Explore Peripheral Arterial Disease
Many people who have peripheral arterial disease (P.A.D.) don't have any signs or symptoms. Others may have many signs and symptoms.
Even if you don't have signs or symptoms, ask your doctor whether you should get checked for P.A.D. if you're:
People who have P.A.D. may have symptoms when walking or climbing stairs. These symptoms may include pain, numbness, aching, or heaviness in the leg muscles.
Symptoms also may include cramping in the affected leg(s) and in the buttocks, thighs, calves, and feet. Symptoms may ease after resting.
These symptoms are called intermittent claudication. During physical activity, your muscles need increased blood flow. If your blood vessels are narrowed or blocked, your muscles won't get enough blood, which will lead to symptoms. When resting, the muscles need less blood flow, so the symptoms will go away.
About 10 percent of people who have P.A.D. have claudication. This symptom is more likely in people who also have atherosclerosis in other arteries.
Other signs and symptoms of P.A.D. include:
Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. To find clinical trials that are currently underway for Peripheral Arterial Disease, visit www.clinicaltrials.gov.
September 2, 2014
Gary H. Gibbons
Researcher Brings Medicine One Step Closer to Widely Available Cure for Sickle Cell Disease
The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.