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NHLBI WORKSHOP on Women and
Ischemia Syndrome Evaluation (WISE): Diagnosis and Pathophysiology of
Ischemic Heart Disease
October 2-4, 2002 Marriott Inn
Baltimore Washington International Airport |
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[ WISE Home ] [
Agenda ] [ Participants ] [
NHLBI Home ]
AGENDA
Wednesday October 2, 2002
| Wed 10/2/02 |
Topic |
Presenter(s) |
| 8:00 am - 8:40 am |
General Session: |
| |
| 8:00 am - 8:05 am |
Welcome |
Dr. Claude Lenfant |
| 8:05 am - 8:15 am |
Charge to the Group |
Dr. George Sopko |
| 8:15 am - 8:20 am |
Introduction by Chairs |
Drs. Noel Bairey Merz & Robert Bonow |
| 8:20 am - 8:40 am |
Overview of the Field:
Status & Challenges
(pdf,
148kb) |
Dr. Noel Bairey Merz |
| |
| 8:40 am - 12:10 pm |
Session 1: Diagnosis of Stable Ischemia and CHD
Moderator: Dr. Carl Pepine
Co-Moderator: Dr. Robert Balaban |
| |
| 8:50 am - 9:10 am |
Overview (pdf,
76kb) |
Dr. Carl Pepine |
| 9:10 am - 10:10 am |
Symptoms Recognition: |
|
| |
Clinical Dx of Angina-Epidemiologic
Issue
(pdf,
192kb) |
Dr. George Diamond |
| |
Clinical Dx of Angina: WISE
Experience
(pdf,
124kb) |
Dr. B. Delia Johnson |
| |
Critical Pathway for Dx
of Ischemia (pdf,
88kb) |
Dr. Paula Johnson |
| |
| 10:10 am - 10:20 am |
Break |
| |
| 10:20 am -10:40 am |
Imaging Tests: Previous, Present
and
Future Reference Standards (pdf,
115kb) |
Drs. Gerald Pohost & Robert Balaban |
| 10:40 am - 11:00 am |
Morphologic Techniques: Angio/IVUS
(pdf,
73kb) |
Dr. Steven Nissen |
| |
Physiologic Techniques: Flow
& Endothelium
(pdf,
81kb) |
Dr. Carl Pepine |
| 11:00 am - 11:10 am |
Office-based Screening: Role
of New
Technologies for Subclinical Atherosclerosis
(pdf,
52kb)
|
Dr. Lori Mosca |
| 11:10 am -12:10 pm |
Discussion and Recommendations |
Panel |
| |
| 12:10 pm - 1:00 pm |
Working Lunch |
| |
| 1:00 pm - 3:00 pm |
Session 2: Stable Ischemia: Pathophysiology and Gender
Differences
Moderator: Dr. Rita Redberg
Co-Moderator: Dr. Richard Cannon |
| |
|
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| 1:00 pm - 1:10 pm |
Gender Issues in IHD
(pdf,
98kb) |
Dr. Noel Bairey Merz |
| 1:10 pm - 1:25 pm |
Macrovascular vs. Microvascular
Disease
(pdf,
153kb) |
Dr. Steven Reis |
| 1:25 pm - 1:40 pm |
Endothelial Dysfunction and
Ischemia
(pdf,
110kb) |
Dr. Amir Lerman |
| 1:40 pm - 1:50 pm |
Pain Threshold & Perception
(pdf,
170kb) |
Dr. David Sheps |
| 1:50 pm - 2:00 pm |
Visceral Sensitivity and Chest
Pain (pdf,
76kb) |
Dr. Richard Cannon |
| 2:00 pm - 3:00 pm |
Discussion and Recommendations |
Panel |
| |
| 3:00 pm - 3:10 pm |
Break |
| |
| 3:10 pm - 5:00 pm |
Session 3: Diagnosis of Acute Cardiac Ischemia: Gender
Issues
Moderator: Drs. Elizabeth Nabel and Harry Selker
Co-Moderator: Dr. Patrice Desvigne-Nickens |
| |
| 3:10 pm - 3:20 pm |
Pathology of Acute Ischemic
Syndrome
(pdf,
81kb) |
Dr. Renu Virmani |
| 3:20 pm - 3:55 pm |
Experience From Large Data
Bases:
Are There Gender Differences (National
Registry of MI; MITI, other) (pdf,
kb) |
Drs. John Canto, Jane Cao,
Viola Vaccarino & Rob Califf |
| 3:55 pm - 4:15 pm |
Presentation in ED (pdf,
92kb) |
Dr. Harry Selker |
| 4:15 pm - 4:30 pm |
REACT Study Experience
(pdf,
66kb) |
Drs. Robert Goldberg & John Finnegan |
| 4:30 pm - 5:30 pm |
Discussion and Recommendations |
Panel |
| |
| 5:30 pm - 6:30 pm |
Working Dinner |
| |
| 6:30 pm - 8:00 pm |
Session 4: Lessons from Hormone Replacement Trials (HRT)
Moderator: Dr. David Waters
Co-Moderators: Drs. David Gordon and Jacques Rossouw |
| |
| General |
| |
| 6:30 pm - 6:50 pm |
HRT: Impact on Ischemia Pathophysiology
(pdf,
77kb) |
Drs. Peter Collins & Richard Cannon |
| 6:50 pm - 7:05 pm |
HRT In Acute Coronary Syndromes
(pdf,
66kb) |
Dr. Pam Ouyang |
| 7:05 pm - 7:20 pm |
HRT in Secondary Prevention
(HERS&ERA)
(pdf,
81kb) |
Drs. David Herrington & David Waters |
| 7:20 pm - 7:35 pm |
SERMS Impact on Ischemic Pathophysiology
(pdf,
63kb) |
