Accessible Search Form           Advanced Search

P. Boon Chock, Ph.D.

Publications


Principal Investigator thumbnail image

P. Boon Chock
Senior Investigator

P: +1 301 496 2073
F: +1 301 451 5459
bchock@nih.gov


Full Publications Listing

Mammalian Target of Rapamycin Complex 1 (mTORC1) Plays a Role in Pasteurella multocida Toxin (PMT)-induced Protein Synthesis and Proliferation in Swiss 3T3 Cells.
Oubrahim H, Wong A, Wilson BA, Chock PB.
J Biol Chem. 2013 Jan 25;288(4):2805-15.
[Text Abstract on PubMed]

Pasteurella multocida toxin (PMT) upregulates CTGF which leads to mTORC1 activation in Swiss 3T3 cells.
Oubrahim H, Wong A, Wilson BA, Chock PB.
Cell Signal. 2013 May;25(5):1136-48.
[Text Abstract on PubMed]

RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria.
Tanaka M, Jaruga P, Küpfer PA, Leumann CJ, Dizdaroglu M, Sonntag WE, Boon Chock P.
Free Radic. Biol. Med. 2012 Aug 15;53(4):854-62.
[Text Abstract on PubMed]

Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators.
Chae HZ, Oubrahim H, Park JW, Rhee SG, Chock PB.
Antioxid. Redox Signal. 2012 Mar 15;16(6):506-23.
[Text Abstract on PubMed]

Posttranslational modification of cysteine in redox signaling and oxidative stress: Focus on s-glutathionylation.
Mieyal JJ, Chock PB.
Antioxid. Redox Signal. 2012 Mar 15;16(6):471-5.
[Text Abstract on PubMed]

Structural insights into the catalytic mechanism of Escherichia coli selenophosphate synthetase.
Noinaj N, Wattanasak R, Lee DY, Wally JL, Piszczek G, Chock PB, Stadtman TC, Buchanan SK.
J. Bacteriol. 2012 Jan;194(2):499-508.
[Text Abstract on PubMed]

Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively.
Chung YW, Kim HK, Kim IY, Yim MB, Chock PB.
J. Biol. Chem. 2011 Aug 26;286(34):29681-90.
[Text Abstract on PubMed]

Effect of CCS on the accumulation of FALS SOD1 mutant-containing aggregates and on mitochondrial translocation of SOD1 mutants: implication of a free radical hypothesis.
Kim HK, Chung YW, Chock PB, Yim MB.
Arch. Biochem. Biophys. 2011 May 15;509(2):177-85.
[Text Abstract on PubMed]

FAT10 modifies p53 and upregulates its transcriptional activity.
Li T, Santockyte R, Yu S, Shen RF, Tekle E, Lee CG, Yang DC, Chock PB.
Arch. Biochem. Biophys. 2011 May 15;509(2):164-9.
[Text Abstract on PubMed]

Glutathionylation of peroxiredoxin I induces decamer to dimers dissociation with concomitant loss of chaperone activity.
Park JW, Piszczek G, Rhee SG, Chock PB.
Biochemistry. 2011 Apr 19;50(15):3204-10.
[Text Abstract on PubMed]

SUMOylation of DLX3 by SUMO1 promotes its transcriptional activity.
Duverger O, Chen SX, Lee D, Li T, Chock PB, Morasso MI.
J. Cell. Biochem. 2011 Feb;112(2):445-52.
[Text Abstract on PubMed]

Deglutathionylation of 2-Cys peroxiredoxin is specifically catalyzed by sulfiredoxin.
Park JW, Mieyal JJ, Rhee SG, Chock PB.
J. Biol. Chem. 2009 Aug 28;284(35):23364-74.
[Text Abstract on PubMed]

Novel protective mechanism against irreversible hyperoxidation of peroxiredoxin: Nalpha-terminal acetylation of human peroxiredoxin II.
Seo JH, Lim JC, Lee DY, Kim KS, Piszczek G, Nam HW, Kim YS, Ahn T, Yun CH, Kim K, Chock PB, Chae HZ.
J. Biol. Chem. 2009 May 15;284(20):13455-65.
[Text Abstract on PubMed]

