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NHLBI Small Business Program


The NHLBI Small Business Program enables US-owned and operated small businesses to engage in research and development on innovative and commercially promising products and services to prevent, diagnose, and treat heart, lung, and blood-related diseases and disorders.

Funding for small business research is available through the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) mechanisms. For an overview of these mechanisms, please visit ABOUT THE PROGRAMS. You can also explore current NHLBI SBIR/STTR funding opportunities here.

Staff from the NHLBI Office of Translational Alliances and Coordination (OTAC), are available to advise and mentor NHLBI SBIR/STTR applicants and awardees on matters relating to product development, regulatory affairs, intellectual property, product commercialization, licensing, and strategic partnerships.

We strongly encourage prospective SBIR/STTR applicants to contact us to discuss their planned funding proposals. Please visit OTAC’s website to learn more about the services that our office offers.

Latest Announcements

Meet with FDA: Regulatory Support for Innovative Medical Devices

Are you developing a technologically innovative or substantial risk medical device (diagnostic or therapeutic)? Apply by August 15, 2016 for an administrative supplement to your NHLBI SBIR/STTR award for support to engage in an early face-to-face meeting with the FDA Center for Devices and Radiological Health (CDRH). Read the full announcement (PA-16-335) and reach out to NHLBI Regulatory Specialist Chris Sasiela ( for more information.

Get Tips on Your Commercialization Plan and Regulatory Strategy

Watch the NHLBI Small Biz Hangouts. Check out archived presentationsexternal disclaimer

Archives of What's New

Last Updated May 2016

Connect with Us!

Tel: 301-496-2149

Inquiry Form:
NHLBI Small Biz Inquiry Form

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Upcoming Events

7/11 NIH Day Hosted by Kentucky Science and Technology Corporation external disclaimer - Webinar 

9/13 RESI 2016 external disclaimer - Boston, MA 

9/19 - 9/20 Arizona Bioscience Week (AZBio) external disclaimer - Phoenix, AZ 

9/29 14th Annual Dartmouth Device Development Symposium external disclaimer - Woodstock, VT 

10/17 AdvaMed 2016 external disclaimer - Minneapolis, MN 

10/18BIO Investor Forum external disclaimer - San Francisco, CA 

11/1NHLBI Innovation Conference - New York, NY 

11/1 - 11/3SSTi 2016 Annual Conference external disclaimer - Col - Columbus, OH 

11/2 - 11/3Life Sciences Summitexternal disclaimer - New York, NY 

11/13 - 11/15Partnering for Cures external disclaimer - New York, NY 

11/15 - 11/17 18th Annual HHS SBIR/STTR Conference external disclaimer - Orlando, FL 



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