May 5, 2014
Health and financial analysis reinforces NIH's decision to fund Women's Health Initiative
An in-depth analysis of final data from one of the Women’s Health Initiative (WHI) Postmenopausal Hormone Therapy Trials has found that the investment in WHI resulted in a return of $140 in net economic value for each dollar invested in the trial.
May 1, 2014
: The Columbus Dispatch
Huge study saved lives and closed gender gap in research
It has been credited with preventing thousands of cases of breast cancer. It has confounded medical experts on everything from diet to hormone therapy. But the NHLBI-supported Women’s Health Initiative also has cut through some of the clutter of smaller medical studies that offer contradictory conclusions about what’s best for women’s health.
May 1, 2014
: Fred Hutchinson Cancer Research Center
Women's Health Initiative conference draws researchers from around the U.S.
More than 100 researchers from around the country will gather at Fred Hutchinson Cancer Research Center Thursday and Friday for the Annual Women’s Health Initiative Investigator meeting. Fred Hutch is the coordinating center for the WHI, which currently involves 10 regional research centers nationwide.
October 18, 2013
Women’s Health Initiative reaffirms use of short-term hormone replacement therapy for younger women
Investigators from the Women’s Health Initiative (WHI) Hormone Trials are reaffirming conclusions that hormone therapy is not recommended for the prevention of chronic disease, but may remain a reasonable option for the short-term management of menopausal symptoms for younger women. Investigators reached this conclusion after reviewing data from the trial and the extended post-trial follow up period.
July 3, 2013
Older women who quit smoking can cut heart disease risk regardless of diabetes status
A new analysis of data from the NHLBI-supported Women's Health Initiative found that postmenopausal women who quit smoking reduced their risk of heart disease, regardless of whether they had diabetes.
March 6, 2012
Tissue factor pathway inhibitor, activated protein C resistance, and risk of ischemic stroke due to postmenopausal hormone therapy
coauthored by Jacques Rossouw, MB.ChB., F.C.P. (S.A.), M.D., Division of Cardiovascular Sciences
We report the first prospective study of the associations of acquired APC resistance and of TFPI levels with stroke, and we examine whether PHT-induced changes in these factors are associated with stroke risk in the WHI trials. We also examine associations with major subgroups of stroke.
February 15, 2010
WHI Study Data Confirm Short-Term Heart Disease Risks of Combination Hormone Therapy for Postmenopausal Women
New analyses from the Women's Health Initiative (WHI) confirm that combination hormone therapy increases the risk of heart disease in healthy postmenopausal women.
March 11, 2009
Aspirin Improves Survival in Women with Stable Heart Disease, According to WHI Study
New results from the Women's Health Initiative (WHI) Observational Study provide additional evidence that aspirin may reduce the risk of death in postmenopausal women who have heart disease or who have had a stroke.
October 9, 2007
Media Availability: Low-Fat Dietary Pattern May Lower Risk of Ovarian Cancer -- The WHI Dietary Modification Trial
A diet low in fat could reduce the risk of ovarian cancer in healthy postmenopausal women, according to new results from the Women's Health Initiative (WHI) Dietary Modification Trial.
June 20, 2007
WHI Study of Younger Postmenopausal Women Links Estrogen Therapy to Less Plaque in Arteries
New results from a substudy of the Women's Health Initiative (WHI) Estrogen-Alone Trial show that younger postmenopausal women who take estrogen-alone hormone therapy have significantly less buildup of calcium plaque in their arteries compared to their peers who did not take hormone therapy. The findings do not alter the current recommendations regarding hormone therapy use for postmenopausal women.
April 3, 2007
NHLBI Media Availability: Effect of Hormone Therapy on Risk of Heart Disease May Vary by Age and Years Since Menopause
Secondary analyses of findings from the Women's Health Initiative (WHI) suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause.
January 29, 2007
MEDIA AVAILABILITY: NHLBI Awards 12 Women's Health Initiative Contracts to Study Genetic and Biological Markers of Common Diseases Affecting Postmenopausal Women
The Women's Health Initiative (WHI) embarks on its next phase of research with 12 new contracts awarded last week by the National Heart, Lung, and Blood Institute of the National Institutes of Health. The studies will help explain the postmenopausal hormone therapy and other clinical trial findings and will investigate the impact of genetic and biological markers on common diseases affecting postmenopausal women.
April 11, 2006
WHI Updated Analysis: No Increased Risk of Breast Cancer with Estrogen-Alone
Estrogen-alone hormone therapy does not increase the risk of breast cancer in postmenopausal women, according to an updated analysis of the breast cancer findings of the Women's Health Initiative (WHI) Estrogen-Alone Trial.
February 22, 2006
Scientists and Study Participants Gather at Conference on Scientific Contributions of the Women's Health Initiative - The Largest Study of Older Women's Health
Many of the nation's leading scientists and experts on women's health will join Women's Health Initiative (WHI) study participants February 28 - March 1, 2006 at the National Institutes of Health (NIH) campus in Bethesda, MD to celebrate the legacy and probe the findings and future directions of the WHI.
February 15, 2006
WHI Study Results: Calcium & Vitamin D Supplements Offer Modest Bone Improvements, No Benefits for Colorectal Cancer
Calcium and vitamin D supplements in healthy postmenopausal women provide a modest benefit in preserving bone mass and prevent hip fractures in certain groups including older women but do not prevent other types of fractures or colorectal cancer, according to the results of a major clinical trial, part of the Women's Health Initiative (WHI).
February 7, 2006
News from the Women's Health Initiative: Reducing Total Fat Intake May Have Small Effect on Risk of Breast Cancer, No Effect on Risk of Colorectal Cancer, Heart Disease, or Stroke
Following an eating pattern lower in total fat did not significantly reduce the incidence of breast cancer, heart disease, or stroke, and did not reduce the risk of colorectal cancer in healthy postmenopausal women, according to the latest clinical trial results from the National Institutes of Health's Women's Health Initiative (WHI).
January 3, 2006
Media Availability: Low-Fat Dietary Pattern & Weight Change - the WHI Dietary Modification Trial
Results of the first study on the long-term effects of a dietary pattern low in fat and high in carbohydrates suggest that a low-fat eating pattern does not lead to weight gain.
April 13, 2004
WHI Study Finds No Heart Disease Benefit, Increased Stroke Risk With Estrogen Alone
A large, multi-center heart disease prevention study, part of the Women's Health Initiative (WHI), found that estrogen-alone hormone therapy had no effect on coronary heart disease risk but increased the risk of stroke for postmenopausal women. The study also found that estrogen-alone therapy significantly increased the risk of deep vein thrombosis, had no significant effect on the risk of breast or colorectal cancer, and reduced the risk of hip and other fractures.
November 19, 2002
Study of Menopausal Women with Heart Disease Finds No Benefit, Potential for Harm from Hormone Therapy and Antioxidant Vitamins
A study sponsored by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health found that postmenopausal women with heart disease who took hormone therapy and high dose antioxidant vitamins - either alone or in combination with hormones - did not have fewer heart attacks, deaths, or progression of coronary disease.
July 9, 2002
NHLBI Stops Trial of Estrogen Plus Progestin Due to Increased Breast Cancer Risk, Lack of Overall Benefit
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) has stopped early a major clinical trial of the risks and benefits of combined estrogen and progestin in healthy menopausal women due to an increased risk of invasive breast cancer
August 18, 1998
The HERS Study Results and Ongoing Studies of Women and Heart Disease
The results of the first large randomized clinical trial to examine the effect of hormone replacement therapy (HRT) on women with heart disease appear in the August 19 issue of the Journal of the American Medical Association (JAMA).