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064 Novel Technologies for Assessing Lipoprotein Sub-fractions
NHLBI SBIR/STTR Contract Topic
(Fast-Track proposals will be accepted.)
Number of anticipated awards: 1-2
Identifying cardiovascular risk factors and understanding the contribution of those risk factors for cardiovascular disease is critical. Identifying individuals at very high risk for CVD and aggressive intervention are a critical factor to minimize the population wide CVD burden. Determining low density lipoprotein (LDL) as well as high density lipoprotein (HDL) particle size distribution may provide additional predictive power to LDL or HDL cholesterol measurement alone to estimate an individual’s risk for CVD. Current systems that can quantify the lipoprotein sub-fractions are labor intensive and need long turnaround time and thus are not practical for routine clinical applications.
Offerors will develop novel technologies for accurate, high throughput measurement of lipoprotein sub-fractions and use the developed technology to study the value of diagnostic performance in CVD.
Phase I proposals should address initial
development and feasibility testing of novel
lipoprotein sub-fraction measurements.
For more information, contact OTAC.
Last Updated December 2011