075 Dedicated Pediatric Cardiac MRI Receive Coils
Annual Phase I Contract Solicitation
(Fast-Track proposals will be accepted.)
Number of anticipated awards: 1
Budget (total costs): Phase I: $225,000
for 12 months; Phase II: $600,000 for 1 year
It is strongly suggested that proposals
adhere to the above budget amounts and project periods. Proposals
with budgets exceeding the above amounts and project periods may not
Clinical MRI systems use local surface
receive devices (coils) to provide optimized signal to noise and
enable fast imaging using parallel imaging techniques. These surface
coils are designed for adult patients and function poorly for
pediatric patients. Pediatric coils are targeted at a certain age
group and due to the wide range of pediatric patient sizes (from
neonates to preadolescents) it is not possible to design one set of
surface coils that fit all pediatric patients. In this solicitation
we seek a set of dedicated cardiac MRI coils that will cover the
entire range of pediatric patients.
The aim is to create a set of four (4)
different pediatric cardiac MRI receive coil arrays to cover the
size ranges of the pediatric population: 1) Neonate/Premie, 2) 3
months Š 2 years, 3) 4-8 years, 4) 10-12 years. The coils could
consist of a semi-rigid shell in the shape of the pediatric torso
and multiple receiver coil elements will be placed on the shell.
Optimal design in terms of coil element sizes and placement needs to
be determined (through simulation and prototyping) during the
project. The goal is to have coils with a large number of coil
elements (16-64) optimized for parallel imaging (rate 4 for 2D
imaging and rates 4-8 for 3D imaging). We envision an iterative
development process where prototype coils are refined and optimized
based on actual experiments in pediatric patients at the NHLBI
operated MRI system at ChildrenÕs National Medical Center (Phase I).
Commercial products will be developed based on the prototypes (Phase
Phase I Activities and Expected
Phase I will be focused on developing and
fine-tuning prototypes. The end goal of the project (after phase II)
is to have a commercial set of 4 coils, but for phase I, two (2)
coils will be expected (e.g. sizes 1 and 4 above). Phase I will be
initiated with discussions between the vendor and NHLBI about coil
sizes, element counts, and parallel imaging performance
expectations. The deliverables for Phase I are:
- Initial survey of reasonable coil geometries for the 4 body
sizes mentioned above.
- Simulations of optimal element size and count for all 4 coil
- Two prototype coils (sizes 1 and 4). Compatible with a
Siemens 64-channel, 1.5T Aera MRI system (Dual Density Signal
- Coil test data needed for a) Siemens safety compliance, b)
NHLBI NMR Safety Committee approval for human use.
Phase II Activities and Expected
Phase II represents the final
commercialization of the set of four (4) coils. Expected
- One set of (4) coils approved for human use.
For more information, see the FY2013 Contract Solicitation or contact OTAC.
Questions and responses pertaining to this topic are available.
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Last Updated August 2012