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DEPARTMENT OF HEALTH AND HUMAN SERVICES
National Institutes of Health National Heart Lung and Blood Institute

Research Agenda on Complications of Hemophilia and Other Bleeding Disorders

Harold Varmus, M.D.
Director, NIH
April, 1999


The complete report is available in one PDF file (67 K), which is ideal for printing and reading off-line. Information on Adobe's PDF file is also available.


Table of Contents

Executive Summary
Introduction
Background

Treatment of Hemophilia and Other Bleeding Disorders
Improvements in Blood Safety
Complications of Hemophilia
Complications of Other Bleeding Disorders
Finding a Cure

Research on COmplications of Hemophilia

Mechanisms of Bleeding and Clotting
Antibody/Inhibitor Formation
Gene Therapy for Hemophilia
Blood-Borne Infectious Agents

  • Human Immunodeficiency Virus (HIV)
  • Hepatitis C Virus (HCV)

Blood Safety

  • HIV and Hepatitis
  • Creutzfeldt-JakobDisease(CJD)

Behavioral Research


Monitoring the Blood Supply

Coordinating Committees

Public Health Service (PHS) Blood Safety Committee
DHHS Advisory Committee on Blood Safety and Availability (ACBSA)
Trans-Angency Hepatitis Working Group
Trans-NIH Hepatitis C Virus Working Group
Other Coordinating Groups


Conclusion




8/31/99




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