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Elizabeth Murphy, Ph.D.


Principal Investigator thumbnail image

Elizabeth Murphy
Senior Investigator

P: +1 301 496 5828
F: +1 301 402 0190

Full Publications Listing

Cyclophilin D Modulates the Mitochondrial Acetylome.
Nguyen TT, Wong RP, Menazza S, Sun J, Chen Y, Wang G, Gucek M, Steenbergen C, Sack MN, Murphy E.
Circ Res..
[Text Abstract on PubMed]

Optical spectroscopy in turbid media utilizing an integrating sphere: mitochondrial chromophore analysis during metabolic transitions.
Chess DJ, Billings E, Covian R, Glancy B, French S, Taylor J, Bari HD, Murphy E, Balaban RS.
Anal Biochem..
[Text Abstract on PubMed]

CypD(-/-) hearts have altered levels of proteins involved in Krebs cycle, branch chain amino acid degradation and pyruvate metabolism.
Menazza S, Wong R, Nguyen T, Wang G, Gucek M, Murphy E.
J Mol Cell Cardiol. 2013 Mar;56:81-90.
[Text Abstract on PubMed]

The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T.
Nature. 2012 Dec 13;492(7428):199-204.
[Text Abstract on PubMed]

S-nitrosylation: Specificity, Occupancy, and Interaction with Other Post-translational Modifications.
Evangelista AM, Kohr MJ, Murphy E.
Antioxid. Redox Signal. 2012 Nov 19.
[Text Abstract on PubMed]

Measurement of s-nitrosylation occupancy in the myocardium with cysteine-reactive tandem mass tags: short communication.
Kohr MJ, Aponte A, Sun J, Gucek M, Steenbergen C, Murphy E.
Circ. Res. 2012 Oct 26;111(10):1308-12.
[Text Abstract on PubMed]

Essential role of nitric oxide in acute ischemic preconditioning: S-Nitros(yl)ation versus sGC/cGMP/PKG signaling?
Sun J, Aponte AM, Kohr MJ, Tong G, Steenbergen C, Murphy E.
Free Radic. Biol. Med. 2012 Sep 16.
[Text Abstract on PubMed]

Nuclear miRNA regulates the mitochondrial genome in the heart.
Das S, Ferlito M, Kent OA, Fox-Talbot K, Wang R, Liu D, Raghavachari N, Yang Y, Wheelan SJ, Murphy E, Steenbergen C.
Circ. Res. 2012 Jun 8;110(12):1596-603.
[Text Abstract on PubMed]

Acute inhibition of GSK causes mitochondrial remodeling.
Nguyen T, Wong R, Wang G, Gucek M, Steenbergen C, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2012 Jun 1;302(11):H2439-45.
[Text Abstract on PubMed]

Does the voltage dependent anion channel modulate cardiac ischemia-reperfusion injury?
Das S, Steenbergen C, Murphy E.
Biochim. Biophys. Acta. 2012 Jun;1818(6):1451-6.
[Text Abstract on PubMed]

S-nitrosylation: a radical way to protect the heart.
Murphy E, Kohr M, Sun J, Nguyen T, Steenbergen C.
J. Mol. Cell. Cardiol. 2012 Mar;52(3):568-77.
[Text Abstract on PubMed]

Disruption of caveolae blocks ischemic preconditioning-mediated S-nitrosylation of mitochondrial proteins.
Sun J, Kohr MJ, Nguyen T, Aponte AM, Connelly PS, Esfahani SG, Gucek M, Daniels MP, Steenbergen C, Murphy E.
Antioxid. Redox Signal. 2012 Jan 1;16(1):45-56.
[Text Abstract on PubMed]

Mitochondrial permeability transition pore and calcium handling.
Wong R, Steenbergen C, Murphy E.
Methods Mol. Biol. 2012;810:235-42.
[Text Abstract on PubMed]

Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore.
Nguyen TT, Stevens MV, Kohr M, Steenbergen C, Sack MN, Murphy E.
J. Biol. Chem. 2011 Nov 18;286(46):40184-92.
[Text Abstract on PubMed]

Myristoylated methionine sulfoxide reductase A protects the heart from ischemia-reperfusion injury.
Zhao H, Sun J, Deschamps AM, Kim G, Liu C, Murphy E, Levine RL.
Am. J. Physiol. Heart Circ. Physiol. 2011 Oct;301(4):H1513-8.
[Text Abstract on PubMed]

