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Bethesda Marriott Hotel
Bethesda, Maryland
January 28-29, 1999


Day 1 - Morning Session

Part I: Welcome and Keynote Address

8:00 A.M.

Introductory comments:
Drs. Claude Lenfant, Aram Chobanian, and Martha Hill

8:20 A.M.

Overview of the relationship between sodium and blood pressure
Dr. Paul Whelton

Part II: Response to Dietary Sodium and Other Nutrients

8:50 A.M.

Differences in dietary responsiveness to sodium intake
Dr. Myron Weinberger

9:05 A.M.

Discussion--Leaders: Drs. Margo Denke, John Flack, and Steven Hunt

9:35 A.M.

Interactions of sodium, potassium, magnesium and calcium in the regulation of blood pressure
Dr. Frank Sacks

9:50 A.M.

Discussion--Leaders: Drs. Theodore Kotchen, David McCarron, and Laura Svetkey

10:15 A.M.


Part III: Sodium and Blood Pressure in the Young

10:30 A.M.

Effects of neonatal sodium intake
Dr. Ronald Prineas

10:45 A.M.

Sodium intake and blood pressure in children
Dr. Bonita Falkner

11:00 A.M.

Discussion--Leaders: Drs. Gerald Berenson, Clarence Grim, and Julie Ingelfinger

11:30 A.M.

General Discussion

12:00-1:00 P.M.


Day 1 - Afternoon Session

Part IV: Clinical Trials and Clinical Studies

1:00 P.M.

Meta-analysis of clinical trials of sodium reduction:
Dr. Niels Graudal

1:20 P.M.

Sodium reduction in subpopulations (age, race, gender):
Dr. Richard Grimm

1:40 P.M.

The prevalence of sodium sensitivity in postmenopausal women:
Dr. Janice Douglas

2:00 P.M.

Sodium reduction and quality of life:
Dr. Shiriki Kumanyika

2:20 P.M.

Discussion--Leaders: Drs. Lawrence Appel, David Freedman, Diana Petitti, James Robins, and Michael Stoto

3:00 P.M.


Part V: Observational Studies

3:15 P.M.

Dr. Paul Elliott

3:30 P.M.

Worksite Cohort, NHANES I, and Scotland Study
Dr. Christopher Sempos

3:45 P.M.

Dr. Jerome Cohen

4:00 P.M.

Discussion--Leaders: Drs. Nancy Cook, Graham MacGregor, and Louis Tobian

4:45 P.M.


Day 2 - Morning Session

Part VI: Other Data

8:00 A.M.

Non-CVD conditions:
Dr. Daniel Jones

8:15 A.M.

Left ventricular mass:
Dr. Richard Devereaux

8:30 A.M.

Discussion--Leaders: Drs. Jay Cohn, Edward Frohlich and Lewis Kuller

Part VII: Physiological Effects of Very Low Sodium Intake

9:00 A.M.

Renin-angiotensin system:
Dr. Suzanne Oparil

9:15 A.M.

Sympathetic nervous system:
Dr. Allyn Mark

9:30 A.M.

Plasma insulin, cholesterol and coagulation factors:
Dr. Brent M. Egan

9:45 A.M.

Discussion--Leaders: Drs. Richard Cooper, Carlos Ferrario, and Gordon Williams

10:15 A.M.


Part VIII: Research Needs

10:30 A.M.

Basic research:
Dr. Allen Cowley

10:50 A.M.

Clinical/epidemiological research:
Dr. Lawrence Appel

11:10 A.M.

Discussion--Leaders: Drs. Harry Gavras, David Goff, John Hall, and John McGiff

11:40 A.M.

Should there be a randomized clinical trial on sodium reduction and blood pressure with morbidity/mortality as an outcome?
Drs. Daniel Jones, Alexander Logan, Ronald Prineas, and Jeremiah Stamler


General discussion: research considerations

12:30-1:30 P.M.


Day 2 - Afternoon Session

Part IX: Public Policy Considerations

1:30 P.M.

Dietary guidance public policy:
Dr. Michael McGinnis

1:50 P.M.

Discussion--Leaders: Drs. Johanna Dwyer, William Harlan, Marion Nestle, and Meir Stampfer

2:30 P.M.

General discussion: policy considerations

3:15 P.M.

Chairpersons' concluding remarks

3:45 P.M.


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