Trans–NIH Workshop

Genome-wide Association: Analyze This!
The Genes, Environment, and Health Initiative

The Natcher Conference Center
National Institutes of Health

Bethesda, Maryland
August 4–5, 2008


This workshop was held in order to share and discuss statistical strategies to identify environmental components or covariates of disease and their interactions with genes in genome-wide association studies. The workshop was supported by the Genes, Environment, and Health Initiative (GEI). GEI is a four-year NIH-wide program in the Presidentís budget to identify major genetic susceptibility factors for disease and to develop technologies for reliable and reproducible measurement of potential causative environmental exposures. Participants in this GEI workshop listened to presentations and participated in discussions on issues pertaining to analysis of genome-wide association studies with a gene-environment interaction component. Additionally, a poster session was held to facilitate interaction amongst investigators and their students/trainees.

This workshop helped to:

  • Identify analytical issues for genome-wide association studies
  • Identify unique issues to analyzing gene-environment interactions
  • Promote discussion among researchers performing genome-wide association

    Workshop co-chairs:

  • Lon Cardon, Ph.D., Head of Genetics, GlaxoSmithKline
  • Nancy J. Cox, Ph.D., Professor, Departments of Medicine (Section Chief - Genetic Medicine) and Human Genetics, University of Chicago


  • Chris Amos, Ph.D., University of Texas M.D. Anderson Cancer Center
  • Lon Cardon, Ph.D., GlaxoSmithKline
  • David V. Conti, Ph.D., University of Southern California
  • Nancy J. Cox, Ph.D., The University of Chicago
  • Patty S. Freedson, Ph.D., University of Massachusetts, Amherst
  • Stacey Gabriel, Ph.D., Broad Institute of MIT and Harvard
  • Federico Goodsaid, Ph.D., U.S. Food and Drug Administration
  • Alan E. Guttmacher, M.D., National Human Genome Research Institute/NIH
  • Hakon Hakonarson, M.D., Ph.D., The Children's Hospital of Philadelphia
  • Eugene Houseman, Sc.D., University of Massachusetts, Lowell
  • Charles Lee, Ph.D., FACMG, Brigham and Women's Hospital, Harvard Medical School
  • Yves A. Lussier, M.D., The University of Chicago
  • Teri Manolio, M.D., Ph.D., National Human Genome Research Institute/NIH
  • Christopher O'Donnell, M.D., M.P.H., National Heart, Lung, and Blood Institute/NIH
  • Michael Province, Ph.D., Washington University St. Louis
  • Noah A. Rosenberg, Ph.D., University of Michigan Medical School
  • Ingo Ruczinski, Ph.D., Johns Hopkins University
  • Clarice Weinberg, Ph.D., National Institute of Environmental Health Sciences/NIH
  • Brenda Weis, Ph.D., National Insitute on Alcohol Abuse and Alcoholism/NIH

    The Workshop Organizing Committee:

  • Dina N. Paltoo, Ph.D., M.P.H., Committee Chair, National Heart, Lung, and Blood Institute/NIH
  • Thomas Lehner, Ph.D., M.P.H., National Institute of Mental Health/NIH
  • Yin Yao, Ph.D., National Institute of Mental Health/NIH
  • Rebekah Rasooly, Ph.D., National Institute of Diabetes and Digestive and Kidney Diseases/NIH
  • Cashell Jaquish, Ph.D., National Heart, Lung, and Blood Institute/NIH
  • Gang Zheng, Ph.D., National Heart, Lung, and Blood Institute/NIH

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    This page last updated: July 16, 2008