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Caroline Fox, M.D., M.P.H.

Publications


Principal Investigator thumbnail image

Caroline Fox
Senior Investigator

P: 508-935-3447
F: 508-872-2678
caroline.fox@nih.gov


Full Publications Listing

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.
Graff M, Ngwa JS, Workalemahu T, Homuth G, Schipf S, Teumer A, Völzke H, Wallaschofski H, Abecasis GR, Edward L, Francesco C, Sanna S, Scheet P, Schlessinger D, Sidore C, Xiao X, Wang Z, Chanock SJ, Jacobs KB, Hayes RB, Hu F, Van Dam RM, null null, Crout RJ, Marazita ML, Shaffer JR, Atwood LD, Fox CS, Heard-Costa NL, White C, Choh AC, Czerwinski SA, Demerath EW, Dyer TD, Towne B, Amin N, Oostra BA, Van Duijn CM, Zillikens MC, Esko T, Nelis M, Nikopensius T, Metspalu A, Strachan DP, Monda K, Qi L, North KE, Cupples LA, Gordon-Larsen P, Berndt SI.
Hum Mol Genet. 2013 Jun 5.
[Text Abstract on PubMed]

A Combined Epidemiologic and Metabolomic Approach Improves CKD Prediction.
Rhee EP, Clish CB, Ghorbani A, Larson MG, Elmariah S, McCabe E, Yang Q, Cheng S, Pierce K, Deik A, Souza AL, Farrell L, Domos C, Yeh RW, Palacios I, Rosenfield K, Vasan RS, Florez JC, Wang TJ, Fox CS, Gerszten RE.
J Am Soc Nephrol. 2013 May 16.
[Text Abstract on PubMed]

Distribution, determinants, and normal reference values of thoracic and abdominal aortic diameters by computed tomography (from the Framingham Heart Study).
Rogers IS, Massaro JM, Truong QA, Mahabadi AA, Kriegel MF, Fox CS, Thanassoulis G, Isselbacher EM, Hoffmann U, O'Donnell CJ.
Am J Cardiol. 2013 May 15;111(10):1510-6.
[Text Abstract on PubMed]

Genetic variation associated with circulating monocyte count in the eMERGE Network.
Crosslin DR, McDavid A, Weston N, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF, Pugh E, Kho A, Hayes MG, Ritchie MD, Saip A, Crawford DC, Crane PK, Newton K, Carrell DS, Gallego CJ, Nalls MA, Li R, Mirel DB, Crenshaw A, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Zakai NA, Yango Q, Garcia M, Liu Y, Lumley T, Folsom AR, Reiner AP, Felix JF, Dehghan A, Wilson JG, Bis JC, Fox CS, Glazer NL, Cupples LA, Coresh J, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ, Ganesh SK, null null, Larson EB, Carlson CS, Jarvik GP, null null.
Hum Mol Genet. 2013 May 15;22(10):2119-27.
[Text Abstract on PubMed]

Visceral and Subcutaneous Fat Quality and Cardiometabolic Risk.
Rosenquist KJ, Pedley A, Massaro JM, Therkelsen KE, Murabito JM, Hoffmann U, Fox CS.
JACC Cardiovasc Imaging. 2013 May 6.
[Text Abstract on PubMed]

Editor's note.
Fox CS, Loscalzo J.
Circulation. 2013 Apr 2;127(13):1353.
[Text Abstract on PubMed]

Association of smoking cessation and weight change with cardiovascular disease among adults with and without diabetes.
Clair C, Rigotti NA, Porneala B, Fox CS, D'Agostino RB, Pencina MJ, Meigs JB.
JAMA. 2013 Mar 13;309(10):1014-21.
[Text Abstract on PubMed]

Low Ankle-Brachial Index and the Development of Rapid Estimated GFR Decline and CKD.
Foster MC, Ghuman N, Hwang SJ, Murabito JM, Fox CS.
Am. J. Kidney Dis. 2013 Feb;61(2):204-10.
[Text Abstract on PubMed]

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M, LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stum.
Nat. Genet. 2013 Feb;45(2):145-54.
[Text Abstract on PubMed]

SNP prioritization using a bayesian probability of association.
Thompson JR, Gögele M, Weichenberger CX, Modenese M, Attia J, Barrett JH, Boehnke M, De Grandi A, Domingues FS, Hicks AA, Marroni F, Pattaro C, Ruggeri F, Borsani G, Casari G, Parmigiani G, Pastore A, Pfeufer A, Schwienbacher C, Taliun D, Consortium C, Fox CS, Pramstaller PP, Minelli C.
Genet. Epidemiol. 2013 Feb;37(2):214-21.
[Text Abstract on PubMed]

Importance of different types of prior knowledge in selecting genome-wide findings for follow-up.
Minelli C, De Grandi A, Weichenberger CX, Gögele M, Modenese M, Attia J, Barrett JH, Boehnke M, Borsani G, Casari G, Fox CS, Freina T, Hicks AA, Marroni F, Parmigiani G, Pastore A, Pattaro C, Pfeufer A, Ruggeri F, Schwienbacher C, Taliun D, Pramstaller PP, Domingues FS, Thompson JR.
Genet. Epidemiol. 2013 Feb;37(2):205-13.
[Text Abstract on PubMed]

Intramuscular Fat and Associations With Metabolic Risk Factors in the Framingham Heart Study.
Therkelsen KE, Pedley A, Speliotes EK, Massaro JM, Murabito J, Hoffmann U, Fox CS.
Arterioscler. Thromb. Vasc. Biol. 2013 Jan 24.
[Text Abstract on PubMed]

Early-Adulthood Cardiovascular Disease Risk Factor Profiles Among Individuals With and Without Diabetes in the Framingham Heart Study.
Preis SR, Pencina MJ, Mann DM, D'Agostino, Savage PJ, Fox CS.
Diabetes Care. 2013 Jan 22.
[Text Abstract on PubMed]

Association of chronic kidney disease with adverse outcomes - Authors' reply.
Mahmoodi BK, Fox CS, Astor BC, Nelson RG, Matsushita K, Coresh J, null null.
Lancet. 2013 Feb 16;381(9866):532-3.
[Text Abstract on PubMed]

Relation of circulating liver transaminase concentrations to risk of new-onset atrial fibrillation.
Sinner MF, Wang N, Fox CS, Fontes JD, Rienstra M, Magnani JW, Vasan RS, Calderwood AH, Pencina M, Sullivan LM, Ellinor PT, Benjamin EJ.
Am. J. Cardiol. 2013 Jan 15;111(2):219-24.
[Text Abstract on PubMed]

Differential associations of abdominal visceral, subcutaneous adipose tissue with cardiometabolic risk factors between african and european americans.
Liu J, Coady S, Carr JJ, Md UH, Taylor HA, Fox CS.
Obesity (Silver Spring). 2013 Feb 14.
[Text Abstract on PubMed]

Resequencing and Clinical Associations of the 9p21.3 Region: A Comprehensive Investigation in the Framingham Heart Study.
Johnson AD, Hwang SJ, Voorman A, Morrison A, Peloso GM, Hu YH, Thanassoulis G, Newton-Cheh C, Rogers IS, Hoffman U, Freedman JE, Fox CS, Psaty BM, Boerwinkle E, Cupples LA, O'Donnell CJ.
Circulation. 2013 Jan 11.
[Text Abstract on PubMed]

Risk of type 2 diabetes and cumulative excess weight exposure in the framingham offspring study.
Bouchard DR, Porneala B, Janssen I, Langlois MF, Baillargeon JP, Fox CS, Meigs JB, D'Agostino, Pencina M, Hivert MF.
J. Diabetes Complicat. 2013 Jan 9.
[Text Abstract on PubMed]

Association of female reproductive factors with body composition: the framingham heart study.
Trikudanathan S, Pedley A, Massaro JM, Hoffmann U, Seely EW, Murabito JM, Fox CS.
J. Clin. Endocrinol. Metab. 2013 Jan;98(1):236-44.
[Text Abstract on PubMed]

Aminotransferase levels are associated with cardiometabolic risk above and beyond visceral fat and insulin resistance: the Framingham Heart Study.
Porter SA, Pedley A, Massaro JM, Vasan RS, Hoffmann U, Fox CS.
Arterioscler. Thromb. Vasc. Biol. 2013 Jan;33(1):139-46.
[Text Abstract on PubMed]

Neck circumference and the development of cardiovascular disease risk factors in the Framingham Heart Study.
Preis SR, Pencina MJ, D'Agostino, Meigs JB, Vasan RS, Fox CS.
Diabetes Care. 2013 Jan;36(1):e3.
[Text Abstract on PubMed]

Yogurt consumption is associated with better diet quality and metabolic profile in American men and women.
Wang H, Livingston KA, Fox CS, Meigs JB, Jacques PF.
Nutr Res. 2013 Jan;33(1):18-26.
[Text Abstract on PubMed]

Multidisciplinary collaborative development of a plain-language prenatal education book.
Mottl-Santiago J, Fox CS, Pecci CC, Iverson R.
J Midwifery Womens Health. 2013 May ;58(3):271-7.
[Text Abstract on PubMed]

Dietary patterns, abdominal visceral adipose tissue, and cardiometabolic risk factors in African Americans: the Jackson heart study.
Liu J, Hickson DA, Musani SK, Talegawkar SA, Carithers TC, Tucker KL, Fox CS, Taylor HA.
Obesity (Silver Spring). 2013 Mar ;21(3):644-51.
[Text Abstract on PubMed]

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu T, Hu YJ, Lee SH, Liang L, Lin DY, Min JL, Neale BM, Thorleifsson G, Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N, Fischer K, Goel A, Hottenga JJ, Huffman JE, Jarick I, Johansson Å, Johnson T, Kanoni S, Kleber ME, König IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C, Li G, Mangino M, McArdle WL, Medina-Gomez C, Müller-Nurasyid M, Ngwa JS, Nolte IM, Paternoster L, Pechlivanis S, Perola M, Peters MJ, Preuss M, Rose LM, Shi J, Shungin D, Smith AV, Strawbridge RJ, Surakka I, Teumer A, Trip MD, Tyrer J, Van Vliet-Ostaptchouk JV, Vandenput L, Waite LL, Zhao JH, Absher D, Asselbergs FW, Atalay M, Attwood AP, Balmforth AJ, Basart H, Beilby J, Bonnycastle LL, Brambilla P, Bruinenberg M, Campbell H, Chasman DI, Chines PS, Collins FS, Connell JM, Cookson WO, de Faire U, de Vegt F, Dei M, Dimitriou M, Edkins S, Estrada K, Evans DM, Farrall M, Ferrario MM, Ferrières J, Franke L, Frau F, Gejman PV, Grallert H, Grönberg H, Gudnason V, Hall AS, Hall P, Hartikainen AL, Hayward C, Heard-Costa NL, Heath AC, Hebebrand J, Homuth G, Hu FB, Hunt SE, Hyppönen E, Iribarren C, Jacobs KB, Jansson JO, Jula A, Kähönen M, Kathiresan S, Kee F, Khaw KT, Kivimäki M, Koenig W, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Laitinen JH, Lakka TA, Langenberg C, Launer LJ, Lind L, Lindström J, Liu J, Liuzzi A, Lokki ML, Lorentzon M, Madden PA, Magnusson PK, Manunta P, Marek D, März W, M.
Nat Genet. 2013 May ;45(5):501-12.
[Text Abstract on PubMed]

Overlap Between Common Genetic Polymorphisms Underpinning Kidney Traits and Cardiovascular Disease Phenotypes: The CKDGen Consortium.
Olden M, Teumer A, Bochud M, Pattaro C, Köttgen A, Turner ST, Rettig R, Chen MH, Dehghan A, Bastardot F, Schmidt R, Vollenweider P, Schunkert H, Reilly MP, Fornage M, Launer LJ, Verwoert GC, Mitchell GF, Bis JC, O'Donnell CJ, Cheng CY, Sim X, Siscovick DS, Coresh J, Kao WH, Fox CS, O'Seaghdha CM, null null.
Am J Kidney Dis. 2013 Jun ;61(6):889-98.
[Text Abstract on PubMed]

Lack of interaction of beta-cell-function-associated variants with hypertension on change in fasting glucose and diabetes risk: the Framingham Offspring Study.
de Miguel-Yanes JM, Porneala B, Pencina MJ, Fox CS, Florez JC, Siscovick DS, Dupuis J, Meigs JB.
J Hypertens. 2013 May ;31(5):1001-9.
[Text Abstract on PubMed]

Exome sequencing and genome-wide linkage analysis in 17 families illustrate the complex contribution of TTN truncating variants to dilated cardiomyopathy.
Norton N, Li D, Rampersaud E, Morales A, Martin ER, Zuchner S, Guo S, Gonzalez M, Hedges DJ, Robertson PD, Krumm N, Nickerson DA, Hershberger RE, null null.
Circ Cardiovasc Genet. 2013 Apr ;6(2):144-53.
[Text Abstract on PubMed]

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.
Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Böhringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gögele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Räikkönen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, Vermeulen SH, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S.
PLoS Genet. 2013 01 ;9(2):e1003266.
[Text Abstract on PubMed]

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.
Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, Viikari J, Lohman KK, Ferrucci L, Melhus H, Ingelsson E, Byberg L, Lind L, Lorentzon M, Salomaa V, Campbell H, Dunlop M, Mitchell BD, Herzig KH, Pouta A, Hartikainen AL, null null, Streeten EA, Theodoratou E, Jula A, Wareham NJ, Ohlsson C, Frayling TM, Kritchevsky SB, Spector TD, Richards JB, Lehtimäki T, Ouwehand WH, Kraft P, Cooper C, März W, Power C, Loos RJ, Wang TJ, Järvelin MR, Whittaker JC, Hingorani AD, Hyppönen E.
PLoS Med. 2013 01 ;10(2):e1001383.
[Text Abstract on PubMed]

Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis.
Nitsch D, Grams M, Sang Y, Black C, Cirillo M, Djurdjev O, Iseki K, Jassal SK, Kimm H, Kronenberg F, Oien CM, Levey AS, Levin A, Woodward M, Hemmelgarn BR, null null.
BMJ. 2013 01 ;346:f324.
[Text Abstract on PubMed]

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
Saxena R, Saleheen D, Been LF, Garavito ML, Braun T, Bjonnes A, Young R, Ho WK, Rasheed A, Frossard P, Sim X, Hassanali N, Radha V, Chidambaram M, Liju S, Rees SD, Ng DP, Wong TY, Yamauchi T, Hara K, Tanaka Y, Hirose H, McCarthy MI, Morris AP, null null, null null, null null, Basit A, Barnett AH, Katulanda P, Matthews D, Mohan V, Wander GS, Singh JR, Mehra NK, Ralhan S, Kamboh MI, Mulvihill JJ, Maegawa H, Tobe K, Maeda S, Cho YS, Tai ES, Kelly MA, Chambers JC, Kooner JS, Kadowaki T, Deloukas P, Rader DJ, Danesh J, Sanghera DK.
Diabetes. 2013 May ;62(5):1746-55.
[Text Abstract on PubMed]

Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.
Tabassum R, Chauhan G, Dwivedi OP, Mahajan A, Jaiswal A, Kaur I, Bandesh K, Singh T, Mathai BJ, Pandey Y, Chidambaram M, Sharma A, Chavali S, Sengupta S, Ramakrishnan L, Venkatesh P, Aggarwal SK, Ghosh S, Prabhakaran D, Srinath RK, Saxena M, Banerjee M, Mathur S, Bhansali A, Shah VN, Madhu SV, Marwaha RK, Basu A, Scaria V, McCarthy MI, null null, null null, Venkatesan R, Mohan V, Tandon N, Bharadwaj D.
Diabetes. 2013 Mar ;62(3):977-86.
[Text Abstract on PubMed]

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G, CARDIoGRAM Consortium, ICBP Consortium, CARe Consortium, WTCCC2, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I.
Hum. Mol. Genet. 2012 Dec 15;21(24):5329-43.
[Text Abstract on PubMed]

Weighty matters: balancing weight gain with cardiovascular risk among patients with type 1 diabetes mellitus on intensive insulin therapy.
Fox CS.
Circulation. 2013 Jan 15;127(2):157-9.
[Text Abstract on PubMed]

Relations of long-term and contemporary lipid levels and lipid genetic risk scores with coronary artery calcium in the framingham heart study.
Tsao CW, Preis SR, Peloso GM, Hwang SJ, Kathiresan S, Fox CS, Cupples LA, Hoffmann U, O'Donnell CJ.
J Am Coll Cardiol. 2012 Dec 11;60(23):2364-71.
[Text Abstract on PubMed]

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants.
Fu W, O'Connor TD, Jun G, Kang HM, Abecasis G, Leal SM, Gabriel S, Rieder MJ, Altshuler D, Shendure J, Nickerson DA, Bamshad MJ, null null, Akey JM.
Nature. 2013 Jan 10;493(7431):216-20.
[Text Abstract on PubMed]

