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Human Embryonic Stem Cell Research Guide for NHLBI Investigators
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On March 9, 2009, President Barack Obama issued Executive Order 13505, "Removing Barriers to Responsible Scientific Research Involving Human Stem Cells." On July 7, 2009 the NIH issued Guidelines for Human Stem Cell Research that provided NIH-funded researchers with access to human embryonic stem cell (hESC) lines by establishing an NIH Human Embryonic Stem Cell Registry. The Guidelines also establish the eligibility criteria for hESC line to be posted on the Registry.
Cell Lines Permitted for hESC Research
If your research project grant was funded before April 17, 2009
If your research project grant was funded on or after April 17, 2009
As you are identifying cell lines on the NIH Registry, note that selected lines may be:
Information for hESC Research
Investigators with questions about NIH-supported hESC research may contact Dr. John Thomas for current information on this research area.
NIH Human Embryonic Stem Cell Registry
The NIH has developed its current NIH Human Embryonic Stem Cell Registry comprised of lines that have been submitted, reviewed and judged eligible for use in NIH-funded research per the 2009 NIH Guidelines on Human Stem Cell Research. For more information on this process, please refer to NOT-OD-10-020 (December 2, 2009) "First Human Embryonic Stem Cells Approved for use under the NIH Guidelines for Human Stem Cell Research."
Stem Cell Information
The NIH Stem Cell Information web site contains numberous links that may be useful to experienced researchers as well as to those planning their first research project that involves stem cells. Resources include information on submitting hESC lines to the NIH Registry to basic information on stem cells plus links to current research as well as information to upcoming hESC training courses.
Dr. John W. Thomas
Last Updated: April 21, 2010
For questions and/or concerns regarding the content of this page, please contact the Clinical Research Policy Manager