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NHLBI SBIR/STTR

NHLBI SBIR/STTR Funding Opportunities

Funding Opportunities

The following links provide detailed information on the different types of funding opportunities for which small businesses can apply.

Highlighted Funding Opportunities

  • Skip Phase I and apply directly for a Phase II grant
    It is now possible to apply directly for a Phase II grant if you already have preliminary data equivalent to what would normally be done in a Phase I award. Learn more about this new opportunity.

  • NHLBI Small Market Award
    Up to $1 million per year for three years to support the next stage of development for technologies addressing rare diseases or pediatric populations. Learn more.

  • NHLBI Bridge Award
    Up to $1 million per year for three years to support the next stage of development for previously funded SBIR Phase II projects. Learn more.

  • Commercialize NIH Technologies through the SBIR-TT Program
    Get funded to develop NHLBI intramural innovations! The NHLBI is seeking small business applications to transfer technologies out of NHLBI intramural research labs into the private sector. Projects should address mechanisms, diseases, or disorders within the NHLBI mission. Read more.

General SBIR/STTR Funding Information

The NHLBI provides numerous funding opportunities for small business concerns (SBCs), using grant and contract mechanisms, and supporting targeted research areas and investigator-initiated applications.

The SBIR/STTR program is structured in three phases. The main objective in Phase I is for SBCs to establish the technical merit and feasibility of the proposed research and development (R&D) efforts, while in Phase II it is to continue the R&D efforts initiated in Phase I. The objective of Phase III is for the SBC to pursue with non-SBIR funds the commercialization of the product or service developed during its Phase II activities.

The STTR program requires a partnership between the small business and a non-profit US research institution. The small business must perform at least 40% of the work, and the research institution must perform at least 30%.

Basic information on each of the phases is described below. For more information, see About the Programs:

  • Phase I: Funding for proof-of-concept or feasibility studies. Generally, up to $225,000 for six months (SBIR) to one year (STTR).
  • Phase II: Funding for continued R&D effort: Generally, up to $1,500,000 for two years.
  • SBIR Phase IIB: The NHLBI is no longer participating in the Phase IIB program through the NIH Omnibus Grant Solicitation. The NHLBI offers Phase IIB funding through two RFAs: The Bridge Awards and the Small Market Awards.

How to Apply

To learn more about applying for funding from the National Institutes of Health (NIH), necessary forms, important deadlines, a general timeline, and guidelines for tracking your application through the process, click here.

Last Updated October 2014

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