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September 12, 2014
NIH awards aim to improve understanding of cell pathways, development of new therapies
Building on a successful three-year pilot project, the National Institutes of Health has awarded more than $64 million to six research institutions to create a database of human cellular responses, the Library of Integrated Network-based Cellular Signatures (LINCS).  Discovering such cell responses will improve scientists’ understanding of cell pathways and aid in the development of new therapies for many diseases.

September 9, 2014
NIH-convened panel recommends expanded adoption of drug and transfusion treatments for individuals with sickle cell disease
An expert panel has recommended expanded adoption of the drug hydroxyurea for the care of people with sickle cell disease, according to a report issued today. The report also suggests that clinicians give periodic blood transfusions to children with the disease to reduce stroke risk. According to the panel, both treatments are underutilized.

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Spotlight On Research

Featured Fact Sheet

images of the reduction in blood flow after a mental stress test compared to after a physical stress test and at rest

Emotional stress and heart disease in women: an interview with Dr. Viola Vaccarino
When it comes to the effects of emotional stress on the heart, young men and women may not be created equal. Understanding the role of emotional factors—in particular psychological stress—on heart disease risk is a professional passion for longtime NHLBI grantee, Dr. Viola Vaccarino, a leader in women’s health research. Read full fact sheet...

NHLBI In The News rss feed

September 15, 2014 : Princeton Alumni Weekly
Directing a landmark study of heart disease, Herman Taylor Jr. ’76 took on more than medicine
Katherine Hobson
Dr. Herman Taylor Jr., Director of the NHLBI-funded Jackson Heart Study is featured in Princeton Alumni Weekly (PAW). Dr. Taylor became the Director and Endowed Professor of the Cardiovascular Research Institute (CVRI) of the Morehouse School of Medicine in July. In his new position, Dr. Taylor wants to take approaches drawn from the heart study and other research and see if he can help improve outcomes. He plans to explore new ways to help people change their habits, with possibilities including using digital technology such as mobile phones to disseminate information in accessible ways.

September 10, 2014 : University of Illinois at Chicago News Center
Researchers find new targets for treating pulmonary hypertension
Sharon Parmet
Two new potential therapeutic targets for the treatment of pulmonary arterial hypertension, a deadly disease marked by high blood pressure in the lungs, have been identified by researchers at the University of Illinois at Chicago. Their findings are reported in the American Journal of Respiratory and Critical Care Medicine. This research was supported by the NHLBI.

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Upcoming Events

September 22, 2014 - September 22, 2014
NHLBI Regional Innovation Conference
Research Triangle Park, NC

NHLBI’s Office of Translational Alliances and Coordination (OTAC) hosts this semi-annual Regional Innovation Conference that brings together small businesses, angel investors, venture capitalists, strategic partners, and business leaders from the biotech, medical device, and pharmaceutical industries. NHLBI staff will be available to describe the details and impact of recent changes in the Federal SBIR/STTR program, as well as other funding opportunities and resources for small businesses.

Director's Message
Researcher Brings Medicine One Step Closer to Widely Available Cure for Sickle Cell Disease

Gary H. Gibbons
September 2, 2014

From the use of antibiotics to prevent and treat infections in children with sickle cell disease to the FDA approval of the drug hydroxyurea, researchers have made steady progress during the last few decades in improving the lives of individuals with sickle cell disease. Yet still, a widely available cure has remained just out of reach. Now, work from a team of researchers at the National Institutes of Health, including NHLBI’s Dr. John Tisdale may open the door to reversing sickle cell disease in more patients....
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