Calcium intake is not associated with increased coronary artery calcification: the Framingham Study.
Samelson EJ, Booth SL, Fox CS, Tucker KL, Wang TJ, Hoffmann U, Cupples LA, O'Donnell CJ, Kiel DP.
Am. J. Clin. Nutr. 2012 Dec;96(6):1274-80.
[Text Abstract on PubMed]

Periaortic adipose tissue and aortic dimensions in the framingham heart study.
Thanassoulis G, Massaro JM, Corsini E, Rogers I, Schlett CL, Meigs JB, Hoffmann U, O'Donnell CJ, Fox CS.
J Am Heart Assoc. 2012 Dec;1(6):e000885.
[Text Abstract on PubMed]

Prevalence, distribution, and risk factor correlates of high thoracic periaortic fat in the framingham heart study.
Britton KA, Pedley A, Massaro JM, Corsini EM, Murabito JM, Hoffmann U, Fox CS.
J Am Heart Assoc. 2012 Dec;1(6):e004200.
[Text Abstract on PubMed]

Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association.
Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Franco S, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Huffman MD, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Magid D, Marcus GM, Marelli A, Matchar DB, McGuire DK, Mohler ER, Moy CS, Mussolino ME, Nichol G, Paynter NP, Schreiner PJ, Sorlie PD, Stein J, Turan TN, Virani SS, Wong ND, Woo D, Turner MB, null null.
Circulation. 2013 Jan 1;127(1):143-52.
[Text Abstract on PubMed]

Heart disease and stroke statistics--2013 update: a report from the American Heart Association.
Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Franco S, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Huffman MD, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Magid D, Marcus GM, Marelli A, Matchar DB, McGuire DK, Mohler ER, Moy CS, Mussolino ME, Nichol G, Paynter NP, Schreiner PJ, Sorlie PD, Stein J, Turan TN, Virani SS, Wong ND, Woo D, Turner MB, null null.
Circulation. 2013 Jan 1;127(1):e6-e245.
[Text Abstract on PubMed]

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis.
Fox CS, Matsushita K, Woodward M, Bilo HJ, Chalmers J, Heerspink HJ, Lee BJ, Perkins RM, Rossing P, Sairenchi T, Tonelli M, Vassalotti JA, Yamagishi K, Coresh J, de Jong PE, Wen CP, Nelson RG, Chronic Kidney Disease Prognosis Consortium.
Lancet. 2012 Nov 10;380(9854):1662-73.
[Text Abstract on PubMed]

FTO genotype is associated with phenotypic variability of body mass index.
Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong LM, Monda KL, Hadley D, Mahajan A, Li G, Kapur K, Vitart V, Huffman JE, Wang SR, Palmer C, Esko T, Fischer K, Zhao JH, Demirkan A, Isaacs A, Feitosa MF, Luan J, Heard-Costa NL, White C, Jackson AU, Preuss M, Ziegler A, Eriksson J, Kutalik Z, Frau F, Nolte IM, Van Vliet-Ostaptchouk JV, Hottenga JJ, Jacobs KB, Verweij N, Goel A, Medina-Gomez C, Estrada K, Bragg-Gresham JL, Sanna S, Sidore C, Tyrer J, Teumer A, Prokopenko I, Mangino M, Lindgren CM, Assimes TL, Shuldiner AR, Hui J, Beilby JP, McArdle WL, Hall P, Haritunians T, Zgaga L, Kolcic I, Polasek O, Zemunik T, Oostra BA, Junttila MJ, Grönberg H, Schreiber S, Peters A, Hicks AA, Stephens J, Foad NS, Laitinen J, Pouta A, Kaakinen M, Willemsen G, Vink JM, Wild SH, Navis G, Asselbergs FW, Homuth G, John U, Iribarren C, Harris T, Launer L, Gudnason V, O'Connell JR, Boerwinkle E, Cadby G, Palmer LJ, James AL, Musk AW, Ingelsson E, Psaty BM, Beckmann JS, Waeber G, Vollenweider P, Hayward C, Wright AF, Rudan I, Groop LC, Metspalu A, Khaw KT, van Duijn CM, Borecki IB, Province MA, Wareham NJ, Tardif JC, Huikuri HV, Cupples LA, Atwood LD, Fox CS, Boehnke M, Collins FS, Mohlke KL, Erdmann J, Schunkert H, Hengstenberg C, Stark K, Lorentzon M, Ohlsson C, Cusi D, Staessen JA, Van der Klauw MM, Pramstaller PP, Kathiresan S, Jolley JD, Ripatti S, Jarvelin MR, de Geus EJ, Boomsma DI, Penninx B, Wilson JF, Campbell H, Chanock SJ, van der Harst P, Hamsten A, Watkins H, Hofman A, Witteman JC, Zillikens MC, Uitterlinden AG, Rivadeneira F, Zillikens MC, Kiemeney LA, Vermeulen SH, Abecasi.
Nature. 2012 Oct 11;490(7419):267-72.
[Text Abstract on PubMed]

Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F, Glazer NL, Kapur K, Kema IP, Lopez LM, Schillert A, Smith AV, Winkler CA, Zgaga L, LifeLines Cohort Study, Bandinelli S, Bergmann S, Boban M, Bochud M, Chen YD, Davies G, Dehghan A, Ding J, Doering A, Durda JP, Ferrucci L, Franco OH, Franke L, Gunjaca G, Hofman A, Hsu FC, Kolcic I, Kraja A, Kubo M, Lackner KJ, Launer L, Loehr LR, Li G, Meisinger C, Nakamura Y, Schwienbacher C, Starr JM, Takahashi A, Torlak V, Uitterlinden AG, Vitart V, Waldenberger M, Wild PS, Kirin M, Zeller T, Zemunik T, Zhang Q, Ziegler A, Blankenberg S, Boerwinkle E, Borecki IB, Campbell H, Deary IJ, Frayling TM, Gieger C, Harris TB, Hicks AA, Koenig W, O' Donnell CJ, Fox CS, Pramstaller PP, Psaty BM, Reiner AP, Rotter JI, Rudan I, Snieder H, Tanaka T, van Duijn CM, Vollenweider P, Waeber G, Wilson JF, Witteman JC, Wolffenbuttel BH, Wright AF, Wu Q, Liu Y, Jenny NS, North KE, Felix JF, Alizadeh BZ, Cupples LA, Perry JR, Morris AP.
Am. J. Hum. Genet. 2012 Oct 5;91(4):744-53.
[Text Abstract on PubMed]

Depressive symptoms are associated with visceral adiposity in a community-based sample of middle-aged women and men.
Murabito JM, Massaro JM, Clifford B, Hoffmann U, Fox CS.
Obesity (Silver Spring). 2012 Nov 5.
[Text Abstract on PubMed]

The ratio of visceral to subcutaneous fat, a metric of body fat distribution, is a unique correlate of cardiometabolic risk.
Kaess BM, Pedley A, Massaro JM, Murabito J, Hoffmann U, Fox CS.
Diabetologia. 2012 Oct;55(10):2622-30.
[Text Abstract on PubMed]

Fatty liver, abdominal adipose tissue and atherosclerotic calcification in African Americans: the Jackson Heart Study.
Liu J, Musani SK, Bidulescu A, Carr JJ, Wilson JG, Taylor HA, Fox CS.
Atherosclerosis. 2012 Oct;224(2):521-5.
[Text Abstract on PubMed]

Prevalence and distribution of abdominal aortic calcium by gender and age group in a community-based cohort (from the Framingham Heart Study).
Chuang ML, Massaro JM, Levitzky YS, Fox CS, Manders ES, Hoffmann U, O'Donnell CJ.
Am. J. Cardiol. 2012 Sep 15;110(6):891-6.
[Text Abstract on PubMed]

Fasting glucose, obesity, and coronary artery calcification in community-based people without diabetes.
Rutter MK, Massaro JM, Hoffmann U, O'Donnell CJ, Fox CS.
Diabetes Care. 2012 Sep;35(9):1944-50.
[Text Abstract on PubMed]

Addition of inflammatory biomarkers did not improve diabetes prediction in the community: the framingham heart study.
Dallmeier D, Larson MG, Wang N, Fontes JD, Benjamin EJ, Fox CS.
J Am Heart Assoc. 2012 Aug;1(4):e000869.
[Text Abstract on PubMed]

Validated SNPs for eGFR and their associations with albuminuria.
Ellis JW, Chen MH, Foster MC, Liu CT, Larson MG, de Boer I, Köttgen A, Parsa A, Bochud M, Böger CA, Kao L, Fox CS, O'Seaghdha CM, CKDGen Consortium, CARe Renal Consortium.
Hum. Mol. Genet. 2012 Jul 15;21(14):3293-8.
[Text Abstract on PubMed]

Dietary Patterns, Abdominal Visceral Adipose Tissue and Cardiometabolic Risk Factors in African Americans: the Jackson Heart Study.
Liu J, Hickson DA, Musani SK, Talegawkar SA, Carithers TC, Tucker KL, Fox CS, Taylor HA.
Obesity (Silver Spring). 2012 Jun 12.
[Text Abstract on PubMed]

Metabolite profiling identifies pathways associated with metabolic risk in humans.
Cheng S, Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D, Palma MJ, Roberts LD, Dejam A, Souza AL, Deik AA, Magnusson M, Fox CS, O'Donnell CJ, Vasan RS, Melander O, Clish CB, Gerszten RE, Wang TJ.
Circulation. 2012 May 8;125(18):2222-31.
[Text Abstract on PubMed]

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.
Scott RA, Chu AY, Grarup N, Manning AK, Hivert MF, Shungin D, Tönjes A, Yesupriya A, Barnes D, Bouatia-Naji N, Glazer NL, Jackson AU, Kutalik Z, Lagou V, Marek D, Rasmussen-Torvik LJ, Stringham HM, Tanaka T, Aadahl M, Arking DE, Bergmann S, Boerwinkle E, Bonnycastle LL, Bornstein SR, Brunner E, Bumpstead SJ, Brage S, Carlson OD, Chen H, Chen YD, Chines PS, Collins FS, Couper DJ, Dennison EM, Dowling NF, Egan JS, Ekelund U, Erdos MR, Forouhi NG, Fox CS, Goodarzi MO, Grässler J, Gustafsson S, Hallmans G, Hansen T, Hingorani A, Holloway JW, Hu FB, Isomaa B, Jameson KA, Johansson I, Jonsson A, Jørgensen T, Kivimaki M, Kovacs P, Kumari M, Kuusisto J, Laakso M, Lecoeur C, Lévy-Marchal C, Li G, Loos RJ, Lyssenko V, Marmot M, Marques-Vidal P, Morken MA, Müller G, North KE, Pankow JS, Payne F, Prokopenko I, Psaty BM, Renström F, Rice K, Rotter JI, Rybin D, Sandholt CH, Sayer AA, Shrader P, Schwarz PE, Siscovick DS, Stancáková A, Stumvoll M, Teslovich TM, Waeber G, Williams GH, Witte DR, Wood AR, Xie W, Boehnke M, Cooper C, Ferrucci L, Froguel P, Groop L, Kao WH, Vollenweider P, Walker M, Watanabe RM, Pedersen O, Meigs JB, Ingelsson E, Barroso I, Florez JC, Franks PW, Dupuis J, Wareham NJ, Langenberg C.
Diabetes. 2012 May;61(5):1291-6.
[Text Abstract on PubMed]

Association of pericardial fat and coronary high-risk lesions as determined by cardiac CT.
Schlett CL, Ferencik M, Kriegel MF, Bamberg F, Ghoshhajra BB, Joshi SB, Nagurney JT, Fox CS, Truong QA, Hoffmann U.
Atherosclerosis. 2012 May;222(1):129-34.
[Text Abstract on PubMed]

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, Balasubramanyam A, Barnard J, Bauer F, Baumert J, Bhangale T, Böhm BO, Braund PS, Burton PR, Chandrupatla HR, Clarke R, Cooper-DeHoff RM, Crook ED, Davey-Smith G, Day IN, de Boer A, de Groot MC, Drenos F, Ferguson J, Fox CS, Furlong CE, Gibson Q, Gieger C, Gilhuijs-Pederson LA, Glessner JT, Goel A, Gong Y, Grant SF, Grobbee DE, Hastie C, Humphries SE, Kim CE, Kivimaki M, Kleber M, Meisinger C, Kumari M, Langaee TY, Lawlor DA, Li M, Lobmeyer MT, Maitland-van der Zee AH, Meijs MF, Molony CM, Morrow DA, Murugesan G, Musani SK, Nelson CP, Newhouse SJ, O'Connell JR, Padmanabhan S, Palmen J, Patel SR, Pepine CJ, Pettinger M, Price TS, Rafelt S, Ranchalis J, Rasheed A, Rosenthal E, Ruczinski I, Shah S, Shen H, Silbernagel G, Smith EN, Spijkerman AW, Stanton A, Steffes MW, Thorand B, Trip M, van der Harst P, van der A DL, van Iperen EP, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Wolffenbuttel BH, Young T, Zafarmand MH, Zmuda JM, Look AHEAD Research Group, DIAGRAM consortium, Boehnke M, Altshuler D, McCarthy M, Kao WH, Pankow JS, Cappola TP, Sever P, Poulter N, Caulfield M, Dominiczak A, Shields DC, Bhatt DL, Bhatt D, Zhang L, Curtis SP, Danesh J, Casas JP, van der Schouw YT, Onland-Moret NC, Doevendans PA, Dorn, Farrall M, FitzGerald GA, Hamsten A, Hegele R, Hingorani AD, Hofker MH, Huggins GS, Illig T, Jarvik GP, Johnson JA, Klungel OH, Knowler WC, Koenig W, März W, Meigs JB, Melander O, Munroe PB, Mitchell BD, Bielinski SJ, Rader DJ, Reilly MP, Rich SS, Rotter JI, Saleheen D, Samani NJ, Schadt EE, Shuldi.
Am. J. Hum. Genet. 2012 Mar 9;90(3):410-25.
[Text Abstract on PubMed]

Relation of vascular growth factors with CT-derived measures of body fat distribution: the Framingham Heart Study.
Kaess BM, Pedley A, Massaro JM, Larson MG, Corsini E, Hoffmann U, Smith HM, Sawyer DB, Vasan RS, Fox CS.
J. Clin. Endocrinol. Metab. 2012 Mar;97(3):987-94.
[Text Abstract on PubMed]

A risk score for chronic kidney disease in the general population.
O'Seaghdha CM, Lyass A, Massaro JM, Meigs JB, Coresh J, D'Agostino, Astor BC, Fox CS.
Am. J. Med. 2012 Mar;125(3):270-7.
[Text Abstract on PubMed]

Meta-analysis of genome-wide linkage scans for renal function traits.
Rao M, Mottl AK, Cole SA, Umans JG, Freedman BI, Bowden DW, Langefeld CD, Fox CS, Yang Q, Cupples A, Iyengar SK, Hunt SC, Trikalinos TA.
Nephrol. Dial. Transplant. 2012 Feb;27(2):647-56.
[Text Abstract on PubMed]

Common genetic variants differentially influence the transition from clinically defined states of fasting glucose metabolism.
Walford GA, Green T, Neale B, Isakova T, Rotter JI, Grant SF, Fox CS, Pankow JS, Wilson JG, Meigs JB, Siscovick DS, Bowden DW, Daly MJ, Florez JC.
Diabetologia. 2012 Feb;55(2):331-9.
[Text Abstract on PubMed]

A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study.
Thanassoulis G, Peloso GM, Pencina MJ, Hoffmann U, Fox CS, Cupples LA, Levy D, D'Agostino RB, Hwang SJ, O'Donnell CJ.
Circ Cardiovasc Genet. 2012 Feb 1;5(1):113-21.
[Text Abstract on PubMed]

Short-term outcomes of acute myocardial infarction in patients with acute kidney injury: a report from the national cardiovascular data registry.
Fox CS, Muntner P, Chen AY, Alexander KP, Roe MT, Wiviott SD.
Circulation. 2012 Jan 24;125(3):497-504.
[Text Abstract on PubMed]

Performance of a genetic risk score for CKD stage 3 in the general population.
O'Seaghdha CM, Yang Q, Wu H, Hwang SJ, Fox CS.
Am. J. Kidney Dis. 2012 Jan;59(1):19-24.
[Text Abstract on PubMed]

Insulin resistance and atrial fibrillation (from the Framingham Heart Study).
Fontes JD, Lyass A, Massaro JM, Rienstra M, Dallmeier D, Schnabel RB, Wang TJ, Vasan RS, Lubitz SA, Magnani JW, Levy D, Ellinor PT, Fox CS, Benjamin EJ.
Am. J. Cardiol. 2012 Jan 1;109(1):87-90.
[Text Abstract on PubMed]