Phagocytic clearance of electric field induced 'apoptosis-mimetic' cells.
Tekle E, Wolfe MD, Oubrahim H, Chock PB.
Biochem. Biophys. Res. Commun. 2008 Nov 14;376(2):256-60.
[Text Abstract on PubMed]

Polyubiquitylation of PARP-1 through ubiquitin K48 is modulated by activated DNA, NAD+, and dipeptides.
Wang T, Simbulan-Rosenthal CM, Smulson ME, Chock PB, Yang DC.
J. Cell. Biochem. 2008 May 1;104(1):318-28.
[Text Abstract on PubMed]

Oxidized messenger RNA induces translation errors.
Tanaka M, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 2007 Jan 2;104(1):66-71.
[Text Abstract on PubMed]

Expression of SUMO-2/3 induced senescence through p53- and pRB-mediated pathways.
Li T, Santockyte R, Shen RF, Tekle E, Wang G, Yang DC, Chock PB.
J. Biol. Chem. 2006 Nov 24;281(47):36221-7.
[Text Abstract on PubMed]

A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers.
Li T, Santockyte R, Shen RF, Tekle E, Wang G, Yang DC, Chock PB.
Arch. Biochem. Biophys. 2006 Sep 1;453(1):70-4.
[Text Abstract on PubMed]

Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis.
Miyoshi N, Oubrahim H, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 2006 Feb 7;103(6):1727-31.
[Text Abstract on PubMed]

Knockout of caspase-like gene, YCA1, abrogates apoptosis and elevates oxidized proteins in Saccharomyces cerevisiae.
Khan MA, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 2005 Nov 29;102(48):17326-31.
[Text Abstract on PubMed]

Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl.
Andoh T, Chock PB, Murphy DL, Chiueh CC.
Mol. Pharmacol. 2005 Nov;68(5):1408-14.
[Text Abstract on PubMed]

Roles of thioredoxin in nitric oxide-dependent preconditioning-induced tolerance against MPTP neurotoxin.
Chiueh CC, Andoh T, Chock PB.
Toxicol. Appl. Pharmacol. 2005 Sep 1;207(2 Suppl):96-102.
[Text Abstract on PubMed]

Effect of bicarbonate on iron-mediated oxidation of low-density lipoprotein.
Arai H, Berlett BS, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 2005 Jul 26;102(30):10472-7.
[Text Abstract on PubMed]

Selective field effects on intracellular vacuoles and vesicle membranes with nanosecond electric pulses.
Tekle E, Oubrahim H, Dzekunov SM, Kolb JF, Schoenbach KH, Chock PB.
Biophys. J. 2005 Jul;89(1):274-84.
[Text Abstract on PubMed]

Induction of thioredoxin and mitochondrial survival proteins mediates preconditioning-induced cardioprotection and neuroprotection.
Chiueh CC, Andoh T, Chock PB.
Ann. N. Y. Acad. Sci. 2005 May;1042:403-18.
[Text Abstract on PubMed]

Glutaredoxin: role in reversible protein s-glutathionylation and regulation of redox signal transduction and protein translocation.
Shelton MD, Chock PB, Mieyal JJ.
Antioxid. Redox Signal. 2005 Mar-Apr;7(3-4):348-66.
[Text Abstract on PubMed]

Molecular cloning and characterization of murine caspase-12 gene promoter.
Oubrahim H, Wang J, Stadtman ER, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 2005 Feb 15;102(7):2322-7.
[Text Abstract on PubMed]

Testis brain ribonucleic acid-binding protein/translin possesses both single-stranded and double-stranded ribonuclease activities.
Wang J, Boja ES, Oubrahim H, Chock PB.
Biochemistry. 2004 Oct 26;43(42):13424-31.
[Text Abstract on PubMed]

Sumoylation of heterogeneous nuclear ribonucleoproteins, zinc finger proteins, and nuclear pore complex proteins: a proteomic analysis.
Li T, Evdokimov E, Shen RF, Chao CC, Tekle E, Wang T, Stadtman ER, Yang DC, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 2004 Jun 8;101(23):8551-6.
[Text Abstract on PubMed]

Biotin-ubiquitin tagging of mammalian proteins in Escherichia coli.
Wang T, Evdokimov E, Yiadom K, Yan Z, Chock PB, Yang DC.
Protein Expr. Purif. 2003 Jul;30(1):140-9.
[Text Abstract on PubMed]

Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt.
Qin S, Chock PB.
Biochemistry. 2003 Mar 18;42(10):2995-3003.
[Text Abstract on PubMed]

Cyclic GMP-dependent protein kinase regulates the expression of thioredoxin and thioredoxin peroxidase-1 during hormesis in response to oxidative stress-induced apoptosis.
Andoh T, Chiueh CC, Chock PB.
J. Biol. Chem. 2003 Jan 10;278(2):885-90.
[Text Abstract on PubMed]

Manganese(II) induces apoptotic cell death in NIH3T3 cells via a caspase-12-dependent pathway.
Oubrahim H, Chock PB, Stadtman ER.
J. Biol. Chem. 2002 Jun 7;277(23):20135-8.
[Text Abstract on PubMed]

Tyrosine phosphatase CD45 regulates hydrogen peroxide-induced calcium mobilization in B cells.
Qin S, Chock PB.
Antioxid. Redox Signal. 2002 Jun;4(3):481-90.
[Text Abstract on PubMed]

Preconditioning-mediated neuroprotection: role of nitric oxide, cGMP, and new protein expression.
Andoh T, Chock PB, Chiueh CC.
Ann. N. Y. Acad. Sci. 2002 May;962:1-7.
[Text Abstract on PubMed]

The roles of thioredoxin in protection against oxidative stress-induced apoptosis in SH-SY5Y cells.
Andoh T, Chock PB, Chiueh CC.
J. Biol. Chem. 2002 Mar 22;277(12):9655-60.
[Text Abstract on PubMed]

Free radicals and disease.
Moskovitz J, Yim MB, Chock PB.
Arch. Biochem. Biophys. 2002 Jan 15;397(2):354-9.
[Text Abstract on PubMed]

Reversible glutathionylation regulates actin polymerization in A431 cells.
Wang J, Boja ES, Tan W, Tekle E, Fales HM, English S, Mieyal JJ, Chock PB.
J. Biol. Chem. 2001 Dec 21;276(51):47763-6.
[Text Abstract on PubMed]

Asymmetric pore distribution and loss of membrane lipid in electroporated DOPC vesicles.
Tekle E, Astumian RD, Friauf WA, Chock PB.
Biophys. J. 2001 Aug;81(2):960-8.
[Text Abstract on PubMed]

Protein glycation: creation of catalytic sites for free radical generation.
Yim MB, Yim HS, Lee C, Kang SO, Chock PB.
Ann. N. Y. Acad. Sci. 2001 Apr;928:48-53.
[Text Abstract on PubMed]

Antioxidant activity of Ferrozine-iron-amino acid complexes.
Berlett BS, Levine RL, Chock PB, Chevion M, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 2001 Jan 16;98(2):451-6.
[Text Abstract on PubMed]

Inositol tetrakisphosphate as a frequency regulator in calcium oscillations in HeLa cells.
Zhu DM, Tekle E, Huang CY, Chock PB.
J. Biol. Chem. 2000 Mar 3;275(9):6063-6.
[Text Abstract on PubMed]

Enzyme-like activity of glycated cross-linked proteins in free radical generation.
Yim MB, Kang SO, Chock PB.
Ann. N. Y. Acad. Sci. 2000;899:168-81.
[Text Abstract on PubMed]

Transcriptional activation of the human manganese superoxide dismutase gene mediated by tetradecanoylphorbol acetate.
Kim HP, Roe JH, Chock PB, Yim MB.
J. Biol. Chem. 1999 Dec 24;274(52):37455-60.
[Text Abstract on PubMed]

Roles of superoxide radical anion in signal transduction mediated by reversible regulation of protein-tyrosine phosphatase 1B.
Barrett WC, DeGnore JP, Keng YF, Zhang ZY, Yim MB, Chock PB.
J. Biol. Chem. 1999 Dec 3;274(49):34543-6.
[Text Abstract on PubMed]

Enhanced free radical generation of FALS-associated Cu,Zn-SOD mutants.
Yim MB, Yim HS, Chock PB, Stadtman ER.
Neurotox Res. 1999 Dec;1(2):91-7.
[Text Abstract on PubMed]

