FYI from the NHLBI Index

January 2010: Vol. 10, Issue 3
Research and Resources

Functional Modeling of Pediatric Upper Airway Disorders (R01)
Lung Transplantation: Planning Grants for Clinical Trials of Novel Therapies (R34)
Bioengineering Nanotechnology Initiative (STTR [R41/R42]) and (SBIR [R43/R44])
NHLBI Clinical Trial Pilot Studies (R34)
Bioengineering Research Grants (R01 and R21)
Cellular and Molecular Mechanisms of Arterial Stiffening and Its Relationship to Development of Hypertension (R01)
NHLBI Centers for Cardiovascular Outcomes Research (U01)
Obesity Policy Research: Evaluation and Measures (R01)
Effectiveness Research on Smoking Cessation in Hospitalized Patients (U01)
Selected Topics in Transfusion Medicine (R01/R21)
Reducing Cardiovascular Disease Risk Through Treatment of Obstructive Sleep Apnea (U34)
Critical Illness and Injury in Aging (R01)
Dissemination and Implementation Research in Health (R01)
Development of Multifunctional Drug and Gene Delivery Systems (R01)
Programs of Excellence in Glycosciences (P01)
Systems Biology Approach to the Mechanisms of TB Latency and Reactivation (R01)

NHLBI Research Initiatives

From time to time, the NHLBI invites investigators to submit grant applications or contract proposals for specific research programs. We are soliciting applications for the new programs described below. Please visit the URL listed with each program to obtain information about important application dates and deadlines. For full details of these and other current research initiatives, visit www.nhlbi.nih.gov/funding/inits/index.htm.

Functional Modeling of Pediatric Upper Airway Disorders (R01)

Initiative Number: RFA-HL-10-017
Objective: Develop functional computational models of the upper airway in children with multiple types of congenital malformations and acquired syndromes of airway obstruction to identify control points that limit airflow.

Lung Transplantation: Planning Grants for Clinical Trials of Novel Therapies (R34)

Initiative Number: RFA-HL-10-016
Objective: Propose novel protocols assessing promising new interventions for lung donors and recipients with the goal of improving long-term lung transplant patient outcomes.

Bioengineering Nanotechnology Initiative (STTR [R41/R42]) and (SBIR [R43/R44])

Initiative Number: PA-09-266 and -267
Objective: Conduct small business projects that develop and apply nanotechnology to biomedicine.

NHLBI Clinical Trial Pilot Studies (R34)

Initiative Number: PAR-10-005
Objective: Conduct pilot studies to obtain critical data needed to design clinical trials directed at improving the prevention and treatment of heart, lung, blood, and sleep disorders.

Bioengineering Research Grants (R01 and R21)

Initiative Number: PA-10-009 and -010
Objective: Conduct basic design-directed or hypothesis-driven bioengineering studies in single laboratories or small groups using integrative, systems approaches.

Cellular and Molecular Mechanisms of Arterial Stiffening and Its Relationship to Development of Hypertension (R01)

Initiative Number: RFA-HL-10-027
Objective: Determine the relationship between arterial stiffening and the development of hypertension with the goal of preventing hypertension and associated target organ damage.

NHLBI Centers for Cardiovascular Outcomes Research (U01)

Initiative Number: RFA-HL-10-008 and -018
Objective: Generate an improved understanding of the processes involved in translating cardiovascular research findings into practice through the conduct of outcomes and comparative effectiveness research.

Obesity Policy Research: Evaluation and Measures (R01)

Initiative Number: PA-10-027 and -028
Objective: Conduct research on community and other population-level public policy interventions that may affect diet and physical activity.

Effectiveness Research on Smoking Cessation in Hospitalized Patients (U01)

Initiative Number: RFA-HL-10-020 and -025
Objective: Conduct studies to determine how to translate smoking cessation interventions for hospitalized patients into effective programs for implementation in routine clinical care and to assess their cost effectiveness.

Selected Topics in Transfusion Medicine (R01/R21)

Initiative Number: PAR-10-033 and -034
Objective: Conduct research on selected topics related to transfusion medicine, such as alloimmunization and its consequences, infectious disease complications, microchimerism, the development of effective animal models of transfusion complications, and behavioral studies related to blood donor recruitment.

Reducing Cardiovascular Disease Risk Through Treatment of Obstructive Sleep Apnea (U34)

Initiative Number: RFA-HL-10-023
Objective: Provide preliminary and critical information for the design of a Phase III clinical trial to test whether positive airway pressure treatment of obstructive sleep apnea reduces cardiovascular events.

Critical Illness and Injury in Aging (R01)

Initiative Number: PA-10-042, -043, and -044
Objective: Study mechanisms and management of critical illness and injury, including trauma and neurotrauma, in aging.

Dissemination and Implementation Research in Health (R01)

Initiative Number: PAR-10-038
Objective: Identify, develop, and refine methods to test models of dissemination and implementation of health behavior change interventions and evidence-based prevention.

Development of Multifunctional Drug and Gene Delivery Systems (R01)

Initiative Number: PAR-10-048
Objective: Develop drug and gene delivery systems that can target therapies to particular cells and intracellular components.

Programs of Excellence in Glycosciences (P01)

Initiative Number: RFA-HL-10-026
Objective: Enhance interdisciplinary research and training in glycosciences in order to translate emerging discoveries in glycosciences into new diagnostics and clinical applications.

Systems Biology Approach to the Mechanisms of TB Latency and Reactivation (R01)

Initiative Number: RFA-HL-10-015 and -022
Objective: Investigate the mechanisms of latency and reactivation of tuberculosis in the lung using collaborative systems biology approaches based primarily on human studies.

Modified 1/15/10
[Back to Top]
[Table of Contents]

Need More Information?

We are always interested in receiving comments and suggestions from the community. If you or your organizations have questions for me or for the Institute, please contact me at shurinsb@nhlbi.nih.gov or Dr. Carl Roth at rothc@nhlbi.nih.gov.

Susan B. Shurin, M.D.
Acting Director, NHLBI

For information on specific issues, the following contacts may be helpful:

For health related questions and publications, please contact the trained information specialists at the NHLBI Information Center (NHLBIinfo@nhlbi.nih.gov) or write to the Information Center at P.O. Box 30105, Bethesda, MD 20824-0105.

For communications pertaining to NHLBI policies and priorities, contact the NHLBI Office of Public Liaison, (nhlbi.listens@nih.gov).

For additional information regarding NHLBI events, consult the references provided or NHLBI Calendar. Most other NIH Institutes and Centers also maintain calendars on their Web sites. Links to their Web pages are at NIH Institutes, Centers, and Offices.

For Web related matters pertaining to the online version of the FYI from the NHLBI, contact the FYI from the NHLBI's Web Editor.

Please send us your feedback, comments, and questions by using the appropriate link on the page, Contact the NHLBI.

Note to users of screen readers and other assistive technologies: please report your problems here.