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WORKSHOP ON SODIUM AND BLOOD PRESSURE

Bethesda Marriott Hotel
Bethesda, Maryland
January 28-29, 1999

Agenda

Day 1 - Morning Session
Part I: Welcome and Keynote Address
8:00 A.M. Introductory comments:
Drs. Claude Lenfant, Aram Chobanian, and Martha Hill
8:20 A.M. Overview of the relationship between sodium and blood pressure
Dr. Paul Whelton
Part II: Response to Dietary Sodium and Other Nutrients
8:50 A.M. Differences in dietary responsiveness to sodium intake
Dr. Myron Weinberger
9:05 A.M. Discussion--Leaders: Drs. Margo Denke, John Flack, and Steven Hunt
9:35 A.M. Interactions of sodium, potassium, magnesium and calcium in the regulation of blood pressure
Dr. Frank Sacks
9:50 A.M. Discussion--Leaders: Drs. Theodore Kotchen, David McCarron, and Laura Svetkey
10:15 A.M. BREAK
Part III: Sodium and Blood Pressure in the Young
10:30 A.M. Effects of neonatal sodium intake
Dr. Ronald Prineas
10:45 A.M. Sodium intake and blood pressure in children
Dr. Bonita Falkner
11:00 A.M. Discussion--Leaders: Drs. Gerald Berenson, Clarence Grim, and Julie Ingelfinger
11:30 A.M. General Discussion
12:00-1:00 P.M. LUNCH
Day 1 - Afternoon Session
Part IV: Clinical Trials and Clinical Studies
1:00 P.M. Meta-analysis of clinical trials of sodium reduction:
Dr. Niels Graudal
1:20 P.M. Sodium reduction in subpopulations (age, race, gender):
Dr. Richard Grimm
1:40 P.M. The prevalence of sodium sensitivity in postmenopausal women:
Dr. Janice Douglas
2:00 P.M. Sodium reduction and quality of life:
Dr. Shiriki Kumanyika
2:20 P.M. Discussion--Leaders: Drs. Lawrence Appel, David Freedman, Diana Petitti, James Robins, and Michael Stoto
3:00 P.M. BREAK
Part V: Observational Studies
3:15 P.M. INTERSALT:
Dr. Paul Elliott
3:30 P.M. Worksite Cohort, NHANES I, and Scotland Study
Dr. Christopher Sempos
3:45 P.M. MRFIT-Followup:
Dr. Jerome Cohen
4:00 P.M. Discussion--Leaders: Drs. Nancy Cook, Graham MacGregor, and Louis Tobian
4:45 P.M. ADJOURNMENT
Day 2 - Morning Session
Part VI: Other Data
8:00 A.M. Non-CVD conditions:
Dr. Daniel Jones
8:15 A.M. Left ventricular mass:
Dr. Richard Devereaux
8:30 A.M. Discussion--Leaders: Drs. Jay Cohn, Edward Frohlich and Lewis Kuller
Part VII: Physiological Effects of Very Low Sodium Intake
9:00 A.M. Renin-angiotensin system:
Dr. Suzanne Oparil
9:15 A.M. Sympathetic nervous system:
Dr. Allyn Mark
9:30 A.M. Plasma insulin, cholesterol and coagulation factors:
Dr. Brent M. Egan
9:45 A.M. Discussion--Leaders: Drs. Richard Cooper, Carlos Ferrario, and Gordon Williams
10:15 A.M. BREAK
Part VIII: Research Needs
10:30 A.M. Basic research:
Dr. Allen Cowley
10:50 A.M. Clinical/epidemiological research:
Dr. Lawrence Appel
11:10 A.M. Discussion--Leaders: Drs. Harry Gavras, David Goff, John Hall, and John McGiff
11:40 A.M. Should there be a randomized clinical trial on sodium reduction and blood pressure with morbidity/mortality as an outcome?
Drs. Daniel Jones, Alexander Logan, Ronald Prineas, and Jeremiah Stamler
12:00 General discussion: research considerations
12:30-1:30 P.M. LUNCH
Day 2 - Afternoon Session
Part IX: Public Policy Considerations
1:30 P.M. Dietary guidance public policy:
Dr. Michael McGinnis
1:50 P.M. Discussion--Leaders: Drs. Johanna Dwyer, William Harlan, Marion Nestle, and Meir Stampfer
2:30 P.M. General discussion: policy considerations
3:15 P.M. Chairpersons' concluding remarks
3:45 P.M. ADJOURNMENT

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