Degradation of alpha-synuclein by proteasome.
Bennett MC, Bishop JF, Leng Y, Chock PB, Chase TN, Mouradian MM.
J. Biol. Chem. 1999 Nov 26;274(48):33855-8.
[Text Abstract on PubMed]

Peroxynitrite-mediated modification of proteins at physiological carbon dioxide concentration: pH dependence of carbonyl formation, tyrosine nitration, and methionine oxidation.
Tien M, Berlett BS, Levine RL, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1999 Jul 6;96(14):7809-14.
[Text Abstract on PubMed]

Oxidation-reduction properties of methylglyoxal-modified protein in relation to free radical generation.
Lee C, Yim MB, Chock PB, Yim HS, Kang SO.
J. Biol. Chem. 1998 Sep 25;273(39):25272-8.
[Text Abstract on PubMed]

Identification of the oxidation states of the active site cysteine in a recombinant protein tyrosine phosphatase by electrospray mass spectrometry using on-line desalting.
DeGnore JP, König S, Barrett WC, Chock PB, Fales HM.
Rapid Commun. Mass Spectrom. 1998;12(20):1457-62.
[Text Abstract on PubMed]

A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.
Yim HS, Kang JH, Chock PB, Stadtman ER, Yim MB.
J. Biol. Chem. 1997 Apr 4;272(14):8861-3.
[Text Abstract on PubMed]

Cloning, characterization and expression of a cDNA clone encoding rabbit ubiquitin-conjugating enzyme, E2(32k).
Sun B, Jeyaseelan K, Chung MC, Tan TW, Chock PB, Teo TS.
Biochim. Biophys. Acta. 1997 Mar 20;1351(1-2):231-8.
[Text Abstract on PubMed]

Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation.
Bae YS, Kang SW, Seo MS, Baines IC, Tekle E, Chock PB, Rhee SG.
J. Biol. Chem. 1997 Jan 3;272(1):217-21.
[Text Abstract on PubMed]

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide.
Yim MB, Kang JH, Yim HS, Kwak HS, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1996 Jun 11;93(12):5709-14.
[Text Abstract on PubMed]

Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide.
Kong SK, Yim MB, Stadtman ER, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1996 Apr 16;93(8):3377-82.
[Text Abstract on PubMed]

Peroxynitrite-mediated nitration of tyrosine residues in Escherichia coli glutamine synthetase mimics adenylylation: relevance to signal transduction.
Berlett BS, Friguet B, Yim MB, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1996 Mar 5;93(5):1776-80.
[Text Abstract on PubMed]

Ubiquitinylation of transcription factors c-Jun and c-Fos using reconstituted ubiquitinylating enzymes.
Hermida-Matsumoto ML, Chock PB, Curran T, Yang DC.
J. Biol. Chem. 1996 Mar 1;271(9):4930-6.
[Text Abstract on PubMed]

Free radicals generated during the glycation reaction of amino acids by methylglyoxal. A model study of protein-cross-linked free radicals.
Yim HS, Kang SO, Hah YC, Chock PB, Yim MB.
J. Biol. Chem. 1995 Nov 24;270(47):28228-33.
[Text Abstract on PubMed]

The tryptophan synthase alpha 2 beta 2 complex: kinetic studies with a mutant enzyme (beta K87T) to provide evidence for allosteric activation by an aminoacrylate intermediate.
Banik U, Zhu DM, Chock PB, Miles EW.
Biochemistry. 1995 Oct 3;34(39):12704-11.
[Text Abstract on PubMed]

Endogenous intracellular glutathionyl radicals are generated in neuroblastoma cells under hydrogen peroxide oxidative stress.
Kwak HS, Yim HS, Chock PB, Yim MB.
Proc. Natl. Acad. Sci. U.S.A. 1995 May 9;92(10):4582-6.
[Text Abstract on PubMed]

Phosphorylation of ubiquitin-activating enzyme in cultured cells.
Cook JC, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1995 Apr 11;92(8):3454-7.
[Text Abstract on PubMed]

Selective and asymmetric molecular transport across electroporated cell membranes.
Tekle E, Astumian RD, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1994 Nov 22;91(24):11512-6.
[Text Abstract on PubMed]

On the protective mechanism of the thiol-specific antioxidant enzyme against the oxidative damage of biomacromolecules.
Yim MB, Chae HZ, Rhee SG, Chock PB, Stadtman ER.
J. Biol. Chem. 1994 Jan 21;269(3):1621-6.
[Text Abstract on PubMed]