New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop.
Schwartz Longacre L, Kloner RA, Arai AE, Baines CP, Bolli R, Braunwald E, Downey J, Gibbons RJ, Gottlieb RA, Heusch G, Jennings RB, Lefer DJ, Mentzer RM, Murphy E, Ovize M, Ping P, Przyklenk K, Sack MN, Vander Heide RS, Vinten-Johansen J, Yellon DM, National Heart, Lung, and Blood Institute, National Institutes of Health.
Circulation. 2011 Sep 6;124(10):1172-9.
[Text Abstract on PubMed]

Estrogen signaling and cardiovascular disease.
Murphy E.
Circ. Res. 2011 Sep 2;109(6):687-96.
[Text Abstract on PubMed]

The role of comorbidities in cardioprotection.
Sack MN, Murphy E.
J. Cardiovasc. Pharmacol. Ther. 2011 Sep-Dec;16(3-4):267-72.
[Text Abstract on PubMed]

What makes the mitochondria a killer? Can we condition them to be less destructive?
Murphy E, Steenbergen C.
Biochim. Biophys. Acta. 2011 Jul;1813(7):1302-8.
[Text Abstract on PubMed]

Characterization of potential S-nitrosylation sites in the myocardium.
Kohr MJ, Aponte AM, Sun J, Wang G, Murphy E, Gucek M, Steenbergen C.
Am. J. Physiol. Heart Circ. Physiol. 2011 Apr;300(4):H1327-35.
[Text Abstract on PubMed]

Mechanism of cardioprotection: what can we learn from females?
Murphy E, Lagranha C, Deschamps A, Kohr M, Nguyen T, Wong R, Sun J, Steenbergen C.
Pediatr Cardiol. 2011 Mar;32(3):354-9.
[Text Abstract on PubMed]

Simultaneous measurement of protein oxidation and S-nitrosylation during preconditioning and ischemia/reperfusion injury with resin-assisted capture.
Kohr MJ, Sun J, Aponte A, Wang G, Gucek M, Murphy E, Steenbergen C.
Circ. Res. 2011 Feb 18;108(4):418-26.
[Text Abstract on PubMed]

What can we learn about cardioprotection from the cardiac mitochondrial proteome?
Gucek M, Murphy E.
Cardiovasc. Res. 2010 Nov 1;88(2):211-8.
[Text Abstract on PubMed]

Calcium-sensing receptor: a sensor and mediator of ischemic preconditioning in the heart.
Sun J, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2010 Nov;299(5):H1309-17.
[Text Abstract on PubMed]

Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1.
Lynn EG, Stevens MV, Wong RP, Carabenciov D, Jacobson J, Murphy E, Sack MN.
J. Mol. Cell. Cardiol. 2010 Oct;49(4):693-8.
[Text Abstract on PubMed]

Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice.
Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD.
J. Clin. Invest. 2010 Oct;120(10):3680-7.
[Text Abstract on PubMed]

Regulation of myocyte contraction via neuronal nitric oxide synthase: role of ryanodine receptor S-nitrosylation.
Wang H, Viatchenko-Karpinski S, Sun J, Györke I, Benkusky NA, Kohr MJ, Valdivia HH, Murphy E, Györke S, Ziolo MT.
J. Physiol. (Lond.). 2010 Aug 1;588(Pt 15):2905-17.
[Text Abstract on PubMed]

Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females.
Lagranha CJ, Deschamps A, Aponte A, Steenbergen C, Murphy E.
Circ. Res. 2010 Jun 11;106(11):1681-91.
[Text Abstract on PubMed]

Estrogen receptor activation and cardioprotection in ischemia reperfusion injury.
Deschamps AM, Murphy E, Sun J.
Trends Cardiovasc. Med. 2010 Apr;20(3):73-8.
[Text Abstract on PubMed]

Protein S-nitrosylation and cardioprotection.
Sun J, Murphy E.
Circ. Res. 2010 Feb 5;106(2):285-96.
[Text Abstract on PubMed]

Cardioprotection leads to novel changes in the mitochondrial proteome.
Wong R, Aponte AM, Steenbergen C, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2010 Jan;298(1):H75-91.
[Text Abstract on PubMed]

Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats.
Deschamps AM, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2009 Nov;297(5):H1806-13.
[Text Abstract on PubMed]

Effect of p38 MAP kinases on contractility and ischemic injury in intact heart.
Cross HR, Li M, Petrich BG, Murphy E, Wang Y, Steenbergen C.
Acta Physiol Hung. 2009 Sep;96(3):307-23.
[Text Abstract on PubMed]

