NATIONAL CENTER ON SLEEP DISORDERS RESEARCH
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE

Sleep Disorders Research Advisory Board Meeting Minutes

April 14, 2009


TABLE OF CONTENTS

Attendees
Introduction
Adoption Of Minutes From The December 4, 2007 SDRAB Meeting
NCSDR Director's Report: Michael Twery, PhD
2008 Sleep Disorders Research Plan
Sleepiness and Health-Related Quality of Life
Comments and Discussion
Action Items
Next Meeting
Certification


Sleep Disorders Research Advisory Board Page


BOARD MEMBERS PRESENT

Dr. Phyllis Zee, Chair
Dr. Sonia Ancoli-Israel
Ms. Rose Austin
Dr. Charles Czeisler
Dr. F. Javier Nieto
Mr. Robert Waterman

BOARD MEMBERS ABSENT

Ms. Karen Cushing
Dr. Estelle Gauda
Dr. Howard Roffwarg

EX OFFICIO MEMBERS PRESENT

Dr. Michael Twery, NHLBI, Executive Secretary

LIAISON MEMBERS PRESENT

Dr. Merrill M. Mitler, NINDS

FEDERAL EMPLOYEES PRESENT

Mr. Peyvand Ghofrani, NHLBI, NIH
Dr. Aaron Laposky, NHLBI, NIH
Dr. Daniel Lewin, NHLBI, NIH

MEMBERS OF THE PUBLIC PRESENT

Mr. Darrel Drobnich, National Sleep Foundation
Dr. Robert Stickgold, Harvard University

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INTRODUCTION

  • Dr  Zee called the meeting to order. Dr. Twery welcomed those present.
  • Conflict of interest issues, ethics disclosure, and responsibilities associated with NIH Advisory Board membership were identified for members to review. Meeting was announced in the Federal Register on March 23, 2009.
  • Those in attendance introduced themselves.

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ADOPTION OF MINUTES FROM THE JUNE 19, 2007 SDRAB MEETING

  • Dr. Czeisler made a motion that the December 2007 meeting minutes be adopted without amendment, and Dr. Ancoli-Israel seconded the motion. The motion carried unanimously.

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NCSDR DIRECTOR'S REPORT: Michael Twery, PhD

  • Grant types and trends funded across NIH institutes having to do with sleep and circadian biology through fiscal year 2008 were presented.
  • Support for sleep research through the National Center for Research Resource CTSA program was presented. Researchers were encouraged to take advantage of the CTSA infrastructure in developing research proposals.
  • Existing and current opportunities for competitive applications were presented, including a summary of activities specific to National Center for Sleep Disorders Research.
  • An update on American Recovery and Reinvestment Act of 2009 related activities was presented.
  • Researchers were encouraged to stay informed and connected, and to continue to send in applications to the NIH.

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SLEEP DISORDERS RESEARCH PLAN

  • A process for revision of the strategic plan was presented.
  • The process will be initiated by a public Request for Information (RFI) inviting comments on potential research directions. A Board working group would draft a preliminary draft for discussion with staff representing sleep research programs NIH-wide. The Board will adopt a draft document that will be disseminated for public comment. The Board will integrate these comments and provide a final Research Plan for consideration by NIH Institutes
  • The goal is to develop an implementable strategy that broadly identifies potential roles of the NIH, and stakeholder communities.
  • Following discussion, the Board concurred with the proposed process.

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SLEEPINESS AND HEALTH-RELATED QUALITY OF LIFE

  • The board discussed the Sleepiness and Health-related Quality of Life conference April 13th and 14th that highlighted sleep research activities NIH-wide
  • A brief summary of the conference was presented by Dr. Zee.

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COMMENTS AND DISCUSSION

The board took comments and questions from the public and discussed them. The following areas of interest emerged:

  • Connecting pediatric and adult sleep research.
  • Disparities of self-reports vs. objective measures.
  • Longitudinal studies are needed to assess chronic exposures.
  • Contributions of sleep to other disorders. Examples include depression, ADHD and PTSD.
  • Studies of sleep as a primary disease risk factor are needed.
  • Intervention studies are needed to determine whether the treatment of sleep disorders improves clinically significant outcomes. For example: sleep apnea may contribute to depression; how can CPAP be used to reduce the risk of as a part of therapeutic strategy for depression? Giving sleep medications the night after trauma may reduce PTSD.
  • Sleep research is not as widespread as it should be. Sleep medicine is not being taught in universities. Physicians do not routinely ask their patients about sleep quality and problems.

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ACTION ITEMS

  • Revision of the sleep disorders strategic research plan.
  • Annual visits by National Center on Sleep Disorders Research staff with liaisons in other Federal offices and agencies.

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NEXT MEETING

These Minutes will be presented to the full Board at its next regularly scheduled meeting for consideration, amendment as approved, and formal adoption.

CERTIFICATION

I hereby certify that the foregoing minutes are accurate and complete.

Phyllis Zee, MD, PhD
Chair, Sleep Disorders Research Advisory Board

Michael Twery, PhD
Executive Secretary, Sleep Disorders Research Advisory Board

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