calabresi L, Rossoni G, Iametti S, Franceschini G, Stonik JA, Remaley AT.
J. Pharmacol. Exp. Ther. 2008 Feb;324(2):776-83.
[Text Abstract on PubMed]

Gynecologic and hormonal effects of raloxifene in premenopausal women.
Premkumar A, Venzon DJ, Avila N, Johnson DV, Remaley AT, Forman MR, Eng-Wong J, Zujewski J, Stratton P.
Fertil. Steril. 2007 Dec;88(6):1637-44.
[Text Abstract on PubMed]

Elevated serum concentrations of insulin and glucose increase risk of recurrent colorectal adenomas.
Flood A, Mai V, Pfeiffer R, Kahle L, Remaley AT, Lanza E, Schatzkin A.
Gastroenterology. 2007 Nov;133(5):1423-9.
[Text Abstract on PubMed]

Adverse birth outcome among mothers with low serum cholesterol.
Edison RJ, Berg K, Remaley A, Kelley R, Rotimi C, Stevenson RE, Muenke M.
Pediatrics. 2007 Oct;120(4):723-33.
[Text Abstract on PubMed]

Inflammation and iron deficiency in the hypoferremia of obesity.
Yanoff LB, Menzie CM, Denkinger B, Sebring NG, McHugh T, Remaley AT, Yanovski JA.
Int J Obes (Lond). 2007 Sep;31(9):1412-9.
[Text Abstract on PubMed]

The role of different regions of ATP-binding cassette transporter A1 in cholesterol efflux.
Mukhamedova N, Fu Y, Bukrinsky M, Remaley AT, Sviridov D.
Biochemistry. 2007 Aug 21;46(33):9388-98.
[Text Abstract on PubMed]

Old drug, new tricks: the unexpected effect of doxazosin on high-density lipoprotein.
Remaley AT.
Circ. Res. 2007 Jul 20;101(2):116-8.
[Text Abstract on PubMed]

Human serum albumin levels and cardiovascular risk factors in elderly Japanese-American men: the Honolulu Heart Program.
Ha CE, Masaki KH, Petrovitch H, Chen R, Launer L, Bhagavan NV, Remaley AT, Curb JD.
Hawaii Med J. 2007 Jun;66(6):148, 150-2.
[Text Abstract on PubMed]

Apolipoprotein AI mimetic peptides: possible new agents for the treatment of atherosclerosis.
Sethi AA, Amar M, Shamburek RD, Remaley AT.
Curr Opin Investig Drugs. 2007 Mar;8(3):201-12.
[Text Abstract on PubMed]

Differential effect of blood collection tubes on total free fatty acids (FFA) and total triiodothyronine (TT3) concentration: a model for studying interference from tube constituents.
Bowen RA, Vu C, Remaley AT, Hortin GL, Csako G.
Clin. Chim. Acta. 2007 Mar;378(1-2):181-93.
[Text Abstract on PubMed]

Inflammation and IGF-I activate the Akt pathway in breast cancer.
Prueitt RL, Boersma BJ, Howe TM, Goodman JE, Thomas DD, Ying L, Pfiester CM, Yfantis HG, Cottrell JR, Lee DH, Remaley AT, Hofseth LJ, Wink DA, Ambs S.
Int. J. Cancer. 2007 Feb 15;120(4):796-805.
[Text Abstract on PubMed]

Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited.
Basso F, Freeman LA, Ko C, Joyce C, Amar MJ, Shamburek RD, Tansey T, Thomas F, Wu J, Paigen B, Remaley AT, Santamarina-Fojo S, Brewer.
J. Lipid Res. 2007 Jan;48(1):114-26.
[Text Abstract on PubMed]

Sex hormones and neuropathology in elderly men: the HAAS.
Strozyk D, White LR, Petrovitch H, Geerlings MI, Remaley AT, Launer LJ.
Neurobiol. Aging. 2007 Jan;28(1):62-8.
[Text Abstract on PubMed]

Transbilayer phospholipid movements in ABCA1-deficient cells.
Williamson P, Halleck MS, Malowitz J, Ng S, Fan X, Krahling S, Remaley AT, Schlegel RA.
PLoS ONE. 2007;2(8):e729.
[Text Abstract on PubMed]

Enhanced ABCG1 expression increases atherosclerosis in LDLr-KO mice on a western diet.
Basso F, Amar MJ, Wagner EM, Vaisman B, Paigen B, Santamarina-Fojo S, Remaley AT.
Biochem. Biophys. Res. Commun. 2006 Dec 15;351(2):398-404.
[Text Abstract on PubMed]

