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Who Needs a Lung Transplant?

Your doctor may recommend a lung transplant if you have severe lung disease that's getting worse. If your condition is so serious that other treatments don't work, a lung transplant may be the only option.

Lung transplants most often are used to treat people who have severe:

  • COPD (chronic obstructive pulmonary disease). COPD is the most common reason why adults need lung transplants. COPD is a progressive disease that makes it hard to breathe. “Progressive” means the disease gets worse over time.
  • Idiopathic pulmonary fibrosis (IPF). IPF is a condition in which tissue deep in your lungs becomes thick and stiff, or scarred, over time.
  • Cystic fibrosis (CF). CF is the most common reason in children for needing a lung transplant. CF is an inherited disease that causes thick, sticky mucus to build up in the lungs. This leads to repeated, serious lung infections.
  • Alpha-1 antitrypsin deficiency (AAT deficiency). AAT deficiency is a condition that raises your risk for certain types of lung disease, especially if you smoke.
  • Pulmonary hypertension (PH). PH is increased pressure in the pulmonary arteries. These arteries carry blood from your heart to your lungs to pick up oxygen.

Applying to a Lung Transplant Program

Lung transplants are done in medical centers (large hospitals) where the staff has a lot of organ transplant experience. If you need a lung transplant, you must apply to a center's transplant program.

Transplant teams at the medical center manage all parts of the center's transplant program. Transplant team members may include a:

  • Thoracic (THOR-as-ik) surgeon. This is a doctor who does lung and chest surgeries.
  • Pulmonologist. This is a doctor who specializes in lung diseases and conditions.
  • Cardiologist. This is a doctor who specializes in heart diseases and conditions.
  • Immunologist. This is a doctor who specializes in immune system disorders.
  • Respiratory (RES-pi-rah-tor-e) technician. This is a person who cares for people who have breathing and lung problems.
  • Transplant coordinator. This is a person who arranges the surgery.

Other team members may include a social worker, psychiatrist, financial coordinator, and other specialists and medical personnel, such as a nutritionist and nurses.

The transplant team will need to find out whether you're a candidate for a lung transplant. They will want to make sure you're healthy enough to have the surgery and go through a recovery program.

To do this, they will ask about your medical history. The team will want to know whether you have other serious illnesses or conditions, such as cancer, HIV, or hepatitis. They also will ask whether you've had a major chest surgery. A previous chest surgery may make it hard to do a lung transplant.

The team also will want to know whether you smoke or use alcohol or drugs.

You also will have tests to show whether you're healthy enough for a lung transplant. Tests may include:

  • Lung function tests. These tests measure how much air you can breathe in and out, how fast you can breathe air out, and how well your lungs deliver oxygen to your blood.
  • Blood tests. Blood tests help doctors check for certain diseases and conditions. They also help check the function of your organs and show how well treatments are working.
  • Chest CT scan. This test creates precise pictures of the structures inside your chest, such as your lungs.
  • EKG (electrocardiogram). This test detects and records the heart's electrical activity.
  • Echocardiography (echo). Echo uses sound waves to create pictures of your heart.
  • Right cardiac catheterization. This test measures blood pressure in the right side of your heart. The results give clues about heart valve disease, heart failure, or lung problems.

You'll talk with team members to make sure you're mentally and emotionally willing to accept the risks of the transplant process and later treatment. The team may ask whether you have a good support network of family and friends.

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Lung Transplant Clinical Trials

Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. To find clinical trials that are currently underway for Lung Transplant, visit www.clinicaltrials.gov.


 
May 01, 2011 Last Updated Icon

The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.