Estrogen receptor-beta activation results in S-nitrosylation of proteins involved in cardioprotection.
Lin J, Steenbergen C, Murphy E, Sun J.
Circulation. 2009 Jul 21;120(3):245-54.
[Text Abstract on PubMed]

Mitochondria: from basic biology to cardiovascular disease.
Murphy E, Bers D, Rizzuto R.
J. Mol. Cell. Cardiol. 2009 Jun;46(6):765-6.
[Text Abstract on PubMed]

Cardioprotection and altered mitochondrial adenine nucleotide transport.
Steenbergen C, Das S, Su J, Wong R, Murphy E.
Basic Res. Cardiol. 2009 Mar;104(2):149-56.
[Text Abstract on PubMed]

The regulation and control of mitochondrial homeostasis in changing cardiac tolerance to ischemia-reperfusion injury: a focused issue.
Sack MN, Murphy E, Schulz R.
Basic Res. Cardiol. 2009 Mar;104(2):111-2.
[Text Abstract on PubMed]

Regulation of intracellular and mitochondrial sodium in health and disease.
Murphy E, Eisner DA.
Circ. Res. 2009 Feb 13;104(3):292-303.
[Text Abstract on PubMed]

Why did the NHE inhibitor clinical trials fail?
Murphy E, Allen DG.
J. Mol. Cell. Cardiol. 2009 Feb;46(2):137-41.
[Text Abstract on PubMed]

Does inhibition of glycogen synthase kinase protect in mice?
Murphy E, Steenbergen C.
Circ. Res. 2008 Aug 1;103(3):226-8.
[Text Abstract on PubMed]

Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury.
Murphy E, Steenbergen C.
Physiol. Rev. 2008 Apr;88(2):581-609.
[Text Abstract on PubMed]

Ion transport and energetics during cell death and protection.
Murphy E, Steenbergen C.
Physiology (Bethesda). 2008 Apr;23:115-23.
[Text Abstract on PubMed]

Estrogen-enhanced gene expression of lipoprotein lipase in heart is antagonized by progesterone.
Liu D, Deschamps A, Korach KS, Murphy E.
Endocrinology. 2008 Feb;149(2):711-6.
[Text Abstract on PubMed]

Cardioprotection in females: a role for nitric oxide and altered gene expression.
Murphy E, Steenbergen C.
Heart Fail Rev. 2007 Dec;12(3-4):293-300.
[Text Abstract on PubMed]

Preconditioning results in S-nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport.
Sun J, Morgan M, Shen RF, Steenbergen C, Murphy E.
Circ. Res. 2007 Nov 26;101(11):1155-63.
[Text Abstract on PubMed]

Gender-based differences in mechanisms of protection in myocardial ischemia-reperfusion injury.
Murphy E, Steenbergen C.
Cardiovasc. Res. 2007 Aug 1;75(3):478-86.
[Text Abstract on PubMed]

The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload.
Huss JM, Imahashi K, Dufour CR, Weinheimer CJ, Courtois M, Kovacs A, Giguère V, Murphy E, Kelly DP.
Cell Metab. 2007 Jul;6(1):25-37.
[Text Abstract on PubMed]

Overexpression of the Na+/H+ exchanger and ischemia-reperfusion injury in the myocardium.
Imahashi K, Mraiche F, Steenbergen C, Murphy E, Fliegel L.
Am. J. Physiol. Heart Circ. Physiol. 2007 May;292(5):H2237-47.
[Text Abstract on PubMed]

Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues.
Delozier TC, Kissling GE, Coulter SJ, Dai D, Foley JF, Bradbury JA, Murphy E, Steenbergen C, Zeldin DC, Goldstein JA.
Drug Metab. Dispos. 2007 Apr;35(4):682-8.
[Text Abstract on PubMed]

Treatment with an estrogen receptor-beta-selective agonist is cardioprotective.
Nikolic I, Liu D, Bell JA, Collins J, Steenbergen C, Murphy E.
J. Mol. Cell. Cardiol. 2007 Apr;42(4):769-80.
[Text Abstract on PubMed]

Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration.
Shiva S, Huang Z, Grubina R, Sun J, Ringwood LA, MacArthur PH, Xu X, Murphy E, Darley-Usmar VM, Gladwin MT.
Circ. Res. 2007 Mar 16;100(5):654-61.
[Text Abstract on PubMed]

Preconditioning: the mitochondrial connection.
Murphy E, Steenbergen C.
Annu. Rev. Physiol. 2007;69:51-67.
[Text Abstract on PubMed]