A comparison of immunometric and radioimmunoassay measurement of ACTH for the differential diagnosis of Cushing's syndrome.
Lindsay JR, Shanmugam VK, Oldfield EH, Remaley AT, Nieman LK.
J. Endocrinol. Invest. 2006 Dec;29(11):983-8.
[Text Abstract on PubMed]

Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity.
Müller M, Klein I, Kopácsi S, Remaley AT, Rajnavölgyi E, Sarkadi B, Váradi A.
FEBS Lett. 2006 Nov 13;580(26):6139-44.
[Text Abstract on PubMed]

CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells.
Vishnyakova TG, Kurlander R, Bocharov AV, Baranova IN, Chen Z, Abu-Asab MS, Tsokos M, Malide D, Basso F, Remaley A, Csako G, Eggerman TL, Patterson AP.
Proc. Natl. Acad. Sci. U.S.A. 2006 Nov 7;103(45):16888-93.
[Text Abstract on PubMed]

ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of pro-atherogenic lipoproteins and enhanced atherosclerosis.
Joyce CW, Wagner EM, Basso F, Amar MJ, Freeman LA, Shamburek RD, Knapper CL, Syed J, Wu J, Vaisman BL, Fruchart-Najib J, Billings EM, Paigen B, Remaley AT, Santamarina-Fojo S, Brewer.
J. Biol. Chem. 2006 Nov 3;281(44):33053-65.
[Text Abstract on PubMed]

Effects of chronic osteoarthritis pain on neuroendocrine function in men.
Khoromi S, Muniyappa R, Nackers L, Gray N, Baldwin H, Wong KA, Matheny LA, Moquin B, Rainer A, Hill S, Remaley A, Johnson LL, Max MB, Blackman MR.
J. Clin. Endocrinol. Metab. 2006 Nov;91(11):4313-8.
[Text Abstract on PubMed]

Endogenous sex hormones, cognitive decline, and future dementia in old men.
Geerlings MI, Strozyk D, Masaki K, Remaley AT, Petrovitch H, Ross GW, White LR, Launer LJ.
Ann. Neurol. 2006 Sep;60(3):346-55.
[Text Abstract on PubMed]

Brain lesions on MRI and endogenous sex hormones in elderly men.
Irie F, Strozyk D, Peila R, Korf ES, Remaley AT, Masaki K, White LR, Launer LJ.
Neurobiol. Aging. 2006 Aug;27(8):1137-44.
[Text Abstract on PubMed]

Human lecithin:cholesterol acyltransferase deficiency: in vivo kinetics of low-density lipoprotein and lipoprotein-X.
Nishiwaki M, Ikewaki K, Bader G, Nazih H, Hannuksela M, Remaley AT, Shamburek RD, Brewer.
Arterioscler. Thromb. Vasc. Biol. 2006 Jun;26(6):1370-5.
[Text Abstract on PubMed]

The prevalence of hypovitaminosis D and secondary hyperparathyroidism in obese Black Americans.
Yanoff LB, Parikh SJ, Spitalnik A, Denkinger B, Sebring NG, Slaughter P, McHugh T, Remaley AT, Yanovski JA.
Clin. Endocrinol. (Oxf). 2006 May;64(5):523-9.
[Text Abstract on PubMed]

Apolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporter.
Nofer JR, Remaley AT, Feuerborn R, Wolinnska I, Engel T, von Eckardstein A, Assmann G.
J. Lipid Res. 2006 Apr;47(4):794-803.
[Text Abstract on PubMed]

Diverse range of small peptides associated with high-density lipoprotein.
Hortin GL, Shen RF, Martin BM, Remaley AT.
Biochem. Biophys. Res. Commun. 2006 Feb 17;340(3):909-15.
[Text Abstract on PubMed]

The role of exercise in modulating the impact of an ultralow-fat diet on serum lipids and apolipoproteins in patients with or at risk for coronary artery disease.
Marshall DA, Vernalis MN, Remaley AT, Walizer EM, Scally JP, Taylor AJ.
Am. Heart J. 2006 Feb;151(2):484-91.
[Text Abstract on PubMed]

