The exact cause of mitral valve prolapse (MVP) isn't known. Most people who have the condition are born with it. MVP tends to run in families. Also, it's more common in people who are born with connective tissue disorders, such as Marfan syndrome.
In people who have MVP, the mitral valve may be abnormal in the following ways:
These problems can keep the valve from making a tight seal. Some people's valves are abnormal in more than one way.
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