Dr. Lori Mosca |
| |
| Women Health Initiative Study (WHI) |
| |
| 7:35 pm - 7:45 pm |
WHI: Major Results of the Trial
&
Observational Study (pdf,
80kb)
|
Dr. Judy Hsia |
| 7:45 pm - 8:00 pm |
HRT and Presentation of
Ischemia:
Subgroup Analyses (pdf,
70kb) |
Dr. Marcia Stefanick |
| 8:00 pm - 8:15 pm |
WHI: Hormonal Influences:
Future Opportunities (pdf,
77kb) |
Dr. Robert Langer |
| |
| 8:50 pm - 10:30 pm |
Working Discussions |
Thursday October 3, 2002
| Thu 10/3/02 |
Topic |
Presenter(s) |
| 8:00 am - 12:00 pm |
Session 5: Gender-Related Risk Factors for IHD
Moderator: Drs. Jannet Lewis and Leslee Shaw
Co-Moderator: Dr. Teri Manolio |
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| Risk Factors |
| |
| 8:00 am - 8:10 am |
Traditional Risk Factors
(ARIC Results)
(pdf,
57kb) |
Dr. Richey Sharrett |
| 8:10 am - 8:20 am |
Diabetes and Other Metabolic
States
(pdf,
63kb) |
Dr. Willa Hsueh |
| 8:20 am - 8:30 am |
Novel Risk Factors (pdf,
106kb) |
Dr. Russell Tracy |
| 8:30 am - 8:50 am |
Discussion |
Panel |
| |
| Alterations in Microvascular Flow, Metabolism,
& Ischemia Testing |
| |
| 8:50 am - 9:00 am |
Conventional Ischemia Testing
Research Update: Echo, SPECT, ECG
(pdf,
259kb)
|
Dr. Leslee Shaw |
| 9:00 am - 9:10 am |
Limitations of Conventional
Testing and
Innovative Imaging Techniques
Focus on Results from WISE (pdf,
78kb)
|
Dr. Sheryl Kelsey |
| 9:10 am - 9:20 am |
Funduscopy vs. Gender CAD Risk
(pdf,
65kb) |
Dr. Ron Klein |
| 9:20 am - 9:40 am |
Discussion |
Panel |
| |
| 9:40 am - 9:50 am |
Break |
| |
| 9:50 am - 10:20 am |
Issues of Cost Effectiveness
(pdf,
54kb)
Focus on False Positive / Negative Costs
of Conventional Testing; Establishing Cost
Effectiveness of New Technology (pdf,
197kb)
|
Drs. Leslee Shaw & Mark Hlatky |
| 10:20 am -12:00 pm |
Discussion |
Panel |
| |
| 12:00 pm - 1:00 pm |
Working Lunch |
| |
| 1:00 pm - 4:00 pm |
Session 6: Key Messages About Symptoms of Acute IHD in
Women and
Recommendations for Practice
Moderator: Dr. Sharonne Hayes
Co-Moderators: Ms. Terry Long and Mary Hand |
| |
| 1:00 pm - 1:40 pm |
Creating a Science-Based Public
Education Message on Heart Attack
Recognition and Response (pdf,
158 kb)
|
Ms. Mary Hand
Ms. Terry Long |
| 1:40 pm - 2:00 pm |
What Do Health Care Providers
Need to Know About Heart Disease
Presentations in Women (pdf,
89kb) |
Dr. Harry Selker |
| 2:00 pm -2:30 pm |
What Messages Should Be Communicated
to
Patients and the Public About Heart Attack
Symptoms in Women (pdf,
80kb) |
Dr. John Finnegan |
| 2:30 pm - 4:00 pm |
Discussion |
Panel |
| |
| 4:00 pm - 4:10 pm |
Break |
| |
| 4:10 pm - 6:30 pm |
Session 7: New Frontiers In Detection of IHD in Women
Moderator: Drs. Atilio Maseri, Robert Bonow and Noel Bairey Merz
Co-Moderator: Dr. George Sopko |
| |
| 4:10 pm - 4:30 pm |
Future Clinical Research Directions:
(pdf,
110kb) |
Dr. Atilio Maseri |
| 4:30 pm - 6:30 pm |
Need for Gender-Specific Tools
(Bio-markers, Algorithms, Stratification) |
Group Discussion |
| |
Future Education Strategies:
(Public, Provider and Care Givers) |
Group Discussion |
| |
Recommendations |
Panel |
| |
| 7:30 pm - 9:30 pm |
Dinner with Working Discussions |
Friday October 4, 2002
| Fri 10/4/02 |
Topic |
Presenter(s) |
| 8:00 am - 12:00 pm |
Session 8: Individual Sessions: Overall Draft Report Generation
Moderators: Drs. Noel Bairey Merz and Robert Bonow
Co-Moderator: Dr. George Sopko |
| |
| 8:00 am - 10:00 am |
Recommendations Sessions 1-7 |
Session Moderators |
| 10:00 am - 11:00 am |
Discussion |
Panel |
| 11:00 am - 11:30 am |
Summary Statement, Next Steps |
Drs. Merz & Bonow |
| 11:30 am - 12:00 pm |
Closing Remarks: |
Drs. Sopko & Morosco |
| |
| 12:00 pm - 3:00 pm |
Session Chairs: Draft of the Workshop Proceedings |
[ WISE Home ] [
Agenda ] [ Participants ] [
NHLBI Home ]
Please send your feedback, comments, and
questions to Suzanne Goldberg at goldbergs@nhlbi.nih.gov.
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