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NHLBI SBIR Phase IIB Bridge Awards

Application Due Dates: June 20, 2016; June 19, 2017
Letter of Intent Due Dates: May 20, 2016; May 19, 2017
Read about updates to the Phase IIB Bridge Award funding opportunity in NOT-HL-16-317

Register for the informational webinar on May 4, 2016: of external icon

About the Bridge Award

The purpose of the NHLBI SBIR Phase IIB Bridge Award is to facilitate and accelerate the capital-intensive steps that are required to transition SBIR/STTR Phase II projects to the commercialization stage by promoting partnerships between SBIR/STTR Phase II awardees and third-party investors and/or strategic partners. The Bridge Award encourages business relationships between applicant small business concerns and third-party investors/strategic partners who can provide substantial financing to help accelerate the commercialization of promising new products and technologies that were initiated with SBIR/STTR funding. In particular, applicants are expected to leverage their previous SBIR/STTR support, as well as the opportunity to compete for additional funding through the NHLBI Bridge Award program, to attract and negotiate third-party financing needed to advance a product or technology toward commercialization. The applicant’s ability to secure independent third-party investor funds that equal or exceed the total amount of the NHLBI funds being requested over the entire Bridge Award project period will help to validate the commercial potential that is essential for the SBIR projects solicited under the Bridge Award program. It is anticipated that many of the partnerships between small businesses and third-party investors will involve a considerable level of project due diligence by the private sector, thereby increasing the likelihood of commercial success for the funded projects. In light of these goals, the NHLBI strongly encourages applicants to establish business relationships with investors, strategic partners or both that have appropriate prior experience in commercializing emerging biomedical technologies.

Projects proposed in response to this FOA must require eventual Federal regulatory approval/clearance, and may address preclinical and/or clinical stages of technology development. Budgets up to $3 million in total costs over three years may be requested. Development efforts may include preclinical R&D, which is needed for regulatory filings (e.g., IND or IDE) and/or clinical trials.

Projects focused on rare diseases or young pediatric populations may be eligible for the SBIR Phase IIB Small Market Award program. Read more here.


An SBIR Phase IIB Bridge Award application must represent a continuation of the research and development efforts performed under a previously funded SBIR or STTR Phase II grant or contract award. The NHLBI welcomes applicants previously funded by any NIH Institute or Center or any other Federal agency, as long as the proposed work applies to the NHLBI mission. Applications may be predicated on a previously funded SBIR or STTR Phase II grant or contract award.*

*NOTE: Applicants who intend to submit an application that is predicated on an SBIR Phase II contract or any Phase II award from another Federal agency MUST contact the NHLBI prior to submission, so that the NHLBI can properly arrange for such applications to be accepted. See NIH SBIR FAQ page for additional information on submitting a grant application based on a contract award or award from another agency.

Learn more

To learn more about the NHLBI SBIR Phase IIB Bridge Award program and how to apply, read the Funding Opportunity Announcement or contact us.

Last Updated April 2016

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