Reference values for normal pulmonary artery dimensions by noncontrast cardiac computed tomography: the Framingham Heart Study.
Truong QA, Massaro JM, Rogers IS, Mahabadi AA, Kriegel MF, Fox CS, O'Donnell CJ, Hoffmann U.
Circ Cardiovasc Imaging. 2012 Jan;5(1):147-54.
[Text Abstract on PubMed]

A genome-wide association search for type 2 diabetes genes in African Americans.
Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, DIAGRAM Consortium, MAGIC Investigators, Ferrara A, Lu L, Ziegler JT, Sale MM, Divers J, Shriner D, Adeyemo A, Rotimi CN, Ng MC, Langefeld CD, Freedman BI, Bowden DW, Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL.
PLoS ONE. 2012;7(1):e29202.
[Text Abstract on PubMed]

Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: the framingham heart study.
O'Seaghdha CM, Hwang SJ, Vasan RS, Larson MG, Hoffmann U, Wang TJ, Fox CS.
BMC Endocr Disord. 2012;12:3.
[Text Abstract on PubMed]

Genome-wide association and functional follow-up reveals new loci for kidney function.
Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa M, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson Å, Tönjes A, Dehghan A, Chouraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G, CARDIoGRAM Consortium, ICBP Consortium, CARe Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu FB, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Koenig W, Illig T, Döring A, Wichmann HE, Kolcic I, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Endlich K, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Giulianini F, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Metzger M, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Du.
PLoS Genet. 2012;8(3):e1002584.
[Text Abstract on PubMed]

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Johnson AD, Foster MC, Greenawalt DM, Griffin P, Ding J, Newman AB, Tylavsky F, Miljkovic I, Kritchevsky SB, Launer L, Garcia M, Eiriksdottir G, Carr JJ, Gudnason V, Harris TB, Cupples LA, Borecki IB.
PLoS Genet. 2012;8(5):e1002695.
[Text Abstract on PubMed]

Genome-wide association of pericardial fat identifies a unique locus for ectopic fat.
Fox CS, White CC, Lohman K, Heard-Costa N, Cohen P, Zhang Y, Johnson AD, Emilsson V, Liu CT, Chen YD, Taylor KD, Allison M, Budoff M, CARDIoGRAM Consortium, Rotter JI, Carr JJ, Hoffmann U, Ding J, Cupples LA, Liu Y.
PLoS Genet. 2012;8(5):e1002705.
[Text Abstract on PubMed]

Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing.
Köttgen A, Yang Q, Shimmin LC, Tin A, Schaeffer C, Coresh J, Liu X, Rampoldi L, Hwang SJ, Boerwinkle E, Hixson JE, Kao WH, Fox CS.
PLoS ONE. 2012;7(5):e38311.
[Text Abstract on PubMed]

Phylloquinone and vitamin D status: associations with incident chronic kidney disease in the Framingham Offspring cohort.
O'Seaghdha CM, Hwang SJ, Holden R, Booth SL, Fox CS.
Am. J. Nephrol. 2012;36(1):68-77.
[Text Abstract on PubMed]

Using family-based imputation in genome-wide association studies with large complex pedigrees: the framingham heart study.
Chen MH, Huang J, Chen WM, Larson MG, Fox CS, Vasan RS, Seshadri S, O'Donnell CJ, Yang Q.
PLoS ONE. 2012;7(12):e51589.
[Text Abstract on PubMed]

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.
O'Donnell CJ, Kavousi M, Smith AV, Kardia SL, Feitosa MF, Hwang SJ, Sun YV, Province MA, Aspelund T, Dehghan A, Hoffmann U, Bielak LF, Zhang Q, Eiriksdottir G, van Duijn CM, Fox CS, de Andrade M, Kraja AT, Sigurdsson S, Elias-Smale SE, Murabito JM, Launer LJ, van der Lugt A, Kathiresan S, CARDIoGRAM Consortium, Krestin GP, Herrington DM, Howard TD, Liu Y, Post W, Mitchell BD, O'Connell JR, Shen H, Shuldiner AR, Altshuler D, Elosua R, Salomaa V, Schwartz SM, Siscovick DS, Voight BF, Bis JC, Glazer NL, Psaty BM, Boerwinkle E, Heiss G, Blankenberg S, Zeller T, Wild PS, Schnabel RB, Schillert A, Ziegler A, Münzel TF, White CC, Rotter JI, Nalls M, Oudkerk M, Johnson AD, Newman AB, Uitterlinden AG, Massaro JM, Cunningham J, Harris TB, Hofman A, Peyser PA, Borecki IB, Cupples LA, Gudnason V, Witteman JC.
Circulation. 2011 Dec 20;124(25):2855-64.
[Text Abstract on PubMed]

Influence of pericoronary adipose tissue on local coronary atherosclerosis as assessed by a novel MDCT volumetric method.
Maurovich-Horvat P, Kallianos K, Engel LC, Szymonifka J, Fox CS, Hoffmann U, Truong QA.
Atherosclerosis. 2011 Nov;219(1):151-7.
[Text Abstract on PubMed]

A comparison of strategies for analyzing dichotomous outcomes in genome-wide association studies with general pedigrees.
Chen MH, Liu X, Wei F, Larson MG, Fox CS, Vasan RS, Yang Q.
Genet. Epidemiol. 2011 Nov;35(7):650-7.
[Text Abstract on PubMed]

Central obesity and cardiovascular outcomes in patients with acute coronary syndrome: observations from the MERLIN-TIMI 36 trial.
Kadakia MB, Fox CS, Scirica BM, Murphy SA, Bonaca MP, Morrow DA.
Heart. 2011 Nov;97(21):1782-7.
[Text Abstract on PubMed]

Fatty liver, abdominal visceral fat, and cardiometabolic risk factors: the Jackson Heart Study.
Liu J, Fox CS, Hickson D, Bidulescu A, Carr JJ, Taylor HA.
Arterioscler. Thromb. Vasc. Biol. 2011 Nov;31(11):2715-22.
[Text Abstract on PubMed]

Fatty kidney, hypertension, and chronic kidney disease: the Framingham Heart Study.
Foster MC, Hwang SJ, Porter SA, Massaro JM, Hoffmann U, Fox CS.
Hypertension. 2011 Nov;58(5):784-90.
[Text Abstract on PubMed]

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, Döring A, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hyppönen E, Janssen HL, Johnson T, Kangas AJ, Kema IP, Kühn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K, Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen-Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, Würtz P, Xu C, Yerges-Armstrong LM, Alcohol Genome-wide Association (AlcGen) Consortium, Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study, Genetic Investigation of Anthropometric Traits (GIANT) Consortium, Global Lipids Genetics Consortium, Genetics of Liver Disease (GOLD) Consortium, International Consortium for Blood Pressure (ICBP-GWAS), Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC), Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Pietiläinen KH, Schu.
Nat. Genet. 2011 Nov;43(11):1131-8.
[Text Abstract on PubMed]

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
Tin A, Woodward OM, Kao WH, Liu CT, Lu X, Nalls MA, Shriner D, Semmo M, Akylbekova EL, Wyatt SB, Hwang SJ, Yang Q, Zonderman AB, Adeyemo AA, Palmer C, Meng Y, Reilly M, Shlipak MG, Siscovick D, Evans MK, Rotimi CN, Flessner MF, Köttgen M, Cupples LA, Fox CS, Köttgen A, CARe and CHARGE Consortia.
Hum. Mol. Genet. 2011 Oct 15;20(20):4056-68.
[Text Abstract on PubMed]

Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease.
de Miguel-Yanes JM, Manning AK, Shrader P, McAteer JB, Goel A, Hamsten A, PROCARDIS, Fox CS, Florez JC, Dupuis J, Meigs JB.
Obesity (Silver Spring). 2011 Oct;19(10):2031-7.
[Text Abstract on PubMed]

Relation of visceral adiposity to circulating natriuretic peptides in ambulatory individuals.
Cheng S, Fox CS, Larson MG, Massaro JM, McCabe EL, Khan AM, Levy D, Hoffmann U, O'Donnell CJ, Miller KK, Newton-Cheh C, Coviello AD, Bhasin S, Vasan RS, Wang TJ.
Am. J. Cardiol. 2011 Oct 1;108(7):979-84.
[Text Abstract on PubMed]

Cardiac natriuretic peptides, obesity, and insulin resistance: evidence from two community-based studies.
Khan AM, Cheng S, Magnusson M, Larson MG, Newton-Cheh C, McCabe EL, Coviello AD, Florez JC, Fox CS, Levy D, Robins SJ, Arora P, Bhasin S, Lam CS, Vasan RS, Melander O, Wang TJ.
J. Clin. Endocrinol. Metab. 2011 Oct;96(10):3242-9.
[Text Abstract on PubMed]

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, Kanoni S, Peden JF, Turrini F, Gustafsson S, Zabena C, Almgren P, Barker DJ, Barnes D, Dennison EM, Eriksson JG, Eriksson P, Eury E, Folkersen L, Fox CS, Frayling TM, Goel A, Gu HF, Horikoshi M, Isomaa B, Jackson AU, Jameson KA, Kajantie E, Kerr-Conte J, Kuulasmaa T, Kuusisto J, Loos RJ, Luan J, Makrilakis K, Manning AK, Martínez-Larrad MT, Narisu N, Nastase Mannila M, Ohrvik J, Osmond C, Pascoe L, Payne F, Sayer AA, Sennblad B, Silveira A, Stancáková A, Stirrups K, Swift AJ, Syvänen AC, Tuomi T, van 't Hooft FM, Walker M, Weedon MN, Xie W, Zethelius B, DIAGRAM Consortium, GIANT Consortium, MuTHER Consortium, CARDIoGRAM Consortium, C4D Consortium, Ongen H, Mälarstig A, Hopewell JC, Saleheen D, Chambers J, Parish S, Danesh J, Kooner J, Ostenson CG, Lind L, Cooper CC, Serrano-Ríos M, Ferrannini E, Forsen TJ, Clarke R, Franzosi MG, Seedorf U, Watkins H, Froguel P, Johnson P, Deloukas P, Collins FS, Laakso M, Dermitzakis ET, Boehnke M, McCarthy MI, Wareham NJ, Groop L, Pattou F, Gloyn AL, Dedoussis GV, Lyssenko V, Meigs JB, Barroso I, Watanabe RM, Ingelsson E, Langenberg C, Hamsten A, Florez JC.
Diabetes. 2011 Oct;60(10):2624-34.
[Text Abstract on PubMed]

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.
Bis JC, Kavousi M, Franceschini N, Isaacs A, Abecasis GR, Schminke U, Post WS, Smith AV, Cupples LA, Markus HS, Schmidt R, Huffman JE, Lehtimäki T, Baumert J, Münzel T, Heckbert SR, Dehghan A, North K, Oostra B, Bevan S, Stoegerer EM, Hayward C, Raitakari O, Meisinger C, Schillert A, Sanna S, Völzke H, Cheng YC, Thorsson B, Fox CS, Rice K, Rivadeneira F, Nambi V, Halperin E, Petrovic KE, Peltonen L, Wichmann HE, Schnabel RB, Dörr M, Parsa A, Aspelund T, Demissie S, Kathiresan S, Reilly MP, Taylor K, Uitterlinden A, Couper DJ, Sitzer M, Kähönen M, Illig T, Wild PS, Orru M, Lüdemann J, Shuldiner AR, Eiriksdottir G, White CC, Rotter JI, Hofman A, Seissler J, Zeller T, Usala G, Ernst F, Launer LJ, D'Agostino, O'Leary DH, Ballantyne C, Thiery J, Ziegler A, Lakatta EG, Chilukoti RK, Harris TB, Wolf PA, Psaty BM, Polak JF, Li X, Rathmann W, Uda M, Boerwinkle E, Klopp N, Schmidt H, Wilson JF, Viikari J, Koenig W, Blankenberg S, Newman AB, Witteman J, Heiss G, Duijn Cv, Scuteri A, Homuth G, Mitchell BD, Gudnason V, O'Donnell CJ, CARDIoGRAM Consortium.
Nat. Genet. 2011 Oct;43(10):940-7.
[Text Abstract on PubMed]

Serum phosphorus predicts incident chronic kidney disease and end-stage renal disease.
O'Seaghdha CM, Hwang SJ, Muntner P, Melamed ML, Fox CS.
Nephrol. Dial. Transplant. 2011 Sep;26(9):2885-90.
[Text Abstract on PubMed]

Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis.
Kanoni S, Nettleton JA, Hivert MF, Ye Z, van Rooij FJ, Shungin D, Sonestedt E, Ngwa JS, Wojczynski MK, Lemaitre RN, Gustafsson S, Anderson JS, Tanaka T, Hindy G, Saylor G, Renstrom F, Bennett AJ, van Duijn CM, Florez JC, Fox CS, Hofman A, Hoogeveen RC, Houston DK, Hu FB, Jacques PF, Johansson I, Lind L, Liu Y, McKeown N, Ordovas J, Pankow JS, Sijbrands EJ, Syvänen AC, Uitterlinden AG, Yannakoulia M, Zillikens MC, MAGIC Investigators, Wareham NJ, Prokopenko I, Bandinelli S, Forouhi NG, Cupples LA, Loos RJ, Hallmans G, Dupuis J, Langenberg C, Ferrucci L, Kritchevsky SB, McCarthy MI, Ingelsson E, Borecki IB, Witteman JC, Orho-Melander M, Siscovick DS, Meigs JB, Franks PW, Dedoussis GV.
Diabetes. 2011 Sep;60(9):2407-16.
[Text Abstract on PubMed]

Genetic association for renal traits among participants of African ancestry reveals new loci for renal function.
Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, Siscovick D, Akylbekova E, Wyatt S, Astor B, Mychaleckjy J, Li M, Reilly MP, Townsend RR, Adeyemo A, Zonderman AB, de Andrade M, Turner ST, Mosley TH, Harris TB, CKDGen Consortium, Rotimi CN, Liu Y, Kardia SL, Evans MK, Shlipak MG, Kramer H, Flessner MF, Dreisbach AW, Goessling W, Cupples LA, Kao WL, Fox CS.
PLoS Genet. 2011 Sep;7(9):e1002264.
[Text Abstract on PubMed]

Characteristics and in-hospital outcomes of patients with non-ST-segment elevation myocardial infarction and chronic kidney disease undergoing percutaneous coronary intervention.
Hanna EB, Chen AY, Roe MT, Wiviott SD, Fox CS, Saucedo JF.
JACC Cardiovasc Interv. 2011 Sep;4(9):1002-8.
[Text Abstract on PubMed]

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.
Böger CA, Gorski M, Li M, Hoffmann MM, Huang C, Yang Q, Teumer A, Krane V, O'Seaghdha CM, Kutalik Z, Wichmann HE, Haak T, Boes E, Coassin S, Coresh J, Kollerits B, Haun M, Paulweber B, Köttgen A, Li G, Shlipak MG, Powe N, Hwang SJ, Dehghan A, Rivadeneira F, Uitterlinden A, Hofman A, Beckmann JS, Krämer BK, Witteman J, Bochud M, Siscovick D, Rettig R, Kronenberg F, Wanner C, Thadhani RI, Heid IM, Fox CS, Kao WH, CKDGen Consortium.
PLoS Genet. 2011 Sep;7(9):e1002292.
[Text Abstract on PubMed]

Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies.
Vassy JL, Shrader P, Jonsson A, Fox CS, Lyssenko V, Isomaa B, Groop L, Meigs JB, Franks PW.
Diabetes Res. Clin. Pract. 2011 Aug;93(2):e76-9.
[Text Abstract on PubMed]

Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study.
Tan ZS, Beiser AS, Fox CS, Au R, Himali JJ, Debette S, Decarli C, Vasan RS, Wolf PA, Seshadri S.
Diabetes Care. 2011 Aug;34(8):1766-70.
[Text Abstract on PubMed]

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
Kilpeläinen TO, Zillikens MC, Stancákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, Vedantam S, Shin SY, Haritunians T, Fu M, Feitosa MF, Kumari M, Halldorsson BV, Tikkanen E, Mangino M, Hayward C, Song C, Arnold AM, Aulchenko YS, Oostra BA, Campbell H, Cupples LA, Davis KE, Döring A, Eiriksdottir G, Estrada K, Fernández-Real JM, Garcia M, Gieger C, Glazer NL, Guiducci C, Hofman A, Humphries SE, Isomaa B, Jacobs LC, Jula A, Karasik D, Karlsson MK, Khaw KT, Kim LJ, Kivimäki M, Klopp N, Kühnel B, Kuusisto J, Liu Y, Ljunggren O, Lorentzon M, Luben RN, McKnight B, Mellström D, Mitchell BD, Mooser V, Moreno JM, Männistö S, O'Connell JR, Pascoe L, Peltonen L, Peral B, Perola M, Psaty BM, Salomaa V, Savage DB, Semple RK, Skaric-Juric T, Sigurdsson G, Song KS, Spector TD, Syvänen AC, Talmud PJ, Thorleifsson G, Thorsteinsdottir U, Uitterlinden AG, van Duijn CM, Vidal-Puig A, Wild SH, Wright AF, Clegg DJ, Schadt E, Wilson JF, Rudan I, Ripatti S, Borecki IB, Shuldiner AR, Ingelsson E, Jansson JO, Kaplan RC, Gudnason V, Harris TB, Groop L, Kiel DP, Rivadeneira F, Walker M, Barroso I, Vollenweider P, Waeber G, Chambers JC, Kooner JS, Soranzo N, Hirschhorn JN, Stefansson K, Wichmann HE, Ohlsson C, O'Rahilly S, Wareham NJ, Speliotes EK, Fox CS, Laakso M, Loos RJ.
Nat. Genet. 2011 Aug;43(8):753-60.
[Text Abstract on PubMed]

