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Who Is at Risk for Mitral Valve Prolapse?

Mitral valve prolapse (MVP) affects people of all ages and both sexes. MVP that causes complications or severe symptoms most often occurs in men older than 50.

Certain conditions increase the risk of MVP, including:

  • Connective tissue disorders, such as Marfan syndrome
  • Scoliosis (SKO-le-O-sis) and other skeletal problems
  • Some types of muscular dystrophy
  • Graves disease
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Mitral Valve Prolapse Clinical Trials

Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. To find clinical trials that are currently underway for Mitral Valve Prolapse, visit

July 01, 2011 Last Updated Icon

The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.