Enzyme function of copper, zinc superoxide dismutase as a free radical generator.
Yim MB, Chock PB, Stadtman ER.
J. Biol. Chem. 1993 Feb 25;268(6):4099-105.
[Text Abstract on PubMed]

Isoforms of mammalian ubiquitin-activating enzyme.
Cook JC, Chock PB.
J. Biol. Chem. 1992 Dec 5;267(34):24315-21.
[Text Abstract on PubMed]

Protein ubiquitination is regulated by phosphorylation. An in vitro study.
Kong SK, Chock PB.
J. Biol. Chem. 1992 Jul 15;267(20):14189-92.
[Text Abstract on PubMed]

Kinetic method for differentiating mechanisms for ligand exchange reactions: application to test for substrate channeling in glycolysis.
Wu XM, Gutfreund H, Chock PB.
Biochemistry. 1992 Feb 25;31(7):2123-8.
[Text Abstract on PubMed]

Association of ubiquitin-activating enzyme with HeLa cell chromosomes during mitosis.
Cook JC, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1991 Dec 15;88(24):11388-92.
[Text Abstract on PubMed]

Substrate channeling among glycolytic enzymes: fact or fiction.
Gutfreund H, Chock PB.
J. Theor. Biol. 1991 Sep 7;152(1):117-21.
[Text Abstract on PubMed]

Electroporation by using bipolar oscillating electric field: an improved method for DNA transfection of NIH 3T3 cells.
Tekle E, Astumian RD, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1991 May 15;88(10):4230-4.
[Text Abstract on PubMed]

Distance changes at the regulatory and catalytic sites on Escherichia coli glutamine synthetase: a spin label study on the effect of substrate(s) binding.
Ubom GA, Rhee SG, Hunt JB, Chock PB.
Biochim. Biophys. Acta. 1991 Mar 8;1077(1):91-8.
[Text Abstract on PubMed]

Immunocytochemical localization of ubiquitin-activating enzyme in the cell nucleus.
Cook JC, Chock PB.
Biochem. Biophys. Res. Commun. 1991 Jan 31;174(2):564-71.
[Text Abstract on PubMed]

Substrate channeling in glycolysis: a phantom phenomenon.
Wu XM, Gutfreund H, Lakatos S, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1991 Jan 15;88(2):497-501.
[Text Abstract on PubMed]

Electro-permeabilization of cell membranes: effect of the resting membrane potential.
Tekle E, Astumian RD, Chock PB.
Biochem. Biophys. Res. Commun. 1990 Oct 15;172(1):282-7.
[Text Abstract on PubMed]

Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide.
Yim MB, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1990 Jul;87(13):5006-10.
[Text Abstract on PubMed]

Manganese(II)-bicarbonate-mediated catalytic activity for hydrogen peroxide dismutation and amino acid oxidation: detection of free radical intermediates.
Yim MB, Berlett BS, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1990 Jan;87(1):394-8.
[Text Abstract on PubMed]

Manganese-dependent disproportionation of hydrogen peroxide in bicarbonate buffer.
Stadtman ER, Berlett BS, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1990 Jan;87(1):384-8.
[Text Abstract on PubMed]

Manganese(II) catalyzes the bicarbonate-dependent oxidation of amino acids by hydrogen peroxide and the amino acid-facilitated dismutation of hydrogen peroxide.
Berlett BS, Chock PB, Yim MB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1990 Jan;87(1):389-93.
[Text Abstract on PubMed]

Regulation of Escherichia coli glutamine synthetase.
Rhee SG, Chock PB, Stadtman ER.
Adv. Enzymol. Relat. Areas Mol. Biol. 1989;62:37-92.
[Text Abstract on PubMed]

Ubiquitin: a review on a ubiquitous biofactor in eukaryotic cells.
Cook J, Chock PB.
Biofactors. 1988 Jul;1(2):133-46.
[Text Abstract on PubMed]

Role of cAMP in cyclic cascade regulation.
Shacter E, Stadtman ER, Jurgensen SR, Chock PB.
Meth. Enzymol. 1988;159:3-19.
[Text Abstract on PubMed]

