Agenda

Noon

Registration

1:30 - 1:45 p.m.

Welcome – Helena O. Mishoe, Ph.D., M.P.H.
Director, Office of Research Training and Minority Health
(ORTMH), National Heart, Lung, and Blood Institute (NHLBI)

Welcome and Opening Remarks
Susan Shurin, M.D., Acting Director, NHLBI

Welcome – Bert Shapiro, Ph.D.
Program Director, Medical Scientist Training Program
National Institute of General Medical Sciences, NIH

Conference Moderator – Nara Gavini, Ph.D.
ORTMH, NHLBI

1:45 - 2:30 p.m.

Session I: Career Paths and Opportunities

Issac (Zak) S. Kohane , M.D., Ph.D.

Lawerence J. Henderson Professor of Pediatrics and Health Sciences and Technology, Harvard Medical School
Boston, MA

Title: From Swiss Banks to DNA Banks: Finding the "Money" in Science.

2:30 - 3:00 p.m.

Break

3:00 - 5:00 p.m.

Session II: Funding Opportunities, Research Resources, and NIH Application and Review Process

Session Chair: Isaac (Zak) S. Kohane, M.D., Ph.D.

• Helena O. Mishoe, Ph.D., M.P.H.
  Director, ORTMH, NHLBI
  Title: Next Stage Funding Opportunities


• Dina Paltoo, Ph.D.
  Program Director, Division of Cardiovascular Sciences, NHLBI
  Title: Research Resources Available to Trainees


• Roy White, Ph.D.
  Referral Officer, Division of Extramural Research Activities, NHLBI
  Title: NIH Application and Review Process


• Herbert Geller, Ph.D.
  Director, Office of Education
  Division of Intramural Research, NHLBI
  Title: NHLBI Intramural Research Opportunities

5:00 p.m.

Opportunity for Poster set up followed by Adjournment

7:30 - 8:30 a.m.

Poster setup

8:30 - 9:30 a.m.

Scientific Keynote speaker
Cynthia E. Dunbar, M.D.

Head, Molecular Hematopoiesis Section
Principal Investigator, NHLBI, NIH

Title: Insights into Hematopoiesis and Leukemogenesis from Two Decades of Pursuing Hematopoietic Stem Cell Gene Therapy

9:30 - 11:00 a.m.

Session III: Scientific Research Presentations I

Session Chairs: Drew Carlson, Ph.D., Chitra Krishnamurti, Ph.D.

Presenters:

Cynthia N. Perry
University of California San Diego School of Medicine
Xenotransplantation of Mitochondrial Electron Transfer Enzyme, Ndi1, Treats Myocardial Reperfusion Injury

Daniel S. Herman
Harvard Medical School
Filter-Based Hybridization Capture of Subgenomes Enables Resequencing and Copy-Number Detection

Jonathan A. Waxman
University of Illinois at Chicago
Prediction of Individual Episodes of Apnea and Hypopnea Using a LAMSTAR Artificial Neural Network

Daiva M. Mattis
University of Illinois at Urbana-Champaign College of Medicine
Engineering a High Affinity T Cell Receptor Antagonist for Staphylococcal Enterotoxin C3

Sondra Maureen Nemetski
New York University School of Medicine
Structure-Based Anti-Malarial Drug Design via Enhancing Aldolase-TRAP Binding

11:00 - 11:15 a.m.

Break

11:15 - 12:15 p.m.

Session IV: Viewing Posters

12:15 - 1:15 p.m.

Lunch/viewing posters

1:30 - 2:15 p.m.

Scientific Keynote speaker
Ajay Chawla , M.D., Ph.D.

Assistant Professor, Medicine, Stanford University School of Medicine, Stanford, CA

Title: Integration of Metabolism and Inflammation by PPARs

2:15 - 3:45 p.m.

Session V: Scientific Research Presentations II

Session Chairs: Sandra Colombini Hatch, M.D., Traci Mondoro, Ph.D.

Presenters:

David W. Van Norstrand
Mayo Clinic
The Cardiac Sodium Channel Macromolecular Complex and Sudden Infant Death Syndrome

Hasina Hamilton Outtz
Columbia University Medical Center
Notch Signaling Functions in the Inflammatory Response During Wound Healing and Regulates VEGFR-1 and Cytokine Expression in Macrophages

Tyler D. Bold
New York University School of Medicine
Chronic Phase Antigen Deficit Limits the Efficacy of Adaptive Immunity to M. tuberculosis

Rebecca L. Porter
University of Rochester School of Medicine
Prostaglandin E2 Signaling in the Bone Marrow Microenvironment Protects Primitive Hematopoietic Cells from Myeloablative Injury

Danielle Shin
University of California San Francisco
Biochemical Characterization of Germline CBL Mutations Identified in Juvenile Myelomonocytic Leukemia

3:45 - 6:30 p.m.

Session VI: Poster Session and Networking

6:30 p.m.

Poster break down/Adjournment

8:00 - 8:30 a.m.

David M. Engman , M.D., Ph.D.

Professor of Pathology and MSTP Director, Feinberg School of Medicine
Northwestern University, Chicago, IL
Past President of the National Association of M.D.-Ph.D.
Program, Past Chair, AAMC M.D.-Ph.D. Section

Title: Trypanosomes and Life: My Past and Your Future as a Cardiovascular Physician-Scientist

8:30 - 10:00 a.m.

Session VII: Scientific Research Presentations III

Session Chairs: Charlotte Pratt, Ph.D., Bert Shapiro, Ph.D.

Presenters:

Scott D. Lundy
University of Washington
Mechanical and Biochemical Characteristics of Human Stem Cell-Derived Cardiomyocytes

Matthew P. Thorpe
University of Illinois at Urbana-Champaign
Preventing Weight Gain in Female Freshmen: Rationale and Baseline Participant Characteristics

Erin M. Parry
Johns Hopkins University School of Medicine
Regulatory Mutations in Dyskerin Lead to Decreased Telomerase RNA Levels and Familial Idiopathic Pulmonary Fibrosis

Andrew Chow
Mount Sinai School of Medicine
Bone Marrow Mononuclear Phagocytes Promote Retention of Hematopoietic Stem and Progenitor Cells

Anand Narayan
Johns Hopkins School of Medicine
Anticoagulation Does Not Prevent Venous Thromboembolism Following Vena Cava Filter Placement: A Retrospective Study of 702 Patients

10:00 - 10:15 a.m.

Break

10:15 - 11:15 a.m.

Session VIII: Breakout Sessions - Basic, Clinical, and Translation Research in the 21st century: Opportunities and Challenges – Trainees Talk – NHLBI Listens

Chair: Herbert Geller, Ph.D.

Breakouts:

– Basic Research – Chair: Alan Michelson, M.D., Ph.D., NHLBI
– Clinical Research – Chair: Michael Lauer, M.D., NHLBI
– Translation Research – Chair: Cynthia E. Dunbar, M.D., NHLBI

11:15 - 11:50 a.m.

Synopsis of Breakout Sessions - (Basic, Clinical, and Translation Research)

11:50 - Noon

Wrap up and Adjournment
Helena O. Mishoe, Ph.D., M.P.H.