Dear [Estrogen-only trial participant]:
I am writing to tell you important news about the
WHI Hormone Program. Although you are not in the Hormone Program, we
want you to be aware of this new information. The enclosed "WHI HRT Update"
describes this news.
The WHI Data and Safety Monitoring Board (DSMB)
has recommended that all other WHI studies continue. The DSMB will continue to
review the data every 6 months and we will inform you immediately if they have
new recommendations. What are we asking you to do?
- Please continue to participate in the WHI
program(s) you joined. There are still many important questions to answer
about women's health.
- Continue your regularly scheduled clinic
I have asked the Clinical Coordinating Center to
send you this letter. More information is available in the attached "WHI HRT
Update" and on the World Wide Web at: http://www.whi.org. Please share this
information with your health care provider.
These results are enormously important and will
inform millions of women and their doctors worldwide about the risks and
benefits of estrogen plus progestin. The findings from this study could not
have been predicted when we began in 1993. You are a vital part of the WHI,
which is expected to influence medical care for current and future
Thank you for your dedication, both past and
future, to the Women's Health
Claude Lenfant, MD
National Heart, Lung, and Blood