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NHLBI Symposium on Cardiovascular Regenerative Medicine

NHLBI Symposium on Cardiovascular Regenerative Medicine, September 25-26, 2013


Final Agenda

Wednesday, September 25, 2013

7:00 a.m.        Registration          

8:00 a.m.         Welcome and Opening Remarks 
                        Manfred Boehm, M.D.

                        National Heart, Lung, and Blood Institute

8:05 a.m.         Report of the NHLBI Director
                        Gary H. Gibbons, M.D.
                        National Heart, Lung, and Blood Institute

8:30 a.m.        Session I: General Stem Cells
Jonathan A. Epstein, M.D., Ph.D.
                        Perelman School of Medicine, University of Pennsylvania 
8:35 a.m.         ES Cells, iPS Cells and Disease Modeling: Technical Challenges
                        Rudolph Jaenisch, M.D.
                        Whitehead Institute and Massachusetts Institute of Technology

8:55 a.m.         Insights Into Reprogramming to Pluripotency
                        Kathrin Plath, Ph.D.
                        University of California, Los Angeles
9:15 a.m.         Milestones and Barriers in Hematopoietic Stem Cell Derivation from Pluripotent Stem Cells
                        George Q. Daley, M.D., Ph.D.

                        Children’s Hospital Boston and Harvard Medical School

9:35 a.m.         Questions & Answers

9:55 a.m.         Break
10:15 a.m.      Session II: Cardiovascular Stem Cells
John P. Cooke, M.D., Ph.D.
                        Houston Methodist Research Institute
10:20 a.m.       Reprogramming Approaches to Cardiovascular Disease
                        Deepak Srivastava, M.D.
Gladstone Institute of Cardiovascular Disease and University of California, San Francisco 

10:40 a.m.       Molecular Mechanism of Cardiac Progenitor Cell Commitment and Multi-lineage Differentiation
                        Sean M. Wu, M.D., Ph.D.
                        Stanford University School of Medicine

11:00 a.m.       Regenerating the Heart of a Non-Human Primate
                        Charles E. Murry, Ph.D., M.D.
              University of Washington

11:20 a.m.       Cardiac iPSCs for Disease Modeling and Drug Screening
                        Joseph C. Wu, M.D., Ph.D.
                        Stanford University School of Medicine

11:40 a.m.       microRNA Screening and Systems Biology To Discover Drug Targets and RNA Therapeutics for Heart Failure
                        Mark Mercola, Ph.D.
                        Sanford Burnham Medical Research Institute/University of California, San Diego

12:00 p.m.      Questions & Answers

12:20 p.m.       Lunch (on your own)

1:00 p.m.        Session III: Tissue Engineering
Amy Wagers, Ph.D.
                        Joslin Diabetes Center / Harvard University

1:05 p.m.         Forces, Form, and Regenerating Function
                        Christopher S. Chen, M.D., Ph.D.
               Boston University and Wyss Institute for Biologically Inspired Engineering, Harvard University 

1:25 p.m.         Acellular Arterial Conduits
                        Laura E. Niklason, M.D., Ph.D.
              Yale University School of Engineering and Applied Sciences 

1:45 p.m.         Questions & Answers

2:05 p.m.         Session IV: NIH Support for Stem Cell Research
Robert D. Simari, M.D.
                         Mayo Clinic

2:10 p.m.          NIH Intramural Perspective
                         Mahendra S. Rao, M.D., Ph.D.
                         NIH Center for Regenerative Medicine

2:25 p.m.          An Update from Outer Space:  The Next Generation Genetic Association Study 
                         Cashell Jaquish, Ph.D.
                         NHLBI Division of Cardiovascular Sciences

2:40 p.m.          NHLBI Progenitor Cell Biology Consortium
                         Denis B. Buxton, Ph.D.
                         NHLBI Division of Cardiovascular Sciences

2:55 p.m.          The NHLBI Lung Repair and Regeneration Consortium            
                         Carol Blaisdell, Ph.D.
                         NHLBI Division of Lung Diseases

3:10 p.m.          Questions and Answers

3:30 p.m.          Poster Session

Thursday, September 26, 2013

7:00 a.m.        Registration

8:00 a.m.       
Remembering Dr. Sonia Skarlatos  
                       Robert D. Simari, M.D.

