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Caroline Fox, M.D., M.P.H.


CKDGen Meta-Analysis Data


These files contain the summary meta-analysis data from the CKDGen consortium for the following 5 traits:

  1. eGFRcrea (n=67,093)
  2. eGFRcys (n=20,957)
  3. CKD (n=62,237)
  4. UACR (n=31,580)
  5. MA (n=30482)

(These are .csv zipped files)


Within each file, the data are presented as follows:

  • rsID, allele1, allele2, freqA1, direction, pval
  • Allele1=the coded allele
  • Allele2=noncoded allele
  • FreqA1 is the frequency of allele1 from the Hapmap CEU sample
  • Direction refers to the direction of effect for allele1. Can be +/-/0.
  • The p-value is the double GC corrected p-value.


The preferred citations are as follows:

  • For eGFRcrea, eGFRcys, and CKD: Kottgen A, Pattaro C, Boger CA et al. New loci associated with kidney function and chronic kidney disease. Nat Genet 2010 May;42(5):376-84.
  • For UACR and MA: Boger CA, Chen MH, Tin A et al. CUBN Is a Gene Locus for Albuminuria. J Am Soc Nephrol 2011 Mar;22(3):555-70.


Details regarding the case numbers and samples can be found within these published documents. If you have any questions, please contact Dr. Caroline Fox at foxca@nhlbi.nih.gov.

Last Updated: April 26, 2013