NHLBI-supported study finds that among young children with histories of recurrent severe lower respiratory tract illnesses (RTI), the use of azithromycin early during an apparent RTI compared with placebo reduced the likelihood of severe lower respiratory tract illnesses.
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A federally funded analysis of MRI scans of the aging hearts of nearly 3,000 adults shows significant differences in the way male and female hearts change over time. Results of the research, led by investigators at Johns Hopkins with funding from NHLBI, do not explain exactly what causes the sex-based differences but they may shed light on different forms of heart failure seen in men and women that may require the development of gender-specific treatments, the scientists say.
This unique mobile health platform would enable researchers to study a broad range of conditions to evaluate the effectiveness of new health sensors and apps. NHLBI is one of several NIH institutes supporting this effort.
A new study suggests severity of the skin condition psoriasis is associated with increased inflammation of the blood vessels, or vasculitis. Senior author Dr. Nehal N. Mehta, a Lasker clinical investigator at the National Heart, Lung, and Blood Institute, of the National Institutes of Health, and colleagues published their findings in the journal Arteriosclerosis, Thrombosis and Vascular Biology.
The National Heart, Lung, and Blood Institute (NHLBI) has awarded approximately $40 million to the Broad Institute of MIT and Harvard to provide large-scale whole genome sequencing of 20,000 individuals, as well as data to support smaller pilots in transcriptome sequencing and metabolite profiling. This project is part of NHLBI's Trans-Omics for Precision Medicine (TOPMed) program.
Prognosis and treatment for aplastic anemia require tailoring based on which mutations patients have among a handful of leukemia-related genes, according to a new study from researchers including NHLBI's Dr. Neal S. Young.
NHLBI's Dr. Toren Finkel joined a live radio panel discussion on the Diane Rehm Show to discuss his anti-aging research involving work on mice. Other panel members included National Institute on Aging's Dr. Mark Mattson and Massachusetts Institute of Technology's Leonard Guarente.
Dr. Gary H. Gibbons, director of the NHLBI, and Dr. George Mensah, director of NHLBI’s Center for Translational Research and Implementation Science, co-authoed a study published in the Journal of the American Heart Association. The study examined the factors existing at the state level that may influence cardiovascular health outcomes.
NHLBI Director Dr. Gary H. Gibbons recently spoke to medical reporters about the future of individualized medicine and highlighted the role the National Institutes of Health is poised to play in moving this field forward.
The National Academy of Sciences announced today the election of 84 new members and 21 foreign associates from 15 countries in recognition of their distinguished and continuing achievements in original research, including NHLBI's Warren J. Leonard, M.D., chief of the Laboratory of Molecular Immunology and director of the Immunology Center.