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How Can Thrombotic Thrombocytopenic Purpura Be Prevented?

Both inherited and acquired thrombotic thrombocytopenic purpura (TTP) occur suddenly with no clear cause. You can't prevent either type.

If you've had TTP, watch for signs and symptoms of a relapse (flareup). (For more information, go to "Living With Thrombotic Thrombocytopenic Purpura.")

Ask your doctor about factors that may trigger TTP or a flareup, including:

  • Some diseases or conditions, such as pregnancy, cancer, HIV, lupus, or infections.
  • Some medical procedures, such as surgery and blood and marrow stem cell transplant.
  • Some medicines, such as ticlopidine, clopidogrel, cyclosporine A, chemotherapy, and hormone therapy and estrogens. If you take any of these medicines, your doctor may prescribe a different medicine.
  • Quinine, which is a substance often found in tonic water and nutritional health products.
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March 21, 2014 Last Updated Icon

The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.