FYI from the NHLBI Index

December 2001: Vol. 2, Issue 3
Research and Resources

    Landmark Framingham Heart Study Recruits Third Generation

    Spotlight on Our Web Site - Heart-Healthy Recipes from the Obesity Education Initiative

    New NHLBI Research Initiatives

    • Basic Research to Improve Cardiopulmonary and Neurological Outcomes Following Resuscitation from Cardiopulmonary Arrest
    • Cellular and Molecular Mechanisms of Primary Pulmonary Hypertension
    • Centers for Reducing Asthma Disparities
    • Functional Tissue Engineering for Heart, Vascular, Lung, Blood, and Sleep Disorders and Diseases
    • Innovative Concepts and Approaches to Developing Functional Tissues and Organs for Heart, Vascular, Lung, and Blood Applications: Exploratory/ Developmental Research Grants
    • Interaction of Genes and Environment in Shaping Risk Factors for Heart, Lung, Blood, and Sleep Disorders
    • NHLBI Innovative Research Grant Program
    • NHLBI Shared Microarray Facilities
    • Novel Biomarkers of Chronic Obstructive Pulmonary Disease (COPD)
    • Pathogenesis and Treatment of Lymphedema
    • Physical Activity and Obesity Across Chronic Diseases
    • Restless Legs Syndrome and Periodic Limb Movement Disorder
    • Role of Infectious Agents in the Development of Vascular Disease
    • SBIR/STTR Technologies for Monitoring and Performing Resuscitation
    • Transfusion Medicine/Hemostatis Clinical Research Network

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Landmark Framingham Heart Study Recruits Third Generation

The Framingham Heart Study (FHS) - which helped give the world the term "risk factors" to describe behaviors or conditions that increase the chance of disease - is about to begin recruiting its third generation of participants. Researchers plan to enroll about 3,500 grandchildren of the study's 5,209 original participants, recruitment of whom began in 1948. In 1971, the Framingham Offspring Study was created, adding 5,124 men and women (children of the original participants) and their spouses.

Key goals of the Third Generation Study are to:

"Expanding to a third generation opens up the chance to explore important new questions about disease risk, especially those related to genetics," said Dr. Lenfant. "We've come a long way in our understanding of what influences the disease process, and that knowledge has contributed to dramatic declines in deaths from heart disease and stroke. But these are complicated diseases and many questions remain unanswered. With the help of another generation, FHS may close in on the root causes of cardiovascular disease and lead to improvements in how we prevent, diagnose, and treat cardiovascular disease."

"The collaboration between FHS scientists and participants has been remarkable," said FHS Director Dr. Daniel Levy. "The study has been possible only because of the participants' dedication. All of our discoveries are their gift to the world."

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Spotlight on Our Web Site

Aim For A Healthy Weight
Traditionally, December holidays are celebrated with festivities that include friends, family and, of course, food. This month, we are featuring the NHLBI's Obesity Education Initiative's Web site, which includes tips for maintaining your healthy eating habits when dining out and links to three popular collections of heart healthy recipes.

The 32-page cookbook Heart-Healthy Home Cooking African American Style includes a recipe for candied yams that is sure to sweeten your dinner without adding much fat.

Try Heart-Healthy Versions of Your Favorite Foods

You don't have to hablar español to serve dishes from the bilingual Platillos Latinos ¡Sabrosos y Saludables! (Delicious Heart-Healthy Latino Recipes) cookbook; consider substituting a fresh cabbage and tomato salad for coleslaw.

But don't overindulge just because the garlic mashed potatoes, green beans sauté, and crunchy pumpkin pie came from the Stay Young at Heart collection. Low in fat does not mean low in calories, and reducing dietary fat alone without reducing calories will not help you lose weight.

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New NHLBI Research Initiatives

From time to time, the NHLBI invites investigators to submit grant applications or contract proposals for specific research programs. We are currently soliciting applications for the programs described below. For a full details of these and other research initiatives, visit http://www.nhlbi.nih.gov/funding/inits/index.htm or the Web page that are linked each initiative number.

Basic Research to Improve Cardiopulmonary and Neurological Outcomes Following Resuscitation from Cardiopulmonary Arrest

Cellular and Molecular Mechanisms of Primary Pulmonary Hypertension

Centers for Reducing Asthma Disparities

Functional Tissue Engineering for Heart, Vascular, Lung, Blood, and Sleep Disorders and Diseases

Innovative Concepts and Approaches to Developing Functional Tissues and Organs for Heart, Vascular, Lung, and Blood Applications: Exploratory/ Developmental Research Grants

Interaction of Genes and Environment in Shaping Risk Factors for Heart, Lung, Blood, and Sleep Disorders

NHLBI Innovative Research Grant Program

NHLBI Shared Microarray Facilities

Novel Biomarkers of Chronic Obstructive Pulmonary Disease (COPD)

Pathogenesis and Treatment of Lymphedema

Physical Activity and Obesity Across Chronic Diseases

Restless Legs Syndrome and Periodic Limb Movement Disorder

Role of Infectious Agents in the Development of Vascular Disease

SBIR/STTR Technologies for Monitoring and Performing Resuscitation

Transfusion Medicine/Hemostatis Clinical Research Network

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Need More Information?

For health related questions and publications, please contact the trained information specialists at the NHLBI Information Center.


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