How does endothelin-1 cause a sustained increase in intracellular sodium and calcium which lead to hypertrophy?
Murphy E, Eisner DA.
J. Mol. Cell. Cardiol. 2006 Nov;41(5):782-4.
[Text Abstract on PubMed]

S-nitrosylation: NO-related redox signaling to protect against oxidative stress.
Sun J, Steenbergen C, Murphy E.
Antioxid. Redox Signal. 2006 Sep-Oct;8(9-10):1693-705.
[Text Abstract on PubMed]

Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function.
Seubert JM, Sinal CJ, Graves J, DeGraff LM, Bradbury JA, Lee CR, Goralski K, Carey MA, Luria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, Zeldin DC.
Circ. Res. 2006 Aug 18;99(4):442-50.
[Text Abstract on PubMed]

Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury.
Sun J, Picht E, Ginsburg KS, Bers DM, Steenbergen C, Murphy E.
Circ. Res. 2006 Feb 17;98(3):403-11.
[Text Abstract on PubMed]

Actions of estrogen and estrogen receptors in nonclassical target tissues.
Murphy E, Korach KS.
Ernst Schering Found Symp Proc. 2006(1):13-24.
[Text Abstract on PubMed]

Protein kinase C and preconditioning: role of the sarcoplasmic reticulum.
Yamamura K, Steenbergen C, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2005 Dec;289(6):H2484-90.
[Text Abstract on PubMed]

Mitochondrial dysfunction and apoptosis underlie the pathogenic process in alpha-B-crystallin desmin-related cardiomyopathy.
Maloyan A, Sanbe A, Osinska H, Westfall M, Robinson D, Imahashi K, Murphy E, Robbins J.
Circulation. 2005 Nov 29;112(22):3451-61.
[Text Abstract on PubMed]

Bcl-2 regulation of mitochondrial energetics.
Murphy E, Imahashi K, Steenbergen C.
Trends Cardiovasc. Med. 2005 Nov;15(8):283-90.
[Text Abstract on PubMed]

Cardiac-specific ablation of the Na+-Ca2+ exchanger confers protection against ischemia/reperfusion injury.
Imahashi K, Pott C, Goldhaber JI, Steenbergen C, Philipson KD, Murphy E.
Circ. Res. 2005 Oct 28;97(9):916-21.
[Text Abstract on PubMed]

Mechanisms of erythropoietin-mediated cardioprotection during ischemia-reperfusion injury: role of protein kinase C and phosphatidylinositol 3-kinase signaling.
Hanlon PR, Fu P, Wright GL, Steenbergen C, Arcasoy MO, Murphy E.
FASEB J. 2005 Aug;19(10):1323-5.
[Text Abstract on PubMed]

The role of beta-adrenergic receptor signaling in cardioprotection.
Tong H, Bernstein D, Murphy E, Steenbergen C.
FASEB J. 2005 Jun;19(8):983-5.
[Text Abstract on PubMed]

Inhibition of GSK-3beta as a target for cardioprotection: the importance of timing, location, duration and degree of inhibition.
Murphy E, Steenbergen C.
Expert Opin. Ther. Targets. 2005 Jun;9(3):447-56.
[Text Abstract on PubMed]

Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats.
Howden R, Hanlon PR, Petranka JG, Kleeberger S, Bucher J, Dunnick J, Nyska A, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2005 May;288(5):H2219-24.
[Text Abstract on PubMed]

Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy.
Skavdahl M, Steenbergen C, Clark J, Myers P, Demianenko T, Mao L, Rockman HA, Korach KS, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2005 Feb;288(2):H469-76.
[Text Abstract on PubMed]

Acute hemorrhagic myocardial necrosis and sudden death of rats exposed to a combination of ephedrine and caffeine.
Nyska A, Murphy E, Foley JF, Collins BJ, Petranka J, Howden R, Hanlon P, Dunnick JK.
Toxicol. Sci. 2005 Feb;83(2):388-96.
[Text Abstract on PubMed]

Estrogen receptor beta mediates gender differences in ischemia/reperfusion injury.
Gabel SA, Walker VR, London RE, Steenbergen C, Korach KS, Murphy E.
J. Mol. Cell. Cardiol. 2005 Feb;38(2):289-97.
[Text Abstract on PubMed]

Transgenic expression of Bcl-2 modulates energy metabolism, prevents cytosolic acidification during ischemia, and reduces ischemia/reperfusion injury.
Imahashi K, Schneider MD, Steenbergen C, Murphy E.
Circ. Res. 2004 Oct 1;95(7):734-41.
[Text Abstract on PubMed]

Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway.
Seubert J, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman J, Mao L, Rockman HA, Hammock BD, Murphy E, Zeldin DC.
Circ. Res. 2004 Sep 3;95(5):506-14.
[Text Abstract on PubMed]

Male/female differences in intracellular Na+ regulation during ischemia/reperfusion in mouse heart.
Imahashi K, London RE, Steenbergen C, Murphy E.
J. Mol. Cell. Cardiol. 2004 Sep;37(3):747-53.
[Text Abstract on PubMed]

Erythropoietin receptor expression in adult rat cardiomyocytes is associated with an acute cardioprotective effect for recombinant erythropoietin during ischemia-reperfusion injury.
Wright GL, Hanlon P, Amin K, Steenbergen C, Murphy E, Arcasoy MO.
FASEB J. 2004 Jun;18(9):1031-3.
[Text Abstract on PubMed]

Inhibit GSK-3beta or there's heartbreak dead ahead.
Murphy E.
J. Clin. Invest. 2004 Jun;113(11):1526-8.
[Text Abstract on PubMed]

G protein-coupled receptor internalization signaling is required for cardioprotection in ischemic preconditioning.
Tong H, Rockman HA, Koch WJ, Steenbergen C, Murphy E.
Circ. Res. 2004 Apr 30;94(8):1133-41.
[Text Abstract on PubMed]

Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes.
Shiraishi I, Melendez J, Ahn Y, Skavdahl M, Murphy E, Welch S, Schaefer E, Walsh K, Rosenzweig A, Torella D, Nurzynska D, Kajstura J, Leri A, Anversa P, Sussman MA.
Circ. Res. 2004 Apr 16;94(7):884-91.
[Text Abstract on PubMed]

Primary and secondary signaling pathways in early preconditioning that converge on the mitochondria to produce cardioprotection.
Murphy E.
Circ. Res. 2004 Jan 9;94(1):7-16.
[Text Abstract on PubMed]

Serum troponins as biomarkers of drug-induced cardiac toxicity.
Wallace KB, Hausner E, Herman E, Holt GD, MacGregor JT, Metz AL, Murphy E, Rosenblum IY, Sistare FD, York MJ.
Toxicol Pathol. 2004 Jan-Feb;32(1):106-21.
[Text Abstract on PubMed]

Gender differences in sarcoplasmic reticulum calcium loading after isoproterenol.
Chen J, Petranka J, Yamamura K, London RE, Steenbergen C, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2003 Dec;285(6):H2657-62.
[Text Abstract on PubMed]

Inhibition of delta-protein kinase C protects against reperfusion injury of the ischemic heart in vivo.
Inagaki K, Chen L, Ikeno F, Lee FH, Imahashi K, Bouley DM, Rezaee M, Yock PG, Murphy E, Mochly-Rosen D.
Circulation. 2003 Nov 11;108(19):2304-7.
[Text Abstract on PubMed]

Preconditioning: is the Akt-ion in the PI3K pathway?
Murphy E, Tong H, Steenbergen C.
J. Mol. Cell. Cardiol. 2003 Sep;35(9):1021-5.
[Text Abstract on PubMed]

Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes.
Wright G, Higgin JJ, Raines RT, Steenbergen C, Murphy E.
J. Biol. Chem. 2003 May 30;278(22):20235-9.
[Text Abstract on PubMed]

Ablation of PLB exacerbates ischemic injury to a lesser extent in female than male mice: protective role of NO.
Cross HR, Kranias EG, Murphy E, Steenbergen C.
Am. J. Physiol. Heart Circ. Physiol. 2003 Feb;284(2):H683-90.
[Text Abstract on PubMed]

Alterations in apoptotic signaling in human idiopathic cardiomyopathic hearts in failure.
Steenbergen C, Afshari CA, Petranka JG, Collins J, Martin K, Bennett L, Haugen A, Bushel P, Murphy E.
Am. J. Physiol. Heart Circ. Physiol. 2003 Jan;284(1):H268-76.
[Text Abstract on PubMed]

Is Na/Ca exchange during ischemia and reperfusion beneficial or detrimental?
Murphy E, Cross HR, Steenbergen C.
Ann. N. Y. Acad. Sci. 2002 Nov;976:421-30.
[Text Abstract on PubMed]

Overexpression of A(3) adenosine receptors decreases heart rate, preserves energetics, and protects ischemic hearts.
Cross HR, Murphy E, Black RG, Auchampach J, Steenbergen C.
Am. J. Physiol. Heart Circ. Physiol. 2002 Oct;283(4):H1562-8.
[Text Abstract on PubMed]