| The
title of each RFA/PA and total funding awarded for each initiative
(cumulative through FY 2002) are listed under the relevant research
recommendations from the 1996 National Sleep Research Plan.
In some instances, an individual initiative applies to more
than 1 recommendation and is therefore listed under each relevant
recommendation.
1996 SLEEP DISORDERS
RESEARCH PLAN RESEARCH RECOMMENDATIONS
Basic Science Research
Recommendations
1. Increase efforts
to understand the basic mechanisms responsible for sleep by
applying molecular biological approaches in concert with techniques
of cellular and systems neurobiology
2. Conduct basic
studies to understand the brain mechanisms responsible for sleepiness
3. Study basic mechanisms
underlying the interaction between the circadian and neurophysiological
systems that regulate sleep and wakefulness.
4. Characterize the
genetic factors controlling the basic mechanisms of sleep.
5. Increase research
efforts to elucidate the fundamental functions of sleep.
|
Title |
Participating
Institutes/Centers
|
Total Costs
Awarded (through FY '02)
|
|
Interrelationships
Between Sleep and Heart, Lung, and Blood Diseases: HL01-009
*; ** |
NHLBI; NIDA |
$1,357,253 |
|
Research on
Alcohol and Sleep: AA00-005 *; ** |
NIAAA |
$4,512,605 |
|
Oxygen Sensing
During Intermittent Hypoxia: HL00-004 * |
NHLBI |
$10,673,975 |
|
Nocturnal Asthma,
Chronobiology and Sleep: HL99-011*; ** |
NHLBI |
$3,530,381 |
|
Phenotypic
Characterization of Sleep in Mice: HL99-001 |
NHLBI; NIMH;
NIA; NINDS |
$13,512,185 |
|
Bioengineering
Research Grants: PAR 99-009 |
NCI; NCRR;
NEI; NHGRI; NHLBI; NIA; NIAAA; NIAID; NIAMS; NICHD; NIDA;
NIDCD; NIMH; NINDS; NINR; NLM |
$546,594 |
|
Research on
Musculoskeletal Fitness and Sports Medicine: PA97-025
* |
NIAMS; NICHD;
NINR |
$999,146 |
| SCOR in Neurobiology
of Sleep & Sleep Apnea: HL96-014 *; ** |
NHLBI |
$18,553,207 |
|
Molecular Biology
and Genetics of Sleep and Sleep Disorders: HL96-015 * |
NHLBI; NIMH;
NICHD |
$7,335,059 |
|
Basic and Clinical
Research on Sleep & Wakefulness: PA95-014 * |
NIA; NIAAA;
NICHD; NIDA; NHLBI; NIMH; NINDS; NINR |
$28,384,156 |
* Also listed under
Patient Oriented Research Recommendations
** Also listed under Applied Research Recommendations
Patient-Oriented
Research Recommendations
1. Identify the genetic
basis of sleep disorders that have a genetic component.
2. Conduct epidemiological
research to assess prevalence, risk factors, and long-term consequences
of common sleep disorders and determine the role of ethnicity,
age, and gender in their causation.
3. Conduct outcomes
research and clinical trials on the management of common sleep
disorders.
4. Develop new technological
approaches for diagnosis of sleep disorders, screening for sleep
disorders among high-risk populations in whom sleepiness presents
a particular danger (e.g., transportation workers), monitoring
the effectiveness of therapy, and detecting abnormalities of
sleep as early biological markers of psychiatric illnesses.
5. Elucidate the
pathogenesis/pathophysiology of sleep disorders and their consequences.
6. Provide the research
infrastructure needed to carry out patient-oriented research.
|
Title |
Participating
Institutes/Centers
|
Total Costs
Awarded (through FY '02)
|
|
Interrelationships
Between Sleep and Heart, Lung, and Blood Diseases: HL01-009
++ |
NHLBI; NIDA |
$1,357,253 |
|
Sleep and Sleep
Disorders in Children: HL01-006 |
NHLBI; NIMH;
NINR; NICHD |
$1,499,621 |
|
Restless Legs
Syndrome and Periodic Limb Movement Disorder: PA01-086 |
NINDS; NHLBI;
NIA; NIMH |
$334,178 |
|
Research on
Alcohol and Sleep - AA00-005 +; ++ |
NIAAA |
$4,512,605 |
|
Ancillary Studies
in Conjunction with SHOW Trial: DK-00-017 |
NIDDK; NHLBI;
NINR; NIAMS, NIDCR |
$1,143,165 |
|
Oxygen Sensing
During Intermittent Hypoxia: HL00-004 |
NHLBI |
$10,673,975 |
|
Biobehavioral
Research for Effective Sleep: PA00-046 +; ++ |
NINR; NHLBI;
NIA; NIAAA; NICHD; NIDA; NIMH; NCI |
$1,717,977 |
| Data Coordinating
Center for Sleep Heart Health Study: HL99-014 |
NHLBI |
$2,913,228 |
|
Nocturnal Asthma,
Chronobiology and Sleep: HL99-011 +; ++ |
NHLBI |
$3,530,381 |
|
Occupational
Safety and Health Research: PA99-143 ++ |
NIOSH; NCI;
NHLBI; NIA; NIAAA; NIAID; NIAMS; NIDCD; NIEHS |
$381,250 |
|
Obstructive
Sleep Apnea in Children: HL98-004 ++ |
NHLBI; NIDR;
NICHD |
$10,826,226 |
|
Sleep Academic
Award: HL97-015; HL96-021; HL96-006 +++ |
NHLBI |
$4,995,123 |
|
Institutional
National Research Service Award in Sleep Research: PA97-064
++ |
NHLBI; NIA;
NIAAA; NICHD; NIDA; NIMH; NINDS; NINR |
$737,625 |
|
Research on
Musculoskeletal Fitness and Sports Medicine: PA97-025
+ |
NIAMS; NICHD;
NINR |
$999,146 |
|
Molecular Biology
and Genetics of Sleep and Sleep Disorders: HL96-015 + |
NHLBI; NIMH;
NICHD |
$7,335,059 |
|
SCOR in Neurobiology
of Sleep & Sleep Apnea: HL96-014 +; ++ |
NHLBI |
$18,553,207 |
|
Basic and Clinical
Research on Sleep & Wakefulness PA95-014 +; ++ |
NHLBI; NIA;
NIAAA; NICHD; NIDA; NIMH; NINDS; NINR |
$28,384,156 |
+ Also listed under
Basic Science Research Recommendations
++ Also listed under Applied Research Recommendations
+++ Also listed under Research Training Recommendations
Continued on Page Two |
|
Continued on Page 2
Appendix Sections
|
Return
to Table of Contents