Detection and quantitation of serum mesothelin, a tumor marker for patients with mesothelioma and ovarian cancer.
Hassan R, Remaley AT, Sampson ML, Zhang J, Cox DD, Pingpank J, Alexander R, Willingham M, Pastan I, Onda M.
Clin. Cancer Res. 2006 Jan 15;12(2):447-53.
[Text Abstract on PubMed]

Immunoassay interference by a commonly used blood collection tube additive, the organosilicone surfactant silwet L-720.
Bowen RA, Chan Y, Ruddel ME, Hortin GL, Csako G, Demosky, Remaley AT.
Clin. Chem. 2005 Oct;51(10):1874-82.
[Text Abstract on PubMed]

Tangier disease: still more questions than answers.
Nofer JR, Remaley AT.
Cell. Mol. Life Sci. 2005 Oct;62(19-20):2150-60.
[Text Abstract on PubMed]

Prostate specific antigen as a clinical biomarker for prostate cancer: what's the take home message?
Leach FS, Koh MS, Chan YW, Bark S, Ray R, Morton RA, Remaley AT.
Cancer Biol. Ther. 2005 Apr;4(4):371-5.
[Text Abstract on PubMed]

Serum amyloid A binding to CLA-1 (CD36 and LIMPII analogous-1) mediates serum amyloid A protein-induced activation of ERK1/2 and p38 mitogen-activated protein kinases.
Baranova IN, Vishnyakova TG, Bocharov AV, Kurlander R, Chen Z, Kimelman ML, Remaley AT, Csako G, Thomas F, Eggerman TL, Patterson AP.
J. Biol. Chem. 2005 Mar 4;280(9):8031-40.
[Text Abstract on PubMed]

Effect of blood collection tubes on total triiodothyronine and other laboratory assays.
Bowen RA, Chan Y, Cohen J, Rehak NN, Hortin GL, Csako G, Remaley AT.
Clin. Chem. 2005 Feb;51(2):424-33.
[Text Abstract on PubMed]

Potential interferences from blood collection tubes in mass spectrometric analyses of serum polypeptides.
Drake SK, Bowen RA, Remaley AT, Hortin GL.
Clin. Chem. 2004 Dec;50(12):2398-401.
[Text Abstract on PubMed]

Regulation of plasma high-density lipoprotein levels by the ABCA1 transporter and the emerging role of high-density lipoprotein in the treatment of cardiovascular disease.
Brewer, Remaley AT, Neufeld EB, Basso F, Joyce C.
Arterioscler. Thromb. Vasc. Biol. 2004 Oct;24(10):1755-60.
[Text Abstract on PubMed]

Serum amyloid A promotes ABCA1-dependent and ABCA1-independent lipid efflux from cells.
Stonik JA, Remaley AT, Demosky SJ, Neufeld EB, Bocharov A, Brewer HB.
Biochem. Biophys. Res. Commun. 2004 Sep 3;321(4):936-41.
[Text Abstract on PubMed]

Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS) uptake and LPS-induced pro-inflammatory cytokine responses in THP-1 monocyte cells.
Bocharov AV, Baranova IN, Vishnyakova TG, Remaley AT, Csako G, Thomas F, Patterson AP, Eggerman TL.
J. Biol. Chem. 2004 Aug 20;279(34):36072-82.
[Text Abstract on PubMed]

Rapid intraoperative immunoassay of parathyroid hormone and other hormones: a new paradigm for point-of-care testing.
Sokoll LJ, Wians, Remaley AT.
Clin. Chem. 2004 Jul;50(7):1126-35.
[Text Abstract on PubMed]

The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter.
Freeman LA, Kennedy A, Wu J, Bark S, Remaley AT, Santamarina-Fojo S, Brewer.
J. Lipid Res. 2004 Jul;45(7):1197-206.
[Text Abstract on PubMed]

Ritonavir decreases the nonrenal clearance of digoxin in healthy volunteers with known MDR1 genotypes.
Penzak SR, Shen JM, Alfaro RM, Remaley AT, Natarajan V, Falloon J.
Ther Drug Monit. 2004 Jun;26(3):322-30.
[Text Abstract on PubMed]

The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease.
Neufeld EB, Stonik JA, Demosky, Knapper CL, Combs CA, Cooney A, Comly M, Dwyer N, Blanchette-Mackie J, Remaley AT, Santamarina-Fojo S, Brewer.
J. Biol. Chem. 2004 Apr 9;279(15):15571-8.
[Text Abstract on PubMed]

