Program

Time

Topic

Speaker

7:30 a.m.

Registration, Exhibits and Continental Breakfast

8:30 a.m.

Welcome

8:45 a.m. - 11:40 a.m.

Session I: Imaging Modalities

MRI

Axel Haase, Ph.D., University of Würzburg

MicroPET

Heinrich Schelbert, M.D., University of California Los Angeles

Ultrasound Biomicroscopy in Mouse Cardiovascular and Neural Development

Daniel Turnbull, M.D., New York University

Break

Echocardiography

Roberto Lang, M.D., University of Chicago Medical Center

3D Reconstruction of Gene Expression Patterns in Cardiac Development

Antoon Moorman, Ph.D., Academic Medical Center Amsterdam

11:40 a.m. - 12:30 p.m.

Discussion - Imaging Modalities and Mouse Cardiovascular Phenotype Analysis

Lunch and Exhibits

1:45 p.m. - 4:00 p.m.

Session II: Functional Assessments

Applications and Evaluation of Radio-Telemetry in Small Laboratory Animals

Klaas Kramer, DVM, Vrije Universiteit

High Resolution Imaging of Electrical Activity in Embryonic and Adult Mice

Gregory Morley, Ph.D., Mount Sinai School of Medicine

Electrophysical Phenotyping in Genetically Engineered Mice

Charles Berul, M.D., Harvard Medical School

Break

Analysis of the "Cardiome"

James Bassingthwaighte, M.D., Ph.D., University of Washington

4:00 p.m. - 4:30 p.m.

Discussion - The Problem of Anesthesia

4:30 p.m. - 6:30 p.m.

Reception, Poster Session, and Exhibits

6:30 p.m. - 8:30 p.m.

Tour of NIH Mouse Imaging Facility

Time

Topic

Speaker

7:30 a.m.

Continental Breakfast and Exhibits

8:30 a.m. - 11:25 a.m.

Session III: Modeling Human Cardiovascular Function and Disease

Exercise Assessment of Transgenic Models of Human Cardiovascular Disease

Daniel Bernstein, M.D., Stanford University

Atherosclerosis and Coronary Artery Disease

Monty Krieger, Ph.D. Massachusetts Institute of Technology

Cardiomyopathy

Jeffrey A. Towbin, M.D., Baylor College of Medicine

Break

Congenital Anomalies/DiGeorge Syndrome

Antonio Baldini, M.D., Baylor College of Medicine

Comparative Anatomy of the Developing Mouse and Human Heart

Andy Wessels, Ph.D.

11:25 a.m. - 12:00 noon

Discussion - Mouse vs. Other Animal Models

Lunch and Exhibits

1:30 p.m. - 3:00 p.m.

Session IV: Genomic Approaches

Molecular Identity of a Novel Head-Heart Organizer

Margaret L. Kirby, Ph.D., Duke University

Cardiogenomics: Divergent Gene Expression Profiles in Physiological and Pathophysiological Cardiac Hypertrophy

Martina Schinke, Ph.D., Beth Israel Deaconess Medical Center

Discovering Novel Pathways in Cardiovascular Development and Disease Using Mouse ENU Mutagenesis

Monica J. Justice, M.D., Baylor College of Medicine

3:00 p.m. - 3:45 p.m.

Discussion - Gene Expression Profiling and Phenotype Database

3:45 p.m.

Adjourn