Can free energy be transduced from electric noise?
Astumian RD, Chock PB, Tsong TY, Chen YD, Westerhoff HV.
Proc. Natl. Acad. Sci. U.S.A. 1987 Jan;84(2):434-8.
[Text Abstract on PubMed]

Alteration of intracellular [Ca2+] in sea urchin sperm by the egg peptide speract. Evidence that increased intracellular Ca2+ is coupled to Na+ entry and increased intracellular pH.
Schackmann RW, Chock PB.
J. Biol. Chem. 1986 Jul 5;261(19):8719-28.
[Text Abstract on PubMed]

How enzymes can capture and transmit free energy from an oscillating electric field.
Westerhoff HV, Tsong TY, Chock PB, Chen YD, Astumian RD.
Proc. Natl. Acad. Sci. U.S.A. 1986 Jul;83(13):4734-8.
[Text Abstract on PubMed]

Immunological characterization of phosphoprotein phosphatases.
Shacter E, McClure JA, Korn ED, Chock PB.
Arch. Biochem. Biophys. 1985 Nov 1;242(2):523-31.
[Text Abstract on PubMed]

Inhibition of the Mg(II).ATP-dependent phosphoprotein phosphatase by the regulatory subunit of cAMP-dependent protein kinase.
Jurgensen SR, Chock PB, Taylor S, Vandenheede JR, Merlevede W.
Proc. Natl. Acad. Sci. U.S.A. 1985 Nov;82(22):7565-9.
[Text Abstract on PubMed]

Kinase FA-mediated regulation of rabbit skeletal muscle protein phosphatase. Reversible phosphorylation of the modulator subunit.
Vandenheede JR, Yang SD, Merlevede W, Jurgensen S, Chock PB.
J. Biol. Chem. 1985 Sep 5;260(19):10512-6.
[Text Abstract on PubMed]

Rate-limiting step in the actomyosin adenosinetriphosphatase cycle: studies with myosin subfragment 1 cross-linked to actin.
Stein LA, Greene LE, Chock PB, Eisenberg E.
Biochemistry. 1985 Mar 12;24(6):1357-63.
[Text Abstract on PubMed]

Glutamine synthetase from Escherichia coli.
Rhee SG, Chock PB, Stadtman ER.
Meth. Enzymol. 1985;113:213-41.
[Text Abstract on PubMed]

Regulation through phosphorylation/dephosphorylation cascade systems.
Shacter E, Chock PB, Stadtman ER.
J. Biol. Chem. 1984 Oct 10;259(19):12252-9.
[Text Abstract on PubMed]

Energy consumption in a cyclic phosphorylation/dephosphorylation cascade.
Shacter E, Chock PB, Stadtman ER.
J. Biol. Chem. 1984 Oct 10;259(19):12260-4.
[Text Abstract on PubMed]

Mammalian brain phosphoproteins as substrates for calcineurin.
King MM, Huang CY, Chock PB, Nairn AC, Hemmings, Chan KF, Greengard P.
J. Biol. Chem. 1984 Jul 10;259(13):8080-3.
[Text Abstract on PubMed]

On the mechanism of activation of the ATP X Mg(II)-dependent phosphoprotein phosphatase by kinase FA.
Jurgensen S, Shacter E, Huang CY, Chock PB, Yang SD, Vandenheede JR, Merlevede W.
J. Biol. Chem. 1984 May 10;259(9):5864-70.
[Text Abstract on PubMed]

The rate-limiting step in the actomyosin adenosinetriphosphatase cycle.
Stein LA, Chock PB, Eisenberg E.
Biochemistry. 1984 Mar 27;23(7):1555-63.
[Text Abstract on PubMed]

The apparently negatively cooperative phosphorylation of smooth muscle myosin at low ionic strength is related to its filamentous state.
Sellers JR, Chock PB, Adelstein RS.
J. Biol. Chem. 1983 Dec 10;258(23):14181-8.
[Text Abstract on PubMed]

Protein phosphorylation as a regulatory device.
Shacter-Noiman E, Chock PB, Stadtman ER.
Philos. Trans. R. Soc. Lond., B, Biol. Sci. 1983 Jul 5;302(1108):157-66.
[Text Abstract on PubMed]