Phosphorylation and stabilization of ATP binding cassette transporter A1 by synthetic amphiphilic helical peptides.
Arakawa R, Hayashi M, Remaley AT, Brewer BH, Yamauchi Y, Yokoyama S.
J. Biol. Chem. 2004 Feb 20;279(8):6217-20.
[Text Abstract on PubMed]

Automated procedure for improving the RNA isolation step in viral load testing for human immunodeficiency virus.
Xu M, Chan Y, Fischer SH, Remaley AT.
J. Clin. Microbiol. 2004 Jan;42(1):439-40.
[Text Abstract on PubMed]

Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism.
Libutti SK, Crabtree JS, Lorang D, Burns AL, Mazzanti C, Hewitt SM, O'Connor S, Ward JM, Emmert-Buck MR, Remaley A, Miller M, Turner E, Alexander HR, Arnold A, Marx SJ, Collins FS, Spiegel AM.
Cancer Res. 2003 Nov 15;63(22):8022-8.
[Text Abstract on PubMed]

Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1.
Vishnyakova TG, Bocharov AV, Baranova IN, Chen Z, Remaley AT, Csako G, Eggerman TL, Patterson AP.
J. Biol. Chem. 2003 Jun 20;278(25):22771-80.
[Text Abstract on PubMed]

Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway.
Remaley AT, Thomas F, Stonik JA, Demosky SJ, Bark SE, Neufeld EB, Bocharov AV, Vishnyakova TG, Patterson AP, Eggerman TL, Santamarina-Fojo S, Brewer HB.
J. Lipid Res. 2003 Apr;44(4):828-36.
[Text Abstract on PubMed]

Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations.
Basso F, Freeman L, Knapper CL, Remaley A, Stonik J, Neufeld EB, Tansey T, Amar MJ, Fruchart-Najib J, Duverger N, Santamarina-Fojo S, Brewer.
J. Lipid Res. 2003 Feb;44(2):296-302.
[Text Abstract on PubMed]

Utility of rapid intraoperative parathyroid hormone assay to predict severe postoperative hypocalcemia after reoperation for hyperparathyroidism.
Elaraj DM, Remaley AT, Simonds WF, Skarulis MC, Libutti SK, Bartlett DL, Venzon DJ, Marx SJ, Alexander HR.
Surgery. 2002 Dec;132(6):1028-33; discussion 1033-4.
[Text Abstract on PubMed]

The ABCA1 transporter functions on the basolateral surface of hepatocytes.
Neufeld EB, Demosky, Stonik JA, Combs C, Remaley AT, Duverger N, Santamarina-Fojo S, Brewer.
Biochem. Biophys. Res. Commun. 2002 Oct 4;297(4):974-9.
[Text Abstract on PubMed]

Rapid measurement of insulin using the Abbott IMx: application to the management of insulinoma.
Albright SV, McCart JA, Libutti SK, Bartlett DL, Alexander HR, Sampson ML, Ruddel ME, Remaley AT.
Ann. Clin. Biochem. 2002 Sep;39(Pt 5):513-5.
[Text Abstract on PubMed]

Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster.
Remaley AT, Bark S, Walts AD, Freeman L, Shulenin S, Annilo T, Elgin E, Rhodes HE, Joyce C, Dean M, Santamarina-Fojo S, Brewer.
Biochem. Biophys. Res. Commun. 2002 Jul 12;295(2):276-82.
[Text Abstract on PubMed]

Improvement of AMPLICOR human immunodeficiency virus type 1 viral load test (version 1.5) by addition of a coprecipitant during the RNA isolation step.
Xu M, Chan Y, Fischer SH, Remaley AT.
J. Clin. Microbiol. 2002 Jul;40(7):2616-7.
[Text Abstract on PubMed]

Raloxifene, a selective estrogen receptor modulator, induces apoptosis in androgen-responsive human prostate cancer cell line LNCaP through an androgen-independent pathway.
Kim IY, Seong DH, Kim BC, Lee DK, Remaley AT, Leach F, Morton RA, Kim SJ.
Cancer Res. 2002 Jul 1;62(13):3649-53.
[Text Abstract on PubMed]

Flutamide decreases cortisol clearance in patients with congenital adrenal hyperplasia.
Charmandari E, Calis KA, Keil MF, Mohassel MR, Remaley A, Merke DP.
J. Clin. Endocrinol. Metab. 2002 Jul;87(7):3197-200.
[Text Abstract on PubMed]