The MYH9/APOL1 region and chronic kidney disease in European-Americans.
O'Seaghdha CM, Parekh RS, Hwang SJ, Li M, Köttgen A, Coresh J, Yang Q, Fox CS, Kao WH.
Hum. Mol. Genet. 2011 Jun 15;20(12):2450-6.
[Text Abstract on PubMed]

Association of subcutaneous and visceral adiposity with albuminuria: the Framingham Heart Study.
Foster MC, Hwang SJ, Massaro JM, Hoffmann U, DeBoer IH, Robins SJ, Vasan RS, Fox CS.
Obesity (Silver Spring). 2011 Jun;19(6):1284-9.
[Text Abstract on PubMed]

Lower urinary connective tissue growth factor levels and incident CKD stage 3 in the general population.
O'Seaghdha CM, Hwang SJ, Bhavsar NA, Köttgen A, Coresh J, Astor BC, Fox CS.
Am. J. Kidney Dis. 2011 Jun;57(6):841-9.
[Text Abstract on PubMed]

Multiple loci are associated with white blood cell phenotypes.
Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, Folsom AR, Reiner AP, Gieger C, Lagou V, Felix JF, Völzke H, Gouskova NA, Biffi A, Döring A, Völker U, Chong S, Wiggins KL, Rendon A, Dehghan A, Moore M, Taylor K, Wilson JG, Lettre G, Hofman A, Bis JC, Pirastu N, Fox CS, Meisinger C, Sambrook J, Arepalli S, Nauck M, Prokisch H, Stephens J, Glazer NL, Cupples LA, Okada Y, Takahashi A, Kamatani Y, Matsuda K, Tsunoda T, Tanaka T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N, Stumvoll M, Tönjes A, Prokopenko I, Illig T, Patel KV, Garner SF, Kuhnel B, Mangino M, Oostra BA, Thein SL, Coresh J, Wichmann HE, Menzel S, Lin J, Pistis G, Uitterlinden AG, Spector TD, Teumer A, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Ouwehand WH, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Soranzo N, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ, Ganesh SK.
PLoS Genet. 2011 Jun;7(6):e1002113.
[Text Abstract on PubMed]

Insulin resistance influences the association of adiponectin levels with diabetes incidence in two population-based cohorts: the Cooperative Health Research in the Region of Augsburg (KORA) S4/F4 study and the Framingham Offspring Study.
Hivert MF, Sullivan LM, Shrader P, Fox CS, Nathan DM, D'Agostino, Wilson PW, Kowall B, Herder C, Meisinger C, Thorand B, Rathmann W, Meigs JB.
Diabetologia. 2011 May;54(5):1019-24.
[Text Abstract on PubMed]

Type 2 diabetes risk in persons with dysglycemia: the Framingham Offspring Study.
Wilson PW, D'Agostino RB, Fox CS, Sullivan LM, Meigs JB.
Diabetes Res. Clin. Pract. 2011 Apr;92(1):124-7.
[Text Abstract on PubMed]

Blood pressure and the risk of developing diabetes in african americans and whites: ARIC, CARDIA, and the framingham heart study.
Wei GS, Coady SA, Goff, Brancati FL, Levy D, Selvin E, Vasan RS, Fox CS.
Diabetes Care. 2011 Apr;34(4):873-9.
[Text Abstract on PubMed]

Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans.
Rhee EP, Cheng S, Larson MG, Walford GA, Lewis GD, McCabe E, Yang E, Farrell L, Fox CS, O'Donnell CJ, Carr SA, Vasan RS, Florez JC, Clish CB, Wang TJ, Gerszten RE.
J. Clin. Invest. 2011 Apr;121(4):1402-11.
[Text Abstract on PubMed]

Metabolite profiles and the risk of developing diabetes.
Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A, Melander O, Clish CB, Gerszten RE.
Nat. Med. 2011 Apr;17(4):448-53.
[Text Abstract on PubMed]

No association between hemoglobin A1c and in-hospital mortality in patients with diabetes and acute myocardial infarction.
Britton KA, Aggarwal V, Chen AY, Alexander KP, Amsterdam E, Fraulo E, Muntner P, Thomas L, McGuire DK, Wiviott SD, Roe MT, Schubart UK, Fox CS.
Am. Heart J. 2011 Apr;161(4):657-663.e1.
[Text Abstract on PubMed]

Subclinical and clinical correlates of left ventricular wall motion abnormalities in the community.
Tsao CW, Gona P, Salton C, Danias PG, Blease S, Hoffmann U, Fox CS, Albert M, Levy D, O'Donnell CJ, Manning WJ, Yeon SB.
Am. J. Cardiol. 2011 Mar 15;107(6):949-55.
[Text Abstract on PubMed]

Inflammation, kidney function and albuminuria in the Framingham Offspring cohort.
Upadhyay A, Larson MG, Guo CY, Vasan RS, Lipinska I, O'Donnell CJ, Kathiresan S, Meigs JB, Keaney, Rong J, Benjamin EJ, Fox CS.
Nephrol. Dial. Transplant. 2011 Mar;26(3):920-6.
[Text Abstract on PubMed]

CUBN is a gene locus for albuminuria.
Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, Li M, O'Connell JR, Tanaka T, Peralta CA, Kutalik Z, Luan J, Zhao JH, Hwang SJ, Akylbekova E, Kramer H, van der Harst P, Smith AV, Lohman K, de Andrade M, Hayward C, Kollerits B, Tönjes A, Aspelund T, Ingelsson E, Eiriksdottir G, Launer LJ, Harris TB, Shuldiner AR, Mitchell BD, Arking DE, Franceschini N, Boerwinkle E, Egan J, Hernandez D, Reilly M, Townsend RR, Lumley T, Siscovick DS, Psaty BM, Kestenbaum B, Haritunians T, Bergmann S, Vollenweider P, Waeber G, Mooser V, Waterworth D, Johnson AD, Florez JC, Meigs JB, Lu X, Turner ST, Atkinson EJ, Leak TS, Aasarød K, Skorpen F, Syvänen AC, Illig T, Baumert J, Koenig W, Krämer BK, Devuyst O, Mychaleckyj JC, Minelli C, Bakker SJ, Kedenko L, Paulweber B, Coassin S, Endlich K, Kroemer HK, Biffar R, Stracke S, Völzke H, Stumvoll M, Mägi R, Campbell H, Vitart V, Hastie ND, Gudnason V, Kardia SL, Liu Y, Polasek O, Curhan G, Kronenberg F, Prokopenko I, Rudan I, Arnlöv J, Hallan S, Navis G, CKDGen Consortium, Parsa A, Ferrucci L, Coresh J, Shlipak MG, Bull SB, Paterson NJ, Wichmann HE, Wareham NJ, Loos RJ, Rotter JI, Pramstaller PP, Cupples LA, Beckmann JS, Yang Q, Heid IM, Rettig R, Dreisbach AW, Bochud M, Fox CS, Kao WH.
J. Am. Soc. Nephrol. 2011 Mar;22(3):555-70.
[Text Abstract on PubMed]

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS, NASH CRN, GIANT Consortium, MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB, GOLD Consortium.
PLoS Genet. 2011 Mar;7(3):e1001324.
[Text Abstract on PubMed]

Life-course socioeconomic position and type 2 diabetes mellitus: The Framingham Offspring Study.
Smith BT, Lynch JW, Fox CS, Harper S, Abrahamowicz M, Almeida ND, Loucks EB.
Am. J. Epidemiol. 2011 Feb 15;173(4):438-47.
[Text Abstract on PubMed]

Pericardial fat and echocardiographic measures of cardiac abnormalities: the Jackson Heart Study.
Liu J, Fox CS, Hickson DA, May WL, Ding J, Carr JJ, Taylor HA.
Diabetes Care. 2011 Feb;34(2):341-6.
[Text Abstract on PubMed]

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.
Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, Burton PR, Carty C, Chandrupatla HR, Chen W, Connell J, Dalgeorgou C, Boer Ad, Drenos F, Elbers CC, Fang JC, Fox CS, Frackelton EC, Fuchs B, Furlong CE, Gibson Q, Gieger C, Goel A, Grobbee DE, Hastie C, Howard PJ, Huang GH, Johnson WC, Li Q, Kleber ME, Klein BE, Klein R, Kooperberg C, Ky B, Lacroix A, Lanken P, Lathrop M, Li M, Marshall V, Melander O, Mentch FD, Meyer NJ, Monda KL, Montpetit A, Murugesan G, Nakayama K, Nondahl D, Onipinla A, Rafelt S, Newhouse SJ, Otieno FG, Patel SR, Putt ME, Rodriguez S, Safa RN, Sawyer DB, Schreiner PJ, Simpson C, Sivapalaratnam S, Srinivasan SR, Suver C, Swergold G, Sweitzer NK, Thomas KA, Thorand B, Timpson NJ, Tischfield S, Tobin M, Tomaszewski M, Tomaszweski M, Verschuren WM, Wallace C, Winkelmann B, Zhang H, Zheng D, Zhang L, Zmuda JM, Clarke R, Balmforth AJ, Danesh J, Day IN, Schork NJ, de Bakker PI, Delles C, Duggan D, Hingorani AD, Hirschhorn JN, Hofker MH, Humphries SE, Kivimaki M, Lawlor DA, Kottke-Marchant K, Mega JL, Mitchell BD, Morrow DA, Palmen J, Redline S, Shields DC, Shuldiner AR, Sleiman PM, Smith GD, Farrall M, Jamshidi Y, Christiani DC, Casas JP, Hall AS, Doevendans PA, Christie JD, Berenson GS, Murray SS, Illig T, Dorn, Cappola TP.
Am. J. Hum. Genet. 2011 Jan 7;88(1):6-18.
[Text Abstract on PubMed]

Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.
de Miguel-Yanes JM, Shrader P, Pencina MJ, Fox CS, Manning AK, Grant RW, Dupuis J, Florez JC, D'Agostino, Cupples LA, Meigs JB, MAGIC Investigators, DIAGRAM+ Investigators.
Diabetes Care. 2011 Jan;34(1):121-5.
[Text Abstract on PubMed]

The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site.
Richardson K, Louie-Gao Q, Arnett DK, Parnell LD, Lai CQ, Davalos A, Fox CS, Demissie S, Cupples LA, Fernandez-Hernando C, Ordovas JM.
PLoS ONE. 2011;6(4):e17944.
[Text Abstract on PubMed]

Trefoil factor 3 predicts incident chronic kidney disease: a case-control study nested within the Atherosclerosis Risk in Communities (ARIC) study.
Astor BC, Köttgen A, Hwang SJ, Bhavsar N, Fox CS, Coresh J.
Am. J. Nephrol. 2011;34(4):291-7.
[Text Abstract on PubMed]

Development and reproducibility of a computed tomography-based measurement of renal sinus fat.
Foster MC, Hwang SJ, Porter SA, Massaro JM, Hoffmann U, Fox CS.
BMC Nephrol. 2011;12:52.
[Text Abstract on PubMed]

Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.
Foster MC, Yang Q, Hwang SJ, Hoffmann U, Fox CS.
BMC Med. Genet. 2011;12:148.
[Text Abstract on PubMed]

Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: the Jackson Heart Study.
Liu J, Fox CS, Hickson DA, May WD, Hairston KG, Carr JJ, Taylor HA.
J. Clin. Endocrinol. Metab. 2010 Dec;95(12):5419-26.
[Text Abstract on PubMed]

Common variants at 10 genomic loci influence hemoglobin A1(C) levels via glycemic and nonglycemic pathways.
Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C, Prokopenko I, Stolerman E, Sandhu MS, Heeney MM, Devaney JM, Reilly MP, Ricketts SL, Stewart AF, Voight BF, Willenborg C, Wright B, Altshuler D, Arking D, Balkau B, Barnes D, Boerwinkle E, Böhm B, Bonnefond A, Bonnycastle LL, Boomsma DI, Bornstein SR, Böttcher Y, Bumpstead S, Burnett-Miller MS, Campbell H, Cao A, Chambers J, Clark R, Collins FS, Coresh J, de Geus EJ, Dei M, Deloukas P, Döring A, Egan JM, Elosua R, Ferrucci L, Forouhi N, Fox CS, Franklin C, Franzosi MG, Gallina S, Goel A, Graessler J, Grallert H, Greinacher A, Hadley D, Hall A, Hamsten A, Hayward C, Heath S, Herder C, Homuth G, Hottenga JJ, Hunter-Merrill R, Illig T, Jackson AU, Jula A, Kleber M, Knouff CW, Kong A, Kooner J, Köttgen A, Kovacs P, Krohn K, Kühnel B, Kuusisto J, Laakso M, Lathrop M, Lecoeur C, Li M, Li M, Loos RJ, Luan J, Lyssenko V, Mägi R, Magnusson PK, Mälarstig A, Mangino M, Martínez-Larrad MT, März W, McArdle WL, McPherson R, Meisinger C, Meitinger T, Melander O, Mohlke KL, Mooser VE, Morken MA, Narisu N, Nathan DM, Nauck M, O'Donnell C, Oexle K, Olla N, Pankow JS, Payne F, Peden JF, Pedersen NL, Peltonen L, Perola M, Polasek O, Porcu E, Rader DJ, Rathmann W, Ripatti S, Rocheleau G, Roden M, Rudan I, Salomaa V, Saxena R, Schlessinger D, Schunkert H, Schwarz P, Seedorf U, Selvin E, Serrano-Ríos M, Shrader P, Silveira A, Siscovick D, Song K, Spector TD, Stefansson K, Steinthorsdottir V, Strachan DP, Strawbridge R, Stumvoll M, Surakka I, Swift AJ, Tanaka T, Teumer A, Thorleifsson G, Thorsteinsdottir U, Tönjes A, Usala G, Vitart V, Völzke H, Wallaschofski H, Waterworth DM, Watkins H, Wichmann HE, Wild .
Diabetes. 2010 Dec;59(12):3229-39.
[Text Abstract on PubMed]

Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.
Yang Q, Köttgen A, Dehghan A, Smith AV, Glazer NL, Chen MH, Chasman DI, Aspelund T, Eiriksdottir G, Harris TB, Launer L, Nalls M, Hernandez D, Arking DE, Boerwinkle E, Grove ML, Li M, Linda Kao WH, Chonchol M, Haritunians T, Li G, Lumley T, Psaty BM, Shlipak M, Hwang SJ, Larson MG, O'Donnell CJ, Upadhyay A, van Duijn CM, Hofman A, Rivadeneira F, Stricker B, Uitterlinden AG, Paré G, Parker AN, Ridker PM, Siscovick DS, Gudnason V, Witteman JC, Fox CS, Coresh J.
Circ Cardiovasc Genet. 2010 Dec;3(6):523-30.
[Text Abstract on PubMed]

A multi-marker approach to predict incident CKD and microalbuminuria.
Fox CS, Gona P, Larson MG, Selhub J, Tofler G, Hwang SJ, Meigs JB, Levy D, Wang TJ, Jacques PF, Benjamin EJ, Vasan RS.
J. Am. Soc. Nephrol. 2010 Dec;21(12):2143-9.
[Text Abstract on PubMed]

Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart study.
Preis SR, Massaro JM, Robins SJ, Hoffmann U, Vasan RS, Irlbeck T, Meigs JB, Sutherland P, D'Agostino, O'Donnell CJ, Fox CS.
Obesity (Silver Spring). 2010 Nov;18(11):2191-8.
[Text Abstract on PubMed]

Predictors of incident albuminuria in the Framingham Offspring cohort.
O'Seaghdha CM, Hwang SJ, Upadhyay A, Meigs JB, Fox CS.
Am. J. Kidney Dis. 2010 Nov;56(5):852-60.
[Text Abstract on PubMed]

Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.
O'Seaghdha CM, Yang Q, Glazer NL, Leak TS, Dehghan A, Smith AV, Kao WH, Lohman K, Hwang SJ, Johnson AD, Hofman A, Uitterlinden AG, Chen YD, GEFOS Consortium, Brown EM, Siscovick DS, Harris TB, Psaty BM, Coresh J, Gudnason V, Witteman JC, Liu YM, Kestenbaum BR, Fox CS, Köttgen A.
Hum. Mol. Genet. 2010 Nov 1;19(21):4296-303.
[Text Abstract on PubMed]