Properties of a Mr = 38,000 phosphoprotein phosphatase. Modulation by divalent cations, ATP, and fluoride.
Shacter-Noiman E, Chock PB.
J. Biol. Chem. 1983 Apr 10;258(7):4214-9.
[Text Abstract on PubMed]

Purification and characterization of uridylylated and unuridylylated forms of regulatory protein PII involved in the glutamine synthetase regulation in Escherichia coli.
Rhee SG, Chock PB.
Isozymes Curr. Top. Biol. Med. Res. 1983;8:141-53.
[Text Abstract on PubMed]

Catalytic cycle of the biosynthetic reaction catalyzed by adenylylated glutamine synthetase from Escherichia coli.
Rhee SG, Ubom GA, Hunt JB, Chock PB.
J. Biol. Chem. 1982 Jan 10;257(1):289-97.
[Text Abstract on PubMed]

Subunit cooperation and enzymatic catalysis.
Huang CY, Rhee SG, Chock PB.
Annu. Rev. Biochem. 1982;51:935-71.
[Text Abstract on PubMed]

Allosteric regulation of the state of adenylylation of glutamine synthetase in permeabilized cell preparations of Escherichia coli. Studies of monocyclic and bicyclic interconvertible enzyme cascades, in situ.
Mura U, Chock PB, Stadtman ER.
J. Biol. Chem. 1981 Dec 25;256(24):13022-9.
[Text Abstract on PubMed]

Fluorometric studies of aza-epsilon-adenylylated glutamine synthetase from Escherichia coli.
Rhee SG, Ubom GA, Hunt JB, Chock PB.
J. Biol. Chem. 1981 Jun 25;256(12):6010-6.
[Text Abstract on PubMed]

Mechanism of the actomyosin ATPase: effect of actin on the ATP hydrolysis step.
Stein LA, Chock PB, Eisenberg E.
Proc. Natl. Acad. Sci. U.S.A. 1981 Mar;78(3):1346-50.
[Text Abstract on PubMed]

Mechanism of activation of cyclic nucleotide phosphodiesterase: requirement of the binding of four Ca2+ to calmodulin for activation.
Huang CY, Chau V, Chock PB, Wang JH, Sharma RK.
Proc. Natl. Acad. Sci. U.S.A. 1981 Feb;78(2):871-4.
[Text Abstract on PubMed]

Subunit interaction in unadenylylated glutamine synthetase from Escherichia coli. Evidence from methionine sulfoximine inhibition studies.
Rhee SG, Chock PB, Wedler FC, Sugiyama Y.
J. Biol. Chem. 1981 Jan 25;256(2):644-8.
[Text Abstract on PubMed]

Mechanism of action of troponin . tropomyosin. Inhibition of actomyosin ATPase activity without inhibition of myosin binding to actin.
Chalovich JM, Chock PB, Eisenberg E.
J. Biol. Chem. 1981 Jan 25;256(2):575-8.
[Text Abstract on PubMed]

Interconvertible enzyme cycles in cellular regulation.
Stadtman ER, Chock PB, Rhee SG.
Curr. Top. Cell. Regul. 1981;18:79-94.
[Text Abstract on PubMed]

The nature of negative cooperativity in alkaline phosphatase. Kinetic patterns contrary to the flip-flop model.
Bale JR, Chock PB, Huang CY.
J. Biol. Chem. 1980 Sep 25;255(18):8424-30.
[Text Abstract on PubMed]

Transient kinetic analysis of the catalytic cycle of alkaline phosphatase.
Bale JR, Huang CY, Chock PB.
J. Biol. Chem. 1980 Sep 25;255(18):8431-6.
[Text Abstract on PubMed]

Interconvertible enzyme cascades in cellular regulation.
Chock PB, Rhee SG, Stadtman ER.
Annu. Rev. Biochem. 1980;49:813-43.
[Text Abstract on PubMed]

Subunit interaction of adenylylated glutamine synthetase.
Stadtman ER, Hohman RJ, Davis JN, Wittenberger M, Chock PB, Rhee SG.
Mol Biol Biochem Biophys. 1980;32:144-56.
[Text Abstract on PubMed]

On the mechanism of activation of cyclic mucleotide phosphodiesterase by calmodulin.
Wang JH, Sharma RK, Huang CY, Chau V, Chock PB.
Ann. N. Y. Acad. Sci. 1980;356:190-204.
[Text Abstract on PubMed]