Controlled study of citrate effects and response to i.v. calcium administration during allogeneic peripheral blood progenitor cell donation.
Bolan CD, Cecco SA, Wesley RA, Horne M, Yau YY, Remaley AT, Childs RW, Barrett AJ, Rehak NN, Leitman SF.
Transfusion. 2002 Jul;42(7):935-46.
[Text Abstract on PubMed]

Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells.
Baranova I, Vishnyakova T, Bocharov A, Chen Z, Remaley AT, Stonik J, Eggerman TL, Patterson AP.
Infect. Immun. 2002 Jun;70(6):2995-3003.
[Text Abstract on PubMed]

Serum thyroxine level and cognitive decline in euthyroid older women.
Volpato S, Guralnik JM, Fried LP, Remaley AT, Cappola AR, Launer LJ.
Neurology. 2002 Apr 9;58(7):1055-61.
[Text Abstract on PubMed]

The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene.
Yang XP, Freeman LA, Knapper CL, Amar MJ, Remaley A, Brewer, Santamarina-Fojo S.
J. Lipid Res. 2002 Feb;43(2):297-306.
[Text Abstract on PubMed]

The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice.
Joyce CW, Amar MJ, Lambert G, Vaisman BL, Paigen B, Najib-Fruchart J, Hoyt, Neufeld ED, Remaley AT, Fredrickson DS, Brewer, Santamarina-Fojo S.
Proc. Natl. Acad. Sci. U.S.A. 2002 Jan 8;99(1):407-12.
[Text Abstract on PubMed]

Regulation and intracellular trafficking of the ABCA1 transporter.
Santamarina-Fojo S, Remaley AT, Neufeld EB, Brewer.
J. Lipid Res. 2001 Sep;42(9):1339-45.
[Text Abstract on PubMed]

Measurement of cholesterol in plasma and other body fluids.
Warnick GR, Remaley AT.
Curr Atheroscler Rep. 2001 Sep;3(5):404-11.
[Text Abstract on PubMed]

Cellular localization and trafficking of the human ABCA1 transporter.
Neufeld EB, Remaley AT, Demosky SJ, Stonik JA, Cooney AM, Comly M, Dwyer NK, Zhang M, Blanchette-Mackie J, Santamarina-Fojo S, Brewer.
J. Biol. Chem. 2001 Jul 20;276(29):27584-90.
[Text Abstract on PubMed]

ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice.
Vaisman BL, Lambert G, Amar M, Joyce C, Ito T, Shamburek RD, Cain WJ, Fruchart-Najib J, Neufeld ED, Remaley AT, Brewer, Santamarina-Fojo S.
J. Clin. Invest. 2001 Jul;108(2):303-9.
[Text Abstract on PubMed]

Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice.
Lambert G, Sakai N, Vaisman BL, Neufeld EB, Marteyn B, Chan CC, Paigen B, Lupia E, Thomas A, Striker LJ, Blanchette-Mackie J, Csako G, Brady JN, Costello R, Striker GE, Remaley AT, Brewer, Santamarina-Fojo S.
J. Biol. Chem. 2001 May 4;276(18):15090-8.
[Text Abstract on PubMed]

A case of spurious hypercalcitoninemia: a cautionary tale on the use of plasma calcitonin assays in the screening of patients with thyroid nodules for neoplasia.
Uwaifo GI, Remaley AT, Stene M, Reynolds JC, Yen PM, Snider RH, Becker KL, Sarlis NJ.
J. Endocrinol. Invest. 2001 May;24(5):361-9.
[Text Abstract on PubMed]

Triple lipid screening test: a homogeneous sequential assay for HDL-cholesterol, total cholesterol, and triglycerides.
Sampson ML, Aubry A, Csako G, Remaley AT.
Clin. Chem. 2001 Mar;47(3):532-9.
[Text Abstract on PubMed]

Apolipoprotein specificity for lipid efflux by the human ABCAI transporter.
Remaley AT, Stonik JA, Demosky SJ, Neufeld EB, Bocharov AV, Vishnyakova TG, Eggerman TL, Patterson AP, Duverger NJ, Santamarina-Fojo S, Brewer.
Biochem. Biophys. Res. Commun. 2001 Jan 26;280(3):818-23.
[Text Abstract on PubMed]

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.
Chinetti G, Lestavel S, Bocher V, Remaley AT, Neve B, Torra IP, Teissier E, Minnich A, Jaye M, Duverger N, Brewer HB, Fruchart JC, Clavey V, Staels B.
Nat. Med. 2001 Jan;7(1):53-8.
[Text Abstract on PubMed]

An ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamily maps to human chromosome 2p21 in the region of the Sitosterolemia locus.
Shulenin S, Schriml LM, Remaley AT, Fojo S, Brewer B, Allikmets R, Dean M.
Cytogenet. Cell Genet. 2001;92(3-4):204-8.
[Text Abstract on PubMed]

Heat shock protein 60 is a high-affinity high-density lipoprotein binding protein.
Bocharov AV, Vishnyakova TG, Baranova IN, Remaley AT, Patterson AP, Eggerman TL.
Biochem. Biophys. Res. Commun. 2000 Oct 14;277(1):228-35.
[Text Abstract on PubMed]

Rapid intraoperative cortisol assay: design and utility for localizing adrenal tumors by venous sampling.
Woods JJ, Sampson ML, Ruddel ME, Remaley AT.
Clin. Biochem. 2000 Aug;33(6):501-3.
[Text Abstract on PubMed]

Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter.
Santamarina-Fojo S, Peterson K, Knapper C, Qiu Y, Freeman L, Cheng JF, Osorio J, Remaley A, Yang XP, Haudenschild C, Prades C, Chimini G, Blackmon E, Francois T, Duverger N, Rubin EM, Rosier M, Denèfle P, Fredrickson DS, Brewer.
Proc. Natl. Acad. Sci. U.S.A. 2000 Jul 5;97(14):7987-92.
[Text Abstract on PubMed]

Dual HDL/total cholesterol test: a single-tube, homogeneous assay for sequential measurement of HDL cholesterol and total cholesterol.
Sampson ML, Csako G, Remaley AT.
Ann. Clin. Biochem. 2000 Jul;37 ( Pt 4):479-87.
[Text Abstract on PubMed]

Estimation of serum apolipoprotein B by a modified homogeneous assay for HDL-cholesterol.
Sampson ML, Csako G, Remaley AT.
Clin. Chem. 2000 Jun;46(6 Pt 1):869-71.
[Text Abstract on PubMed]

Increased levothyroxine requirements presenting as "inappropriate" TSH secretion syndrome in a patient with nephrotic syndrome.
Collins MT, Remaley AT, Csako G, Pucino F, Skarulis MC, Balow JE, Sarlis NJ.
J. Endocrinol. Invest. 2000 Jun;23(6):383-92.
[Text Abstract on PubMed]

Limitations on the quantitative determination of telomerase activity by the electrophoretic and ELISA based TRAP assays.
Wu YY, Hruszkewycz AM, Delgado RM, Yang A, Vortmeyer AO, Moon YW, Weil RJ, Zhuang Z, Remaley AT.
Clin. Chim. Acta. 2000 Mar;293(1-2):199-212.
[Text Abstract on PubMed]

Sensitive immunoassay of tissue cell proteins procured by laser capture microdissection.
Simone NL, Remaley AT, Charboneau L, Petricoin, Glickman JW, Emmert-Buck MR, Fleisher TA, Liotta LA.
Am. J. Pathol. 2000 Feb;156(2):445-52.
[Text Abstract on PubMed]

Pressure cycling technology: a novel approach to virus inactivation in plasma.
Bradley DW, Hess RA, Tao F, Sciaba-Lentz L, Remaley AT, Laugharn, Manak M.
Transfusion. 2000 Feb;40(2):193-200.
[Text Abstract on PubMed]

Kinetic analysis of the rapid intraoperative parathyroid hormone assay in patients during operation for hyperparathyroidism.
Libutti SK, Alexander HR, Bartlett DL, Sampson ML, Ruddel ME, Skarulis M, Marx SJ, Spiegel AM, Simmonds W, Remaley AT.
Surgery. 1999 Dec;126(6):1145-50; discussion 1150-1.
[Text Abstract on PubMed]

Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred.
Remaley AT, Rust S, Rosier M, Knapper C, Naudin L, Broccardo C, Peterson KM, Koch C, Arnould I, Prades C, Duverger N, Funke H, Assman G, Dinger M, Dean M, Chimini G, Santamarina-Fojo S, Fredrickson DS, Denefle P, Brewer.
Proc. Natl. Acad. Sci. U.S.A. 1999 Oct 26;96(22):12685-90.
[Text Abstract on PubMed]