Whole- and refined-grain intakes are differentially associated with abdominal visceral and subcutaneous adiposity in healthy adults: the Framingham Heart Study.
McKeown NM, Troy LM, Jacques PF, Hoffmann U, O'Donnell CJ, Fox CS.
Am. J. Clin. Nutr. 2010 Nov;92(5):1165-71.
[Text Abstract on PubMed]

Low hemoglobin A1c and risk of all-cause mortality among US adults without diabetes.
Carson AP, Fox CS, McGuire DK, Levitan EB, Laclaustra M, Mann DM, Muntner P.
Circ Cardiovasc Qual Outcomes. 2010 Nov;3(6):661-7.
[Text Abstract on PubMed]

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Steinthorsdottir V, Thorleifsson G, Zillikens MC, Speliotes EK, Mägi R, Workalemahu T, White CC, Bouatia-Naji N, Harris TB, Berndt SI, Ingelsson E, Willer CJ, Weedon MN, Luan J, Vedantam S, Esko T, Kilpeläinen TO, Kutalik Z, Li S, Monda KL, Dixon AL, Holmes CC, Kaplan LM, Liang L, Min JL, Moffatt MF, Molony C, Nicholson G, Schadt EE, Zondervan KT, Feitosa MF, Ferreira T, Lango Allen H, Weyant RJ, Wheeler E, Wood AR, MAGIC, Estrada K, Goddard ME, Lettre G, Mangino M, Nyholt DR, Purcell S, Smith AV, Visscher PM, Yang J, McCarroll SA, Nemesh J, Voight BF, Absher D, Amin N, Aspelund T, Coin L, Glazer NL, Hayward C, Heard-Costa NL, Hottenga JJ, Johansson A, Johnson T, Kaakinen M, Kapur K, Ketkar S, Knowles JW, Kraft P, Kraja AT, Lamina C, Leitzmann MF, McKnight B, Morris AP, Ong KK, Perry JR, Peters MJ, Polasek O, Prokopenko I, Rayner NW, Ripatti S, Rivadeneira F, Robertson NR, Sanna S, Sovio U, Surakka I, Teumer A, van Wingerden S, Vitart V, Zhao JH, Cavalcanti-Proença C, Chines PS, Fisher E, Kulzer JR, Lecoeur C, Narisu N, Sandholt C, Scott LJ, Silander K, Stark K, Tammesoo ML, Teslovich TM, Timpson NJ, Watanabe RM, Welch R, Chasman DI, Cooper MN, Jansson JO, Kettunen J, Lawrence RW, Pellikka N, Perola M, Vandenput L, Alavere H, Almgren P, Atwood LD, Bennett AJ, Biffar R, Bonnycastle LL, Bornstein SR, Buchanan TA, Campbell H, Day IN, Dei M, Dörr M, Elliott P, Erdos MR, Eriksson JG, Freimer NB, Fu M, Gaget S, Geus EJ, Gjesing AP, Grallert H, Grässler J, Groves CJ, Guiducci C, Hartikainen AL, Hassanali N, Havulinna AS, Herzig KH, Hicks AA, Hui J, Igl W, Jousilahti P, Jula A, Kajantie E, Kinnunen L, Kolcic I, Koskinen S, Kovac.
Nat. Genet. 2010 Nov;42(11):949-60.
[Text Abstract on PubMed]

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, Heid IM, Steinthorsdottir V, Stringham HM, Weedon MN, Wheeler E, Wood AR, Ferreira T, Weyant RJ, Segrè AV, Estrada K, Liang L, Nemesh J, Park JH, Gustafsson S, Kilpeläinen TO, Yang J, Bouatia-Naji N, Esko T, Feitosa MF, Kutalik Z, Mangino M, Raychaudhuri S, Scherag A, Smith AV, Welch R, Zhao JH, Aben KK, Absher DM, Amin N, Dixon AL, Fisher E, Glazer NL, Goddard ME, Heard-Costa NL, Hoesel V, Hottenga JJ, Johansson A, Johnson T, Ketkar S, Lamina C, Li S, Moffatt MF, Myers RH, Narisu N, Perry JR, Peters MJ, Preuss M, Ripatti S, Rivadeneira F, Sandholt C, Scott LJ, Timpson NJ, Tyrer JP, van Wingerden S, Watanabe RM, White CC, Wiklund F, Barlassina C, Chasman DI, Cooper MN, Jansson JO, Lawrence RW, Pellikka N, Prokopenko I, Shi J, Thiering E, Alavere H, Alibrandi MT, Almgren P, Arnold AM, Aspelund T, Atwood LD, Balkau B, Balmforth AJ, Bennett AJ, Ben-Shlomo Y, Bergman RN, Bergmann S, Biebermann H, Blakemore AI, Boes T, Bonnycastle LL, Bornstein SR, Brown MJ, Buchanan TA, Busonero F, Campbell H, Cappuccio FP, Cavalcanti-Proença C, Chen YD, Chen CM, Chines PS, Clarke R, Coin L, Connell J, Day IN, den Heijer M, Duan J, Ebrahim S, Elliott P, Elosua R, Eiriksdottir G, Erdos MR, Eriksson JG, Facheris MF, Felix SB, Fischer-Posovszky P, Folsom AR, Friedrich N, Freimer NB, Fu M, Gaget S, Gejman PV, Geus EJ, Gieger C, Gjesing AP, Goel A, Goyette P, Grallert H, Grässler J, Greenawalt DM, Groves CJ, Gudnason V, Guiducci C, Hartikainen AL, Hassanali N, Hall AS, Havulinna AS, Hayward C, Heath AC, Hengstenberg C, Hicks.
Nat. Genet. 2010 Nov;42(11):937-48.
[Text Abstract on PubMed]

Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, Mägi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridde.
Nature. 2010 Oct 14;467(7317):832-8.
[Text Abstract on PubMed]

Impact of A1C screening criterion on the diagnosis of pre-diabetes among U.S. adults.
Mann DM, Carson AP, Shimbo D, Fonseca V, Fox CS, Muntner P.
Diabetes Care. 2010 Oct;33(10):2190-5.
[Text Abstract on PubMed]

Association of colony-forming units with coronary artery and abdominal aortic calcification.
Cheng S, Cohen KS, Shaw SY, Larson MG, Hwang SJ, McCabe EL, Martin RP, Klein RJ, Hashmi B, Hoffmann U, Fox CS, Vasan RS, O'Donnell CJ, Wang TJ.
Circulation. 2010 Sep 21;122(12):1176-82.
[Text Abstract on PubMed]

Biomarkers of the osteoprotegerin pathway: clinical correlates, subclinical disease, incident cardiovascular disease, and mortality.
Lieb W, Gona P, Larson MG, Massaro JM, Lipinska I, Keaney, Rong J, Corey D, Hoffmann U, Fox CS, Vasan RS, Benjamin EJ, O'Donnell CJ, Kathiresan S.
Arterioscler. Thromb. Vasc. Biol. 2010 Sep;30(9):1849-54.
[Text Abstract on PubMed]

Prevalence, distribution, and risk factor correlates of high pericardial and intrathoracic fat depots in the Framingham heart study.
Thanassoulis G, Massaro JM, Hoffmann U, Mahabadi AA, Vasan RS, O'Donnell CJ, Fox CS.
Circ Cardiovasc Imaging. 2010 Sep;3(5):559-66.
[Text Abstract on PubMed]

Serum gamma-glutamyl transferase and risk of heart failure in the community.
Dhingra R, Gona P, Wang TJ, Fox CS, D'Agostino, Vasan RS.
Arterioscler. Thromb. Vasc. Biol. 2010 Sep;30(9):1855-60.
[Text Abstract on PubMed]

Periaortic fat deposition is associated with peripheral arterial disease: the Framingham heart study.
Fox CS, Massaro JM, Schlett CL, Lehman SJ, Meigs JB, O'Donnell CJ, Hoffmann U, Murabito JM.
Circ Cardiovasc Imaging. 2010 Sep;3(5):515-9.
[Text Abstract on PubMed]

Pericardial fat is associated with prevalent atrial fibrillation: the Framingham Heart Study.
Thanassoulis G, Massaro JM, O'Donnell CJ, Hoffmann U, Levy D, Ellinor PT, Wang TJ, Schnabel RB, Vasan RS, Fox CS, Benjamin EJ.
Circ Arrhythm Electrophysiol. 2010 Aug;3(4):345-50.
[Text Abstract on PubMed]

Visceral fat is associated with lower brain volume in healthy middle-aged adults.
Debette S, Beiser A, Hoffmann U, Decarli C, O'Donnell CJ, Massaro JM, Au R, Himali JJ, Wolf PA, Fox CS, Seshadri S.
Ann. Neurol. 2010 Aug;68(2):136-44.
[Text Abstract on PubMed]

Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.
Meyer TE, Verwoert GC, Hwang SJ, Glazer NL, Smith AV, van Rooij FJ, Ehret GB, Boerwinkle E, Felix JF, Leak TS, Harris TB, Yang Q, Dehghan A, Aspelund T, Katz R, Homuth G, Kocher T, Rettig R, Ried JS, Gieger C, Prucha H, Pfeufer A, Meitinger T, Coresh J, Hofman A, Sarnak MJ, Chen YD, Uitterlinden AG, Chakravarti A, Psaty BM, van Duijn CM, Kao WH, Witteman JC, Gudnason V, Siscovick DS, Fox CS, Köttgen A, Genetic Factors for Osteoporosis Consortium, Meta Analysis of Glucose and Insulin Related Traits Consortium.
PLoS Genet. 2010 Aug;6(8).
[Text Abstract on PubMed]

Simple area-based measurement for multidetector computed tomography to predict left ventricular size.
Schlett CL, Kwait DC, Mahabadi AA, Bamberg F, O'Donnell CJ, Fox CS, Hoffmann U.
Eur Radiol. 2010 Jul;20(7):1590-6.
[Text Abstract on PubMed]

Pericardial adipose tissue, atherosclerosis, and cardiovascular disease risk factors: the Jackson heart study.
Liu J, Fox CS, Hickson D, Sarpong D, Ekunwe L, May WD, Hundley GW, Carr JJ, Taylor HA.
Diabetes Care. 2010 Jul;33(7):1635-9.
[Text Abstract on PubMed]

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.
Qi L, Cornelis MC, Kraft P, Stanya KJ, Linda Kao WH, Pankow JS, Dupuis J, Florez JC, Fox CS, Paré G, Sun Q, Girman CJ, Laurie CC, Mirel DB, Manolio TA, Chasman DI, Boerwinkle E, Ridker PM, Hunter DJ, Meigs JB, Lee CH, Hu FB, van Dam RM, Meta-Analysis of Glucose and Insulin-related traits Consortium (MAGIC), Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium.
Hum. Mol. Genet. 2010 Jul 1;19(13):2706-15.
[Text Abstract on PubMed]

Diet quality, physical activity, smoking status, and weight fluctuation are associated with weight change in women and men.
Kimokoti RW, Newby PK, Gona P, Zhu L, Jasuja GK, Pencina MJ, McKeon-O'Malley C, Fox CS, D'Agostino RB, Millen BE.
J. Nutr. 2010 Jul;140(7):1287-93.
[Text Abstract on PubMed]

Common genetic variants associate with serum phosphorus concentration.
Kestenbaum B, Glazer NL, Köttgen A, Felix JF, Hwang SJ, Liu Y, Lohman K, Kritchevsky SB, Hausman DB, Petersen AK, Gieger C, Ried JS, Meitinger T, Strom TM, Wichmann HE, Campbell H, Hayward C, Rudan I, de Boer IH, Psaty BM, Rice KM, Chen YD, Li M, Arking DE, Boerwinkle E, Coresh J, Yang Q, Levy D, van Rooij FJ, Dehghan A, Rivadeneira F, Uitterlinden AG, Hofman A, van Duijn CM, Shlipak MG, Kao WH, Witteman JC, Siscovick DS, Fox CS.
J. Am. Soc. Nephrol. 2010 Jul;21(7):1223-32.
[Text Abstract on PubMed]

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bengtsson Boström K, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM,.
Nat. Genet. 2010 Jul;42(7):579-89.
[Text Abstract on PubMed]

Analyze multivariate phenotypes in genetic association studies by combining univariate association tests.
Yang Q, Wu H, Guo CY, Fox CS.
Genet. Epidemiol. 2010 Jul;34(5):444-54.
[Text Abstract on PubMed]

Peri-aortic fat, cardiovascular disease risk factors, and aortic calcification: the Framingham Heart Study.
Lehman SJ, Massaro JM, Schlett CL, O'Donnell CJ, Hoffmann U, Fox CS.
Atherosclerosis. 2010 Jun;210(2):656-61.
[Text Abstract on PubMed]

Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study.
Speliotes EK, Massaro JM, Hoffmann U, Vasan RS, Meigs JB, Sahani DV, Hirschhorn JN, O'Donnell CJ, Fox CS.
Hepatology. 2010 Jun;51(6):1979-87.
[Text Abstract on PubMed]

Pericardial fat volume correlates with inflammatory markers: the Framingham Heart Study.
Tadros TM, Massaro JM, Rosito GA, Hoffmann U, Vasan RS, Larson MG, Keaney, Lipinska I, Meigs JB, Kathiresan S, O'Donnell CJ, Fox CS, Benjamin EJ.
Obesity (Silver Spring). 2010 May;18(5):1039-45.
[Text Abstract on PubMed]

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.
Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, Bergmann A, Berne C, Boehnke M, Bonnycastle LL, Bornstein SR, Buchanan TA, Bumpstead SJ, Böttcher Y, Chines P, Collins FS, Cooper CC, Dennison EM, Erdos MR, Ferrannini E, Fox CS, Graessler J, Hao K, Isomaa B, Jameson KA, Kovacs P, Kuusisto J, Laakso M, Ladenvall C, Mohlke KL, Morken MA, Narisu N, Nathan DM, Pascoe L, Payne F, Petrie JR, Sayer AA, Schwarz PE, Scott LJ, Stringham HM, Stumvoll M, Swift AJ, Syvänen AC, Tuomi T, Tuomilehto J, Tönjes A, Valle TT, Williams GH, Lind L, Barroso I, Quertermous T, Walker M, Wareham NJ, Meigs JB, McCarthy MI, Groop L, Watanabe RM, Florez JC, MAGIC investigators.
Diabetes. 2010 May;59(5):1266-75.
[Text Abstract on PubMed]

Relations of insulin resistance and glycemic abnormalities to cardiovascular magnetic resonance measures of cardiac structure and function: the Framingham Heart Study.
Velagaleti RS, Gona P, Chuang ML, Salton CJ, Fox CS, Blease SJ, Yeon SB, Manning WJ, O'Donnell CJ.
Circ Cardiovasc Imaging. 2010 May;3(3):257-63.
[Text Abstract on PubMed]

New loci associated with kidney function and chronic kidney disease.
Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Li M, Schmidt H, Tanaka T, Isaacs A, Ketkar S, Hwang SJ, Johnson AD, Dehghan A, Teumer A, Paré G, Atkinson EJ, Zeller T, Lohman K, Cornelis MC, Probst-Hensch NM, Kronenberg F, Tönjes A, Hayward C, Aspelund T, Eiriksdottir G, Launer LJ, Harris TB, Rampersaud E, Mitchell BD, Arking DE, Boerwinkle E, Struchalin M, Cavalieri M, Singleton A, Giallauria F, Metter J, de Boer IH, Haritunians T, Lumley T, Siscovick D, Psaty BM, Zillikens MC, Oostra BA, Feitosa M, Province M, de Andrade M, Turner ST, Schillert A, Ziegler A, Wild PS, Schnabel RB, Wilde S, Munzel TF, Leak TS, Illig T, Klopp N, Meisinger C, Wichmann HE, Koenig W, Zgaga L, Zemunik T, Kolcic I, Minelli C, Hu FB, Johansson A, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Schreiber S, Aulchenko YS, Felix JF, Rivadeneira F, Uitterlinden AG, Hofman A, Imboden M, Nitsch D, Brandstätter A, Kollerits B, Kedenko L, Mägi R, Stumvoll M, Kovacs P, Boban M, Campbell S, Endlich K, Völzke H, Kroemer HK, Nauck M, Völker U, Polasek O, Vitart V, Badola S, Parker AN, Ridker PM, Kardia SL, Blankenberg S, Liu Y, Curhan GC, Franke A, Rochat T, Paulweber B, Prokopenko I, Wang W, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Shlipak MG, van Duijn CM, Borecki I, Krämer BK, Rudan I, Gyllensten U, Wilson JF, Witteman JC, Pramstaller PP, Rettig R, Hastie N, Chasman DI, Kao WH, Heid IM, Fox CS.
Nat. Genet. 2010 May;42(5):376-84.
[Text Abstract on PubMed]

