Accessible Search Form           Advanced Search

Murine Phenotyping Core


Core Facility thumbnail image

Murine Phenotyping Core
Danielle Springer, V.M.D., D.A.C.L.A.M.

Full Publications Listing

Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression.
Wu JJ, Liu J, Chen EB, Wang JJ, Cao L, Narayan N, Fergusson MM, Rovira II, Allen M, Springer DA, Lago CU, Zhang S, DuBois W, Ward T, deCabo R, Gavrilova O, Mock B, Finkel T.
Cell Rep. 2013 Sep 12;4(5):913-20.
[Text Abstract on PubMed]

Increased oxidative metabolism in the Li-Fraumeni syndrome.
Wang PY, Ma W, Park JY, Celi FS, Arena R, Choi JW, Ali QA, Tripodi DJ, Zhuang J, Lago CU, Strong LC, Talagala SL, Balaban RS, Kang JG, Hwang PM.
N Engl J Med. 2013 Mar 14;368(11):1027-32.
[Text Abstract on PubMed]

Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.
Ghosh MC, Zhang DL, Jeong SY, Kovtunovych G, Ollivierre-Wilson H, Noguchi A, Tu T, Senecal T, Robinson G, Crooks DR, Tong WH, Ramaswamy K, Singh A, Graham BB, Tuder RM, Yu ZX, Eckhaus M, Lee J, Springer DA, Rouault TA.
Cell Metab. 2013 Feb 5;17(2):271-81.
[Text Abstract on PubMed]

The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.
Pan X, Liu J, Nguyen T, Liu C, Sun J, Teng Y, Fergusson MM, Rovira II, Allen M, Springer DA, Aponte AM, Gucek M, Balaban RS, Murphy E, Finkel T.
Nat Cell Biol. 2013 Dec 1;15(12):1464-72.
[Text Abstract on PubMed]

Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance.
Tam J, Cinar R, Liu J, Godlewski G, Wesley D, Jourdan T, Szanda G, Mukhopadhyay B, Chedester L, Liow JS, Innis RB, Cheng K, Rice KC, Deschamps JR, Chorvat RJ, McElroy JF, Kunos G.
Cell Metab. 2012 Aug 8;16(2):167-79.
[Text Abstract on PubMed]

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells.
Kim KY, Stevens MV, Akter MH, Rusk SE, Huang RJ, Cohen A, Noguchi A, Springer D, Bocharov AV, Eggerman TL, Suen DF, Youle RJ, Amar M, Remaley AT, Sack MN.
J. Clin. Invest. 2011 Sep;121(9):3701-12.
[Text Abstract on PubMed]

AMPK regulates circadian rhythms in a tissue- and isoform-specific manner.
Um JH, Pendergast JS, Springer DA, Foretz M, Viollet B, Brown A, Kim MK, Yamazaki S, Chung JH.
PLoS ONE. 2011;6(3):e18450.
[Text Abstract on PubMed]

Ambient oxygen promotes tumorigenesis.
Sung HJ, Ma W, Starost MF, Lago CU, Lim PK, Sack MN, Kang JG, Wang PY, Hwang PM.
PLoS ONE. 2011;6(5):e19785.
[Text Abstract on PubMed]

Ablation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesis.
Ma X, Jana SS, Conti MA, Kawamoto S, Claycomb WC, Adelstein RS.
Mol. Biol. Cell. 2010 Nov 15;21(22):3952-62.
[Text Abstract on PubMed]

The renal artery ostium flow diverter: structure and potential role in atherosclerosis.
Neufeld EB, Yu ZX, Springer D, Yu Q, Balaban RS.
Atherosclerosis. 2010 Jul;211(1):153-8.
[Text Abstract on PubMed]

Dietary nitrate and nitrite modulate blood and organ nitrite and the cellular ischemic stress response.
Raat NJ, Noguchi AC, Liu VB, Raghavachari N, Liu D, Xu X, Shiva S, Munson PJ, Gladwin MT.
Free Radic. Biol. Med. 2009 Sep 1;47(5):510-7.
[Text Abstract on PubMed]

Retrospective analysis of wound characteristics and tetanus development in captive macaques.
Springer DA, Phillippi-Falkenstein K, Smith G.
J. Zoo Wildl. Med. 2009 Mar;40(1):95-102.
[Text Abstract on PubMed]

p21Cip1 modulates arterial wound repair through the stromal cell-derived factor-1/CXCR4 axis in mice.
Olive M, Mellad JA, Beltran LE, Ma M, Cimato T, Noguchi AC, San H, Childs R, Kovacic JC, Boehm M.
J. Clin. Invest. 2008 Jun;118(6):2050-61.
[Text Abstract on PubMed]

Effect of ketamine anesthesia on daily food intake in Macaca mulatta and Cercopithecus aethiops.
Springer DA, Baker KC.
Am. J. Primatol. 2007 Oct;69(10):1080-92.
[Text Abstract on PubMed]

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.
Hsu LL, Champion HC, Campbell-Lee SA, Bivalacqua TJ, Manci EA, Diwan BA, Schimel DM, Cochard AE, Wang X, Schechter AN, Noguchi CT, Gladwin MT.
Blood. 2007 Apr 1;109(7):3088-98.
[Text Abstract on PubMed]

Frequency of feeding enrichment and response of laboratory nonhuman primates to unfamiliar people.
Baker KC, Springer DA.
J. Am. Assoc. Lab. Anim. Sci. 2006 Jan;45(1):69-73.
[Text Abstract on PubMed]

PHI-1 induced enhancement of myosin phosphorylation in chicken smooth muscle.
El-Touhky A, Given AM, Cochard A, Brozovich FV.
FEBS Lett. 2005 Aug 15;579(20):4271-7.
[Text Abstract on PubMed]