Cubilin, the endocytic receptor for intrinsic factor-vitamin B(12) complex, mediates high-density lipoprotein holoparticle endocytosis.
Hammad SM, Stefansson S, Twal WO, Drake CJ, Fleming P, Remaley A, Brewer, Argraves WS.
Proc. Natl. Acad. Sci. U.S.A. 1999 Aug 31;96(18):10158-63.
[Text Abstract on PubMed]

Prevalence-value-accuracy plots: a new method for comparing diagnostic tests based on misclassification costs.
Remaley AT, Sampson ML, DeLeo JM, Remaley NA, Farsi BD, Zweig MH.
Clin. Chem. 1999 Jul;45(7):934-41.
[Text Abstract on PubMed]

The differential effect of food intake and beta-adrenergic stimulation on adipose-derived hormones and cytokines in man.
Orban Z, Remaley AT, Sampson M, Trajanoski Z, Chrousos GP.
J. Clin. Endocrinol. Metab. 1999 Jun;84(6):2126-33.
[Text Abstract on PubMed]

Point-of-care testing of parathyroid hormone during the surgical treatment of hyperparathyroidism.
Remaley AT, Woods JJ, Glickman JW.
MLO Med Lab Obs. 1999 Apr;31(4):20-4, 26-7; quiz 28-30.
[Text Abstract on PubMed]

Telomerase activity in microdissected human gliomas.
Weil RJ, Wu YY, Vortmeyer AO, Moon YW, Delgado RM, Fuller BG, Lonser RR, Remaley AT, Zhuang Z.
Mod. Pathol. 1999 Jan;12(1):41-6.
[Text Abstract on PubMed]

Differential rate of cholesterol efflux from the apical and basolateral membranes of MDCK cells.
Remaley AT, Farsi BD, Shirali AC, Hoeg JM, Brewer.
J. Lipid Res. 1998 Jun;39(6):1231-8.
[Text Abstract on PubMed]

In vivo kinetics as a sensitive method for testing physiologically intact human recombinant apolipoprotein A-I: comparison of three different expression systems.
Schmidt HH, Haas RE, Remaley A, Genschel J, Strassburg CP, Büttner C, Manns MP.
Clin. Chim. Acta. 1997 Dec 10;268(1-2):41-60.
[Text Abstract on PubMed]

Decreased reverse cholesterol transport from Tangier disease fibroblasts. Acceptor specificity and effect of brefeldin on lipid efflux.
Remaley AT, Schumacher UK, Stonik JA, Farsi BD, Nazih H, Brewer.
Arterioscler. Thromb. Vasc. Biol. 1997 Sep;17(9):1813-21.
[Text Abstract on PubMed]

High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase.
Bérard AM, Föger B, Remaley A, Shamburek R, Vaisman BL, Talley G, Paigen B, Hoyt, Marcovina S, Brewer, Santamarina-Fojo S.
Nat. Med. 1997 Jul;3(7):744-9.
[Text Abstract on PubMed]

Carboxyl-terminal domain truncation alters apolipoprotein A-I in vivo catabolism.
Schmidt HH, Remaley AT, Stonik JA, Ronan R, Wellmann A, Thomas F, Zech LA, Brewer, Hoeg JM.
J. Biol. Chem. 1995 Mar 10;270(10):5469-75.
[Text Abstract on PubMed]

Polarized secretion of apoA-I and apoA-II by transfected MDCK cells.
Remaley AT, Hoeg JM.
J. Lipid Res. 1995 Mar;36(3):407-13.
[Text Abstract on PubMed]

Identification of novel differentially expressed hepatic genes in cholesterol-fed rabbits by a non-targeted gene approach.
Remaley AT, Schumacher UK, Amouzadeh HR, Brewer, Hoeg JM.
J. Lipid Res. 1995 Feb;36(2):308-14.
[Text Abstract on PubMed]

O-linked glycosylation modifies the association of apolipoprotein A-II to high density lipoproteins.
Remaley AT, Wong AW, Schumacher UK, Meng MS, Brewer, Hoeg JM.
J. Biol. Chem. 1993 Mar 25;268(9):6785-90.
[Text Abstract on PubMed]

N-linked glycosylation of rabies virus glycoprotein. Individual sequons differ in their glycosylation efficiencies and influence on cell surface expression.
Shakin-Eshleman SH, Remaley AT, Eshleman JR, Wunner WH, Spitalnik SL.
J. Biol. Chem. 1992 May 25;267(15):10690-8.
[Text Abstract on PubMed]