Consent for genetic research in the Framingham Heart Study.
Levy D, Splansky GL, Strand NK, Atwood LD, Benjamin EJ, Blease S, Cupples LA, D'Agostino, Fox CS, Kelly-Hayes M, Koski G, Larson MG, Mutalik KM, Oberacker E, O'Donnell CJ, Sutherland P, Valentino M, Vasan RS, Wolf PA, Murabito JM.
Am. J. Med. Genet. A. 2010 May;152A(5):1250-6.
[Text Abstract on PubMed]

The association of tumor necrosis factor alpha receptor 2 and tumor necrosis factor alpha with insulin resistance and the influence of adipose tissue biomarkers in humans.
Hivert MF, Sullivan LM, Shrader P, Fox CS, Nathan DM, D'Agostino, Wilson PW, Benjamin EJ, Meigs JB.
Metab. Clin. Exp. 2010 Apr;59(4):540-6.
[Text Abstract on PubMed]

Association between single-slice measurements of visceral and abdominal subcutaneous adipose tissue with volumetric measurements: the Framingham Heart Study.
Irlbeck T, Massaro JM, Bamberg F, O'Donnell CJ, Hoffmann U, Fox CS.
Int J Obes (Lond). 2010 Apr;34(4):781-7.
[Text Abstract on PubMed]

Uromodulin levels associate with a common UMOD variant and risk for incident CKD.
Köttgen A, Hwang SJ, Larson MG, Van Eyk JE, Fu Q, Benjamin EJ, Dehghan A, Glazer NL, Kao WH, Harris TB, Gudnason V, Shlipak MG, Yang Q, Coresh J, Levy D, Fox CS.
J. Am. Soc. Nephrol. 2010 Feb;21(2):337-44.
[Text Abstract on PubMed]

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, Stringham HM, Prokopenko I, Johnson T, Grarup N, Boesgaard TW, Lecoeur C, Shrader P, O'Connell J, Ingelsson E, Couper DJ, Rice K, Song K, Andreasen CH, Dina C, Köttgen A, Le Bacquer O, Pattou F, Taneera J, Steinthorsdottir V, Rybin D, Ardlie K, Sampson M, Qi L, van Hoek M, Weedon MN, Aulchenko YS, Voight BF, Grallert H, Balkau B, Bergman RN, Bielinski SJ, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Buchanan TA, Bumpstead SJ, Cavalcanti-Proença C, Charpentier G, Chen YD, Chines PS, Collins FS, Cornelis M, J Crawford G, Delplanque J, Doney A, Egan JM, Erdos MR, Firmann M, Forouhi NG, Fox CS, Goodarzi MO, Graessler J, Hingorani A, Isomaa B, Jørgensen T, Kivimaki M, Kovacs P, Krohn K, Kumari M, Lauritzen T, Lévy-Marchal C, Mayor V, McAteer JB, Meyre D, Mitchell BD, Mohlke KL, Morken MA, Narisu N, Palmer CN, Pakyz R, Pascoe L, Payne F, Pearson D, Rathmann W, Sandbaek A, Sayer AA, Scott LJ, Sharp SJ, Sijbrands E, Singleton A, Siscovick DS, Smith NL, Sparsø T, Swift AJ, Syddall H, Thorleifsson G, Tönjes A, Tuomi T, Tuomilehto J, Valle TT, Waeber G, Walley A, Waterworth DM, Zeggini E, Zhao JH, GIANT consortium, MAGIC investigators, Illig T, Wichmann HE, Wilson JF, van Duijn C, Hu FB, Morris AD, Frayling TM, Hattersley AT, Thorsteinsdottir U, Stefansson K, Nilsson P, Syvänen AC, Shuldiner AR, Walker M, Bornstein SR, Schwarz P, Williams GH, Nathan DM, Kuusisto J, Laakso M, Cooper C, Marmot M, Ferrucci L, Mooser V, Stumvoll M, Loos RJ, Altshuler D, Psaty BM, Rotter JI, Boerwinkle E, Hansen T, .
Nat. Genet. 2010 Feb;42(2):142-8.
[Text Abstract on PubMed]

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, Perry JR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day IN, de Geus EJ, Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han X, Hartikainen AL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hillman DR, Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PR, Jørgensen T, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McCulloch LJ, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S, Naitza S, Narisu N,.
Nat. Genet. 2010 Feb;42(2):105-16.
[Text Abstract on PubMed]

Use of evidence-based therapies in short-term outcomes of ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction in patients with chronic kidney disease: a report from the National Cardiovascular Data Acute Coronary Treatment and Intervention Outcomes Network registry.
Fox CS, Muntner P, Chen AY, Alexander KP, Roe MT, Cannon CP, Saucedo JF, Kontos MC, Wiviott SD, Acute Coronary Treatment and Intervention Outcomes Network registry.
Circulation. 2010 Jan 26;121(3):357-65.
[Text Abstract on PubMed]

Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study.
Cheng S, Massaro JM, Fox CS, Larson MG, Keyes MJ, McCabe EL, Robins SJ, O'Donnell CJ, Hoffmann U, Jacques PF, Booth SL, Vasan RS, Wolf M, Wang TJ.
Diabetes. 2010 Jan;59(1):242-8.
[Text Abstract on PubMed]

The relation of C--reactive protein to chronic kidney disease in African Americans: the Jackson Heart Study.
Fox ER, Benjamin EJ, Sarpong DF, Nagarajarao H, Taylor JK, Steffes MW, Salahudeen AK, Flessner MF, Akylbekova EL, Fox CS, Garrison RJ, Taylor.
BMC Nephrol. 2010;11:1.
[Text Abstract on PubMed]

Axial area and anteroposterior diameter as estimates of left atrial size using computed tomography of the chest: comparison with 3-dimensional volume.
Mahabadi AA, Truong QA, Schlett CL, Samy B, O'Donnell CJ, Fox CS, Bamberg F, Hoffmann U.
J Cardiovasc Comput Tomogr. 2010 Jan-Feb;4(1):49-54.
[Text Abstract on PubMed]

A three-stage approach for genome-wide association studies with family data for quantitative traits.
Chen MH, Larson MG, Hsu YH, Peloso GM, Guo CY, Fox CS, Atwood LD, Yang Q.
BMC Genet. 2010;11:40.
[Text Abstract on PubMed]

Visceral and subcutaneous adiposity and brachial artery vasodilator function.
Parikh NI, Keyes MJ, Larson MG, Pou KM, Hamburg NM, Vita JA, O'Donnell CJ, Vasan RS, Mitchell GF, Hoffmann U, Fox CS, Benjamin EJ.
Obesity (Silver Spring). 2009 Nov;17(11):2054-9.
[Text Abstract on PubMed]

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.
Ganesh SK, Zakai NA, van Rooij FJ, Soranzo N, Smith AV, Nalls MA, Chen MH, Kottgen A, Glazer NL, Dehghan A, Kuhnel B, Aspelund T, Yang Q, Tanaka T, Jaffe A, Bis JC, Verwoert GC, Teumer A, Fox CS, Guralnik JM, Ehret GB, Rice K, Felix JF, Rendon A, Eiriksdottir G, Levy D, Patel KV, Boerwinkle E, Rotter JI, Hofman A, Sambrook JG, Hernandez DG, Zheng G, Bandinelli S, Singleton AB, Coresh J, Lumley T, Uitterlinden AG, Vangils JM, Launer LJ, Cupples LA, Oostra BA, Zwaginga JJ, Ouwehand WH, Thein SL, Meisinger C, Deloukas P, Nauck M, Spector TD, Gieger C, Gudnason V, van Duijn CM, Psaty BM, Ferrucci L, Chakravarti A, Greinacher A, O'Donnell CJ, Witteman JC, Furth S, Cushman M, Harris TB, Lin JP.
Nat. Genet. 2009 Nov;41(11):1191-8.
[Text Abstract on PubMed]

Arterial stiffness in mild-to-moderate CKD.
Upadhyay A, Hwang SJ, Mitchell GF, Vasan RS, Vita JA, Stantchev PI, Meigs JB, Larson MG, Levy D, Benjamin EJ, Fox CS.
J. Am. Soc. Nephrol. 2009 Sep;20(9):2044-53.
[Text Abstract on PubMed]

Relation of subcutaneous and visceral adipose tissue to coronary and abdominal aortic calcium (from the Framingham Heart Study).
Fox CS, Hwang SJ, Massaro JM, Lieb K, Vasan RS, O'Donnell CJ, Hoffmann U.
Am. J. Cardiol. 2009 Aug 15;104(4):543-7.
[Text Abstract on PubMed]

Trends in cardiovascular disease risk factors in individuals with and without diabetes mellitus in the Framingham Heart Study.
Preis SR, Pencina MJ, Hwang SJ, D'Agostino, Savage PJ, Levy D, Fox CS.
Circulation. 2009 Jul 21;120(3):212-20.
[Text Abstract on PubMed]

Metabolic abnormalities are present in adults with elevated serum cystatin C.
Muntner P, Vupputuri S, Coresh J, Uribarri J, Fox CS.
Kidney Int. 2009 Jul;76(1):81-8.
[Text Abstract on PubMed]

Breastfeeding in infancy and adult cardiovascular disease risk factors.
Parikh NI, Hwang SJ, Ingelsson E, Benjamin EJ, Fox CS, Vasan RS, Murabito JM.
Am. J. Med. 2009 Jul;122(7):656-63.e1.
[Text Abstract on PubMed]

Eligibility of individuals with subclinical coronary artery calcium and intermediate coronary heart disease risk for reclassification (from the Framingham Heart Study).
Preis SR, Hwang SJ, Fox CS, Massaro JM, Levy D, Hoffmann U, O'Donnell CJ.
Am. J. Cardiol. 2009 Jun 15;103(12):1710-5.
[Text Abstract on PubMed]

Abdominal subcutaneous adipose tissue: a protective fat depot?
Porter SA, Massaro JM, Hoffmann U, Vasan RS, O'Donnel CJ, Fox CS.
Diabetes Care. 2009 Jun;32(6):1068-75.
[Text Abstract on PubMed]

Differential estimation of CKD using creatinine- versus cystatin C-based estimating equations by category of body mass index.
Vupputuri S, Fox CS, Coresh J, Woodward M, Muntner P.
Am. J. Kidney Dis. 2009 Jun;53(6):993-1001.
[Text Abstract on PubMed]

Genome-wide association study of blood pressure and hypertension.
Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FU, Smith AV, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJ, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JC, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM.
Nat. Genet. 2009 Jun;41(6):677-87.
[Text Abstract on PubMed]

Multiple loci associated with indices of renal function and chronic kidney disease.
Köttgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, Yang Q, Gudnason V, Launer LJ, Harris TB, Smith AV, Arking DE, Astor BC, Boerwinkle E, Ehret GB, Ruczinski I, Scharpf RB, Chen YD, de Boer IH, Haritunians T, Lumley T, Sarnak M, Siscovick D, Benjamin EJ, Levy D, Upadhyay A, Aulchenko YS, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, Chasman DI, Paré G, Ridker PM, Kao WH, Witteman JC, Coresh J, Shlipak MG, Fox CS.
Nat. Genet. 2009 Jun;41(6):712-7.
[Text Abstract on PubMed]

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.
Heard-Costa NL, Zillikens MC, Monda KL, Johansson A, Harris TB, Fu M, Haritunians T, Feitosa MF, Aspelund T, Eiriksdottir G, Garcia M, Launer LJ, Smith AV, Mitchell BD, McArdle PF, Shuldiner AR, Bielinski SJ, Boerwinkle E, Brancati F, Demerath EW, Pankow JS, Arnold AM, Chen YD, Glazer NL, McKnight B, Psaty BM, Rotter JI, Amin N, Campbell H, Gyllensten U, Pattaro C, Pramstaller PP, Rudan I, Struchalin M, Vitart V, Gao X, Kraja A, Province MA, Zhang Q, Atwood LD, Dupuis J, Hirschhorn JN, Jaquish CE, O'Donnell CJ, Vasan RS, White CC, Aulchenko YS, Estrada K, Hofman A, Rivadeneira F, Uitterlinden AG, Witteman JC, Oostra BA, Kaplan RC, Gudnason V, O'Connell JR, Borecki IB, van Duijn CM, Cupples LA, Fox CS, North KE.
PLoS Genet. 2009 Jun;5(6):e1000539.
[Text Abstract on PubMed]

Heritability of serum gamma-glutamyltransferase level: genetic analysis from the Framingham Offspring Study.
Lin JP, O'Donnell CJ, Fox CS, Cupples LA.
Liver Int. 2009 May;29(5):776-7.
[Text Abstract on PubMed]

Cross-sectional associations between abdominal and thoracic adipose tissue compartments and adiponectin and resistin in the Framingham Heart Study.
Jain SH, Massaro JM, Hoffmann U, Rosito GA, Vasan RS, Raji A, O'Donnell CJ, Meigs JB, Fox CS.
Diabetes Care. 2009 May;32(5):903-8.
[Text Abstract on PubMed]

Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005.
Preis SR, Hwang SJ, Coady S, Pencina MJ, D'Agostino, Savage PJ, Levy D, Fox CS.
Circulation. 2009 Apr 7;119(13):1728-35.
[Text Abstract on PubMed]

Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study.
Mahabadi AA, Massaro JM, Rosito GA, Levy D, Murabito JM, Wolf PA, O'Donnell CJ, Fox CS, Hoffmann U.
Eur. Heart J. 2009 Apr;30(7):850-6.
[Text Abstract on PubMed]

Variants in the CNR1 and the FAAH genes and adiposity traits in the community.
Lieb W, Manning AK, Florez JC, Dupuis J, Cupples LA, McAteer JB, Vasan RS, Hoffmann U, O'Donnell CJ, Meigs JB, Fox CS.
Obesity (Silver Spring). 2009 Apr;17(4):755-60.
[Text Abstract on PubMed]

TCF7L2 variants are associated with increased proinsulin/insulin ratios but not obesity traits in the Framingham Heart Study.
Stolerman ES, Manning AK, McAteer JB, Fox CS, Dupuis J, Meigs JB, Florez JC.
Diabetologia. 2009 Apr;52(4):614-20.
[Text Abstract on PubMed]

Pericardial fat, intrathoracic fat, and measures of left ventricular structure and function: the Framingham Heart Study.
Fox CS, Gona P, Hoffmann U, Porter SA, Salton CJ, Massaro JM, Levy D, Larson MG, D'Agostino, O'Donnell CJ, Manning WJ.
Circulation. 2009 Mar 31;119(12):1586-91.
[Text Abstract on PubMed]

Long-term trends in myocardial infarction incidence and case fatality in the National Heart, Lung, and Blood Institute's Framingham Heart study.
Parikh NI, Gona P, Larson MG, Fox CS, Benjamin EJ, Murabito JM, O'Donnell CJ, Vasan RS, Levy D.
Circulation. 2009 Mar 10;119(9):1203-10.
[Text Abstract on PubMed]

Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study.
Hivert MF, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC.
Diabetes. 2009 Mar;58(3):750-6.
[Text Abstract on PubMed]

Association of lifestyle factors with abdominal subcutaneous and visceral adiposity: the Framingham Heart Study.
Molenaar EA, Massaro JM, Jacques PF, Pou KM, Ellison RC, Hoffmann U, Pencina K, Shadwick SD, Vasan RS, O'Donnell CJ, Fox CS.
Diabetes Care. 2009 Mar;32(3):505-10.
[Text Abstract on PubMed]

Patterns of abdominal fat distribution: the Framingham Heart Study.
Pou KM, Massaro JM, Hoffmann U, Lieb K, Vasan RS, O'Donnell CJ, Fox CS.
Diabetes Care. 2009 Mar;32(3):481-5.
[Text Abstract on PubMed]

Novel measurements of periaortic adipose tissue in comparison to anthropometric measures of obesity, and abdominal adipose tissue.
Schlett CL, Massaro JM, Lehman SJ, Bamberg F, O'Donnell CJ, Fox CS, Hoffmann U.
Int J Obes (Lond). 2009 Feb;33(2):226-32.
[Text Abstract on PubMed]

Association of parental obesity with concentrations of select systemic biomarkers in nonobese offspring: the Framingham Heart Study.
Lieb W, Pencina MJ, Lanier KJ, Tofler GH, Levy D, Fox CS, Wang TJ, D'Agostino, Vasan RS.
Diabetes. 2009 Jan;58(1):134-7.
[Text Abstract on PubMed]

Variants in MTNR1B influence fasting glucose levels.
Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR.
Nat. Genet. 2009 Jan;41(1):77-81.
[Text Abstract on PubMed]

Age-related associations of hypertension and diabetes mellitus with chronic kidney disease.
Islam TM, Fox CS, Mann D, Muntner P.
BMC Nephrol. 2009;10:17.
[Text Abstract on PubMed]

