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NHLBI WORKSHOP on
Women and Ischemia Syndrome Evaluation (WISE):
Diagnosis and Pathophysiology of Ischemic Heart Disease

October 2-4, 2002
Marriott Inn
Baltimore Washington International Airport

NW Native American owl

[ WISE Home ] [ Agenda ] [ Participants ] [ NHLBI Home ]

AGENDA

Wednesday October 2, 2002

Wed 10/2/02 Topic Presenter(s)
8:00 am - 8:40 am General Session:
 
8:00 am - 8:05 am Welcome Dr. Claude Lenfant
8:05 am - 8:15 am Charge to the Group Dr. George Sopko
8:15 am - 8:20 am Introduction by Chairs Drs. Noel Bairey Merz & Robert Bonow
8:20 am - 8:40 am Overview of the Field: Status & Challenges
(pdf, 148kb)
Dr. Noel Bairey Merz
 
8:40 am - 12:10 pm Session 1: Diagnosis of Stable Ischemia and CHD
Moderator: Dr. Carl Pepine
Co-Moderator: Dr. Robert Balaban
 
8:50 am - 9:10 am Overview (pdf, 76kb) Dr. Carl Pepine
9:10 am - 10:10 am Symptoms Recognition:  
  Clinical Dx of Angina-Epidemiologic Issue
(pdf, 192kb)
Dr. George Diamond
  Clinical Dx of Angina: WISE Experience
(pdf, 124kb)
Dr. B. Delia Johnson
  Critical Pathway for Dx of Ischemia (pdf, 88kb) Dr. Paula Johnson
 
10:10 am - 10:20 am Break
 
10:20 am -10:40 am Imaging Tests: Previous, Present and
Future Reference Standards
(pdf, 115kb)
Drs. Gerald Pohost & Robert Balaban
10:40 am - 11:00 am Morphologic Techniques: Angio/IVUS
(pdf, 73kb)
Dr. Steven Nissen
  Physiologic Techniques: Flow & Endothelium
(pdf, 81kb)
Dr. Carl Pepine
11:00 am - 11:10 am Office-based Screening: Role of New
Technologies for Subclinical Atherosclerosis

(pdf, 52kb)
Dr. Lori Mosca
11:10 am -12:10 pm Discussion and Recommendations Panel
 
12:10 pm - 1:00 pm Working Lunch
 
1:00 pm - 3:00 pm Session 2: Stable Ischemia: Pathophysiology and Gender Differences
Moderator: Dr. Rita Redberg
Co-Moderator: Dr. Richard Cannon
     
1:00 pm - 1:10 pm Gender Issues in IHD (pdf, 98kb) Dr. Noel Bairey Merz
1:10 pm - 1:25 pm Macrovascular vs. Microvascular Disease
(pdf, 153kb)
Dr. Steven Reis
1:25 pm - 1:40 pm Endothelial Dysfunction and Ischemia
(pdf, 110kb)
Dr. Amir Lerman
1:40 pm - 1:50 pm Pain Threshold & Perception (pdf, 170kb) Dr. David Sheps
1:50 pm - 2:00 pm Visceral Sensitivity and Chest Pain (pdf, 76kb) Dr. Richard Cannon
2:00 pm - 3:00 pm Discussion and Recommendations Panel
 
3:00 pm - 3:10 pm Break
 
3:10 pm - 5:00 pm Session 3: Diagnosis of Acute Cardiac Ischemia: Gender Issues
Moderator: Drs. Elizabeth Nabel and Harry Selker
Co-Moderator: Dr. Patrice Desvigne-Nickens
 
3:10 pm - 3:20 pm Pathology of Acute Ischemic Syndrome
(pdf, 81kb)
Dr. Renu Virmani
3:20 pm - 3:55 pm Experience From Large Data Bases:
Are There Gender Differences (National
Registry of MI; MITI, other)
(pdf, kb)
Drs. John Canto, Jane Cao,
Viola Vaccarino & Rob Califf
3:55 pm - 4:15 pm Presentation in ED (pdf, 92kb) Dr. Harry Selker
4:15 pm - 4:30 pm REACT Study Experience (pdf, 66kb) Drs. Robert Goldberg & John Finnegan
4:30 pm - 5:30 pm Discussion and Recommendations Panel
 
5:30 pm - 6:30 pm Working Dinner
 
6:30 pm - 8:00 pm Session 4: Lessons from Hormone Replacement Trials (HRT)
Moderator: Dr. David Waters
Co-Moderators: Drs. David Gordon and Jacques Rossouw
 
General
 
6:30 pm - 6:50 pm HRT: Impact on Ischemia Pathophysiology
(pdf, 77kb)
Drs. Peter Collins & Richard Cannon
6:50 pm - 7:05 pm HRT In Acute Coronary Syndromes
(pdf, 66kb)
Dr. Pam Ouyang
7:05 pm - 7:20 pm HRT in Secondary Prevention (HERS&ERA)
(pdf, 81kb)
Drs. David Herrington & David Waters
7:20 pm - 7:35 pm SERMS Impact on Ischemic Pathophysiology
(pdf, 63kb)
Dr. Lori Mosca
 