                       Mayo Clinic and Chair, NHLBI Cardiovascular Cell Therapy Research Network

8:10 a.m.        Update on the Use of Human Adult Stem Cells in the Treatment of Cardiovascular Disease
                       James T. Willerson, M.D.
                       Texas Heart Institute               

8:30 a.m.        Session V: Clinical Applications
Jason C. Kovacic, M.D., Ph.D.
                        Mt. Sinai School of Medicine

8:35 a.m.         Stem Cell Therapy for Peripheral Arterial Disease:  Limping Along or on PACE?
                        John P. Cooke, M.D., Ph.D.

                        Houston Methodist Research Institute

8:55 a.m.         Future Directions of the NHLBI-sponsored CCTRN
                        Robert D. Simari, M.D.
                        Mayo Clinic

9:15 a.m          Use of Cardiac Stem Cells for the Treatment of Ischemic Cardiomyopathy: The SCIPIO Trial
                        Roberto Bolli, M.D.
 University of Louisville

9:35 a.m.         New Approaches to Cell Products for Cardiac Cell-based Therapy
                        Joshua M. Hare, M.D.
University of Miami Miller School of Medicine

9:55 a.m.         Questions & Answers

10:15 a.m.       Break
10:45 a.m.      Session VI: Developmental Biology
Sean M. Wu, M.D., Ph.D.
                        Stanford University School of Medicine      

10:50 a.m.       Epigenetic Regulation of Cardiac Differentiation
                        Benoit G. Bruneau, Ph.D.
               Gladstone Institute of Cardiovascular Disease / University of California, San Francisco 

11:10 a.m.       Regulation of Cardiac Progenitor Cell Expansion
                        Jonathan A. Epstein, M.D.
University of Pennsylviania Perelman College of Medicine          

11:30 a.m.       Strategies to Reverse Age-related Dysfunction in the Skeletal Muscle and Cardiovascular System
                        Amy Wagers, Ph.D.
                        Harvard University/Joslin Diabetes Center

11:50 a.m.       Guidance of Vascular Patterning
                        Anne Eichmann, Ph.D., M.Sc.
 Yale University School of Medicine          

12:10 p.m.       New Cardiomyocytes: From Progenitors, or Existing Cardiomyocytes?
                        Richard T. Lee, M.D.
                        Harvard Medical School and Brigham and Women’s Hospital

12:30 p.m.       Questions & Answers

12:50 p.m.       Lunch (on your own)                

1:30 p.m.        Session VII: Proteomics/Metabolomics
George Q.Daley, M.D., Ph.D.
                        Children's Hospital Boston / Harvard Medical School            

1:35 p.m.         A Self-Sustaining Feedback Loop That Regulates Proteome Diversity and Supports Self-renewal  
                           in Pluripotent Stem Cells
                        Jarrod A. Marto, Ph.D.
              Dana-Farber Cancer Institute/Harvard Medical School

1:55 p.m.         New Biological Insights Through Human iPS Cell-derived Hepatocytes
                        Daniel J. Rader, M.D.
University of Pennsylvania Perelman College of Medicine 

2:15 p.m.         Proteomics and Defining Stem Cells: It Matters Where You Came From
                        Jennifer Van Eyk, Ph.D.
Johns Hopkins School of Medicine

2:35 p.m.         Questions & Answers

3:00 p.m.         Closing Remarks
                        Manfred Boehm, M.D.
                        National Heart, Lung, and Blood Institute

3:15 p.m.         Adjournment

last updated 9/24/13