Covalently interconvertible enzyme cascade systems.
Chock PB, Stadtman ER.
Meth. Enzymol. 1980;64:397-325.
[Text Abstract on PubMed]

The mechanism of the skeletal muscle myosin ATPase. II. Relationship between the fluorescence enhancement induced by ATP and the initial Pi burst.
Chock SP, Chock PB, Eisenberg E.
J. Biol. Chem. 1979 May 10;254(9):3236-43.
[Text Abstract on PubMed]

Allosteric regulation of monocyclic interconvertible enzyme cascade systems: use of Escherichia coli glutamine synthetase as an experimental model.
Rhee SG, Park R, Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1978 Jul;75(7):3138-42.
[Text Abstract on PubMed]

Topographical analysis of regulatory and metal ion binding sites on glutamine synthetase from Escherichia coli: 13C and 31P nuclear magnetic resonance and fluorescence energy transfer study.
Villafranca JJ, Rhee SG, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1978 Mar;75(3):1255-9.
[Text Abstract on PubMed]

Interconvertible enzyme cascades in metabolic regulation.
Stadtman ER, Chock PB.
Curr. Top. Cell. Regul. 1978;13:53-95.
[Text Abstract on PubMed]

Direct evidence for separate binding sites for L-Glu and amino acid feedback inhibitors on unadenylylated glutamine synthetase from E. coli.
Rhee SG, Villafranca JJ, Chock PB, Stadtman ER.
Biochem. Biophys. Res. Commun. 1977 Sep 9;78(1):244-50.
[Text Abstract on PubMed]

Superiority of interconvertible enzyme cascades in metabolite regulation: analysis of multicyclic systems.
Chock PB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1977 Jul;74(7):2766-70.
[Text Abstract on PubMed]

Superiority of interconvertible enzyme cascades in metabolic regulation: analysis of monocyclic systems.
Stadtman ER, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1977 Jul;74(7):2761-5.
[Text Abstract on PubMed]

Relaxation studies on complex formation of macrocyclic and open chain antibiotics with monovalent cations.
Chock PB, Eggers F, Eigen M, Winkler R.
Biophys. Chem. 1977 Apr;6(3):239-51.
[Text Abstract on PubMed]

Mechanistic studies of glutamine synthetase from Escherichia coli: kinetics of ADP and orthophosphate binding to the unadenylylated enzyme.
Rhee SG, Chock PB.
Biochemistry. 1976 Apr 20;15(8):1755-60.
[Text Abstract on PubMed]

Mechanistic studies of glutamine synthetase from Escherichia coli: kinetic evidence for two reaction intermediates in biosynthetic reaction.
Rhee SG, Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1976 Feb;73(2):476-80.
[Text Abstract on PubMed]

Mechanistic studies of glutamine synthetase from Escherichia coli. An integrated mechanism for biosynthesis, transferase, ATPase reaction.
Rhee SG, Chock PB, Stadtman ER.
Biochimie. 1976;58(1-2):35-49.
[Text Abstract on PubMed]

Mechanistic studies of glutamine synthetase from Escherichia coli. Fluorometric identification of a reactive intermediate in the biosynthetic reaction.
Timmons RB, Rhee SG, Luterman DL, Chock PB.
Biochemistry. 1974 Oct 22;13(22):4479-85.
[Text Abstract on PubMed]

Epsilon-adenylylated glutamine synthetase: an internal fluorescence probe for enzyme conformation.
Chock PB, Huang CY, Timmons RB, Stadtman ER.
Proc. Natl. Acad. Sci. U.S.A. 1973 Nov;70(11):3134-8.
[Text Abstract on PubMed]

Relaxation study of complex formation between monovalent cations and cyclic polyethers.
Chock PB.
Proc. Natl. Acad. Sci. U.S.A. 1972 Jul;69(7):1939-42.
[Text Abstract on PubMed]

Dimerization of Biebrich scarlet and the monomer-alha-chymorypsin interaction.
Hague DN, Henshaw JS, John VA, Pooley MJ, Chock PB.
Nature. 1971 Jan 15;229(5281):190-1.
[Text Abstract on PubMed]

Relaxation methods and enzymology.
Chock PB.
Biochimie. 1971;53(2):161-72.
[Text Abstract on PubMed]