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.
Dehghan A, Köttgen A, Yang Q, Hwang SJ, Kao WL, Rivadeneira F, Boerwinkle E, Levy D, Hofman A, Astor BC, Benjamin EJ, van Duijn CM, Witteman JC, Coresh J, Fox CS.
Lancet. 2008 Dec 6;372(9654):1953-61.
[Text Abstract on PubMed]

Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study.
Hivert MF, Manning AK, McAteer JB, Florez JC, Dupuis J, Fox CS, O'Donnell CJ, Cupples LA, Meigs JB.
Diabetes. 2008 Dec;57(12):3353-9.
[Text Abstract on PubMed]

Aminotransferase levels and 20-year risk of metabolic syndrome, diabetes, and cardiovascular disease.
Goessling W, Massaro JM, Vasan RS, D'Agostino, Ellison RC, Fox CS.
Gastroenterology. 2008 Dec;135(6):1935-44, 1944.e1.
[Text Abstract on PubMed]

Genotype score in addition to common risk factors for prediction of type 2 diabetes.
Meigs JB, Shrader P, Sullivan LM, McAteer JB, Fox CS, Dupuis J, Manning AK, Florez JC, Wilson PW, D'Agostino, Cupples LA.
N. Engl. J. Med. 2008 Nov 20;359(21):2208-19.
[Text Abstract on PubMed]

Relations of measures of endothelial function and kidney disease: the Framingham Heart Study.
Foster MC, Keyes MJ, Larson MG, Vita JA, Mitchell GF, Meigs JB, Vasan RS, Benjamin EJ, Fox CS.
Am. J. Kidney Dis. 2008 Nov;52(5):859-67.
[Text Abstract on PubMed]

Association of visceral and subcutaneous adiposity with kidney function.
Young JA, Hwang SJ, Sarnak MJ, Hoffmann U, Massaro JM, Levy D, Benjamin EJ, Larson MG, Vasan RS, O'Donnell CJ, Fox CS.
Clin J Am Soc Nephrol. 2008 Nov;3(6):1786-91.
[Text Abstract on PubMed]

Defining normal distributions of coronary artery calcium in women and men (from the Framingham Heart Study).
Hoffmann U, Massaro JM, Fox CS, Manders E, O'Donnell CJ.
Am. J. Cardiol. 2008 Nov 1;102(9):1136-41, 1141.e1.
[Text Abstract on PubMed]

Clinical correlates and heritability of cystatin C (from the Framingham Offspring Study).
Parikh NI, Hwang SJ, Yang Q, Larson MG, Guo CY, Robins SJ, Sutherland P, Benjamin EJ, Levy D, Fox CS.
Am. J. Cardiol. 2008 Nov 1;102(9):1194-8.
[Text Abstract on PubMed]

Effect of aging on A1C levels in individuals without diabetes: evidence from the Framingham Offspring Study and the National Health and Nutrition Examination Survey 2001-2004.
Pani LN, Korenda L, Meigs JB, Driver C, Chamany S, Fox CS, Sullivan L, D'Agostino RB, Nathan DM.
Diabetes Care. 2008 Oct;31(10):1991-6.
[Text Abstract on PubMed]

TCF7L2 variants associate with CKD progression and renal function in population-based cohorts.
Köttgen A, Hwang SJ, Rampersaud E, Coresh J, North KE, Pankow JS, Meigs JB, Florez JC, Parsa A, Levy D, Boerwinkle E, Shuldiner AR, Fox CS, Kao WH.
J. Am. Soc. Nephrol. 2008 Oct;19(10):1989-99.
[Text Abstract on PubMed]

Volumetric measurement of pericardial adipose tissue from contrast-enhanced coronary computed tomography angiography: a reproducibility study.
Nichols JH, Samy B, Nasir K, Fox CS, Schulze PC, Bamberg F, Hoffmann U.
J Cardiovasc Comput Tomogr. 2008 Sep-Oct;2(5):288-95.
[Text Abstract on PubMed]

Indexes of kidney function and coronary artery and abdominal aortic calcium (from the Framingham Offspring Study).
Parikh NI, Hwang SJ, Larson MG, Hoffmann U, Levy D, Meigs JB, O'Donnell CJ, Fox CS.
Am. J. Cardiol. 2008 Aug 15;102(4):440-3.
[Text Abstract on PubMed]

Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart study.
Fox CS, Pencina MJ, Wilson PW, Paynter NP, Vasan RS, D'Agostino.
Diabetes Care. 2008 Aug;31(8):1582-4.
[Text Abstract on PubMed]

Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistance.
Hivert MF, Sullivan LM, Fox CS, Nathan DM, D'Agostino, Wilson PW, Meigs JB.
J. Clin. Endocrinol. Metab. 2008 Aug;93(8):3165-72.
[Text Abstract on PubMed]

Burden and rates of treatment and control of cardiovascular disease risk factors in obesity: the Framingham Heart Study.
Molenaar EA, Hwang SJ, Vasan RS, Grobbee DE, Meigs JB, D'Agostino, Levy D, Fox CS.
Diabetes Care. 2008 Jul;31(7):1367-72.
[Text Abstract on PubMed]

Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study.
Stolerman ES, Manning AK, McAteer JB, Dupuis J, Fox CS, Cupples LA, Meigs JB, Florez JC.
Diabetes. 2008 Jul;57(7):1971-7.
[Text Abstract on PubMed]

Trends in diabetes, high cholesterol, and hypertension in chronic kidney disease among U.S. adults: 1988-1994 to 1999-2004.
Fox CS, Muntner P.
Diabetes Care. 2008 Jul;31(7):1337-42.
[Text Abstract on PubMed]

Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study.
Foster MC, Hwang SJ, Larson MG, Lichtman JH, Parikh NI, Vasan RS, Levy D, Fox CS.
Am. J. Kidney Dis. 2008 Jul;52(1):39-48.
[Text Abstract on PubMed]

Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels.
Peter I, Kelley-Hedgepeth A, Fox CS, Cupples LA, Huggins GS, Housman DE, Karas RH, Mendelsohn ME, Levy D, Murabito JM.
J. Clin. Endocrinol. Metab. 2008 Jul;93(7):2779-85.
[Text Abstract on PubMed]

Chronic kidney disease as a predictor of cardiovascular disease (from the Framingham Heart Study).
Parikh NI, Hwang SJ, Larson MG, Levy D, Fox CS.
Am. J. Cardiol. 2008 Jul 1;102(1):47-53.
[Text Abstract on PubMed]

Liver fat is reproducibly measured using computed tomography in the Framingham Heart Study.
Speliotes EK, Massaro JM, Hoffmann U, Foster MC, Sahani DV, Hirschhorn JN, O'Donnell CJ, Fox CS.
J. Gastroenterol. Hepatol. 2008 Jun;23(6):894-9.
[Text Abstract on PubMed]

Lack of association between the type 2 deiodinase A/G polymorphism and hypertensive traits: the Framingham Heart Study.
Maia AL, Hwang SJ, Levy D, Larson MG, Larsen PR, Fox CS.
Hypertension. 2008 Apr;51(4):e22-3.
[Text Abstract on PubMed]

Overweight, obesity, and elevated serum cystatin C levels in adults in the United States.
Muntner P, Winston J, Uribarri J, Mann D, Fox CS.
Am. J. Med. 2008 Apr;121(4):341-8.
[Text Abstract on PubMed]

On the replication of genetic associations: timing can be everything!
Lasky-Su J, Lyon HN, Emilsson V, Heid IM, Molony C, Raby BA, Lazarus R, Klanderman B, Soto-Quiros ME, Avila L, Silverman EK, Thorleifsson G, Thorsteinsdottir U, Kronenberg F, Vollmert C, Illig T, Fox CS, Levy D, Laird N, Ding X, McQueen MB, Butler J, Ardlie K, Papoutsakis C, Dedoussis G, O'Donnell CJ, Wichmann HE, Celedón JC, Schadt E, Hirschhorn J, Weiss ST, Stefansson K, Lange C.
Am. J. Hum. Genet. 2008 Apr;82(4):849-58.
[Text Abstract on PubMed]

Parental obesity and offspring serum alanine and aspartate aminotransferase levels: the Framingham heart study.
Loomba R, Hwang SJ, O'Donnell CJ, Ellison RC, Vasan RS, D'Agostino, Liang TJ, Fox CS.
Gastroenterology. 2008 Apr;134(4):953-9.
[Text Abstract on PubMed]

Relations of thyroid function to body weight: cross-sectional and longitudinal observations in a community-based sample.
Fox CS, Pencina MJ, D'Agostino RB, Murabito JM, Seely EW, Pearce EN, Vasan RS.
Arch. Intern. Med. 2008 Mar 24;168(6):587-92.
[Text Abstract on PubMed]

Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular disease.
Rutter MK, Wilson PW, Sullivan LM, Fox CS, D'Agostino, Meigs JB.
Circulation. 2008 Feb 26;117(8):1003-9.
[Text Abstract on PubMed]

Pericardial fat, visceral abdominal fat, cardiovascular disease risk factors, and vascular calcification in a community-based sample: the Framingham Heart Study.
Rosito GA, Massaro JM, Hoffmann U, Ruberg FL, Mahabadi AA, Vasan RS, O'Donnell CJ, Fox CS.
Circulation. 2008 Feb 5;117(5):605-13.
[Text Abstract on PubMed]

Impact of impaired fasting glucose on cardiovascular disease: the Framingham Heart Study.
Levitzky YS, Pencina MJ, D'Agostino RB, Meigs JB, Murabito JM, Vasan RS, Fox CS.
J. Am. Coll. Cardiol. 2008 Jan 22;51(3):264-70.
[Text Abstract on PubMed]

Metabolic syndrome, insulin resistance, and brachial artery vasodilator function in Framingham Offspring participants without clinical evidence of cardiovascular disease.
Hamburg NM, Larson MG, Vita JA, Vasan RS, Keyes MJ, Widlansky ME, Fox CS, Mitchell GF, Levy D, Meigs JB, Benjamin EJ.
Am. J. Cardiol. 2008 Jan 1;101(1):82-8.
[Text Abstract on PubMed]

Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies.
Kottgen A, Kao WH, Hwang SJ, Boerwinkle E, Yang Q, Levy D, Benjamin EJ, Larson MG, Astor BC, Coresh J, Fox CS.
BMC Med. Genet. 2008;9:49.
[Text Abstract on PubMed]

Genetics of the Framingham Heart Study population.
Govindaraju DR, Cupples LA, Kannel WB, O'Donnell CJ, Atwood LD, D'Agostino, Fox CS, Larson M, Levy D, Murabito J, Vasan RS, Splansky GL, Wolf PA, Benjamin EJ.
Adv. Genet. 2008;62:33-65.
[Text Abstract on PubMed]

A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets.
Florez JC, Manning AK, Dupuis J, McAteer J, Irenze K, Gianniny L, Mirel DB, Fox CS, Cupples LA, Meigs JB.
Diabetes. 2007 Dec;56(12):3063-74.
[Text Abstract on PubMed]

Association of oxidative stress, insulin resistance, and diabetes risk phenotypes: the Framingham Offspring Study.
Meigs JB, Larson MG, Fox CS, Keaney, Vasan RS, Benjamin EJ.
Diabetes Care. 2007 Oct;30(10):2529-35.
[Text Abstract on PubMed]

Parental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation cohorts.
Parikh NI, Hwang SJ, Larson MG, Cupples LA, Fox CS, Manders ES, Murabito JM, Massaro JM, Hoffmann U, O'Donnell CJ.
Circulation. 2007 Sep 25;116(13):1473-81.
[Text Abstract on PubMed]

Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study.
Pou KM, Massaro JM, Hoffmann U, Vasan RS, Maurovich-Horvat P, Larson MG, Keaney, Meigs JB, Lipinska I, Kathiresan S, Murabito JM, O'Donnell CJ, Benjamin EJ, Fox CS.
Circulation. 2007 Sep 11;116(11):1234-41.
[Text Abstract on PubMed]

Multimarker approach to evaluate the incidence of the metabolic syndrome and longitudinal changes in metabolic risk factors: the Framingham Offspring Study.
Ingelsson E, Pencina MJ, Tofler GH, Benjamin EJ, Lanier KJ, Jacques PF, Fox CS, Meigs JB, Levy D, Larson MG, Selhub J, D'Agostino, Wang TJ, Vasan RS.
Circulation. 2007 Aug 28;116(9):984-92.
[Text Abstract on PubMed]

Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community.
Dhingra R, Sullivan L, Jacques PF, Wang TJ, Fox CS, Meigs JB, D'Agostino RB, Gaziano JM, Vasan RS.
Circulation. 2007 Jul 31;116(5):480-8.
[Text Abstract on PubMed]

Burden and prognostic importance of subclinical cardiovascular disease in overweight and obese individuals.
Ingelsson E, Sullivan LM, Fox CS, Murabito JM, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O'Donnell CJ, Wang TJ, D'Agostino RB, Wolf PA, Vasan RS.
Circulation. 2007 Jul 24;116(4):375-84.
[Text Abstract on PubMed]

Cross-classification of microalbuminuria and reduced glomerular filtration rate: associations between cardiovascular disease risk factors and clinical outcomes.
Foster MC, Hwang SJ, Larson MG, Parikh NI, Meigs JB, Vasan RS, Wang TJ, Levy D, Fox CS.
Arch. Intern. Med. 2007 Jul 9;167(13):1386-92.
[Text Abstract on PubMed]

Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study.
Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, Vasan RS, Murabito JM, Meigs JB, Cupples LA, D'Agostino, O'Donnell CJ.
Circulation. 2007 Jul 3;116(1):39-48.
[Text Abstract on PubMed]

Prevalence and prognostic impact of subclinical cardiovascular disease in individuals with the metabolic syndrome and diabetes.
Ingelsson E, Sullivan LM, Murabito JM, Fox CS, Benjamin EJ, Polak JF, Meigs JB, Keyes MJ, O'Donnell CJ, Wang TJ, D'Agostino, Wolf PA, Vasan RS.
Diabetes. 2007 Jun;56(6):1718-26.
[Text Abstract on PubMed]

The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination.
Splansky GL, Corey D, Yang Q, Atwood LD, Cupples LA, Benjamin EJ, D'Agostino, Fox CS, Larson MG, Murabito JM, O'Donnell CJ, Vasan RS, Wolf PA, Levy D.
Am. J. Epidemiol. 2007 Jun 1;165(11):1328-35.
[Text Abstract on PubMed]

Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring Study.
Wilson PW, Meigs JB, Sullivan L, Fox CS, Nathan DM, D'Agostino.
Arch. Intern. Med. 2007 May 28;167(10):1068-74.
[Text Abstract on PubMed]

Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community.
Dhingra R, Sullivan LM, Fox CS, Wang TJ, D'Agostino, Gaziano JM, Vasan RS.
Arch. Intern. Med. 2007 May 14;167(9):879-85.
[Text Abstract on PubMed]

Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome.
Meigs JB, Rutter MK, Sullivan LM, Fox CS, D'Agostino, Wilson PW.
Diabetes Care. 2007 May;30(5):1219-25.
[Text Abstract on PubMed]

Clinical correlates of circulating visfatin levels in a community-based sample.
Ingelsson E, Larson MG, Fox CS, Yin X, Wang TJ, Lipinska I, Pou KM, Hoffmann U, Benjamin EJ, Keaney, Vasan RS.
Diabetes Care. 2007 May;30(5):1278-80.
[Text Abstract on PubMed]

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.
Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, Meitinger T, Brönner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss ST, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O'Donnell CJ, Vollmert C, Celedón JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN.
PLoS Genet. 2007 Apr 27;3(4):e61.
[Text Abstract on PubMed]

Statin use and sepsis events [corrected] in patients with chronic kidney disease.
Gupta R, Plantinga LC, Fink NE, Melamed ML, Coresh J, Fox CS, Levin NW, Powe NR.
JAMA. 2007 Apr 4;297(13):1455-64.
[Text Abstract on PubMed]

Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study.
Fox CS, Coady S, Sorlie PD, D'Agostino, Pencina MJ, Vasan RS, Meigs JB, Levy D, Savage PJ.
Circulation. 2007 Mar 27;115(12):1544-50.
[Text Abstract on PubMed]

Comparison of anthropometric, area- and volume-based assessment of abdominal subcutaneous and visceral adipose tissue volumes using multi-detector computed tomography.
Maurovich-Horvat P, Massaro J, Fox CS, Moselewski F, O'Donnell CJ, Hoffmann U.
Int J Obes (Lond). 2007 Mar;31(3):500-6.
[Text Abstract on PubMed]

Increasing trends in incidence of overweight and obesity over 5 decades.
Parikh NI, Pencina MJ, Wang TJ, Lanier KJ, Fox CS, D'Agostino RB, Vasan RS.
Am. J. Med. 2007 Mar;120(3):242-50.
[Text Abstract on PubMed]

