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Jonathan R. Kaltman, M.D.

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Portrait of Jonathan Kaltman
Jonathan R. Kaltman, M.D.


Jonathan R. Kaltman, M.D., is chief of the Heart Development and Structural Diseases Branch in the Division of Cardiovascular Sciences at the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Dr. Kaltman joined the NHLBI in 2008.

In this role, Dr. Kaltman is responsible for developing new research initiatives and managing basic and clinical research grants in the areas of pediatric cardiology, congenital cardiac genomics, sudden cardiac death, muscular dystrophy, and other pediatric cardiology-related disease states.

Dr. Kaltman provides leadership for the Pediatric Cardiac Genomics Consortium, a multi-center translational research group investigating the association of genetic variation with congenital heart disease diagnosis and outcome. He also helps oversee the Pediatric Heart Network, a multi-center clinical research network conducting studies in children with congenital heart disease.

Prior to joining the NHLBI, Dr. Kaltman served as an assistant professor at the Children’s Hospital of Philadelphia at the University of Pennsylvania School of Medicine. He then joined the Children’s National Medical Center in the District of Columbia as an assistant clinical professor. Dr. Kaltman still holds a part-time position at the Children’s National Medical Center, where his responsibilities include: outpatient pediatric cardiology/electrophysiology care, participation in catheter ablation procedures, electrophysiology consults, and education of residents and fellows.

Dr. Kaltman received his Bachelor of Science in molecular biophysics and biochemistry from Yale University, New Haven, Conn., and earned his Doctor of Medicine from Emory University School of Medicine, Atlanta.

Dr. Kaltman is a member of the Heart Rhythm Society and the American Heart Association. He also serves as a reviewer for the American Journal of Cardiology, Circulation, Heart Rhythm, and Pacing and Clinical Electrophysiology.

Areas of expertise: pediatric cardiology and electrophysiology, congenital cardiac genomics, and sudden cardiac death.

Photo courtesy of the Children’s National Medical Center.

Dr. Kaltman In the News

September 3, 2014 : Medical Expresss
Study links sex hormones in the blood to risk of sudden cardiac arrest
A new study partially funded by the National Heart, Lung, and Blood Institute and published online by the peer-reviewed journal Heart Rhythm, shows that lower levels of testosterone, the predominant male sex hormone, were found in men who had a sudden cardiac arrest. Higher levels of estradiol, the major female sex hormone, were strongly associated with greater chances of having a sudden cardiac arrest in both men and women.

August 11, 2014 : Indiana University School of Medicine
Newly discovered heart molecule could lead to effective treatment for heart failure
Researchers at the Indiana University School of Medicine have discovered a previously unknown cardiac molecule that could provide a key to treating, and preventing, heart failure. The work was partially funded by the National Heart, Lung, and Blood Institute.

View all Dr. Kaltman in the news articles

Last Updated: April 20, 2012