Expression of human glycophorin A in wild type and glycosylation-deficient Chinese hamster ovary cells. Role of N- and O-linked glycosylation in cell surface expression.
Remaley AT, Ugorski M, Wu N, Litzky L, Burger SR, Moore JS, Fukuda M, Spitalnik SL.
J. Biol. Chem. 1991 Dec 15;266(35):24176-83.
[Text Abstract on PubMed]

Stable expression of rabies virus glycoprotein in Chinese hamster ovary cells.
Burger SR, Remaley AT, Danley JM, Moore J, Muschel RJ, Wunner WH, Spitalnik SL.
J. Gen. Virol. 1991 Feb;72 ( Pt 2):359-67.
[Text Abstract on PubMed]

Markedly increased concentrations of ferritin in an AIDS patient with disseminated histoplasmosis.
Remaley AT, Goodman DB.
Clin. Chem. 1990 Nov;36(11):1992-3.
[Text Abstract on PubMed]

Macroenzymes: biochemical characterization, clinical significance, and laboratory detection.
Remaley AT, Wilding P.
Clin. Chem. 1989 Dec;35(12):2261-70.
[Text Abstract on PubMed]

Evaluation of the clinical utility of platelet aggregation studies.
Remaley AT, Kennedy JM, Laposata M.
Am. J. Hematol. 1989 Jul;31(3):188-93.
[Text Abstract on PubMed]

Discordant hCG measurements in a patient with a carcinoma.
Remaley AT, Bulley M, Senior MB, Goodman DB.
Clin. Chem. 1989 Jun;35(6):1259-60.
[Text Abstract on PubMed]

Biochemistry of the Leishmania species.
Glew RH, Saha AK, Das S, Remaley AT.
Microbiol. Rev. 1988 Dec;52(4):412-32.
[Text Abstract on PubMed]

Laboratory assessment of poisoning with a carbamate insecticide.
Remaley AT, Hicks DG, Kane MD, Shaw LM.
Clin. Chem. 1988 Sep;34(9):1933-6.
[Text Abstract on PubMed]

Hydrolysis of phosphoproteins and inositol phosphates by cell surface phosphatase of Leishmania donovani.
Das S, Saha AK, Remaley AT, Glew RH, Dowling JN, Kajiyoshi M, Gottlieb M.
Mol. Biochem. Parasitol. 1986 Aug;20(2):143-53.
[Text Abstract on PubMed]

Leishmania donovani: surface membrane acid phosphatase blocks neutrophil oxidative metabolite production.
Remaley AT, Glew RH, Kuhns DB, Basford RE, Waggoner AS, Ernst LA, Pope M.
Exp. Parasitol. 1985 Dec;60(3):331-41.
[Text Abstract on PubMed]

Properties of an acid phosphatase from Legionella micdadei which blocks superoxide anion production by human neutrophils.
Saha AK, Dowling JN, LaMarco KL, Das S, Remaley AT, Olomu N, Pope MT, Glew RH.
Arch. Biochem. Biophys. 1985 Nov 15;243(1):150-60.
[Text Abstract on PubMed]

Lysosomal storage diseases.
Glew RH, Basu A, Prence EM, Remaley AT.
Lab. Invest. 1985 Sep;53(3):250-69.
[Text Abstract on PubMed]

Characterization of Leishmania donovani acid phosphatases.
Remaley AT, Das S, Campbell PI, LaRocca GM, Pope MT, Glew RH.
J. Biol. Chem. 1985 Jan 25;260(2):880-6.
[Text Abstract on PubMed]

Leishmanial phosphatase blocks neutrophil O-2 production.
Remaley AT, Kuhns DB, Basford RE, Glew RH, Kaplan SS.
J. Biol. Chem. 1984 Sep 25;259(18):11173-5.
[Text Abstract on PubMed]

Brevianamides A and B Are Formed Only After Conidiation Has Begun in Solid Cultures of Penicillium brevicompactum.
Bird BA, Remaley AT, Campbell IM.
Appl. Environ. Microbiol. 1981 Sep;42(3):521-5.
[Text Abstract on PubMed]

Mycophenolic Acid Production by Penicillium brevicompactum on Solid Media.
Bartman CD, Doerfler DL, Bird BA, Remaley AT, Peace JN, Campbell IM.
Appl. Environ. Microbiol. 1981 Mar;41(3):729-36.
[Text Abstract on PubMed]