The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study.
Maia AL, Dupuis J, Manning A, Liu C, Meigs JB, Cupples LA, Larsen PR, Fox CS.
Thyroid. 2007 Mar;17(3):199-202.
[Text Abstract on PubMed]

Gamma glutamyl transferase and metabolic syndrome, cardiovascular disease, and mortality risk: the Framingham Heart Study.
Lee DS, Evans JC, Robins SJ, Wilson PW, Albano I, Fox CS, Wang TJ, Benjamin EJ, D'Agostino RB, Vasan RS.
Arterioscler. Thromb. Vasc. Biol. 2007 Jan;27(1):127-33.
[Text Abstract on PubMed]

The impact of reclassifying moderate CKD as a coronary heart disease risk equivalent on the number of US adults recommended lipid-lowering treatment.
Hyre AD, Fox CS, Astor BC, Cohen AJ, Muntner P.
Am. J. Kidney Dis. 2007 Jan;49(1):37-45.
[Text Abstract on PubMed]

The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports.
Cupples LA, Arruda HT, Benjamin EJ, D'Agostino, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD.
BMC Med. Genet. 2007;8 Suppl 1:S1.
[Text Abstract on PubMed]

A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study.
Hwang SJ, Yang Q, Meigs JB, Pearce EN, Fox CS.
BMC Med. Genet. 2007;8 Suppl 1:S10.
[Text Abstract on PubMed]

Genome-wide association with diabetes-related traits in the Framingham Heart Study.
Meigs JB, Manning AK, Fox CS, Florez JC, Liu C, Cupples LA, Dupuis J.
BMC Med. Genet. 2007;8 Suppl 1:S16.
[Text Abstract on PubMed]

Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project.
Fox CS, Heard-Costa N, Cupples LA, Dupuis J, Vasan RS, Atwood LD.
BMC Med. Genet. 2007;8 Suppl 1:S18.
[Text Abstract on PubMed]

Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.
O'Donnell CJ, Cupples LA, D'Agostino RB, Fox CS, Hoffmann U, Hwang SJ, Ingellson E, Liu C, Murabito JM, Polak JF, Wolf PA, Demissie S.
BMC Med. Genet. 2007;8 Suppl 1:S4.
[Text Abstract on PubMed]

Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes.
Larson MG, Atwood LD, Benjamin EJ, Cupples LA, D'Agostino, Fox CS, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Murabito JM, Newton-Cheh C, O'Donnell CJ, Seshadri S, Vasan RS, Wang TJ, Wolf PA, Levy D.
BMC Med. Genet. 2007;8 Suppl 1:S5.
[Text Abstract on PubMed]

Heritability of the ankle-brachial index: the Framingham Offspring study.
Murabito JM, Guo CY, Fox CS, D'Agostino RB.
Am. J. Epidemiol. 2006 Nov 15;164(10):963-8.
[Text Abstract on PubMed]

Association between well-characterized lipoprotein-related genetic variants and carotid intimal medial thickness and stenosis: The Framingham Heart Study.
Elosua R, Cupples LA, Fox CS, Polak JF, D'Agostino, Wolf PA, O'Donnell CJ, Ordovas JM.
Atherosclerosis. 2006 Nov;189(1):222-8.
[Text Abstract on PubMed]

Cardiovascular disease risk factors in chronic kidney disease: overall burden and rates of treatment and control.
Parikh NI, Hwang SJ, Larson MG, Meigs JB, Levy D, Fox CS.
Arch. Intern. Med. 2006 Sep 25;166(17):1884-91.
[Text Abstract on PubMed]

Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease.
Meigs JB, Wilson PW, Fox CS, Vasan RS, Nathan DM, Sullivan LM, D'Agostino RB.
J. Clin. Endocrinol. Metab. 2006 Aug;91(8):2906-12.
[Text Abstract on PubMed]

BMI modifies associations of IL-6 genotypes with insulin resistance: the Framingham Study.
Herbert A, Liu C, Karamohamed S, Liu J, Manning A, Fox CS, Meigs JB, Cupples LA.
Obesity (Silver Spring). 2006 Aug;14(8):1454-61.
[Text Abstract on PubMed]

Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study.
Fox CS, Pencina MJ, Meigs JB, Vasan RS, Levitzky YS, D'Agostino.
Circulation. 2006 Jun 27;113(25):2914-8.
[Text Abstract on PubMed]

Cross-sectional relations of serum aldosterone and urine sodium excretion to urinary albumin excretion in a community-based sample.
Fox CS, Larson MG, Hwang SJ, Leip EP, Rifai N, Levy D, Benjamin EJ, Murabito JM, Meigs JB, Vasan RS.
Kidney Int. 2006 Jun;69(11):2064-9.
[Text Abstract on PubMed]

Relations of inflammation and novel risk factors to valvular calcification.
Fox CS, Guo CY, Larson MG, Vasan RS, Parise H, O'Donnell CJ, D'Agostino, Keaney, Benjamin EJ.
Am. J. Cardiol. 2006 May 15;97(10):1502-5.
[Text Abstract on PubMed]

Variants at the APOA5 locus, association with carotid atherosclerosis, and modification by obesity: the Framingham Study.
Elosua R, Ordovas JM, Cupples LA, Lai CQ, Demissie S, Fox CS, Polak JF, Wolf PA, D'Agostino, O'Donnell CJ.
J. Lipid Res. 2006 May;47(5):990-6.
[Text Abstract on PubMed]

PAI-1 Gene 4G/5G polymorphism and risk of type 2 diabetes in a population-based sample.
Meigs JB, Dupuis J, Liu C, O'Donnell CJ, Fox CS, Kathiresan S, Gabriel SB, Larson MG, Yang Q, Herbert AG, Wilson PW, Feng D, Tofler GH, Cupples LA.
Obesity (Silver Spring). 2006 May;14(5):753-8.
[Text Abstract on PubMed]

Cross-sectional association of kidney function with valvular and annular calcification: the Framingham heart study.
Fox CS, Larson MG, Vasan RS, Guo CY, Parise H, Levy D, Leip EP, O'donnell CJ, D'Agostino, Benjamin EJ.
J. Am. Soc. Nephrol. 2006 Feb;17(2):521-7.
[Text Abstract on PubMed]

Hemostatic markers of endothelial dysfunction and risk of incident type 2 diabetes: the Framingham Offspring Study.
Meigs JB, O'donnell CJ, Tofler GH, Benjamin EJ, Fox CS, Lipinska I, Nathan DM, Sullivan LM, D'Agostino RB, Wilson PW.
Diabetes. 2006 Feb;55(2):530-7.
[Text Abstract on PubMed]

Sex and age specific effects of chromosomal regions linked to body mass index in the Framingham Study.
Atwood LD, Heard-Costa NL, Fox CS, Jaquish CE, Cupples LA.
BMC Genet. 2006;7:7.
[Text Abstract on PubMed]

Genome-wide linkage analysis to age at natural menopause in a community-based sample: the Framingham Heart Study.
Murabito JM, Yang Q, Fox CS, Cupples LA.
Fertil. Steril. 2005 Dec;84(6):1674-9.
[Text Abstract on PubMed]

Sex-specific association between estrogen receptor-alpha gene variation and measures of adiposity: the Framingham Heart Study.
Fox CS, Yang Q, Cupples LA, Guo CY, Atwood LD, Murabito JM, Levy D, Mendelsohn ME, Housman DE, Shearman AM.
J. Clin. Endocrinol. Metab. 2005 Nov;90(11):6257-62.
[Text Abstract on PubMed]

Genome-wide search for genes affecting serum uric acid levels: the Framingham Heart Study.
Yang Q, Guo CY, Cupples LA, Levy D, Wilson PW, Fox CS.
Metab. Clin. Exp. 2005 Nov;54(11):1435-41.
[Text Abstract on PubMed]

Glycemic status and development of kidney disease: the Framingham Heart Study.
Fox CS, Larson MG, Leip EP, Meigs JB, Wilson PW, Levy D.
Diabetes Care. 2005 Oct;28(10):2436-40.
[Text Abstract on PubMed]

Relations of insulin sensitivity to longitudinal blood pressure tracking: variations with baseline age, body mass index, and blood pressure.
Arnlöv J, Pencina MJ, Nam BH, Meigs JB, Fox CS, Levy D, D'Agostino RB, Vasan RS.
Circulation. 2005 Sep 20;112(12):1719-27.
[Text Abstract on PubMed]

Genomewide linkage analysis of weight change in the Framingham Heart Study.
Fox CS, Heard-Costa NL, Vasan RS, Murabito JM, D'Agostino, Atwood LD, Framingham Heart Study.
J. Clin. Endocrinol. Metab. 2005 Jun;90(6):3197-201.
[Text Abstract on PubMed]

Clinical and genetic correlates of serum aldosterone in the community: the Framingham Heart Study.
Kathiresan S, Larson MG, Benjamin EJ, Corey D, Murabito JM, Fox CS, Wilson PW, Rifai N, Meigs JB, Ricken G, Lifton RP, Levy D, Vasan RS.
Am. J. Hypertens. 2005 May;18(5 Pt 1):657-65.
[Text Abstract on PubMed]

A comparison of death certificate out-of-hospital coronary heart disease death with physician-adjudicated sudden cardiac death.
Fox CS, Evans JC, Larson MG, Lloyd-Jones DM, O'Donnell CJ, Sorlie PD, Manolio TA, Kannel WB, Levy D.
Am. J. Cardiol. 2005 Apr 1;95(7):856-9.
[Text Abstract on PubMed]

Low-grade albuminuria and the risks of hypertension and blood pressure progression.
Wang TJ, Evans JC, Meigs JB, Rifai N, Fox CS, D'Agostino RB, Levy D, Vasan RS.
Circulation. 2005 Mar 22;111(11):1370-6.
[Text Abstract on PubMed]

Genome-wide linkage analysis to urinary microalbuminuria in a community-based sample: the Framingham Heart Study.
Fox CS, Yang Q, Guo CY, Cupples LA, Wilson PW, Levy D, Meigs JB.
Kidney Int. 2005 Jan;67(1):70-4.
[Text Abstract on PubMed]

Trends in cardiovascular complications of diabetes.
Fox CS, Coady S, Sorlie PD, Levy D, Meigs JB, D'Agostino, Wilson PW, Savage PJ.
JAMA. 2004 Nov 24;292(20):2495-9.
[Text Abstract on PubMed]

Kidney function is inversely associated with coronary artery calcification in men and women free of cardiovascular disease: the Framingham Heart Study.
Fox CS, Larson MG, Keyes MJ, Levy D, Clouse ME, Culleton B, O'Donnell CJ.
Kidney Int. 2004 Nov;66(5):2017-21.
[Text Abstract on PubMed]

Genomewide linkage analysis to serum creatinine, GFR, and creatinine clearance in a community-based population: the Framingham Heart Study.
Fox CS, Yang Q, Cupples LA, Guo CY, Larson MG, Leip EP, Wilson PW, Levy D.
J. Am. Soc. Nephrol. 2004 Sep;15(9):2457-61.
[Text Abstract on PubMed]

Temporal trends in coronary heart disease mortality and sudden cardiac death from 1950 to 1999: the Framingham Heart Study.
Fox CS, Evans JC, Larson MG, Kannel WB, Levy D.
Circulation. 2004 Aug 3;110(5):522-7.
[Text Abstract on PubMed]

Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring.
Fox CS, Parise H, D'Agostino, Lloyd-Jones DM, Vasan RS, Wang TJ, Levy D, Wolf PA, Benjamin EJ.
JAMA. 2004 Jun 16;291(23):2851-5.
[Text Abstract on PubMed]

Genome-wide linkage to chromosome 6 for waist circumference in the Framingham Heart Study.
Fox CS, Heard-Costa NL, Wilson PW, Levy D, D'Agostino, Atwood LD.
Diabetes. 2004 May;53(5):1399-402.
[Text Abstract on PubMed]

Undertreatment of hyperlipidemia in a cohort of United States kidney dialysis patients.
Fox CS, Longenecker JC, Powe NR, Klag MJ, Fink NE, Parekh R, Coresh J, CHOICE Study.
Clin. Nephrol. 2004 May;61(5):299-307.
[Text Abstract on PubMed]

Mitral annular calcification is a predictor for incident atrial fibrillation.
Fox CS, Parise H, Vasan RS, Levy D, O'Donnell CJ, D'Agostino RB, Plehn JF, Benjamin EJ.
Atherosclerosis. 2004 Apr;173(2):291-4.
[Text Abstract on PubMed]

Absence of association between polymorphisms in the hemostatic factor pathway genes and carotid intimal medial thickness: the Framingham Heart Study.
Fox CS, Larson MG, Corey D, Feng D, Lindpaintner K, Polak JF, Wolf PA, D'Agostino RB, Tofler GH, O'Donnell CJ.
Stroke. 2004 Mar;35(3):e65-7.
[Text Abstract on PubMed]

The significant effect of diabetes duration on coronary heart disease mortality: the Framingham Heart Study.
Fox CS, Sullivan L, D'Agostino, Wilson PW, Framingham Heart Study.
Diabetes Care. 2004 Mar;27(3):704-8.
[Text Abstract on PubMed]

Predictors of new-onset kidney disease in a community-based population.
Fox CS, Larson MG, Leip EP, Culleton B, Wilson PW, Levy D.
JAMA. 2004 Feb 18;291(7):844-50.
[Text Abstract on PubMed]

Genomewide linkage analysis for internal carotid artery intimal medial thickness: evidence for linkage to chromosome 12.
Fox CS, Cupples LA, Chazaro I, Polak JF, Wolf PA, D'Agostino RB, Ordovas JM, O'Donnell CJ.
Am. J. Hum. Genet. 2004 Feb;74(2):253-61.
[Text Abstract on PubMed]

High prevalence of peripheral arterial disease in persons with renal insufficiency: results from the National Health and Nutrition Examination Survey 1999-2000.
O'Hare AM, Glidden DV, Fox CS, Hsu CY.
Circulation. 2004 Jan 27;109(3):320-3.
[Text Abstract on PubMed]

Mitral annular calcification predicts cardiovascular morbidity and mortality: the Framingham Heart Study.
Fox CS, Vasan RS, Parise H, Levy D, O'Donnell CJ, D'Agostino RB, Benjamin EJ, Framingham Heart Study.
Circulation. 2003 Mar 25;107(11):1492-6.
[Text Abstract on PubMed]

Genetic and environmental contributions to atherosclerosis phenotypes in men and women: heritability of carotid intima-media thickness in the Framingham Heart Study.
Fox CS, Polak JF, Chazaro I, Cupples A, Wolf PA, D'Agostino RA, O'Donnell CJ, Framingham Heart Study.
Stroke. 2003 Feb;34(2):397-401.
[Text Abstract on PubMed]

Evidence for heritability of abdominal aortic calcific deposits in the Framingham Heart Study.
O'Donnell CJ, Chazaro I, Wilson PW, Fox C, Hannan MT, Kiel DP, Cupples LA.
Circulation. 2002 Jul 16;106(3):337-41.
[Text Abstract on PubMed]

Daily energy expenditure in Mexican and USA Pima indians: low physical activity as a possible cause of obesity.
Esparza J, Fox C, Harper IT, Bennett PH, Schulz LO, Valencia ME, Ravussin E.
Int. J. Obes. Relat. Metab. Disord. 2000 Jan;24(1):55-9.
[Text Abstract on PubMed]

Plasma leptin concentrations in Pima Indians living in drastically different environments.
Fox C, Esparza J, Nicolson M, Bennett PH, Schulz LO, Valencia ME, Ravussin E.
Diabetes Care. 1999 Mar;22(3):413-7.
[Text Abstract on PubMed]

Is a low leptin concentration, a low resting metabolic rate, or both the expression of the "thrifty genotype"? Results from Mexican Pima Indians.
Fox CS, Esparza J, Nicolson M, Bennett PH, Schulz LO, Valencia ME, Ravussin E.
Am. J. Clin. Nutr. 1998 Nov;68(5):1053-7.
[Text Abstract on PubMed]

Motor-vehicle crash-injury risk factors among American Indians.
Grossman DC, Sugarman JR, Fox C, Moran J.
Accid Anal Prev. 1997 May;29(3):313-9.
[Text Abstract on PubMed]

Relationships between physical activity, insulin levels and lipids in non-diabetic low income residents of Mexico City: the Mexico City Diabetes Study.
Sowers M, Gonzalez Villalpando C, Stern MP, Fox C, Mitchell BD.
Arch. Med. Res. 1995 Summer;26(2):133-40.
[Text Abstract on PubMed]

Longitudinal association between dairy consumption and changes of body weight and waist circumference: the Framingham Heart Study.
Wang H, Troy LM, Rogers GT, Fox CS, McKeown NM, Meigs JB, Jacques PF.
Int J Obes (Lond)..
[Text Abstract on PubMed]

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