| 8:30 a.m. |
Introduction and Charge |
Dr. Mockrin |
| 8:45 a.m. |
Rat History and Background |
Dr. Gill |
| 8:55 a.m. |
Rat Genome Resources |
Dr. Jacob |
| 9:15 a.m. |
Rat Nomenclature and Rat Map |
Dr. Levan |
| 9:30 a.m. |
Overview of Major Strains
- Cardiovascular/Renal
- Neurobiology/Aging/Mental Health
|
Dr. Rapp
Dr. Harris |
| 10:00 a.m. |
Break |
| 10:15 a.m. |
Overview Major Strains
- Immunology
- Cancer
- Diabetes
- Transgenesis
|
Dr. Gill
Dr. Pitot
Dr.
Guberski
Dr. Hammer |
| 11:00 a.m. |
Existing Repository Programs
- Europe
- Japan
- USA
- Commercial
Charles
River
Harlan
Sprague-Dawley
|
Dr. Hedrich
Dr. Nomura
Dr.
Rall
Dr. Balk
Dr. Russell |
| 12:30 p.m. |
Lunch |
| 1:30 p.m. |
Jax Strategies for Mouse |
Dr. Mobraaten |
| 1:50 p.m. |
New Strains - Prospects and Promise
Rat ES
Cell/Nuclear Transfer
RI
Strains
Consomics/Congenics
Transgenics/KOs/KIs |
Dr. Iannaccone
Dr. Printz
Dr.
Kwitek-Black
Dr. Hammer |
| 3:15 p.m. |
Breakout Groups |
| Group 1 |
Strain Selection
- Criteria for admission to the
repository
- Finding strains
- Criteria for animal distribution
(academic/commercial)
- Criteria and number of substrains
maintained
- Costs
|
Dr. Festing |
| Group 2 |
The Repository
- Central or distributed resource
- Academic and/or commercial distribution
- Import/export
- Existing strains
- New strains
- Requirements: spf/naf
- Quality control
- Costs
|
Dr. Cork |
| Group 3 |
Maintenance
- Cryopreserve or maintain breeding
colonies
- Research and development for maintenance
and preservation
- Identify key features for standard
protocol/back-up for storage (cryopreservation)
- Preservation of strains not selected
- Costs
|
Drs. Pakes and
Iannaccone |
| Group 4 |
Operations
- Advisory group structure, operation,
reporting
- How involved is NIH?
- Advertising/Marketing
- Cost Recovery
- Informatics - Interface with databases
- Costs
|
Dr. Hammer |
| 6:00 p.m. |
Recess |
| 6:30 p.m. |
Reception |
| 7:00 p.m. |
Dinner |
| 8:30 p.m. |
Write up Breakout Group
recommendations for handouts in the morning |
HOME
Department of Health
and Human Services
National
Institutes of Health
National Heart, Lung, and Blood
Institute