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NHLBI Symposium on Cardiovascular Regenerative Medicine

Agenda

Preliminary Agenda

Wednesday, September 25, 2013

7:00 a.m.        Registration          

8:00 a.m.         Welcome and Opening Remarks 
                        Manfred Boehm, M.D.
                        National Heart, Lung, and Blood Institute

8:05 a.m.         Gary H. Gibbons, M.D.
                        National Heart, Lung, and Blood Institute


8:30 a.m.        Session I: General Stem Cells
                        Moderator:  Jonathan A. Epstein, M.D., Ph.D.
                        Perelman School of Medicine, University of Pennsylvania 
         
8:35 a.m.         Milestones and Barriers in Hematopoietic Stem Cell Derivation from Pluripotent Stem Cells
                        George Q. Daley, M.D., Ph.D.
                        Children’s Hospital Boston and Harvard Medical School
         
8:55 a.m.         Insights Into Reprogramming to Pluripotency
                        Kathrin Plath, Ph.D.
                        University of California, Los Angeles
          
9:15 a.m.         ES Cells, iPS Cells and Disease Modeling: Technical Challenges
                        Rudolph Jaenisch, M.D.
                        Whitehead Institute / Massachusetts Institute of Technology

9:35 a.m.         Questions & Answers

9:55 a.m.         Break

               
10:15 a.m.      Session II: Cardiovascular Stem Cells
                        Moderator:  John P. Cooke, M.D., Ph.D.
                        Stanford University School of Medicine
          
10:20 a.m.       Reprogramming Approaches to Cardiovascular Disease
                        Deepak Srivastava, M.D.
                        Gladstone Institute of Cardiovascular Disease and University of California, San Francisco 

10:40 a.m.       Molecular Mechanism of Cardiac Progenitor Cell Commitment and Multi-lineage Differentiation
                        Sean M. Wu, M.D., Ph.D.
                        Stanford University School of Medicine

11:00 a.m.       Regenerating the Heart of a Non-Human Primate
                        Charles E. Murry, Ph.D., M.D.
                        University of Washington

11:20 a.m.       Cardiac iPSCs for Disease Modeling and Drug Screening
                        Joseph C. Wu, M.D., Ph.D.
                        Stanford University School of Medicine

11:40 a.m.       Questions & Answers

12:00 p.m.       Lunch (on your own)


1:00 p.m.        Session III: Tissue Engineering
                        Moderator:  Amy Wagers, Ph.D.
                        Joslin Diabetes Center / Harvard University

1:05 p.m.         Forces, Form, and Regenerating Function
                        Christopher S. Chen, M.D., Ph.D.
                        University of Pennsylvania School of Engineering and Applied Science  

1:25 p.m.         New Cardiomyocytes: From Progenitors, or Existing Cardiomyocytes?
                        Richard T. Lee, M.D.
                        Harvard Medical School and Brigham and Women’s Hospital

1:45 p.m.         Acellular Arterial Conduits
                        Laura E. Niklason, M.D., Ph.D.
                        Yale University School of Engineering and Applied Sciences 

2:05 p.m.         Questions & Answers

2:25 p.m.         Session IV: NIH Support for Stem Cell Research
                         Moderator:  Robert D. Simari, M.D.
                         Mayo Clinic

3:30 p.m.          Questions and Answers

4:00 p.m.          Poster Session

Thursday, September 26, 2013

7:30 a.m.        Registration

8:30 a.m.        Session V:  Clinical Applications
                        Moderator:  Jason C. Kovacic, M.D., Ph.D.
                        Mt. Sinai School of Medicine

8:35 a.m.         Stem Cell Therapy for Peripheral Arterial Disease:  Limping Along or on PACE?
                        John P. Cooke, M.D., Ph.D.
                        Stanford Cardiovascular Institute / Stanford University School of Medicine

8:55 a.m.         Future Directions of the NHLBI-sponsored CCTRN
                        Robert D. Simari, M.D.
                        Mayo Clinic

9:15 a.m          Use of Cardiac Stem Cells for the Treatment of Ischemic Cardiomyopathy: The SCIPIO Trial
                        Roberto Bolli, M.D.
                        University of Louisville

9:35 a.m.         New Approaches to Cell Products for Cardiac Cell-based Therapy
                        Joshua M. Hare, M.D.
                        University of Miami Miller School of Medicine

9:55 a.m.         Questions & Answers

10:15 a.m.       Break
       


10:45 a.m.      Session VI:  Developmental Biology
                        Moderator:  Sean M. Wu, M.D., Ph.D.
                        Stanford University School of Medicine      

10:50 a.m.       Epigenetic Regulation of Cardiac Differentiation
                        Benoit G. Bruneau, Ph.D.
                        Gladstone Institute of Cardiovascular Disease / University of California, San Francisco 

11:10 a.m.       Regulation of Cardiac Progenitor Cell Expansion
                        Jonathan A. Epstein, M.D.
                        University of Pennsylviania Perelman College of Medicine          

11:30 a.m.       Strategies to Reverse Age-related Dysfunction in the Cardiovascular System
                        Amy Wagers, Ph.D.
                        Harvard University/Joslin Diabetes Center

11:50 a.m.       Guidance of Vascular Patterning
                        Anne Eichmann, Ph.D., M.Sc.
                        Yale University School of Medicine          

12:10 p.m.       Questions & Answers

12:30 p.m.       Lunch (on your own)                

1:30 p.m.        Session VII: Proteomics/Metabolomics
                        Moderator:  George Q.Daley, M.D., Ph.D.
                        Children's Hospital Boston / Harvard Medical School            

1:35 p.m.         A Self-Sustaining Feedback Loop That Regulates Proteome Diversity and Supports Self-renewal  
                           in Pluripotent Stem Cells
                        Jarrod A. Marto, Ph.D.
                        Dana-Farber Cancer Institute/Harvard Medical School

1:55 p.m.         microRNA Screening and Systems Biology To Discover Drug Targets and RNA Therapeutics for Heart Failure
                        Mark Mercola, Ph.D.
                        Sanford Burnham Medical Research Institute/University of California, San Diego

2:15 p.m.         New Biological Insights Through Human iPS Cell-derived Hepatocytes
                        Daniel J. Rader, M.D.
                        University of Pennsylvania Perelman College of Medicine 

2:35 p.m.         Assessing Stem and Progenitor Cell Utility: The Proteomics of the Cell-environment Interface
                        Jennifer Van Eyk, Ph.D.
                        Johns Hopkins School of Medicine

2:55 p.m.         Questions & Answers

3:15 p.m.         Closing Remarks
                        Manfred Boehm, M.D.
                        National Heart, Lung, and Blood Institute

3:30 p.m.         Adjournment