Women Health Initiative Study (WHI)
 
7:35 pm - 7:45 pm WHI: Major Results of the Trial &
Observational Study
(pdf, 80kb)
Dr. Judy Hsia
7:45 pm - 8:00 pm HRT and Presentation of Ischemia:
Subgroup Analyses
(pdf, 70kb)
Dr. Marcia Stefanick
8:00 pm - 8:15 pm WHI: Hormonal Influences:
Future Opportunities
(pdf, 77kb)
Dr. Robert Langer
 
8:50 pm - 10:30 pm Working Discussions

Thursday October 3, 2002

Thu 10/3/02 Topic Presenter(s)
8:00 am - 12:00 pm Session 5: Gender-Related Risk Factors for IHD
Moderator: Drs. Jannet Lewis and Leslee Shaw
Co-Moderator: Dr. Teri Manolio
 
Risk Factors
 
8:00 am - 8:10 am Traditional Risk Factors (ARIC Results)
(pdf, 57kb)
Dr. Richey Sharrett
8:10 am - 8:20 am Diabetes and Other Metabolic States
(pdf, 63kb)
Dr. Willa Hsueh
8:20 am - 8:30 am Novel Risk Factors (pdf, 106kb) Dr. Russell Tracy
8:30 am - 8:50 am Discussion Panel
 
Alterations in Microvascular Flow, Metabolism, & Ischemia Testing
 
8:50 am - 9:00 am Conventional Ischemia Testing
Research Update: Echo, SPECT, ECG

(pdf, 259kb)
Dr. Leslee Shaw
9:00 am - 9:10 am Limitations of Conventional Testing and
Innovative Imaging Techniques
Focus on Results from WISE
(pdf, 78kb)
Dr. Sheryl Kelsey
9:10 am - 9:20 am Funduscopy vs. Gender CAD Risk (pdf, 65kb) Dr. Ron Klein
9:20 am - 9:40 am Discussion Panel
 
9:40 am - 9:50 am Break
 
9:50 am - 10:20 am Issues of Cost Effectiveness (pdf, 54kb)
Focus on False Positive / Negative Costs
of Conventional Testing; Establishing Cost
Effectiveness of New Technology
(pdf, 197kb)
Drs. Leslee Shaw & Mark Hlatky
10:20 am -12:00 pm Discussion Panel
 
12:00 pm - 1:00 pm Working Lunch
 
1:00 pm - 4:00 pm Session 6: Key Messages About Symptoms of Acute IHD in Women and
Recommendations for Practice
Moderator: Dr. Sharonne Hayes
Co-Moderators: Ms. Terry Long and Mary Hand
 
1:00 pm - 1:40 pm Creating a Science-Based Public
Education Message on Heart Attack
Recognition and Response
(pdf, 158 kb)
Ms. Mary Hand
Ms. Terry Long
1:40 pm - 2:00 pm What Do Health Care Providers
Need to Know About Heart Disease
Presentations in Women
(pdf, 89kb)
Dr. Harry Selker
2:00 pm -2:30 pm What Messages Should Be Communicated to
Patients and the Public About Heart Attack
Symptoms in Women
(pdf, 80kb)
Dr. John Finnegan
2:30 pm - 4:00 pm Discussion Panel
 
4:00 pm - 4:10 pm Break
 
4:10 pm - 6:30 pm Session 7: New Frontiers In Detection of IHD in Women
Moderator: Drs. Atilio Maseri, Robert Bonow and Noel Bairey Merz
Co-Moderator: Dr. George Sopko
 
4:10 pm - 4:30 pm Future Clinical Research Directions: (pdf, 110kb) Dr. Atilio Maseri
4:30 pm - 6:30 pm Need for Gender-Specific Tools
(Bio-markers, Algorithms, Stratification)
Group Discussion
  Future Education Strategies:
(Public, Provider and Care Givers)
Group Discussion
  Recommendations Panel
 
7:30 pm - 9:30 pm Dinner with Working Discussions

Friday October 4, 2002

Fri 10/4/02 Topic Presenter(s)
8:00 am - 12:00 pm Session 8: Individual Sessions: Overall Draft Report Generation
Moderators: Drs. Noel Bairey Merz and Robert Bonow
Co-Moderator: Dr. George Sopko
 
8:00 am - 10:00 am Recommendations Sessions 1-7 Session Moderators
10:00 am - 11:00 am Discussion Panel
11:00 am - 11:30 am Summary Statement, Next Steps Drs. Merz & Bonow
11:30 am - 12:00 pm Closing Remarks: Drs. Sopko & Morosco
 
12:00 pm - 3:00 pm Session Chairs: Draft of the Workshop Proceedings

[ WISE Home ] [ Agenda ] [ Participants ] [ NHLBI Home ]

Please send your feedback, comments, and questions to Suzanne Goldberg at goldbergs@nhlbi.nih.gov.

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